Skin and Soft Tissue Infections in the Surgical Area at the Kara Teaching Hospital

Objective: To report the management of skin and soft tissue infections in the surgical area of Kara University Hospital in Togo. Material and Methods: This study was conducted retrospectively from January 1, 2021, to December 31, 2022, in the general surgery and orthopedic trauma departments. The study focused on soft tissue infections of the pelvic and thoracic limbs and analyzed epidemiological, clinical, paraclinical, therapeutic, and evolutionary data. Results: We registered 165 patients, comprising 109 men and 56 women.The sex ratio (F/H) were 0.51. The mean age was 45 years with extremes ranging from 23 to 90 years. Farmers (64.8%) followed by housewives (34.0%) were the social strata most affected. The consultation period varied between 1 and 90 days. The pathologies found were necrotizing fasciitis (53.3%), erysipelas (18.2%), infected limb wounds (12.1%), pyomyositis (9.7%), and necrotizing dermo-hypodermitis (1.8%). The main procedures performed were necrosectomy and grafting (62.9%), sample necrosectomy (18.8%), drainage (9.7%), and pelvic limb amputation (1.2%). Follow-up was favorable in 86.7% of cases. The study noted a death rate of 13.3% due to septic shock secondary to a delay in consultation. Conclusion: Skin and soft tissue infections were a common reason for surgical hospitalization at Kara University Hospital, with a high mortality rate due to delayed consultations.

The clinical characteristics and risk factors for necrotizing soft tissue infection in children

Importance:Necrotizing soft tissue infection(NSTI)is a serious infectious disease.However,the early clinical manifestations and indicators of NSTI in children are still unclear.Objective:The purpose of this study was to analyze the clinical characteristics and risk factors of NSTI in pediatric patients.Methods:A total of 127 children with skin and soft tissue infection(SSTI)were treated at our hospital and divided into two groups:the NSTI group and the non-NSTI group,based on their discharge diagnosis from January 2011 to December 2022.Then,we collected and analyzed the clinical characteristics and risk factors of all patients,including sex and age,disease inducement,admission temperature,local skin manifestations,infection site,the presence of sepsis,bacterial culture,and laboratory indicators.Results:In our study,there was a statistical difference in the age distribution and disease inducement between NSTI and non-NSTI groups.The occurrence of local skin manifestations(blisters/bullae and ecchymosis)and the presence of sepsis significantly increased in the NSTI group compared to the non-NSTI group.Additionally,only the platelet count on laboratory tests was statistically different between the NSTI and non-NSTI groups.Finally,the logistic regression analysis suggested that local skin manifestations such as blisters/bullae,and ecchymosis,as well as the presence of sepsis,were identified as risk factors for NSTI.Interpretation:Children with SSTI and skin manifestations such as blisters/bullae,ecchymosis,and the presence of sepsis are at a higher risk of developing NSTI.These symptoms serve as useful indicators for early detection of NSTI.

Severe monobacterial necrotizing soft tissue infection by group A Streptococcus:A surgical emergency

Eight percent of necrotizing soft tissue infections(NSTI) are attributable to group A Streptococci(GAS),and among these,50%develop streptococcal toxic shock syndrome.The reported mortality associated with NSTI reaches 32%.We present cases of two healthy individuals with minor GAS skin infection which developed to a rapidly progressed NSTI and sepsis despite of the antibiotic treatment,aiming to discuss the lessons learned from the course and management of these patients.

Application of a pre-filled tissue expander for preventing soft tissue incarceration during tibial distraction osteogenesis

BACKGROUND Bone transport and distraction osteogenesis has been widely used to treat bone defects after traumatic surgery,but,skin and soft tissue incarceration can be as high as 27.6%.AIM To investigate the efficacy of inserting a tissue expander to prevent soft tissue incarceration.METHODS Between January 2016 and December 2018,12 patients underwent implantation of a tissue expander in the subcutaneous layer in the vicinity of a tibial defect to maintain the soft tissue in position.A certain amount of normal saline was injected into the tissue expander during surgery and was then gradually extracted to shrink the expander during the course of transport distraction osteogenesis.The tissue expander was removed when the two ends of the tibial defect were close enough.RESULTS In all 12 patients,the expanders remained intact in the subcutaneous layer of the bone defect area during the course of transport distraction osteogenesis.When bone transport was adequate,the expander was removed and the bone transport process was completed.During the whole process,there was no incarceration of skin and soft tissue in the bone defect area.Complications occurred in one patient,who experienced poor wound healing.CONCLUSION The pre-filled expander technique can effectively avoid soft tissue incarceration.The authors’primary success with this method indicates that it may be a valuable tool in the management of incarcerated soft tissue.

