Objective Although sleep is one of the most important health-related behavioral factors, the association between night sleep duration and cognitive impairment has not been fully understood. A cross-sectional study was...Objective Although sleep is one of the most important health-related behavioral factors, the association between night sleep duration and cognitive impairment has not been fully understood. A cross-sectional study was conducted with a random sample of 2,514 participants （≥ 40 years of age; 46.6% women） in China to examine the association between night sleep duration and cognitive impairment. Methods Night sleep duration was categorized as ≤ 5, 6, 7, 8, or ≥ 9 h per night. Cognitive function was measured using the Mini-Mental State Examination. A multivariate regression analysis was used to analyze the association of night sleep duration with cognitive impairment. A total of 122 participants were diagnosed with cognitive impairment. Results A U-shaped association between night sleep duration and cognitive impairment was found. The odds ratios （95% confidence intervals） of cognitive impairment （with 7 h of daily sleep being considered as the reference） for individuals reporting ≤ 5, 6, 8, and ≥ 9 h were 2.14 （1.20-3.83）, 1.13 （0.67-1.89）, 1.51 （0.82-2.79）, and 5.37 （1.62-17.80）, respectively （P ≤ 0.01）. Conclusion Short or long night sleep duration was an important sleep-related factor independently associated with cognitive impairment and may be a useful marker for increased risk of cognitive impairment.展开更多
In recent years,the ancient yin-yang theory has been gradually adopted by modern researchers,especially European and American scholars,and it has also been applied to modern scientific research on sleep,viruses,metabo...In recent years,the ancient yin-yang theory has been gradually adopted by modern researchers,especially European and American scholars,and it has also been applied to modern scientific research on sleep,viruses,metabolism,cancer,genes,autoimmune diseases,and so on.It is very promising and fruitful results have been reported.However,the understanding of the connotations of yin-yang theory is not sufficient and thorough enough in these studies.If we understand and apply yin-yang theory more comprehensively,it may provide us with additional potential mechanisms and research directions worthy of study.On the basis of promoting a comprehensive understanding of all three connotations of yin-yang theory,this review attempts to illustrate this theory,summarize its applications in modern scientific research,and reveal the potential research direction of modern medicine.展开更多
文摘Objective Although sleep is one of the most important health-related behavioral factors, the association between night sleep duration and cognitive impairment has not been fully understood. A cross-sectional study was conducted with a random sample of 2,514 participants （≥ 40 years of age; 46.6% women） in China to examine the association between night sleep duration and cognitive impairment. Methods Night sleep duration was categorized as ≤ 5, 6, 7, 8, or ≥ 9 h per night. Cognitive function was measured using the Mini-Mental State Examination. A multivariate regression analysis was used to analyze the association of night sleep duration with cognitive impairment. A total of 122 participants were diagnosed with cognitive impairment. Results A U-shaped association between night sleep duration and cognitive impairment was found. The odds ratios （95% confidence intervals） of cognitive impairment （with 7 h of daily sleep being considered as the reference） for individuals reporting ≤ 5, 6, 8, and ≥ 9 h were 2.14 （1.20-3.83）, 1.13 （0.67-1.89）, 1.51 （0.82-2.79）, and 5.37 （1.62-17.80）, respectively （P ≤ 0.01）. Conclusion Short or long night sleep duration was an important sleep-related factor independently associated with cognitive impairment and may be a useful marker for increased risk of cognitive impairment.
基金Supported by the National Key R&D Program of China(No.2020YFC2003100,No.2020YFC2003103)。
文摘In recent years,the ancient yin-yang theory has been gradually adopted by modern researchers,especially European and American scholars,and it has also been applied to modern scientific research on sleep,viruses,metabolism,cancer,genes,autoimmune diseases,and so on.It is very promising and fruitful results have been reported.However,the understanding of the connotations of yin-yang theory is not sufficient and thorough enough in these studies.If we understand and apply yin-yang theory more comprehensively,it may provide us with additional potential mechanisms and research directions worthy of study.On the basis of promoting a comprehensive understanding of all three connotations of yin-yang theory,this review attempts to illustrate this theory,summarize its applications in modern scientific research,and reveal the potential research direction of modern medicine.
