Study on Virtual Human Skeleton System

A solution of virtual human skeleton system is proposed. Some issues on integration of anatomical geometry, biodynamics and computer animation are studied. The detailed skeleton system model that incorporates the biodynamic and geometric characteristics of a human skeleton system allows some performance studies in greater detail than that performed before. It may provide an effective and convenient way to analyze and evaluate the movement performance of a human body when the personalized anatomical data are used in the models. An example shows that the proposed solution is effective for the stated problems.

Ageing-related bone and immunity changes:insights into the complex interplay between the skeleton and the immune system

Ageing as a natural irreversible process inherently results in the functional deterioration of numerous organ systems and tissues,including the skeletal and immune systems.Recent studies have elucidated the intricate bidirectional interactions between these two systems.

MXene Hollow Spheres Supported by a C–Co Exoskeleton Grow MWCNTs for Efficient Microwave Absorption

High-performance microwave absorption(MA) materials must be studied immediately since electromagnetic pollution has become a problem that cannot be disregarded. A straightforward composite material, comprising hollow MXene spheres loaded with C–Co frameworks, was prepared to develop multiwalled carbon nanotubes(MWCNTs). A high impedance and suitable morphology were guaranteed by the C–Co exoskeleton, the attenuation ability was provided by the MWCNTs endoskeleton, and the material performance was greatly enhanced by the layered core–shell structure. When the thickness was only 2.04 mm, the effective absorption bandwidth was 5.67 GHz, and the minimum reflection loss(RLmin) was-70.70 d B. At a thickness of 1.861 mm, the sample calcined at 700 ℃ had a RLmin of-63.25 d B. All samples performed well with a reduced filler ratio of 15 wt%. This paper provides a method for making lightweight core–shell composite MA materials with magnetoelectric synergy.

Rational design of carbon skeleton interfaces for highly reversible sodium metal battery anodes

Sodium metal batteries(SMBs)have attracted increasing attention over time due to their abundance of sodium resources and low cost.However,the widespread application of SMBs as a viable technology remains a great challenge,such as uneven metallic deposition and dendrite formation during cycling.Carbon skeletons as sodiophilic hosts can alleviate the dendrite formation during the plating/stripping.For the carbon skeleton,how to rationalize the design sodiophilic interfaces between the sodium metal and carbon species remains key to developing desirable Na anodes.Herein,we fabricated four kinds of structural features for carbon skeletons using conventional calcination and flash Joule heating.The roles of conductivity,defects,oxygen content,and the distribution of graphite for the deposition of metallic sodium were discussed in detail.Based on interface engineering,the J1600 electrode,which has abundant Na-C species on its surface,showed the highest sodiophilic.There are uniform and rich F-Na species distributed in the inner solid electrolyte interface layer.This study investigated the different Na-deposition behavior in carbon hosts with distinct graphitic arrangements to pave the way for designing and optimizing advanced electrode materials.

Vacancy defect MoSeTe embedded in N and F co-doped carbon skeleton for high performance sodium ion batteries and hybrid capacitors

