In the application of large-scale ancient site protection, it is necessary to continuously monitor the ambient light, temperature, humidity and so on. However, it is impractical to frequently replace the nodes’ batte...In the application of large-scale ancient site protection, it is necessary to continuously monitor the ambient light, temperature, humidity and so on. However, it is impractical to frequently replace the nodes’ battery in the protected areas. So, the key methods to prolong the network lifetime are to aggregate the collected data and reduce the number of transferring messages. In this paper a Lightweight Data Aggregation Protocol (LDAP) based on the characteristics of the environmental changes in ancient sites is proposed. It has been implemented in the Lab with a dozen of MICAz motes and deployed in the real ancient sites. The result shows that LDAP is effective in reducing the number of transferring packets and satisfies the real application requirements.展开更多
Post-translational modification (PTM) increases the functional diversity of proteins by introducing new functional groups to the side chain of amino acid of a protein. Among all amino acid residues, the side chain of ...Post-translational modification (PTM) increases the functional diversity of proteins by introducing new functional groups to the side chain of amino acid of a protein. Among all amino acid residues, the side chain of lysine (K) can undergo many types of PTM, called K-PTM, such as “acetylation”, “crotonylation”, “methylation” and “succinylation” and also responsible for occurring multiple PTM in the same lysine of a protein which leads to the requirement of multi-label PTM site identification. However, most of the existing computational methods have been established to predict various single-label PTM sites and a very few have been developed to solve multi-label issue which needs further improvement. Here, we have developed a computational tool termed mLysPTMpred to predict multi-label lysine PTM sites by 1) incorporating the sequence-coupled information into the general pseudo amino acid composition, 2) balancing the effect of skewed training dataset by Different Error Cost method, and 3) constructing a multi-label predictor using a combination of support vector machine (SVM). This predictor achieved 83.73% accuracy in predicting the multi-label PTM site of K-PTM types. Moreover, all the experimental results along with accuracy outperformed than the existing predictor iPTM-mLys. A user-friendly web server of mLysPTMpred is available at http://research.ru.ac.bd/mLysPTMpred/.展开更多
我国正在进行大口径单天线和阵列射电望远镜的建设和预研工作。为保障射电望远镜前期建设工作的开展,首先需要找到满足电磁环境要求的台址,本文使用搬移式电磁环境监测装备在广东省清远市阳山县杜步镇、水口镇等预选台址开展了电磁环境...我国正在进行大口径单天线和阵列射电望远镜的建设和预研工作。为保障射电望远镜前期建设工作的开展,首先需要找到满足电磁环境要求的台址,本文使用搬移式电磁环境监测装备在广东省清远市阳山县杜步镇、水口镇等预选台址开展了电磁环境监测,并对广州市白云区帽峰山开展对比测试,采用一种干扰阈值判断方法对电磁环境监测数据进行了分析。分析结果显示,位于清远市阳山县杜步镇附近的洼地射频干扰(radio frequency interference,RFI)数量少且强度弱,该洼地远离城市中心,经济活动少,周围群山环抱,具有良好的电磁隔离性,适合大口径单天线和阵列射电望远镜的建设。本文的数据分析结果可为大口径射电望远镜的选址提供依据。展开更多
文摘In the application of large-scale ancient site protection, it is necessary to continuously monitor the ambient light, temperature, humidity and so on. However, it is impractical to frequently replace the nodes’ battery in the protected areas. So, the key methods to prolong the network lifetime are to aggregate the collected data and reduce the number of transferring messages. In this paper a Lightweight Data Aggregation Protocol (LDAP) based on the characteristics of the environmental changes in ancient sites is proposed. It has been implemented in the Lab with a dozen of MICAz motes and deployed in the real ancient sites. The result shows that LDAP is effective in reducing the number of transferring packets and satisfies the real application requirements.
文摘Post-translational modification (PTM) increases the functional diversity of proteins by introducing new functional groups to the side chain of amino acid of a protein. Among all amino acid residues, the side chain of lysine (K) can undergo many types of PTM, called K-PTM, such as “acetylation”, “crotonylation”, “methylation” and “succinylation” and also responsible for occurring multiple PTM in the same lysine of a protein which leads to the requirement of multi-label PTM site identification. However, most of the existing computational methods have been established to predict various single-label PTM sites and a very few have been developed to solve multi-label issue which needs further improvement. Here, we have developed a computational tool termed mLysPTMpred to predict multi-label lysine PTM sites by 1) incorporating the sequence-coupled information into the general pseudo amino acid composition, 2) balancing the effect of skewed training dataset by Different Error Cost method, and 3) constructing a multi-label predictor using a combination of support vector machine (SVM). This predictor achieved 83.73% accuracy in predicting the multi-label PTM site of K-PTM types. Moreover, all the experimental results along with accuracy outperformed than the existing predictor iPTM-mLys. A user-friendly web server of mLysPTMpred is available at http://research.ru.ac.bd/mLysPTMpred/.
文摘我国正在进行大口径单天线和阵列射电望远镜的建设和预研工作。为保障射电望远镜前期建设工作的开展,首先需要找到满足电磁环境要求的台址,本文使用搬移式电磁环境监测装备在广东省清远市阳山县杜步镇、水口镇等预选台址开展了电磁环境监测,并对广州市白云区帽峰山开展对比测试,采用一种干扰阈值判断方法对电磁环境监测数据进行了分析。分析结果显示,位于清远市阳山县杜步镇附近的洼地射频干扰(radio frequency interference,RFI)数量少且强度弱,该洼地远离城市中心,经济活动少,周围群山环抱,具有良好的电磁隔离性,适合大口径单天线和阵列射电望远镜的建设。本文的数据分析结果可为大口径射电望远镜的选址提供依据。
