Existing problems of sewage treatment plants in small towns were summarized firstly,and then the developing trend of construction of sewage treatment plants in small towns was discussed from the aspects of project dec...Existing problems of sewage treatment plants in small towns were summarized firstly,and then the developing trend of construction of sewage treatment plants in small towns was discussed from the aspects of project decision,site selection,design,processing technology and construction financing models. Finally,outlooks for its future development were proposed to provide reference for the construction of sewage treatment plants in small towns in future.展开更多
Characteristic small cities and towns are the new vehicle for advancing new urbanization construction and supply-side reform.Zushan characteristic towns focus on tourism vacation,ecological livability,integration of p...Characteristic small cities and towns are the new vehicle for advancing new urbanization construction and supply-side reform.Zushan characteristic towns focus on tourism vacation,ecological livability,integration of production and cities,cultural heritage,poverty alleviation and other functions,and focus on building a new type of"product,city,and people"trinity,is a new benchmark for industrial transformation and upgrading.This article uses field surveys,interviews,and other methods to investigate the status quo of the construction of small towns with Zushan characteristics.Based on this,SWOT analysis of small towns is carried out,and the disadvantages and threats to its development are determined from the nature of towns and cities,infrastructure construction,and townships.Five suggestions were made for the construction of capital,the cultivation of special industries,and the detennination of the main body of urban construction.展开更多
Based on the five-year long dynamic tracking and investigation of the peasant households of the Lishu village, the influences by small town construction on the economy and employment of the original peasant households...Based on the five-year long dynamic tracking and investigation of the peasant households of the Lishu village, the influences by small town construction on the economy and employment of the original peasant households are discussed. On the one hand, small town construction plays a positive role in adjustment of the industrial structure of the original peasant households and in the transfer of their employment towards non-agricultural industries. On the other hand the economic growth of the original peasant households is not so well sustainable, and is so fluctuating. Moreover, the unbalance of income distribution of the said households has been furthered, and small town construction has made the existing labor surplus of the original peasant households more serious, particularly the women labor surplus.展开更多
This paper is to examine the urban and rural construction land data of Dafang between basic year and final year based on country scale and spatial econometrics,and analyze its spatial pattern and change feature. Accor...This paper is to examine the urban and rural construction land data of Dafang between basic year and final year based on country scale and spatial econometrics,and analyze its spatial pattern and change feature. According to the results,the construction lands in all the villages of Dafang County showed strong spatial autocorrelation and significant spatial cluster. After the analysis of local Moran's I,the construction lands in 381 villages of 36 counties presented strong activity. The original small-scale villages were gradually enlarging,which will not only gradually benefit local development,but also be in accordance with the strategy of " one city,one district,eight parks".展开更多
There are many papers on red tide occurrences and eutrophication. Here, we use these data to examine the relationship between dam construction and red tide occurrence in Kesennuma Bay, Dokai Bay and the small bays of ...There are many papers on red tide occurrences and eutrophication. Here, we use these data to examine the relationship between dam construction and red tide occurrence in Kesennuma Bay, Dokai Bay and the small bays of the Seto Inland Sea, Japan. Here, for the first time, differences in mechanisms of red tide occurrences in these small bays are demonstrated. Mud overflowing from dams likely induces red tides in these areas as the mud flows out from the mouth of the rivers, is carried along the coast by the longshore current, and then enters and is deposited into small bays. Red tide is considered to be induced by the accumulation of mud and siltation. From data on the locations and year of red tide occurrences in the Gulf of Mexico, the same mechanism as for the occurrence of red tide in small bays of Japanwas found to be applicable.展开更多
