Newborns' sleep-wake cycle development on amplitude integrated electroencephalography

Background:To observe the development of neonatal sleep among healthy infants of different conceptional age(CA)by analyzing the amplitude-integrated electroencephalography(aEEG)of their sleep-wake cycles(SWC).Methods:Bedside aEEG monitoring was carried out for healthy newborns from 32 to 46 weeks CA between September 1,2011 and August 30,2012.For each aEEG tracing,mean duration of every complete SWC,number of SWC repetition within 12 hours,mean duration of each narrow and broadband of SWC,mean voltage of the upper edge and lower edge of SWC,mean bandwidth of SWC were counted and calculated.Analysis of the correlations between voltages or bandwidth of SWC and CA was performed to assess the developmental changes of central nervous system of newborns with different CA.Results:The SWC of different CA on aEEG showed clearly identifiable trend after 32 weeks of CA.The occurrence of SWC gradually increases from preterm to post-term infants;term infants had longer SWC duration.The voltage of upper edge of the broadband decreased at 39 weeks,while the lower edge voltage increases and the bandwidth of broadband declined along with the growing CA.The upper edge of the narrowband dropped while the lower edge rised gradually,especially in preterm stage.The width of the narrowband narrowed down while CA increased.Conclusions:The SWC on aEEG of 32-46 weeks infants showed a continuous,dynamic and developmental progress.The appearance of SWC and the narrowing bandwidth of narrowband is the main indicator to identify the CA-dependent SWC from the preterm to the late preterm period.The lower edge of the broadband identifi es the term to post-term period.

波幅整合脑电图在高胆红素血症新生儿睡眠觉醒周期监测中的应用

目的：通过波幅整合脑电图（aEEG）长程监测高胆红素水平对足月新生儿睡眠-觉醒周期（SWC）数量的影响。方法：aEEG监测203例高胆红素血症新生儿12h内SWC出现的数量，同时记录监测当日的血清总胆红素水平（TSB）。结果：在203例新生儿中，在正常SWC、SWC减少和无SWC3组之间TSB水平差异有统计学意义，TSB水平与SWC数量呈非线性负相关。红细胞葡萄糖-6-磷酸脱氢酶（G-6-PD）缺乏症为各组溶血的常见病因。结论：足月新生儿胆红素水平的增高与其SWC的数量减少之间呈非线性的关系。

波幅整合脑电图在高胆新生儿睡眠觉醒周期结构监测中的应用

目的通过波幅整合脑电图(a EEG)长程监测评估胆红素水平(TSB)、脑干听觉诱发电位(BAEP)及脑电图(EEG)异常程度对足月新生儿睡眠结构的影响。方法对159例高胆红素血症足月新生儿行12小时床边监测长程脑电图,计算a EEG上睡眠-觉醒周期(SWC)安静睡眠(QS)时间长度比例、收集当日的TSB、BAEP及EEG结果。结果在159例病人中,数据可视化结果显示随着胆红素水平的升高、EEG及BAEP异常程度的增加,QS期的比例逐渐减少。逐步广义线性模型结果证实胆红素水平及EEG异常是导致安静睡眠比例减少的主要因素,而BAEP异常程度则不显著。结论随着胆红素水平的增高及脑电图异常率的增加,足月新生儿睡眠-觉醒周期安静睡眠比例逐渐减少,SWC结构发生改变。

石羊河流域武威市水资源社会化循环评估

当前对水资源的合理开发利用和科学配置、建设节水型社会的对策,已从传统的水资源供给管理、技术性节水的阶段,发展到关注结构性节水和社会化管理的水需求管理阶段。虚拟水管理就是水资源社会化管理的一个典型例子。文中从社会经济系统对水资源的需求角度出发,应用水资源投入产出模型,通过量化经济部门对水资源需求的数量关联效应,对河西内陆河石羊河流域武威市区域的经济系统内各产业部门的虚拟水转移以及区域外输出进行测算,以为建立节水型社会体系、实现流域水资源综合管理、促进流域可持续发展提供参考依据。