Sodium-ion batteries(SIBs) and hybrid capacitors(SIHCs) have garnered significant attention in energy storage due to their inherent advantages,including high energy density,cost-effectiveness,and enhanced safety.However,developing high-performance anode materials to improve sodium storage performa nce still remains a major challenge.Here,a facile one-pot method has been developed to fabricate a hybrid of MoSeTe nanosheets implanted within the N,F co-doped honeycomb carbon skeleton(MoSeTe/N,F@C).Experimental results demonstrate that the incorporation of large-sized Te atoms into MoSeTe nanosheets enlarges the layer spacing and creates abundant anion vacancies,which effectively facilitate the insertion/extraction of Na^(+) and provide numerous ion adsorption sites for rapid surface capacitive behavior.Additionally,the heteroatoms N,F co-doped honeycomb carbon skeleton with a highly conductive network can restrain the volume expansion and boost reaction kinetics within the electrode.As anticipated,the MoSeTe/N,F@C anode exhibits high reversible capacities along with exceptional cycle stability.When coupled with Na_(3)V_(2)(PO_(4))_(3)@C(NVPF@C) to form SIB full cells,the anode delivers a reversible specific capacity of 126 mA h g^(-1) after 100 cycles at 0.1 A g^(-1).Furthermore,when combined with AC to form SIHC full cells,the anode demonstrates excellent cycling stability with a reversible specific capacity of50 mA h g^(-1) keeping over 3700 cycles at 1.0 A g^(-1).In situ XRD,ex situ TEM characterization,and theoretical calculations(DFT) further confirm the reversibility of sodium storage in MoSeTe/N,F@C anode materials during electrochemical reactions,highlighting their potential for widespread practical application.This work provides new insights into the promising utilization of advanced transition metal dichalcogenides as anode materials for Na^(+)-based energy storage devices.

Terpene extract from the stem of Celastrus orbiculatus inhibits actin cytoskeleton remodelling in gastric cancer cells by regulating the protein interaction between PTBP1 and ACTN4

Adjuvant chemoradiotherapy,molecular targeted therapy,and immunotherapy are frequently employed to extend the survival of patients with advanced gastric cancer(GC).However,most of these treatments have toxic side effects,drug resistance,and limited improvements in survival and quality of life.Therefore,it is crucial to discover and develop new medications targeting GC that are highly effective and have minimal toxicity.In previous studies,the total terpene extract from the stem of Celastrus orbiculatus demonstrated anti-GC activity;however,the specific mechanism was unclear.Our research utilising coimmunoprecipitation-mass spectrometry(Co-IP-MS),polypyrimidine tract binding protein 1(ptbp1)clustered regularly interspaced short palindromic repeat-associated protein 9(Cas9)-knockout(KO)mouse model,tissue microarray,and functional experiments suggests that alpha actinin-4(ACTN4)could be a significant biomarker of GC.PTBP1 influences actin cytoskeleton restructuring in GC cells by interacting with ACTN4.Celastrus orbiculatus stem extract(COE)may directly target ACTN4 and affect the interaction between PTBP1 and ACTN4,thereby exerting anti-GC effects.

Rock skeleton models and seismic porosity inversion

By substituting rock skeleton modulus expressions into Gassmann approximate fluid equation, we obtain a seismic porosity inversion equation. However, conventional rock skeleton models and their expressions are quite different from each other, resuling in different seismic porosity inversion equations, potentially leading to difficulties in correctly applying them and evaluating their results. In response to this, a uniform relation with two adjusting parameters suitable for all rock skeleton models is established from an analysis and comparison of various conventional rock skeleton models and their expressions including the Eshelby-Walsh, Pride, Geertsma, Nur, Keys-Xu, and Krief models. By giving the two adjusting parameters specific values, different rock skeleton models with specific physical characteristics can be generated. This allows us to select the most appropriate rock skeleton model based on geological and geophysical conditions, and to develop more wise seismic porosity inversion. As an example of using this method for hydrocarbon prediction and fluid identification, we apply this improved porosity inversion, associated with rock physical data and well log data, to the ZJ basin. Research shows that the existence of an abundant hydrocarbon reservoir is dependent on a moderate porosity range, which means we can use the results of seismic porosity inversion to identify oil reservoirs and dry or water-saturated reservoirs. The seismic inversion results are closely correspond to well log porosity curves in the ZJ area, indicating that the uniform relations and inversion methods proposed in this paper are reliable and effective.