Effect of artificial dermis combined with jinfu ning on skin healing and bacterial detection rate of finger abdomen

Objective: To explore the effect of artificial dermis combined with rhGM-CSF(Jinfuning) on healing of soft tissue defect of finger ventral skin and the influence of bacterial detection rate. Methods: Totally 110 patients with finger injury admitted to the rehabilitation department of our department from January 2017 to June 2018 were collected and divided into control group and observation group according to the random number table method with 55 cases in each group. The control group received direct artificial derma lrepairing after thorough debridement, while the observation group received recombinant gm-csf gel coating on the wound surface before artificial dermal repairing, Wound healing, wound inflammation, bacterial detection rate, inflammatory factor expression, follow-up and adverse reactions were compared between the two groups. Results: The wound healing rate of the observation group at 7, 14, 21 and 28 days after treatment was significantly higher than that of the control group (t= 11.211, P =0.000).( T = 14.895, P =0.000;T = 25.346, P=0.000;T =8.247, P=0.000). The wound healing time of the observation group was (19.7±2.3) d, and that of the control group was (27.4±3.3) d. The average wound healing time of the observation group was significantly shorter than that of the control group, and the difference was statistically significant (t=14.197, P= 0.000). Observation group wound inflammation at each time point score was significantly lower than the control group, the group rooms, time points, ·point interaction effect between the comparison, the differences were statistically significant (P <0.05), the observation group wound bacteria detection rate of 7.27% (4 cases) : the control bacteria detection rate was 21.81% (12 cases), difference was statistically significant (chi-square = 4.68, P= 0.0305), the observation group of bacteria detection rate was significantly lower than the control group;The bacteria detected in the two groups were mainly e. coli, tetanus bacillus and fungi. There was no significant difference in the indicators between the two groups before treatment, and the values of inflammatory cytokines il-1 and TNF- IOD in the two groups were significantly decreased after treatment, and the observation group was significantly lower than the control group, with statistically significant differences (P < 0.05). No serious adverse reactions occurred in either group during the treatment. Conclusion: the application of artificial dermals combined with jinfuning can promote wound healing of skin and soft tissue defect of finger abdomen, effectively inhibit bacterial infection of wound surface, reduce inflammation and infection,reducing bacterial detection rate.

Molecular Epidemiology of Staphylococcus aureus among Patients with Skin and Soft Tissue Infections in Two Chinese Hospitals

Background：Staphylococcus aureus is one of the predominant causes of skin and soft tissue infections （SSTIs）,but limited data were available regarding the characterization of S.aureus from SSTIs patients in Jiangsu Province in China.We aimed to investigate the molecular epidemiology ofS.aureus among SSTIs patients in two hospitals of Jiangsu Province.Methods：Sixty-two patients with SSTIs from two Chinese hospitals in Jiangsu Province were enrolled in this study,and 62 S.aureus isolates were collected from February 2014 to January 2015.S.aureus isolates were characterized by antimicrobial susceptibility testing,toxin gene detection,and molecular typing with sequence type,Staphylococcus protein A gene type,accessorygeneregulator（agr）group,and Staphylococcal cassette chromosome mec type.Results：Sixteen （25.8%） methicillin-resistant S.aureus （MRSA） isolates were detected,and there was no isolate found resistant to vancomycin,teicoplanin,sulfamethoxazole-trimethoprim,and linezolid.The sei was the toxin gene most frequently found,and no lukS/F-PV-positive isolates were detected among the SSTIs＆#39; patients.Molecular analysis revealed that ST398 （10/62,16.1%;2 MRSA and 8 methicillin-susceptible S.aureus） to be the dominant clone,followed by ST5 （8/62,12.9%） and ST7 （8/62,12.9%）.Conclusions：The livestock ST398 was the most common clone among patients with S.aureus SSTIs in Jiangsu Province,China.Surveillance and further studies on the important livestock ST398 clone in human infections are necessarily requested.