Objective As there is currently no clear recommendation for third-line chemotherapy for small cell lung cancer (SCLC), its efficacy is unknown. To date, there have rarely been reports of Chinese patients with SCLC w...Objective As there is currently no clear recommendation for third-line chemotherapy for small cell lung cancer (SCLC), its efficacy is unknown. To date, there have rarely been reports of Chinese patients with SCLC who received third-line chemotherapy. Therefore, we investigated the efficacy, safety, and prognostic factors of Chinese patients with SCLC treated with third-line chemotherapy. Methods A retrospective analysis of patients with SCLC who received third-line chemotherapy was performed. Results Between 2007 and 2013, 62 patients [62 men (75.6%), 20 women (24.4%); median age at the time of diagnosis, 55 years] received third-line chemotherapy at our center. Of these patients, 44 had limited-stage disease and 38 had extensive-stage disease. On third-line chemotherapy, 55 (67.1%) patients had an Eastern Cooperative Oncology Group performance status (ECOG PS) of 0-1, objective response rate of 15.9%, and median overall survival after third-line chemotherapy (OS-3) and median progres- sion-free survival after third-line chemotherapy (PFS-3) of 5.6 months and 3.0 months, respectively. On univariate analysis, PFS-3 was significantly related with ECOG PS (P = 0.005), response to second-line chemotherapy (P = 0.002), response to third-line chemotherapy (P 〈 0.001), and PFS after second-line chemotherapy (P = 0.026). OS-3 was significantly related with ECOG PS (P 〈 0.001), response to third-line chemotherapy (P = 0.033), PFS after first-line therapy (P = 0.044), and PFS after second-line therapy (PFS-2) (P = 0.007). On multivariate analysis, ECOG PS (P = 0.008) and response to third-line chemotherapy (P = 0.046) were independent prognostic factors for PFS-3, while ECOG PS (P = 0.007) and PFS-2 (P 〈 0.001) were independent prognostic factors for OS-3. Conclusion Few patients with SCLC receive third-line chemotherapy. Our findings suggest that patients with an ECOG PS 0-1 and PFS-2 for 〉3 months will be benefit from third-line chemotherapy, which should be actively offered to them.展开更多
In recent years, China has been frequented by floods and droughts which has greatly evoked much concern from the Central Government about rural water conservancy construction. Irrigation is closely related to the &quo...In recent years, China has been frequented by floods and droughts which has greatly evoked much concern from the Central Government about rural water conservancy construction. Irrigation is closely related to the "three rural" issues and concerns about the vital interests of farmers. To achieve a virtuous circle of agricultural water supply, it is necessary and urgent to establish Farmer Water User Association (FWUA) to participate in the construction, management and maintenance of small-scale irrigation system. Based on the survey on nationwide "Small-scale irrigation conditions", the roles of FWUA in the construction, management and maintenance of small-scale water conservancy have studied in this study.展开更多
The 12 th Five-Year Plan period was unusual five years in the development of China. Under the dual pressure of complex international environment and arduous domestic reform task,China made outstanding achievements in ...The 12 th Five-Year Plan period was unusual five years in the development of China. Under the dual pressure of complex international environment and arduous domestic reform task,China made outstanding achievements in economic development,which lays a solid foundation for building a moderately prosperous society in all respects in the 13 th Five-Year Plan period. The key and difficult points of building a moderately prosperous society in all respects lie in solving issues concerning agriculture,farmers,and rural areas. The 18 th National Congress of the CPC stated that integrated urban and rural development is the fundamental approach for solving issues concerning agriculture,farmers,and rural areas. As a transitional form from rural areas to urban areas,small town play an important role in integrated urban and rural development. In the 13 th Five-Year Plan period,China should take a new road of characteristic urbanization,energetically develop key towns,central towns,and characteristic towns,use points to drive areas,and promote coordinated progress of urbanization construction and new countryside construction. Focusing on the objective of building a moderately prosperous society in all respects and taking Shangrao City as an example,we analyzed construction of small town,in order to provide scientific theoretical reference for urbanization development,plan preparation,and policy formulation of Shangrao City.展开更多
