The largest domestic hydrogen fuel cell reactor manufacturer Sinosynergy filed a prospectus on the HKEX,hoping to expand its production capacity through financing.In the evening of November 22nd,the HKEX released the ...The largest domestic hydrogen fuel cell reactor manufacturer Sinosynergy filed a prospectus on the HKEX,hoping to expand its production capacity through financing.In the evening of November 22nd,the HKEX released the prospectus of Sinosynergy.Huatai International is its sole sponsor.展开更多
Frequent landslide events affect the Kathmandu Kyirong Highway(KKH),one of the most strategic Sino-Nepal highways,with multiple social effects.Amongst them,the impacts on local tourism,although being substantial,have ...Frequent landslide events affect the Kathmandu Kyirong Highway(KKH),one of the most strategic Sino-Nepal highways,with multiple social effects.Amongst them,the impacts on local tourism,although being substantial,have not been studied so far.The aim of this research is to analyze the characteristics of such landslides and their influence on road damages and/or blockages as well as on local tourism industry.We analyzed the co-seismic landslides triggered by the Gorkha Earthquake,2015(7.8 Mw),the post-seismic landslides that occurred during the monsoons following the earthquake,as well as landslides which occurred or reactivated in 2018,with relation to the damage that they caused to the highway.High resolution satellite images from 2015 to 2018,and field data were used for the analysis.The Langtang avalanche that locates off the highway was also mapped due to its high impacts on tourism.Between 2015 and 2018,the number of road damaging landslides in the Betrawati-Rasuwagadhi section of KKH(where Dhunche and Syafrubesi towns are located)was 101 in the main track(MT)and 103 in the new track(NT),with respective average density of 1.46/km and 3.63/km.The dominant observed landslide types were debris slides and rock falls.Landslides were mostly concentrated in the locations with the following characteristics:1)having higher elevated area,2)being located with the‘main central thrust’and other lineaments’belts,3)belonging to the Proterozoic lesser Himalayan rocks,4)having a slope gradient of 25°-45°,5)having northern,western and southern slope aspect,6)being subjected to average annual rainfall of higher than 1,000 mm,and 7)having less than 4 km distance from the past earthquake epicenters.The results further indicated that 7 rain-induced and 4 co-and post-seismic landslides have great impact on tourist flows.An impact analysis was also assessed through a door to door questionnaire survey with local hotel operators from Dhunche and Syafrubesi towns(n=29+31).The results reveal that out of six rigorously affected sectors by landslides leading to road blockage,tourism business is the most impacted livelihood sector in these towns.The reduction of visitors in different hotels ranged from 50%-100%in Dhunche and 70%-100%in Syafrubesi for the first year aftermath of the tremor.This is higher than the respective 5%-50%tourist reduction due to raininduced landslides.Using as a reference the base year 2014,the income loss of hotels in both towns was found to be 50%-100%in 2015,20%-100%in 2016,5%-75%in 2017,and similar to 35%in 2018.These results provide insights on the synergic effect of contributing factors for cut slope as well as down slope instability along mountainous motorways and their impact on income sources for local communities.展开更多
Objective To compare the efficacy, side effects and acceptability of two Sino-implants with Norplant Methods A randomized, prospective multicenter comparative clinical study was conducted in 10 clinical centers in ...Objective To compare the efficacy, side effects and acceptability of two Sino-implants with Norplant Methods A randomized, prospective multicenter comparative clinical study was conducted in 10 clinical centers in China. Results Totally 1 001, 1 000 and 998 cases were recruited for Sino-implant No. I, No. II and Norplant, respectively, in 1993. The follow-up rate was 99.8% totally in 5 years. Three and five pregnancies occurred respectively in Sino-implant No. I and No. II group, while no pregnancy occurred in the Norplant group. The cumulative pregnancy rate was 0.4, 0.7 and 0 per 100 women respectively in implant No.I, No. II and Norplant group for five years, meaning that there was no statistical difference. There was no ectopic pregnancy in the three groups. The cumulative discontinuation rates at the end of five years were not significantly different among the three groups, either. Men- strual problems were the main reason for termination. The menstrual blood loss decreased significantly and no serious health problems arose fromimplants use. Conclusion The two Sino-implants provided similar high efficacy and safety to Norplant, therefore, they can be used by women at reproductive age who are from different areas,different of races, educational background and occupation.展开更多
The purpose of this study was to use a kind of safe,long acting and reversible hormonal regimen for male contraception .The studied regimen was a subdermal insertion of a two rod implant (Sino implant, each rod c...The purpose of this study was to use a kind of safe,long acting and reversible hormonal regimen for male contraception .The studied regimen was a subdermal insertion of a two rod implant (Sino implant, each rod containing 75 mg levenorgestrel LNG) in each subject's forearm, followed 3 weeks after by monthly injection of TU (Testosterone Undecanoate 250 mg) for 3 months. Eighteen weeks after implantation, the Sino implant was removed. There were altogether 16 male volunteers recruited in the entire research program. Among them 6 cases reached azoospermia; one case reached oligozoospermia (sperm density <3 million/ml); 5 cases' sperm density declined greatly, the lowest to be 5.7±1.3 million/ml; the other four cases' sperm density also declined, but remained within normal range (above 20 million/ml), the lowest to be 24.5±9.0 million/ml. The duration to reach azoospermia was 16.7±0.5 weeks. The duration to resume to normal range of sperm density was 8.2±2.5 weeks in the subjects with azoospermia and oligozoospermia. In the first two weeks after insertion the LNG release of Sino implant's mean serum LNG level was about 0.38 ng/ml, in the rest of the time the LNG levels in blood was rather constant about 0.24 ng/ml. Routine analyses of blood and urine, liver and kidney functions, and blood chemistry including those parameters (TG,TC,HDL C,LDL C) of lipid metabolism didn't change much throughout the research. All the subjects' libido and sex function were well kept. Clinical observation didn't show any other adverse effects during the research.展开更多