Skeletonization技术及其在深地震反射剖面解释中的应用

"深部探测技术与实验研究"(SINOPROBE)专项的启动揭开了中国"入地"计划的序幕.大规模的深地震反射剖面是该计划最重要的组成部分之一,如何从深地震反射剖面中获取更多有用的信息成为我们即将面临的重要课题.Skeletonization技术是西方国家在实施深部探测计划时发展的一项深地震剖面信息提取分析技术,对我们具有重要的借鉴意义.本文在研究前人工作的基础上,综述了Skeletonization技术的基本原理及其在国内外的发展,并在此基础上介绍了该技术在深地震反射剖面解释中的应用,最后结合我国刚刚启动的SINOPROBE计划对其进一步的发展进行了展望.

乳内动脉skeleton取材法在冠状动脉旁路移植术中的应用

目的 评价乳内动脉skeleton取材法在冠状动脉旁路移植术（CABG）中的应用及其效果。方法 277例接受CABG的患者（其中合并糖尿病33例）在术中分离乳内动脉的过程中，仅使用剪刀和钛夹来分离乳内动脉，即不附带任何周围组织的skeleton取材法游离一侧或两侧乳内动脉，其中21例糖尿病患者取用双侧乳内动脉；并观察患者术中、术后的临床结果。采用非体外循环CABG5例，体外循环CABG272例。结果 体外循环时间60～217min，平均90．1min；主动脉阻断时间30～160min，平均53．3min。手术死亡率2．2％（6／277）。手术中见乳内动脉桥质量良好，动脉桥血流量满意；术后移植血管通畅，心绞痛症状消失。取用双侧乳内动脉和糖尿病患者亦未出现更高的胸骨感染率。手术后冠状动脉造影显示乳内动脉血管桥通畅。结论 乳内动脉skeleton取材法有良好的血管桥通畅率，对患者胸骨创伤较小，对糖尿病患者取用双侧乳内动脉不再是禁忌证。

Skeleton extraction of boiler flame images based on mathematical morphology

In this paper, a method and algorithm of skeleton extraction based on binary mathematical morphology is presented. Sequential structuring elements (SEs) is also studied, which is the key problem of skeleton extraction. The examples of boiler flame image processing show that the detected skeletons can present the geometric shape of flame images well.

基于Skeleton Design的脱粒装置交互式设计系统研究

针对联合收获机脱粒装置设计过程中装备结构复杂、参数化变形设计困难以及对设计人员专业素质要求高的问题,为寻求合适的参数化设计手段,研究了基于Skeleton Design(骨架设计)的脱粒装置交互式设计系统。以纹杆滚筒式脱粒装置为研究对象,引入Skeleton Design过程体的概念,结合纹杆滚筒式脱粒装置的总体设计过程,实现脱粒装置的个性化设计与参数化建模。以VS(Microsoft Visual Studio)环境下VB.NET为开发语言,应用CATIA(Computer aided tri-dimensional interface application)二次开发接口技术与SQL Server数据库管理,将模型、参数、知识信息等数字化资源与操作平台组织起来,联合运用,通过人机交互的方式进行产品设计。系统测试表明,该系统能在降低设计人员专业性、提高开发产品准确性的同时,提高设计效率、缩短设计周期,并且易于理解和应用,增强了模型的知识继承与重用性,满足脱粒装置个性化设计要求。

神经网络Skeletonization算法在优化锅炉运行参数中的应用

对将神经网络Skeletonization算法进行改进,运用到优化调整锅炉性能参数的方法,用神经网络模型预测锅炉运行中需要优化的性能参数。通过神经网络的学习,模拟性能参数的影响因素与性能参数之间的映射函数,再通过改进Skeletonization算法对网络模型进一步计算,找出哪些影响因素对性能参数的影响较大,为快速有效准确的机组运行优化提供指导依据和方向。这种方法不仅能为机组运行优化提供直观的理论根据,同时对锅炉的运行不产生负面影响,可以实现在线优化运行。通过计算影响因素的权重值,对性能参数准确预报,为锅炉机组的性能优化调整提供便捷、准确、全面的方案。

Oviraptorosaurian Eggs (Dinosauria) with Embryonic Skeletons Discovered for the First Time in China