Based on the perspective of ecological concept,this study first interpreted the background of ecological civilization construction,and combed the relationship between ecological concept and small town planning.Second,...Based on the perspective of ecological concept,this study first interpreted the background of ecological civilization construction,and combed the relationship between ecological concept and small town planning.Second,it expounded the ecological problems of natural resources,economic development,landscape system,social humanities and other aspects in the construction of contemporary small towns.According to the study,the construction of small towns based on the ecological concept should establish the concept of "ecology first",practice "multiple compliance",coordinate the relationship with other planning,make reasonable planning and design in the aspects of town scale,functional orientation,structural form,road traffic,landscape style and features,humanistic characteristics,and strengthen the implementation,supervision and management of planning.Finally,summary and outlook was made,hoping that the study will be of reference value and guidance to the planning and construction of small towns.展开更多
Taiwan Residents producer Huang Hui-zhen directed the camera at her mother and herself,trying to communicate and reconcile with her mother through documentary.Different from other private record documentaries,the conf...Taiwan Residents producer Huang Hui-zhen directed the camera at her mother and herself,trying to communicate and reconcile with her mother through documentary.Different from other private record documentaries,the conflicts within the subject construction in Small Talk is no longer limited to“person to person”,“person and family”,or“parents and children”.Instead,it constructs the theme of an ordinary family struggling with a collection of social issues such as homosexuality,domestic violence,sexual assault,aboriginal Taiwan Residents culture,etc.展开更多
In the process of promoting the national territorial spatial planning system in all provinces, cities and counties, the geospatial database of “One Map” has realized the information sharing and collaborative work of...In the process of promoting the national territorial spatial planning system in all provinces, cities and counties, the geospatial database of “One Map” has realized the information sharing and collaborative work of multiple departments. Based on this, this paper intended to provide a set of standardized mapping models for industrial heritage storage, and through the establishment of the database to protect and reuse the status quo of industrial heritage research. This paper took the third-line construction industrial heritage of Mianyang “Two-Bomb City” as the research object, developed the relevant drawing standards of third-line industrial heritage database, and studied the database construction process. GIS technology is used to establish a geospatial database of the third-line industrial heritage in cooperation with the “One Map” system, in order to provide reference for the storage of the third-line industrial heritage in various places, and to protect and reuse the third-line industrial heritage from the perspectives of spatial factors, planning coordination and dynamic assessment.展开更多
According to the conditions to develop Long Stay in small tourism towns,the demonstration of Long Stay in the planning and construction of small towns was taken into consideration,and its benefits for tourism towns we...According to the conditions to develop Long Stay in small tourism towns,the demonstration of Long Stay in the planning and construction of small towns was taken into consideration,and its benefits for tourism towns were analyzed.The results showed that small tourism towns were endowed with sound conditions to develop Long Stay,which played its role in the overall planning of towns and would benefit the economic development of these towns.展开更多
BACKGROUND Somatostatin analogues are an established first-line therapy for well differentiated small bowel neuroendocrine tumours(Wd-SBNETs),while and peptide receptor radionuclide therapy(PRRT)is frequently used as ...BACKGROUND Somatostatin analogues are an established first-line therapy for well differentiated small bowel neuroendocrine tumours(Wd-SBNETs),while and peptide receptor radionuclide therapy(PRRT)is frequently used as a second-line therapy.Adequate treatment selection of third-line treatment remains challenging due to the limited prospective data currently available on the best therapeutic sequence.AIM To understand current practice and rationale for decision-making by physicians in the 3rd-line setting by building an online survey.METHODS Weighted average(WA)of likelihood of usage between responders(1 very unlikely;4 very likely)was used to reflect the relevance of factors explored.RESULTS Replies from representatives of 28 centers were received(5/8/2020-21/9/2020);medical oncologist(53.6%),gastroenterologist(17.9%);United Kingdom(21.4%),Spain(17.9%),Italy(14.3%).Majority from European Neuroendocrine Tumor Society(ENETS)Centres of Excellence(57.1%),who