Based on 310 horizontal-component digital seismograms recorded at 14 seismic stations in Shanxi Digital Seis-mograph Network, the inelastic attenuation coefficient in Shanxi region is studied. By the methods of Atkins...Based on 310 horizontal-component digital seismograms recorded at 14 seismic stations in Shanxi Digital Seis-mograph Network, the inelastic attenuation coefficient in Shanxi region is studied. By the methods of Atkinson and Moya, the site response of each station and several source parameters are obtained and the inversion results from both methods are compared and analyzed. The frequency-dependent inelastic attenuation coefficient Q is estimated as Q( f )=323.2 f 0.506. The site responses of 14 seismic stations do not show significant amplification, which is consistent with their basement on rock. We also found the dependence of corner frequency on seismic moment, seismic moment on stress drop, source radius on stress drop.展开更多
This study addresses the changes in acceleration,pore water pressure and Fourier spectrums of different types of seismic waves with various amplitudes via large-scale shaking table tests from two sites:a sand-containi...This study addresses the changes in acceleration,pore water pressure and Fourier spectrums of different types of seismic waves with various amplitudes via large-scale shaking table tests from two sites:a sand-containing regional site and an all-clay site.Comparative analyses of the test results show that the pore water pressures in sand-soil layers of the regional site initially increase and then decrease as the amplitudes of the seismic accelerations increase.The actions of the vertical and vibrational seismic waves contribute to greater pore water pressures.The amplification coefficient of the sand-layer regional site becomes smaller as the seismic waves grow stronger,so that both sites are capable of filtering high frequencies and amplifying low frequencies of seismic waves.This is more apparent with the increase in the peak value of the acceleration,and the natural vibration frequencies of both sites decrease with the transmission of the seismic waves from the basement to the ground surface.The decreasing frequency value of the sand-containing regional site is smaller than that of the all-clay site.展开更多
Based on 310 horizontal-component digital seismograms recorded at 14 seismic stations in Shanxi Digital Seis-mograph Network, the inelastic attenuation coefficient in Shanxi region is studied. By the methods of Atkins...Based on 310 horizontal-component digital seismograms recorded at 14 seismic stations in Shanxi Digital Seis-mograph Network, the inelastic attenuation coefficient in Shanxi region is studied. By the methods of Atkinson and Moya, the site response of each station and several source parameters are obtained and the inversion results from both methods are compared and analyzed. The frequency-dependent inelastic attenuation coefficient Q is estimated as Q( f )=323.2 f 0.506. The site responses of 14 seismic stations do not show significant amplification, which is consistent with their basement on rock. We also found the dependence of corner frequency on seismic moment, seismic moment on stress drop, source radius on stress drop.展开更多
Although a great deal of research has been undertaken in the area of the annotation of gene structure, predictive techniques are still not fully developed. In this paper, based on the characteristics of base compositi...Although a great deal of research has been undertaken in the area of the annotation of gene structure, predictive techniques are still not fully developed. In this paper, based on the characteristics of base composition of sequences and conservative of nucleotides at exon/intron splicing site, a least increment of diversity al-gorithm (LIDA) is developed for studying and predicting three kinds of coding exons, introns and intergenic regions. At first, by selecting the 64 trinucleotides composition and 120 position parameters of the four bases as informational parameters, coding exon, intron and intergenic sequence are predicted. The results show that overall predicted accuracies are 91.1% and 88.4%, respectively for A. thaliana and C. ele-gans genome. Subsequently, based on the po-sition frequencies of four kinds of bases in regions near intron/coding exon boundary, initia-tion and termination site of translation, 12 position parameters are selected as diversity source. And three kinds of the coding exons are predicted by use of the LIDA. The predicted successful rates are higher than 80%. These results can be used in sequence annotation.展开更多
After description of the concept of urban feature with Nanning and Liuzhou City as example,the paper illustrated regional characteristics of Guangxi City and highlighted its cultural atmosphere of minority nationaliti...After description of the concept of urban feature with Nanning and Liuzhou City as example,the paper illustrated regional characteristics of Guangxi City and highlighted its cultural atmosphere of minority nationalities.It emphasized that only when regional urban feature was further enhanced could city development be promoted,and that only when urban feature was clearly identified could city square was characteristic.As for site selection of city square,it should follow principles of people-orientation,integrity,landscape,economy,ecology and geomancy.As for construction of city square,it should pay attention to integrate urban cultural feature based on relevant principles,and both inherit local historical culture and highlight local natural characteristic.In addition,folk artistic elements could be applied in city square,and folk artistic elements of nonmaterial culture could be integrated into the theme of city square.Material artistic elements could be also extracted and concluded as a kind of aesthetic art,reflected in concrete architectural forms.Characteristic innovation of city square should respect planning,start from city actuality,be based on self characteristics,consider citizens' willingness,and draw on local resources,so as to manifest regional cultural characteristic and promote city influence and competitiveness.展开更多