Risk stratification system for skin and soft tissue infections after allogeneic hematopoietic stem cell transplantation:PAH risk score

Skin and soft tissue infections(SSTIs)refer to infections involving the skin,subcutaneous tissue,fascia,and muscle.In transplant populations with hematological malignancies,an immunocompromised status and the routine use of immunosuppressants increase the risk of SSTIs greatly.However,to date,the profiles and clinical outcomes of SSTIs in hematopoietic stem cell transplantation(HSCT)patients remain unclear.This study included 228 patients(3.67%)who developed SSTIs within 180 days after allogeneic HSCT from January 2004 to December 2019 in Peking University People’s Hospital.The overall annual survival rate was 71.5%.We compared the differences between survivors and non-survivors a year after transplant and found that primary platelet graft failure(PPGF),comorbidities of acute kidney injury(AKI),and hospital-acquired pneumonia(HAP)were independent risk factors for death in the study population.A PPGF-AKI-HAP risk stratification system was established with a mortality risk score of 1×PPGF+1×AKI+1×HAP.The areas under the curves of internal and external validation were 0.833(95%CI 0.760–0.906)and 0.826(95%CI 0.715–0.937),respectively.The calibration plot revealed the high consistency of the estimated risks,and decision curve analysis showed considerable net benefits for patients.

胸背动脉穿支皮瓣在肩胸背部创面修复中的临床应用

目的探讨胸背动脉穿支皮瓣在肩胸背部皮肤软组织缺损修复中的应用。方法自2019年1月至2022年12月,应用胸背动脉穿支皮瓣修复肩胸背部皮肤软组织缺损8例,致伤原因均为肿瘤切除术后。术前应用CTA和手持多普勒超声确认胸背动脉的存在、走行、分支及穿支位置。根据创面位置、面积设计胸背动脉穿支皮瓣。皮瓣仅携带穿支发出位置的极少量肌肉,将胸背动脉降支近端从肌肉内剥离,保留胸背动脉横支和胸背神经。如血管蒂长度不足,可切断横支。皮瓣带蒂转移修复创面。供瓣区拉拢缝合。结果8例皮瓣均存活,供瓣区切口愈合好。随访6个月到2年,所有患者受区外观满意,供瓣区无明显畸形,肩关节功能无明显影响。结论胸背动脉穿支皮瓣血供可靠,血管蒂长,且基本完整地保留了背阔肌功能,是修复肩胸背部邻近创面的良好选择。

股前外侧穿支皮瓣的个性化精准设计:十年1079例临床疗效分析

目的探讨个性化精准设计的股前外侧穿支皮瓣重建各种复杂组织缺损的临床疗效。方法回顾分析我科2013年1月-2023年1月采用个性化精准设计的各种股前外侧穿支皮瓣修复的1079例患者的临床疗效。以旋股外侧动脉降支为血管蒂切取1013例(其中小儿65例)、横支为血管蒂切取40例、斜支为血管蒂切取26例(小儿1例),以旋股内侧动脉或股动脉来源穿支为蒂切取9例。其中传统股前外侧穿支皮瓣游离移植441例、带蒂转移27例、特殊形式穿支皮瓣基本术式511例、衍生术式100例。修复下肢787例,上肢264例,躯干部17例,头颈部4例,上述多部位7例。并对各种个性化精准设计的股前外侧穿支皮瓣术后临床疗效及并发症发生率进行统计比较。结果本组1079例股前外侧穿支皮瓣中,术后顺利成活1063例,其中发生血管危象行探查术成活14例,总成功率为98.52%。比较游离股前外侧穿支皮瓣、带蒂转移、特殊形式穿支皮瓣基本术式和衍生术式各组成功率,结果显示各组间成功率无明显差异(P>0.05)。本组1079例股前外侧穿支皮瓣主要并发症发生情况:静脉危象35例(3.24%),动脉危象22例(2.04%),感染19例(1.76%),切口延迟愈合6例(0.56%),完全坏死16例(1.48%),部分坏死35例(3.24%)。统计学分析显示静脉危象方面特殊形式穿支皮瓣基本类型组发生率低于衍生术式组(P<0.001),切口感染方面带蒂转移组发生率高于特殊形式穿支皮瓣组(P=0.007),切口延迟愈合方面传统游离移植组发生率高于特殊形式穿支皮瓣组(P=0.04),皮瓣部分坏死方面带蒂转移组发生率高于特殊形式穿支皮瓣组(P=0.008)。结论股前外侧穿支皮瓣个性化精准设计,可以获得良好的临床疗效,值得临床推广应用。