<strong>Background:</strong> Computed tomography (CT) Scan is the imaging of choice for the diagnosis of sino nasal (SN) pathologies in sub-Saharan African setting. However, it is often requested by non ex...<strong>Background:</strong> Computed tomography (CT) Scan is the imaging of choice for the diagnosis of sino nasal (SN) pathologies in sub-Saharan African setting. However, it is often requested by non experienced practitioners. We aimed to describe the utility and the appropriateness of CT Scan request forms and results in the diagnosis of SN pathologies. <strong>Method:</strong> We conducted a retrospective cross-sectional study in four health facilities in Yaoundé, Cameroun, from October 2018 to September 2019. All patients to whom SN CT Scan was performed were called for an appointment. After informed consent, data on the appropriateness and conformity of the request form were collected and compared to the guidelines of the French society of radiology. CT Scan results were also collected and the quality of the report was evaluated. <strong>Results:</strong> A total of 206 SN CT Scan request forms and reports were included, with a mean patient age of 37.7 ± 16.1 years. The request form was conformed to guidelines in 8.3% of cases and was found appropriate in 62.6% of cases. No CT Scan report had all the items required, and 159 (77.2%) reports were useful. The most common diagnosis in patients with abnormal results was chronic sinusitis (49.5%) and SN polyp or polyposis (19.4%). <strong>Conclusion:</strong> Most of SN CT Scan requested were appropriate and useful. However, the conformity of request forms and reports to the guidelines is low. Suggesting the need for capacity building for the diagnosis of SN pathologies especially for non specialists like general practitioners and nurses.展开更多
文摘The largest domestic hydrogen fuel cell reactor manufacturer Sinosynergy filed a prospectus on the HKEX,hoping to expand its production capacity through financing.In the evening of November 22nd,the HKEX released the prospectus of Sinosynergy.Huatai International is its sole sponsor.
基金financial support from Major International(Regional)Joint Research Project(Grant No.41520104002)Key Research Program of Frontier Sciences,Chinese Academy of Sciences(Grant No.QYZDY-SSW-DQC006)+3 种基金International Partnership Program of Chinese Academy of Sciences(grant number 131551KYSB20180042)Strategic Priority Research Program of Chinese Academy of Sciences(Grant No XDA20030301)Organization for women in Science for Developing World(OWSD)Swedish International Development Corporation Agency(SIDA)。
文摘Frequent landslide events affect the Kathmandu Kyirong Highway(KKH),one of the most strategic Sino-Nepal highways,with multiple social effects.Amongst them,the impacts on local tourism,although being substantial,have not been studied so far.The aim of this research is to analyze the characteristics of such landslides and their influence on road damages and/or blockages as well as on local tourism industry.We analyzed the co-seismic landslides triggered by the Gorkha Earthquake,2015(7.8 Mw),the post-seismic landslides that occurred during the monsoons following the earthquake,as well as landslides which occurred or reactivated in 2018,with relation to the damage that they caused to the highway.High resolution satellite images from 2015 to 2018,and field data were used for the analysis.The Langtang avalanche that locates off the highway was also mapped due to its high impacts on tourism.Between 2015 and 2018,the number of road damaging landslides in the Betrawati-Rasuwagadhi section of KKH(where Dhunche and Syafrubesi towns are located)was 101 in the main track(MT)and 103 in the new track(NT),with respective average density of 1.46/km and 3.63/km.The dominant observed landslide types were debris slides and rock falls.Landslides were mostly concentrated in the locations with the following characteristics:1)having higher elevated area,2)being located with the‘main central thrust’and other lineaments’belts,3)belonging to the Proterozoic lesser Himalayan rocks,4)having a slope gradient of 25°-45°,5)having northern,western and southern slope aspect,6)being subjected to average annual rainfall of higher than 1,000 mm,and 7)having less than 4 km distance from the past earthquake epicenters.The results further indicated that 7 rain-induced and 4 co-and post-seismic landslides have great impact on tourist flows.An impact analysis was also assessed through a door to door questionnaire survey with local hotel operators from Dhunche and Syafrubesi towns(n=29+31).The results reveal that out of six rigorously affected sectors by landslides leading to road blockage,tourism business is the most impacted livelihood sector in these towns.The reduction of visitors in different hotels ranged from 50%-100%in Dhunche and 70%-100%in Syafrubesi for the first year aftermath of the tremor.This is higher than the respective 5%-50%tourist reduction due to raininduced landslides.Using as a reference the base year 2014,the income loss of hotels in both towns was found to be 50%-100%in 2015,20%-100%in 2016,5%-75%in 2017,and similar to 35%in 2018.These results provide insights on the synergic effect of contributing factors for cut slope as well as down slope instability along mountainous motorways and their impact on income sources for local communities.
