Natural killer (NK) cell is a type of immune cell and is known to be particularly responsible for innate immunity such as anti-cancer immunity, defense mechanisms against infections, and secretion of various cytokines...Natural killer (NK) cell is a type of immune cell and is known to be particularly responsible for innate immunity such as anti-cancer immunity, defense mechanisms against infections, and secretion of various cytokines and chemokines for increasing recruitment of other immune cells. In this study, we investigated the potentials of NK-enriched lymphocytes (NKEL) conditioned media (CM) on skin care for cosmeceutical compositions. Various cytokines of NKEL CM can improve wound healing through epithelial-mesenchymal transition (EMT) by increasing KLKs (kallikreins) and reduce metalloproteinase (MMP)-1 and MMP-2 to inhibit wrinkle formation. Our results suggest that NKEL CM which has various cytokines promotes up-regulation of cell migration and KLKs and down-regulation of MMP-1 and MMP-2 by stimulating HaCaT keratinocytes migration. Therefore, NKEL CM can be used as a cosmetic composition that can play a role in skin regeneration and anti-aging.展开更多
近年来护肤保健整理已成为国际市场织物后整理的一种流行趋势。将自制的护肤整理剂角鲨烷微胶囊用于织物整理,考察了整理方式、黏合剂及整理剂用量、焙烘温度及时间等因素对织物上角鲨烷含量的影响。结果表明,以SCJ939为黏合剂,采用浸...近年来护肤保健整理已成为国际市场织物后整理的一种流行趋势。将自制的护肤整理剂角鲨烷微胶囊用于织物整理,考察了整理方式、黏合剂及整理剂用量、焙烘温度及时间等因素对织物上角鲨烷含量的影响。结果表明,以SCJ939为黏合剂,采用浸渍整理方式可获得比浸轧法更好的效果。通过正交试验优化的最佳整理工艺参数为:黏合剂质量浓度40 g/L,微胶囊整理剂质量浓度50 g/L,焙烘温度100℃,焙烘时间3 m in。在此工艺条件下,制备的织物上角鲨烷的含量约为1.2%。水洗20次后,织物上角鲨烷的含量仍能保持原有量的30%-40%。展开更多
文摘Natural killer (NK) cell is a type of immune cell and is known to be particularly responsible for innate immunity such as anti-cancer immunity, defense mechanisms against infections, and secretion of various cytokines and chemokines for increasing recruitment of other immune cells. In this study, we investigated the potentials of NK-enriched lymphocytes (NKEL) conditioned media (CM) on skin care for cosmeceutical compositions. Various cytokines of NKEL CM can improve wound healing through epithelial-mesenchymal transition (EMT) by increasing KLKs (kallikreins) and reduce metalloproteinase (MMP)-1 and MMP-2 to inhibit wrinkle formation. Our results suggest that NKEL CM which has various cytokines promotes up-regulation of cell migration and KLKs and down-regulation of MMP-1 and MMP-2 by stimulating HaCaT keratinocytes migration. Therefore, NKEL CM can be used as a cosmetic composition that can play a role in skin regeneration and anti-aging.
文摘近年来护肤保健整理已成为国际市场织物后整理的一种流行趋势。将自制的护肤整理剂角鲨烷微胶囊用于织物整理,考察了整理方式、黏合剂及整理剂用量、焙烘温度及时间等因素对织物上角鲨烷含量的影响。结果表明,以SCJ939为黏合剂,采用浸渍整理方式可获得比浸轧法更好的效果。通过正交试验优化的最佳整理工艺参数为:黏合剂质量浓度40 g/L,微胶囊整理剂质量浓度50 g/L,焙烘温度100℃,焙烘时间3 m in。在此工艺条件下,制备的织物上角鲨烷的含量约为1.2%。水洗20次后,织物上角鲨烷的含量仍能保持原有量的30%-40%。