肝硬化失代偿期患者皮肤感染致脓毒性休克的护理

总结1例肝硬化失代偿期患者皮肤软组织非特异性感染致脓毒性休克的护理体会。护理要点:以目标平均动脉压为导向,实施液体复苏;加强全程营养管理,加速创面修复;肝硬化失代偿期间,出血与血栓防范护理;加强院感管理,预防院内感染。经过45 d个性化的治疗和护理,双下肢植皮存活,无院内感染发生,患者康复出院。

游离背阔肌双叶皮瓣修复肢体软组织缺损的效果

目的探讨游离背阔肌双叶皮瓣修复肢体软组织缺损的效果。方法采用游离背阔肌双叶皮瓣修复9例肢体严重创伤患者,胸背动脉外侧分支背阔肌皮瓣切取范围为13.5 cm×6.5 cm~23.5 cm×9.0 cm,胸背动脉内侧分支背阔肌皮瓣切取范围为6.5 cm×5.5 cm~10.5 cm×7.5 cm。皮瓣切取后进行适当调整以修复各种不规则的缺损创面,皮瓣供区创面可直接缝合或仅需少量皮片移植修复。结果患者均获得随访,时间6~23个月。术后8例游离背阔肌双叶皮瓣全部成活,1例胸背动脉内侧支背阔肌皮瓣远端少部分坏死,经二期切除缺损创面直接缝合后愈合。7例因皮瓣臃肿行皮瓣修薄术,2例无需二次修整。末次随访时9例皮瓣质地及外形均良好,创伤肢体活动功能均恢复满意。7例供区直接缝合,遗留线状瘢痕,2例供区少量皮片移植修复。结论背阔肌皮瓣解剖恒定,血运可靠,供区隐蔽,切取面积范围大,是修复肢体严重创伤大面积软组织缺损的良好方法,而且采取双叶切取既有利于供区创面直接缝合,又有利于不规则创面的修复。

改良腓动脉穿支螺旋桨皮瓣在足踝部皮肤软组织缺损中的修复效果

目的:探讨足踝部皮肤软组织缺损患者采用改良腓动脉穿支螺旋桨皮瓣修复的效果。方法:选择2019年7月—2022年12月贵州省人民医院整形烧伤外科收治的100例足踝部皮肤软组织缺损行皮瓣修复的患者。按照随机数表法分为对照组和观察组,各50例,对照组予以腓动脉穿支皮瓣修复,观察组予以改良腓动脉穿支螺旋桨皮瓣修复。观察两组皮瓣情况(皮瓣一期成活率、增生性瘢痕、色素沉着发生率)、皮瓣感觉功能、踝关节活动度(踝关节跖屈、背伸角度)及踝关节功能[美国足踝外科协会(AOFAS)踝与后足评分系统评分]。结果:观察组皮瓣一期成活率为94.00%,高于对照组的80.00%,差异有统计学意义(P<0.05);两组术后增生性瘢痕、色素沉着发生率比较,差异无统计学意义(P>0.05)。观察组皮瓣感觉恢复优良率为88.00%,高于对照组的72.00%,差异有统计学意义(P<0.05)。术后6个月,两组踝关节跖屈、背伸角度高于术前,且观察组高于对照组,差异有统计学意义(P<0.05)。术后6个月,两组疼痛、力线及功能维度评分高于术前,且观察组高于对照组,差异有统计学意义(P<0.05)。结论:改良腓动脉穿支螺旋桨皮瓣在足踝部皮肤软组织缺损修复中血运可靠,能改善踝关节功能,促进皮瓣感觉功能恢复,提高皮瓣一期成活率。