Two elongatoolithid dinosaur eggs from the Upper Cretaceous of Ganzhou, Jiangxi Province and the embryonic skeletons they bear are described. They represent the first oviraptorosaurian eggs with embryonic skeletons in China and provide the first example that an oospecies can be correlated to certain dinosaur taxon/taxa. The two eggs are the same as the pair of the eggs inside a female oviraptorosaurian pelvis from the same horizon of the same area in both macro- and micro-structures of the egg shells, and can he referred to the oospecies, Macroolithus yaotunensis Zhao, 1975. The morphology of the preserved part of the embryonic skeletons indicates that they may have been laid by an oviraptorid, Heyuannia huangi from Guangdong Province or a closely related oviraptorosaurian, which may have been lived in the Ganzhou area too in the Late Cretaceous. The embryonic skeletons of the two eggs are not in the same developing stage. In one of the eggs, the postzygapophysis of the preserved vertebrae are well ossified, indicating that it was just hatched.

Homogeneous bottom-growth of lithium metal anode enabled by double-gradient lithiophilic skeleton

Lithium(Li) metal is considered as the most promising anode material for the next-generation high performance Li batteries.However,the uncontrollable dendritic growth impedes its commercial application.Herein,we design a 3 D Si@carbon nanofibers(CNFs)@ZnO-ZnO-Cu skeleton(SCZ) for guiding the homogeneous bottom-growth of Li metal.The top LixSi@CNFs and bottom LiyZn@CNFs layers could form conductivity and overpotential gradient to avoid the "top-growth" of Li metal.Moreover,the top lithiophilic LixSi@CNFs layer could regulate the nucleation and deposition of Li-ions even if the lithium dendrites grow out of the skeleton under high capacity Li deposition(30 mAh cm^(-2)).As a result,the SCZ-Li||LiFePO_(4) full cell delivers a high capacity of ~104 mAh g^(-1)(~94.82% capacity retention) after 2000 cycles at 5 C, elucidating the potential application of the 3 D double-gradient Li metal composite anode.

A spatial attentive and temporal dilated(SATD)GCN for skeleton-based action recognition

Current studies have shown that the spatial-temporal graph convolutional network(STGCN)is effective for skeleton-based action recognition.However,for the existing STGCN-based methods,their temporal kernel size is usually fixed over all layers,which makes them cannot fully exploit the temporal dependency between discontinuous frames and different sequence lengths.Besides,most of these methods use average pooling to obtain global graph feature from vertex features,resulting in losing much fine-grained information for action classification.To address these issues,in this work,the authors propose a novel spatial attentive and temporal dilated graph convolutional network(SATD-GCN).It contains two important components,that is,a spatial attention pooling module(SAP)and a temporal dilated graph convolution module(TDGC).Specifically,the SAP module can select the human body joints which are beneficial for action recognition by a self-attention mechanism and alleviates the influence of data redundancy and noise.The TDGC module can effectively extract the temporal features at different time scales,which is useful to improve the temporal perception field and enhance the robustness of the model to different motion speed and sequence length.Importantly,both the SAP module and the TDGC module can be easily integrated into the ST-GCN-based models,and significantly improve their performance.Extensive experiments on two large-scale benchmark datasets,that is,NTU-RGB+D and Kinetics-Skeleton,demonstrate that the authors’method achieves the state-of-the-art performance for skeleton-based action recognition.

