This study aimed to explore the adsorption performance of sludge-based activated carbon(SBC)towards dissolved organic matters(DOMs)removal from sewage,and investigated the modification effect of different types of che...This study aimed to explore the adsorption performance of sludge-based activated carbon(SBC)towards dissolved organic matters(DOMs)removal from sewage,and investigated the modification effect of different types of chemicals on the structure of synthesized SBC.Waste activated sludge(WAS)was used as a carbon source,and HCl,HNO 3,and Na OH were used as different types of chemicals to modify the SBC.With the aid of chemical activation,the modified SBC showed higher adsorption performances on DOMs removal with maximum adsorption of 29.05 mg/g and second-order constant(k)of 0.1367(L/mol/sec)due to the surface elution of ash and minerals by chemicals.The surface elemental composition of MSBC suggested that the content of C-C and C-O functional groups on the surface of modified sludge-based activated carbon(MSBC)played an important role on the adsorption capacities of MSBC towards DOMs removal in sewage.Additionally,the residual molecular weight of DOMs in sewage was investigated using a 3-dimension fluorescence excitationemission matrix(3 D-EEM)and high-performance size exclusion chromatography(HP-SEC).Results showed that the chemical modification significantly improved the adsorption capacity of MSBC on humic acids(HA)and aromatic proteins(APN),and both of Na OH-MSBC and HCl-MSBC were effective for a wide range of different AMW DOMs removal from sewage,while the HNO 3-MSBC exhibited poorly on AMW organics of 2,617 Da and 409 Da due to the reducing content of macropore.In brief,this study provides reference values for the impact of the chemicals of the activation stage before the SBCs application.展开更多
Natural killer (NK) cell plays an important role in an innate immune response against viral infection. The kinetics regulation and functional consequences of NK cells in the pathogeneses of diseases are uncertain. We ...Natural killer (NK) cell plays an important role in an innate immune response against viral infection. The kinetics regulation and functional consequences of NK cells in the pathogeneses of diseases are uncertain. We analyzed NK cell distribution and function of successfully combination antiretroviral therapy (cART)-treated HIV-1 infected individuals in Khon Kaen Regional Hospital, Thailand. The results demonstrated that increased percentage and the total number of NK cell in cART-treated HIV-1 infected patients with preferential high levels of CD56dimCD16+ and CD56-CD16+ subsets when compared with a control group even in undetectable viral load (<40 copies per milliliter). Concomitantly, decreased cytotoxic activity measured by CD107asurface expression with maintained IFN-γ production implied the impairment of cytolytic activity was not recovered after cART treatment. Thus, altered NK cell frequency and function by HIV-1 infection are not completely recovered with cART, which may contribute to impaired cellular immune response and persistence of HIV-1.展开更多
This paper describes a system designed for linear servo cart systems that employs an integral-based Linear Active Disturbance Rejection Control(ILADRC)scheme to detect and respond to disturbances.The upgrade in this c...This paper describes a system designed for linear servo cart systems that employs an integral-based Linear Active Disturbance Rejection Control(ILADRC)scheme to detect and respond to disturbances.The upgrade in this control technique provides extensive immunity to uncertainties,attenuation,internal disturbances,and external sources of noise.The fundamental technology base of LADRC is Extended State Observer(ESO).LADRC,when combined with Integral action,becomes a hybrid control technique,namely ILADRC.Setpoint tracking is based on Bode’s Ideal Transfer Function(BITF)in this proposed ILADRC technique.This proves to be a very robust and appropriate pole placement scheme.The proposed LSC system has experimented with the hybrid ILADRC technique plotted the results.From the results,it is evident that the proposed ILADRC scheme enhances the robustness of the LSC system with remarkable disturbance rejection.Furthermore,the results of a linear quadratic regulator(LQR)and ILADRC schemes are comparatively analyzed.This analysis deduced the improved performance of ILADRC over the LQR control scheme.展开更多
基金the National Natural Science Foundation of China(Nos.51678546 and 41630318)the Chinese Universities Scientific Fund for Gradle plan of the China University of Geosciences(Wuhan)the National water pollution control and management technology major projects(Nos.2018ZX07105003 and 2018ZX 07110004)。
文摘This study aimed to explore the adsorption performance of sludge-based activated carbon(SBC)towards dissolved organic matters(DOMs)removal from sewage,and investigated the modification effect of different types of chemicals on the structure of synthesized SBC.Waste activated sludge(WAS)was used as a carbon source,and HCl,HNO 3,and Na OH were used as different types of chemicals to modify the SBC.With the aid of chemical activation,the modified SBC showed higher adsorption performances on DOMs removal with maximum adsorption of 29.05 mg/g and second-order constant(k)of 0.1367(L/mol/sec)due to the surface elution of ash and minerals by chemicals.The surface elemental composition of MSBC suggested that the content of C-C and C-O functional groups on the surface of modified sludge-based activated carbon(MSBC)played an important role on the adsorption capacities of MSBC towards DOMs removal in sewage.Additionally,the residual molecular weight of DOMs in sewage was investigated using a 3-dimension fluorescence excitationemission matrix(3 D-EEM)and high-performance size exclusion chromatography(HP-SEC).Results showed that the chemical modification significantly improved the adsorption capacity of MSBC on humic acids(HA)and aromatic proteins(APN),and both of Na OH-MSBC and HCl-MSBC were effective for a wide range of different AMW DOMs removal from sewage,while the HNO 3-MSBC exhibited poorly on AMW organics of 2,617 Da and 409 Da due to the reducing content of macropore.In brief,this study provides reference values for the impact of the chemicals of the activation stage before the SBCs application.
文摘Natural killer (NK) cell plays an important role in an innate immune response against viral infection. The kinetics regulation and functional consequences of NK cells in the pathogeneses of diseases are uncertain. We analyzed NK cell distribution and function of successfully combination antiretroviral therapy (cART)-treated HIV-1 infected individuals in Khon Kaen Regional Hospital, Thailand. The results demonstrated that increased percentage and the total number of NK cell in cART-treated HIV-1 infected patients with preferential high levels of CD56dimCD16+ and CD56-CD16+ subsets when compared with a control group even in undetectable viral load (<40 copies per milliliter). Concomitantly, decreased cytotoxic activity measured by CD107asurface expression with maintained IFN-γ production implied the impairment of cytolytic activity was not recovered after cART treatment. Thus, altered NK cell frequency and function by HIV-1 infection are not completely recovered with cART, which may contribute to impaired cellular immune response and persistence of HIV-1.
基金This research work was funded by Deputyship for Research&Innovation,Ministry of Education in Saudi Arabia under grant no(IFPRC-023-135-2020)。
文摘This paper describes a system designed for linear servo cart systems that employs an integral-based Linear Active Disturbance Rejection Control(ILADRC)scheme to detect and respond to disturbances.The upgrade in this control technique provides extensive immunity to uncertainties,attenuation,internal disturbances,and external sources of noise.The fundamental technology base of LADRC is Extended State Observer(ESO).LADRC,when combined with Integral action,becomes a hybrid control technique,namely ILADRC.Setpoint tracking is based on Bode’s Ideal Transfer Function(BITF)in this proposed ILADRC technique.This proves to be a very robust and appropriate pole placement scheme.The proposed LSC system has experimented with the hybrid ILADRC technique plotted the results.From the results,it is evident that the proposed ILADRC scheme enhances the robustness of the LSC system with remarkable disturbance rejection.Furthermore,the results of a linear quadratic regulator(LQR)and ILADRC schemes are comparatively analyzed.This analysis deduced the improved performance of ILADRC over the LQR control scheme.