基于Langer线的穿刺体位对肿瘤化疗患者输液港难免性医用黏胶相关皮肤损伤的预防效果研究

目的探究基于Langer线的无损伤针穿刺体位对肿瘤化疗患者输液港难免性黏胶相关皮肤损伤的预防效果。方法通过平行胸部Langer线对床头抬高60~90°和平卧位穿刺进行皮肤软组织力学、表皮屏障功能理论分析,然后选取2019年5月至2020年5月南京医科大学第一附属医院肿瘤科79例植入胸壁输液港、既往应用Ⅳ3000及液体敷料皮肤保护性屏障仍出现输液港黏胶相关性皮肤损伤的患者为研究对象。采用前瞻性自身前后对照,干预前采用平卧位穿刺,干预后床头抬高60~90°穿刺,比较两种穿刺体位对输液港黏胶相关性皮肤损伤预防效果和带针期间舒适度的影响。结果干预后患者输液港黏胶相关性皮肤相关性损伤总发生率较干预前显著降低(P<0.001),机械性损伤发生率、接触性皮炎发生率较干预前显著降低(均P<0.05),输液港带针期间舒适度较干预前明显提高(P<0.001),且不增加患者穿刺时的疼痛感(P=0.692)。结论床头抬高60~90°穿刺可降低肿瘤化疗患者输液港难免性黏胶相关皮肤损伤,提高患者带针期间的舒适度。

外耳再造耳后皮肤软组织扩张器植入后并发症现状及危险因素分析

目的探讨外耳再造耳后皮肤软组织扩张器植入后并发症现状及危险因素,为临床干预措施的制定提供参考。方法对2020年1月至2023年3月在我院接受耳后皮肤软组织扩张器植入的151例(163耳)外耳再造患者临床资料进行回顾性分析,了解其并发症发生现状;根据耳后皮肤软组织扩张器植入后是否发生并发症,将其分为并发症组和无并发症组,并运用多因素Logistic回归分析外耳再造耳后皮肤软组织扩张器植入后并发症的危险因素。结果本研究163耳有37耳发生并发症,并发症总发生率为22.69%,其中血肿18例,占总并发症的48.65%,感染10耳,占比27.03%,切口裂开4耳,占比10.81%,扩张器外漏3耳,占比8.11%,扩张器不张1耳,占比2.70%,皮瓣坏死1耳,占比2.70%;并发症发生平均时间为扩张器植入后(6.82±1.65)天。单因素分析结果显示,并发症组和无并发症组在年龄、居住地、引流管放置方式、扩张器容量、注水速度等方面存在组间差异,具有统计学意义(P﹤0.05);多因素Logistic回归分析显示,居住在农村(OR=2.079,95%CI:1.166~3.707,P=0.013)、引流管平位放置(OR=1.898,95%CI::0.962~3.748,P=0.065)、扩张器容量﹥100ml(OR=2.092,95%CI:1.128~3.878,P=0.019)、注水速度每周≥3次(OR=1.962,95%CI:1.049~3.667,P=0.035)是耳后皮肤软组织扩张器植入后并发症发生的危险因素。结论外耳再造耳后皮肤软组织扩张器植入后并发症发生率较高,居住在农村、引流管平位放置、扩张器容量>100 ml、注水速度每周≥3次是并发症发生的危险因素,临床应根据患者实际情况选择合适的引流方式、扩张器容量,并实施科学的注射速度,以降低并发症发生率,为外耳再造提供充足皮瓣。