基金This study was supported by fund from National Population and Family Planning Commission
文摘Objective To compare the efficacy, side effects and acceptability of two Sino-implants with Norplant Methods A randomized, prospective multicenter comparative clinical study was conducted in 10 clinical centers in China. Results Totally 1 001, 1 000 and 998 cases were recruited for Sino-implant No. I, No. II and Norplant, respectively, in 1993. The follow-up rate was 99.8% totally in 5 years. Three and five pregnancies occurred respectively in Sino-implant No. I and No. II group, while no pregnancy occurred in the Norplant group. The cumulative pregnancy rate was 0.4, 0.7 and 0 per 100 women respectively in implant No.I, No. II and Norplant group for five years, meaning that there was no statistical difference. There was no ectopic pregnancy in the three groups. The cumulative discontinuation rates at the end of five years were not significantly different among the three groups, either. Men- strual problems were the main reason for termination. The menstrual blood loss decreased significantly and no serious health problems arose fromimplants use. Conclusion The two Sino-implants provided similar high efficacy and safety to Norplant, therefore, they can be used by women at reproductive age who are from different areas,different of races, educational background and occupation.
文摘The purpose of this study was to use a kind of safe,long acting and reversible hormonal regimen for male contraception .The studied regimen was a subdermal insertion of a two rod implant (Sino implant, each rod containing 75 mg levenorgestrel LNG) in each subject's forearm, followed 3 weeks after by monthly injection of TU (Testosterone Undecanoate 250 mg) for 3 months. Eighteen weeks after implantation, the Sino implant was removed. There were altogether 16 male volunteers recruited in the entire research program. Among them 6 cases reached azoospermia; one case reached oligozoospermia (sperm density <3 million/ml); 5 cases' sperm density declined greatly, the lowest to be 5.7±1.3 million/ml; the other four cases' sperm density also declined, but remained within normal range (above 20 million/ml), the lowest to be 24.5±9.0 million/ml. The duration to reach azoospermia was 16.7±0.5 weeks. The duration to resume to normal range of sperm density was 8.2±2.5 weeks in the subjects with azoospermia and oligozoospermia. In the first two weeks after insertion the LNG release of Sino implant's mean serum LNG level was about 0.38 ng/ml, in the rest of the time the LNG levels in blood was rather constant about 0.24 ng/ml. Routine analyses of blood and urine, liver and kidney functions, and blood chemistry including those parameters (TG,TC,HDL C,LDL C) of lipid metabolism didn't change much throughout the research. All the subjects' libido and sex function were well kept. Clinical observation didn't show any other adverse effects during the research.
文摘<strong>Background:</strong> Computed tomography (CT) Scan is the imaging of choice for the diagnosis of sino nasal (SN) pathologies in sub-Saharan African setting. However, it is often requested by non experienced practitioners. We aimed to describe the utility and the appropriateness of CT Scan request forms and results in the diagnosis of SN pathologies. <strong>Method:</strong> We conducted a retrospective cross-sectional study in four health facilities in Yaoundé, Cameroun, from October 2018 to September 2019. All patients to whom SN CT Scan was performed were called for an appointment. After informed consent, data on the appropriateness and conformity of the request form were collected and compared to the guidelines of the French society of radiology. CT Scan results were also collected and the quality of the report was evaluated. <strong>Results:</strong> A total of 206 SN CT Scan request forms and reports were included, with a mean patient age of 37.7 ± 16.1 years. The request form was conformed to guidelines in 8.3% of cases and was found appropriate in 62.6% of cases. No CT Scan report had all the items required, and 159 (77.2%) reports were useful. The most common diagnosis in patients with abnormal results was chronic sinusitis (49.5%) and SN polyp or polyposis (19.4%). <strong>Conclusion:</strong> Most of SN CT Scan requested were appropriate and useful. However, the conformity of request forms and reports to the guidelines is low. Suggesting the need for capacity building for the diagnosis of SN pathologies especially for non specialists like general practitioners and nurses.