The spatiotemporal variations of the site and regional droughts in China during 1960–2009 were analyzed by applying a daily composite-drought index (CDI) to 722 stations in China's Mainland. Droughts frequently...The spatiotemporal variations of the site and regional droughts in China during 1960–2009 were analyzed by applying a daily composite-drought index (CDI) to 722 stations in China's Mainland. Droughts frequently happened in a zone extended from Southwest China to the Yellow River, North China, and the southwestern part of Northeast China, with two centers of high frequency in North China and Southwest China. In Southwest and South China, droughts tend to happen during the winter. In North China and along the Yellow River, droughts mainly occur during the winter and during May–June. During the past 50 years, the geographical distribution of site drought events showed high frequencies (0.9–1.3 times per year) in the upper Yellow River basin and North China, comparing with moderate frequencies (0.6–0.9 times per year) in Southwest China and the southwestern part of Northeast China and with lower frequencies over the middle and lower Yangtze River basin. And the frequencies increased over China's Mainland except for the upper reaches of the Yangtze River. A regional drought (RD) event is a widespread and persistent event that covers at least five adjacent sites and lasts for at least 10 days. There were 252 RD events in the past 50 years—five times per year. Most RD events lasted for 100 days and covered 100 stations, but the longest and largest RD event lasted for 307 days from 6 September 1998 to 9 July 1999 and covered 327 stations from North to Southwest China.展开更多
Building Construction employees essentially required sufficient welfare facilities such as a place for washing, shower, change over, eat and drink, a place to store and hang clothing. Yet, these fundamental necessitie...Building Construction employees essentially required sufficient welfare facilities such as a place for washing, shower, change over, eat and drink, a place to store and hang clothing. Yet, these fundamental necessities are regularly dis</span><span style="font-family:Verdana;">regarded. Decent welfare facilities can absolutely promote health and well-being</span><span style="font-family:Verdana;"> and can aid to avert contracting diseases at building construction site. The aim of this study is to examine the impact of welfare facilities on building construction workers performance in the Eastern </span><a name="_Hlk47637831"></a><span style="font-family:Verdana;">Region Ghana. The objec</span><span style="font-family:Verdana;">tives were to identify welfare facilities provided by building construction firms,</span><span style="font-family:Verdana;"> evaluate the satisfaction level of building construction firms’ employees with welfare facilities in Eastern Region, and determine the relationship between provision of welfare facilities and employee’s performance. The study employed convenient sample to investigate 80 building construction employees through questionnaires administration. Data generated from the survey was further analyzed using SPSS, weighted mean formula was used to determine the mean ranking, and descriptive and inferential statistics such as mean score, percentages, frequencies and chi square were used. The study reveals that the extent of welfare facilities at various construction sites was almost unavailability of sanitary and toilet facilities, unavailability of washing facilities, and unavailability of changing room, whiles drinking water and locker facilities were available but not sufficient. The study further finds that construction employees are dissatisfied with the condition of welfare facilities provided at their various work places. The study finally concludes that if workers are provided with decent welfare facilities at various building construction sites, it will motivate them to improve performance. </span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><a name="_Hlk47637831"></a><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;">The study recommends that</span><span style="font-family:Verdana;"> metropolitan, municipal and district authority (MMDAs) should set a task force to check the implementation of welfare facilities at construction site as the results are pointing woeful insufficiency of welfare facilities at Eastern Region construction firms in Ghana.展开更多
Recent improvement in the technologies for efficient delivery of DNA vaccines has renewed interest in the DNA-based vaccines. Several DNA-based vaccines against human enterovirus 71 (EV71), the causative agent for han...Recent improvement in the technologies for efficient delivery of DNA vaccines has renewed interest in the DNA-based vaccines. Several DNA-based vaccines against human enterovirus 71 (EV71), the causative agent for hand, foot and mouth disease (HFMD) have been developed. Here we examined the potential of improving the vaccines by inserting the EV71 5’ untranslated region (5’ UTR) containing the full length internal ribosome entry site (IRES) sequence to the EV71 VP1-based DNA vaccine constructs. Four vaccine constructs designated as 5’ UTR-VP1/EGFP, VP1/EGFP, 5’ UTR-VP1/pVAX and VP1/pVAX, were designed using the pEGFP-N1 and pVAX-1 expression vectors, respectively. Transfection of Vero cells with the vaccine constructs with the 5’-UTR (5’-UTR-VP1/EGFP and 5’ UTR-VP1/pVAX) resulted in higher percentages of cells expressing the recombinant protein in comparison to cells transfected with vectors without the 5’-UTR (67% and 57%, respectively). Higher IgG responses (29%) were obtained from mice immunized with the DNA vaccine construct with the full length 5’ UTR. The same group of mice when challenged with life EV71 produced significantly higher neutralizing antibody (NAb) titers (>5-fold). These results suggest that insertion of the EV71 5’ UTR sequence consisting of the full length IRES to the EV71 DNA vaccine constructs improved the efficacy of the constructs with enhanced elicitation of the neutralizing antibody responses.展开更多
基金National Scientific Research Target Project of China (2001-BA601B01-01-05) during the tenth Five-year Plan.