顺行和逆行岛状皮瓣在手指末节离断伤后皮肤软组织缺损修复中的临床疗效对比

目的对比顺行和逆行岛状皮瓣在手指末节离断伤后皮肤软组织缺损修复中的临床疗效。方法选取南京市江宁医院2021年4月—2023年4月收治的80例手指末节离断伤患者为研究对象,以红蓝球抽签方式将其随机分为对照组(n=40)及观察组(n=40)。对照组采用指动脉逆行岛状皮瓣修复术治疗,观察组采用指动脉顺行岛状皮瓣修复术治疗。比较两组患者的临床疗效、伤指活动度、伤指血液循环、伤指恢复情况及围手术期并发症发生率。结果观察组的临床治疗有效率为97.50%,高于对照组的85.00%,差异有统计学意义(P<0.05)。观察组的两点辨别觉低于对照组,远侧指间关节活动度大于对照组,指甲长度长于对照组,组间差异有统计学意义(P<0.05)。观察组的血液循环优良率为100.00%,高于对照组的90.00%,差异有统计学意义(P<0.05)。观察组的伤指感觉恢复评分高于对照组,差异有统计学意义(P<0.05)。观察组的并发症发生率为7.50%,低于对照组的25.00%,差异有统计学意义(P<0.05)。观察组的手术时间及创面愈合时间均短于对照组,组间差异有统计学意义(P<0.05)。结论指动脉逆行与顺行岛状皮瓣修复手术的一般情况均较优,但指动脉顺行岛状皮瓣修复术在手指末节离断伤后皮肤软组织缺损修复方面的效果更佳,能更好地促进患者伤指活动及血液循环的恢复,手术时间及术后创面愈合时间均更短,综合疗效更佳,值得临床推广使用。

腹膜透析导管出口周围疖肿的发生情况及影响因素分析

目的探讨腹膜透析(peritoneal dialysis,PD)导管出口周围疖肿的发生情况及影响因素。方法选择2011年9月─2017年9月北京大学人民医院肾内科规律随访的PD患者,回顾其PD导管出口周围疖肿的发生情况及临床资料,分析其相关影响因素。结果183名PD患者入选研究,男性88例(占48.1%),平均年龄(59.8±13.8)岁,透析龄27(15,51)月。其中23名(12.6%)患者发生36例次出口周围疖肿,发生率0.05次/风险年。14例次(占38.9%)患者疖肿发生部位以PD导管为中心、周围6~9点的位置。并发症方面:4例次(占11.1%)疖肿合并出口和/或隧道感染,无合并腹膜炎。Logistic回归分析结果显示:透析龄(OR=0.969,95%CI:0.941~0.998,P=0.039)、合并糖尿病(OR=3.014,95%CI:1.050~8.651,P=0.040)、血C反应蛋白(OR=1.154,95%CI:1.065~1.251,P<0.001)是PD患者出口周围发生疖肿的独立危险因素。通过Logistic回归分析PD患者出口疖肿频发的相关因素,结果显示合并糖尿病(OR=5.513,95%CI:1.029~29.536,P=0.046)、C反应蛋白(OR=1.103,95%CI:1.016~1.197,P=0.019)是出口周围疖肿频发的独立危险因素。结论PD导管出口周围疖肿形成在PD患者中并不少见,可能发展为出口感染和/或隧道感染。对合并糖尿病、透析龄较短、C反应蛋白水平高的患者应重点关注出口周围疖肿的发生,并给予相应的预防宣教,从而预防出口和/或隧道感染。

拇指尺背侧皮神经营养血管皮瓣修复拇指C形缺损

目的:探讨拇指尺背侧皮神经营养血管皮瓣修复拇指C形缺损的方法及临床效果。方法:2017年12月-2021年7月,笔者科室采用拇指尺背侧皮神经营养血管皮瓣修复拇指C形缺损患者6例,缺损面积为1.6 cm×2.8 cm~3.5 cm×4.5 cm,缺损范围均大于拇指周径的1/2,不超过3/4,皮瓣切取面积为2.0 cm×3.2 cm~4.0 cm×5.0 cm,供区移植全厚皮片。术后通过电话、微信和门诊随访皮瓣外观、感觉及手功能。结果:术后随访时间为3~26个月,平均9.4个月,所有皮瓣全部存活,供、受区均未发生感染,皮瓣外观良好,两点分辨觉8~22 mm。供区植皮均成活良好,2例供区愈合后遗留线性瘢痕。手指功能:优4例,良1例,可1例。结论:拇指尺背侧皮神经营养血管皮瓣修复拇指C形缺损,手术操作简单,成活率高,不损伤主要血管,术后疗效满意。

