The algorithm of autonomous orbit determination for the probe around small body is studied. In the algorithm, first, the observed images of the body are compared with its pre-computed model of the body to obtain the l...The algorithm of autonomous orbit determination for the probe around small body is studied. In the algorithm, first, the observed images of the body are compared with its pre-computed model of the body to obtain the location of the limb features of the body in the inertial coordinate. Second, the information of the images and features in utilized to obtain the position of the probe using the Levenberg-Marquardt algorithm. The position is then input to an extended Kalman filter which determines the real time orbit of the probe. Finally, considering the effective of the irregular small body shape perturbation and the small body model parameter error on the orbit determination precise, the procedure of autonomous orbit determination is validated using digital simulation.展开更多
Food safety is a major issue to public health and have attracted global attention.Fast,sensitive,and reliable detection methods for food hazardous substances is highly desirable.Aptamers which can bind to the target m...Food safety is a major issue to public health and have attracted global attention.Fast,sensitive,and reliable detection methods for food hazardous substances is highly desirable.Aptamers which can bind to the target molecules with high affinity and specificity represent an attractive tool for the recognition of food hazardous substances,which play an important role in the development and application of new food safety detection technology.But current assays for characterizing small molecule-aptamer binding are limited by either the mass sensitivity or the size differentiation ability.Herein,we proposed a comprehensive method for assessing the dissociation equilibria of small molecule-aptamer,which is immobilized-free under ambient conditions.The design employs the Le Chatelier’s principle and could be used to effectively measure small molecule-aptamer interactions.ATP binding aptamer and anti-aflatoxin B1 aptamer were used as the model system to determine their affinity,in which their dissociation equilibria measurements are in excellent close to their previous work.Due to the simplicity and sensitivity of this new method,we believe that it could be recommended as an effective tool for characterizing small molecule-aptamer interactions and promote the further application of small molecular aptamer in food safety.展开更多
Hydrazine,an essential chemical,has been used within a wide spectrum of industries,including pesticides,pharmaceuticals and even satellite-launching systems.However,the excessive consumption of hydrazine raised the ri...Hydrazine,an essential chemical,has been used within a wide spectrum of industries,including pesticides,pharmaceuticals and even satellite-launching systems.However,the excessive consumption of hydrazine raised the risk of environmental pollution accidents and occurrence of diseases because of its high toxicity and volatility.This led to the discovery of diverse fluorescent probes for the monitoring of the dangerous substance,including those based on organic small molecules and emerging nanomaterials.Herein,we are going to present a comprehensive review of recently reported hydrazine fluorescent probes,and discuss their structure design strategies and detection mechanisms.In particular,both organic small-molecule and nanomaterial fluorescent probes for hydrazine will be discussed together for the first time.展开更多
In order to examine the fundamental characteristics of corner separation in a decelerating cascade flow,the experimental apparatus was made and separations around a NACA65 blade in a decelerating channel flow were exa...In order to examine the fundamental characteristics of corner separation in a decelerating cascade flow,the experimental apparatus was made and separations around a NACA65 blade in a decelerating channel flow were examined.Two-dimensional calculations show that the NACA65 cascade flow that has 45 deg.of turning,1.24 of solidity and 17 deg.of stagger angle is equivalent to the channel flow that has 14 deg.of stagger angle in terms of pitchwise blade force.Experimental investigation by five-hole probe shows that the accumulations of low energy fluid can be seen around the corner part and the overturning flow due to the secondary flow exists.And,as the periodicity of the blade wake in a pitchwise direction is comparably good,the wake of this channel flow is similar to the wake of the cascade flow for two pitch portion.PIV measurement results shows that a vortex pattern can be seen in the momentary streamline on the suction surface of the blade and in the averaged streamline on the perpendicular to both the suction surface and the endwall.展开更多
基金This project was supported by the 15th Plan National Defence Science & Tehnology and Civil Space Previous Study Project.
文摘The algorithm of autonomous orbit determination for the probe around small body is studied. In the algorithm, first, the observed images of the body are compared with its pre-computed model of the body to obtain the location of the limb features of the body in the inertial coordinate. Second, the information of the images and features in utilized to obtain the position of the probe using the Levenberg-Marquardt algorithm. The position is then input to an extended Kalman filter which determines the real time orbit of the probe. Finally, considering the effective of the irregular small body shape perturbation and the small body model parameter error on the orbit determination precise, the procedure of autonomous orbit determination is validated using digital simulation.
基金supported by the National Key R&D Program of China(2017YFC1600603)the Funds for Huangshan Professorship of Hefei University of Technology(407-037019).
文摘Food safety is a major issue to public health and have attracted global attention.Fast,sensitive,and reliable detection methods for food hazardous substances is highly desirable.Aptamers which can bind to the target molecules with high affinity and specificity represent an attractive tool for the recognition of food hazardous substances,which play an important role in the development and application of new food safety detection technology.But current assays for characterizing small molecule-aptamer binding are limited by either the mass sensitivity or the size differentiation ability.Herein,we proposed a comprehensive method for assessing the dissociation equilibria of small molecule-aptamer,which is immobilized-free under ambient conditions.The design employs the Le Chatelier’s principle and could be used to effectively measure small molecule-aptamer interactions.ATP binding aptamer and anti-aflatoxin B1 aptamer were used as the model system to determine their affinity,in which their dissociation equilibria measurements are in excellent close to their previous work.Due to the simplicity and sensitivity of this new method,we believe that it could be recommended as an effective tool for characterizing small molecule-aptamer interactions and promote the further application of small molecular aptamer in food safety.
基金support from the National Natural Science Foundation of China(21977082 and 22037002)the Natural Science Basic Research Program of Shaanxi(2020JC-38).
文摘Hydrazine,an essential chemical,has been used within a wide spectrum of industries,including pesticides,pharmaceuticals and even satellite-launching systems.However,the excessive consumption of hydrazine raised the risk of environmental pollution accidents and occurrence of diseases because of its high toxicity and volatility.This led to the discovery of diverse fluorescent probes for the monitoring of the dangerous substance,including those based on organic small molecules and emerging nanomaterials.Herein,we are going to present a comprehensive review of recently reported hydrazine fluorescent probes,and discuss their structure design strategies and detection mechanisms.In particular,both organic small-molecule and nanomaterial fluorescent probes for hydrazine will be discussed together for the first time.
文摘In order to examine the fundamental characteristics of corner separation in a decelerating cascade flow,the experimental apparatus was made and separations around a NACA65 blade in a decelerating channel flow were examined.Two-dimensional calculations show that the NACA65 cascade flow that has 45 deg.of turning,1.24 of solidity and 17 deg.of stagger angle is equivalent to the channel flow that has 14 deg.of stagger angle in terms of pitchwise blade force.Experimental investigation by five-hole probe shows that the accumulations of low energy fluid can be seen around the corner part and the overturning flow due to the secondary flow exists.And,as the periodicity of the blade wake in a pitchwise direction is comparably good,the wake of this channel flow is similar to the wake of the cascade flow for two pitch portion.PIV measurement results shows that a vortex pattern can be seen in the momentary streamline on the suction surface of the blade and in the averaged streamline on the perpendicular to both the suction surface and the endwall.