文摘Based on 310 horizontal-component digital seismograms recorded at 14 seismic stations in Shanxi Digital Seis-mograph Network, the inelastic attenuation coefficient in Shanxi region is studied. By the methods of Atkinson and Moya, the site response of each station and several source parameters are obtained and the inversion results from both methods are compared and analyzed. The frequency-dependent inelastic attenuation coefficient Q is estimated as Q( f )=323.2 f 0.506. The site responses of 14 seismic stations do not show significant amplification, which is consistent with their basement on rock. We also found the dependence of corner frequency on seismic moment, seismic moment on stress drop, source radius on stress drop.
基金National Program on Key Basic Research Project(973 Program)under Grant No.2011CB013606Program for Changjiang Scholars and Innovative Research Team in University under Grant No.IRT13057+1 种基金Key Program of National Natural Science Foundation of China under Grant No.51438004the Research Fund for the Doctoral Program of Higher Education of China under Grant No.20124410110004
文摘This study addresses the changes in acceleration,pore water pressure and Fourier spectrums of different types of seismic waves with various amplitudes via large-scale shaking table tests from two sites:a sand-containing regional site and an all-clay site.Comparative analyses of the test results show that the pore water pressures in sand-soil layers of the regional site initially increase and then decrease as the amplitudes of the seismic accelerations increase.The actions of the vertical and vibrational seismic waves contribute to greater pore water pressures.The amplification coefficient of the sand-layer regional site becomes smaller as the seismic waves grow stronger,so that both sites are capable of filtering high frequencies and amplifying low frequencies of seismic waves.This is more apparent with the increase in the peak value of the acceleration,and the natural vibration frequencies of both sites decrease with the transmission of the seismic waves from the basement to the ground surface.The decreasing frequency value of the sand-containing regional site is smaller than that of the all-clay site.
文摘Based on 310 horizontal-component digital seismograms recorded at 14 seismic stations in Shanxi Digital Seis-mograph Network, the inelastic attenuation coefficient in Shanxi region is studied. By the methods of Atkinson and Moya, the site response of each station and several source parameters are obtained and the inversion results from both methods are compared and analyzed. The frequency-dependent inelastic attenuation coefficient Q is estimated as Q( f )=323.2 f 0.506. The site responses of 14 seismic stations do not show significant amplification, which is consistent with their basement on rock. We also found the dependence of corner frequency on seismic moment, seismic moment on stress drop, source radius on stress drop.
文摘Although a great deal of research has been undertaken in the area of the annotation of gene structure, predictive techniques are still not fully developed. In this paper, based on the characteristics of base composition of sequences and conservative of nucleotides at exon/intron splicing site, a least increment of diversity al-gorithm (LIDA) is developed for studying and predicting three kinds of coding exons, introns and intergenic regions. At first, by selecting the 64 trinucleotides composition and 120 position parameters of the four bases as informational parameters, coding exon, intron and intergenic sequence are predicted. The results show that overall predicted accuracies are 91.1% and 88.4%, respectively for A. thaliana and C. ele-gans genome. Subsequently, based on the po-sition frequencies of four kinds of bases in regions near intron/coding exon boundary, initia-tion and termination site of translation, 12 position parameters are selected as diversity source. And three kinds of the coding exons are predicted by use of the LIDA. The predicted successful rates are higher than 80%. These results can be used in sequence annotation.
文摘After description of the concept of urban feature with Nanning and Liuzhou City as example,the paper illustrated regional characteristics of Guangxi City and highlighted its cultural atmosphere of minority nationalities.It emphasized that only when regional urban feature was further enhanced could city development be promoted,and that only when urban feature was clearly identified could city square was characteristic.As for site selection of city square,it should follow principles of people-orientation,integrity,landscape,economy,ecology and geomancy.As for construction of city square,it should pay attention to integrate urban cultural feature based on relevant principles,and both inherit local historical culture and highlight local natural characteristic.In addition,folk artistic elements could be applied in city square,and folk artistic elements of nonmaterial culture could be integrated into the theme of city square.Material artistic elements could be also extracted and concluded as a kind of aesthetic art,reflected in concrete architectural forms.Characteristic innovation of city square should respect planning,start from city actuality,be based on self characteristics,consider citizens' willingness,and draw on local resources,so as to manifest regional cultural characteristic and promote city influence and competitiveness.