巴克无菌敷贴修复手指皮肤软组织缺损

目的探讨巴克无菌敷贴修复手指皮肤软组织缺损的临床疗效。方法对2016年12月-2020年12月收治的31例手指皮肤软组织缺损患者,使用巴克无菌敷贴进行局部换药处理,每天换药1~2次,直至创面愈合。观察创面愈合情况、创面愈合后的皮肤色泽及质地、感觉恢复情况及手部功能情况。结果31例创面全部愈合良好,愈合时间为14~75 d,平均21 d。术后随访平均8(6~24)个月,创面愈合后皮肤色泽分级:显效27例,有效4例;皮肤质地分级:显效25例,有效5例,无效1例;两点辨别觉5~7 mm;伤指功能恢复优27例,良2例,可2例,优良率93.5%。无反复破溃,无明显瘢痕增生和挛缩畸形病例。结论巴克无菌敷贴能有效修复手指皮肤软组织缺损,恢复良好手指外形和功能。

拇指桡背侧皮神经营养血管皮瓣瓦合邻指皮瓣修复拇指末节脱套样软组织缺损

目的:探讨拇指桡背侧皮神经营养血管皮瓣与示指背邻指皮瓣瓦合修复拇指末节脱套样软组织缺损的临床治疗效果。方法:2017年10月-2021年2月,笔者医院对12例拇指末节脱套样软组织缺损患者采用拇指桡背侧皮神经营养血管皮瓣与示指背邻指皮瓣瓦合修复,创面面积2.0 cm×5.5 cm~3.5 cm×7.5 cm,门诊随访皮瓣外观与感觉、手功能及术后并发症情况。结果:拇指桡背侧皮神经营养血管皮瓣切取范围为2.0 cm×2.0 cm~3.5 cm×4.0 cm,示指近节背侧邻指皮瓣切取范围为1.5 cm×2.0 cm~3.0 cm×3.5 cm。术后随访6~18个月,平均9.4个月,11例拇指桡背侧皮神经营养血管皮瓣及10例邻指皮瓣成活良好,伤口甲级愈合。远期随访,10例拇指指腹饱满,外观满意,2例拇指指尖皮瓣萎缩。12例皮瓣供区均愈合良好,无明显瘢痕增生,功能恢复良好。12例拇指恢复良好的对捏及对掌功能,拇指指腹两点感觉辨别试验为7~16 mm,指背两点感觉辨别试验为6~11 mm。评定手功能:优8例,良2例,中2例。结论:拇指桡背侧皮神经营养血管皮瓣与示指背邻指皮瓣瓦合修复拇指末节脱套样软组织缺损,手术操作简便、安全,临床效果好,值得在基层医院推广。

重庆某院皮肤科皮肤和软组织感染病原菌流行特征分析

目的了解皮肤科门诊及住院皮肤和软组织感染患者病原菌分布情况,并探讨其耐药性。方法采用回顾性分析的方法,对皮肤科2019年1月至2022年12月皮肤和软组织感染患者病原菌分布及药敏结果进行统计分析。菌株鉴定和药敏试验采用美国碧迪公司Phoenix-100 system全自动微生物鉴定/药敏系统及其配套的鉴定及药敏卡,按照美国临床实验室标准化协会(Clinical and laboratory standards institute,CLSI)M100-S31标准进行判定。采用Whonet 5.6软件进行数据的分析。结果共分离出1534株细菌;其中革兰阳性菌和革兰阴性菌分别占71.90及28.10%;耐甲氧西林金黄色葡萄球菌(Methicillin-resistant Staphylococcus aureus,MRSA)检出率为17.27%;碳青霉烯类耐药铜绿假单胞菌检出率为5.52%;大肠埃希菌及肺炎克雷伯菌的超广谱β-内酰胺酶(Extended spectrum beta-lactamases,ESBLs)检出率分别为64.4%、45.5%。结论皮肤和软组织感染的主要致病菌为金黄色葡萄球菌,临床医师在治疗此类感染时应充分结合药敏试验结果,合理用药。