Effects of Ultraviolet Radiation on Skeleton Development of Broiler Chickens

Seven hundred and twenty one-day-old AA broiler chickens were randomly allocated into two groups （male and female for half）, and put into two identical closed houses with different lighting programs. The first house was illuminated by using common incandescence light, and the second one was added with ultraviolet radiation light from the second week onwards. The birds lived in a floor with litters and free access to feed and water. Temperature, humidity and immune programs in the two houses were similar. The results showed that under ultraviolet radiation, the growth speed of skeleton increased （the shank length was significantly increased in the third week, P〈0.05; the leg muscle weight was significantly improved by 3.87%, P〈 0.05）; the skeleton quality improved （the density of skeleton mineralization was significantly increased by 6.11%, P 〈 0.01; serum calcium, phosphorus, and alkaline phosphatase activity were all improved）; and the growth performance was improved （feed conversion ratio was improved by 1.4% averagely; the uniformity of body weight, the shank length, the inclined body length and body height were significantly improved） in broiler chicken.

The Chinese skeleton: insights into microstructure that help to explain the epidemiology of fracture

Osteoporotic fractures are a major public health problem worldwide, but incidence varies greatly across racial groups and geographic regions. Recent work suggests that the incidence of osteoporotic fracture is rising among Asian populations. Studies comparing areal bone mineral density and fracture across races generally indicate lower bone mineral density in Asian individuals including the Chinese, but this does not reflect their relatively low risk of non-vertebral fractures. In contrast, the Chinese have relatively high vertebral fracture rates similar to that of Caucasians. The paradoxically low risk for some types of fractures among the Chinese despite their low areal bone mineral density has been elucidated in part by recent advances in skeletal imaging. New techniques for assessing bone quality non-invasively demonstrate that the Chinese compensate for smaller bone size by differences in hip geometry and microstructural skeletal organization. Studies evaluating factors influencing racial differences in bone remodeling, as well as bone acquisition and loss, may further elucidate racial variation in bone microstructure. Advances in understanding the microstructure of the Chinese skeleton have not only helped to explain the epidemiology of fracture in the Chinese, but may also provide insight into the epidemiology of fracture in other races as well.

The Most Complete Pistosauroid Skeleton from the Triassic of Yunnan,China

A new specimen discovered from the Falang Formation in northeastern Yunnan represents the most complete skeleton of Triassic pistosauroids. The new specimen is referred to Yunguisaurus Cheng et al., 2006 on the basis of the skull features, such as the presence of a separated nasal entering the external naris, a large pineal foramen located at the frontal/parietal suture and an interpterygoid vacuity with a narrow anterior extension. The new specimen differs from the type species of Yunguisaurus liae Cheng et al., 2006 in some aspects. Most of these differences can be attributed to ontogenetic variations. The new specimen is provisionally considered as Yunguisaurus cf. liae although its relatively short snout of the skull and slenderer hyoid may not be explained ontogenetically. Whether or not the new specimen represents a different taxon has to wait for a detailed study of the whole skeleton.

A Stiffness Variable Passive Compliance Device with Reconfigurable Elastic Inner Skeleton and Origami Shell

Devices with variable stiffness are drawing more and more attention with the growing interests of human-robot interaction,wearable robotics,rehabilitation robotics,etc.In this paper,the authors report on the design,analysis and experiments of a stiffness variable passive compliant device whose structure is a combination of a reconfigurable elastic inner skeleton and an origami shell.The main concept of the reconfigurable skeleton is to have two elastic trapezoid four-bar linkages arranged in orthogonal.The stiffness variation generates from the passive deflection of the elastic limbs and is realized by actively switching the arrangement of the leaf springs and the passive joints in a fast,simple and straightforward manner.The kinetostatics and the compliance of the device are analyzed based on an efficient approach to the large deflection problem of the elastic links.A prototype is fabricated to conduct experiments for the assessment of the proposed concept.The results show that the prototype possesses relatively low stiffness under the compliant status and high stiffness under the stiff status with a status switching speed around 80 ms.

SALVIANOLIC ACID G,A CAFFEIC ACID DIMER WITH A NOVEL TETRACYCLIC SKELETON

Salvianolic acid G,a caffeic acid dimer with a novel tetracyclic skeleton was isolated from the roots of Salvia miltiorrhiza.Its structure was elucidated by chemical and spectral analysis,especially by 2D NMR analysis.