基金supported jointly bythe National Natural Science Foundation of China (GrantNo. 40975039)the Key Technologies R&D Program(Grant No. 2009BAC51B04)+1 种基金the Chinese COPES Project (Grant No. GYHY201006018)The CDI data was provided by the Key Technologies R&D Program (GrantNo. 2007BAC29B06).
文摘The spatiotemporal variations of the site and regional droughts in China during 1960–2009 were analyzed by applying a daily composite-drought index (CDI) to 722 stations in China's Mainland. Droughts frequently happened in a zone extended from Southwest China to the Yellow River, North China, and the southwestern part of Northeast China, with two centers of high frequency in North China and Southwest China. In Southwest and South China, droughts tend to happen during the winter. In North China and along the Yellow River, droughts mainly occur during the winter and during May–June. During the past 50 years, the geographical distribution of site drought events showed high frequencies (0.9–1.3 times per year) in the upper Yellow River basin and North China, comparing with moderate frequencies (0.6–0.9 times per year) in Southwest China and the southwestern part of Northeast China and with lower frequencies over the middle and lower Yangtze River basin. And the frequencies increased over China's Mainland except for the upper reaches of the Yangtze River. A regional drought (RD) event is a widespread and persistent event that covers at least five adjacent sites and lasts for at least 10 days. There were 252 RD events in the past 50 years—five times per year. Most RD events lasted for 100 days and covered 100 stations, but the longest and largest RD event lasted for 307 days from 6 September 1998 to 9 July 1999 and covered 327 stations from North to Southwest China.
文摘Building Construction employees essentially required sufficient welfare facilities such as a place for washing, shower, change over, eat and drink, a place to store and hang clothing. Yet, these fundamental necessities are regularly dis</span><span style="font-family:Verdana;">regarded. Decent welfare facilities can absolutely promote health and well-being</span><span style="font-family:Verdana;"> and can aid to avert contracting diseases at building construction site. The aim of this study is to examine the impact of welfare facilities on building construction workers performance in the Eastern </span><a name="_Hlk47637831"></a><span style="font-family:Verdana;">Region Ghana. The objec</span><span style="font-family:Verdana;">tives were to identify welfare facilities provided by building construction firms,</span><span style="font-family:Verdana;"> evaluate the satisfaction level of building construction firms’ employees with welfare facilities in Eastern Region, and determine the relationship between provision of welfare facilities and employee’s performance. The study employed convenient sample to investigate 80 building construction employees through questionnaires administration. Data generated from the survey was further analyzed using SPSS, weighted mean formula was used to determine the mean ranking, and descriptive and inferential statistics such as mean score, percentages, frequencies and chi square were used. The study reveals that the extent of welfare facilities at various construction sites was almost unavailability of sanitary and toilet facilities, unavailability of washing facilities, and unavailability of changing room, whiles drinking water and locker facilities were available but not sufficient. The study further finds that construction employees are dissatisfied with the condition of welfare facilities provided at their various work places. The study finally concludes that if workers are provided with decent welfare facilities at various building construction sites, it will motivate them to improve performance. </span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><a name="_Hlk47637831"></a><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;">The study recommends that</span><span style="font-family:Verdana;"> metropolitan, municipal and district authority (MMDAs) should set a task force to check the implementation of welfare facilities at construction site as the results are pointing woeful insufficiency of welfare facilities at Eastern Region construction firms in Ghana.
文摘Recent improvement in the technologies for efficient delivery of DNA vaccines has renewed interest in the DNA-based vaccines. Several DNA-based vaccines against human enterovirus 71 (EV71), the causative agent for hand, foot and mouth disease (HFMD) have been developed. Here we examined the potential of improving the vaccines by inserting the EV71 5’ untranslated region (5’ UTR) containing the full length internal ribosome entry site (IRES) sequence to the EV71 VP1-based DNA vaccine constructs. Four vaccine constructs designated as 5’ UTR-VP1/EGFP, VP1/EGFP, 5’ UTR-VP1/pVAX and VP1/pVAX, were designed using the pEGFP-N1 and pVAX-1 expression vectors, respectively. Transfection of Vero cells with the vaccine constructs with the 5’-UTR (5’-UTR-VP1/EGFP and 5’ UTR-VP1/pVAX) resulted in higher percentages of cells expressing the recombinant protein in comparison to cells transfected with vectors without the 5’-UTR (67% and 57%, respectively). Higher IgG responses (29%) were obtained from mice immunized with the DNA vaccine construct with the full length 5’ UTR. The same group of mice when challenged with life EV71 produced significantly higher neutralizing antibody (NAb) titers (>5-fold). These results suggest that insertion of the EV71 5’ UTR sequence consisting of the full length IRES to the EV71 DNA vaccine constructs improved the efficacy of the constructs with enhanced elicitation of the neutralizing antibody responses.