followed ENETS guidelines(82.1%).Generally speaking,3rd-line treatment for Wd-SBNETs was:everolimus(EVE)(66.7%),PRRT(18.5%),liver embolization(LE)(7.4%)and interferon-alpha(IFN)(3.7%);chemotherapy(0%);decision was based on clinical trial data(59.3%),or personal experience(22.2%).EVE was most likely used if Ki-67<10%(WA 3.27/4)or age<70 years(WA 3.23/4),in the 3rd-line setting(WA 3.23/4);regardless of presence/absence of carcinoid syndrome(CS),rate of progression or extent of disease.Chemotherapy was mainly utilised only if rapid progression(within 6 mo)(WA 3.35/4),Ki-6710%-20%(WA 2.77/4),negative somatostatin receptor imaging(WA 2.65/4)or high tumour burden(WA 2.77/4);temozolomide or streptozocin was used with capecitabine or 5-fluorouracil(5-FU)(57.7%),FOLFOX(5-FU combined with oxaliplatin)(23.1%).LE was selected if presence of CS(WA 3.24/4)or Ki-67<10%(WA 2.8/4),after progression to other treatments(WA 2.8/4).IFN was rarely used(WA 1.3/4).CONCLUSION Everolimus was the most frequently used therapeutic option in the third-line setting.The most important factors for decision-making included Ki-67,rate of progression,functionality and tumour burden;since this decision is based on multiple factors,it highlights the need for a multidisciplinary assessment.展开更多
文摘Existing problems of sewage treatment plants in small towns were summarized firstly,and then the developing trend of construction of sewage treatment plants in small towns was discussed from the aspects of project decision,site selection,design,processing technology and construction financing models. Finally,outlooks for its future development were proposed to provide reference for the construction of sewage treatment plants in small towns in future.
文摘Characteristic small cities and towns are the new vehicle for advancing new urbanization construction and supply-side reform.Zushan characteristic towns focus on tourism vacation,ecological livability,integration of production and cities,cultural heritage,poverty alleviation and other functions,and focus on building a new type of"product,city,and people"trinity,is a new benchmark for industrial transformation and upgrading.This article uses field surveys,interviews,and other methods to investigate the status quo of the construction of small towns with Zushan characteristics.Based on this,SWOT analysis of small towns is carried out,and the disadvantages and threats to its development are determined from the nature of towns and cities,infrastructure construction,and townships.Five suggestions were made for the construction of capital,the cultivation of special industries,and the detennination of the main body of urban construction.
基金Supported by the Knowledge Innovation Program of Chinese Academy of Sciences(KZCZ2-316)and Ecology and Environment Compensation Foundation from the Office of the TGP Construction commission of the State council of China(SX2001-021)
文摘Based on the five-year long dynamic tracking and investigation of the peasant households of the Lishu village, the influences by small town construction on the economy and employment of the original peasant households are discussed. On the one hand, small town construction plays a positive role in adjustment of the industrial structure of the original peasant households and in the transfer of their employment towards non-agricultural industries. On the other hand the economic growth of the original peasant households is not so well sustainable, and is so fluctuating. Moreover, the unbalance of income distribution of the said households has been furthered, and small town construction has made the existing labor surplus of the original peasant households more serious, particularly the women labor surplus.
基金Supported by the Land Use Plan Program of Dafang Bureau of Land and Resources[(2010)BCXY1209]the Sub-program"Graphics Construction in Dafang County"of the Land Use Plan in Dafang County of School of Economics,Guizhou University[(2011)1201]
文摘This paper is to examine the urban and rural construction land data of Dafang between basic year and final year based on country scale and spatial econometrics,and analyze its spatial pattern and change feature. According to the results,the construction lands in all the villages of Dafang County showed strong spatial autocorrelation and significant spatial cluster. After the analysis of local Moran's I,the construction lands in 381 villages of 36 counties presented strong activity. The original small-scale villages were gradually enlarging,which will not only gradually benefit local development,but also be in accordance with the strategy of " one city,one district,eight parks".
文摘There are many papers on red tide occurrences and eutrophication. Here, we use these data to examine the relationship between dam construction and red tide occurrence in Kesennuma Bay, Dokai Bay and the small bays of the Seto Inland Sea, Japan. Here, for the first time, differences in mechanisms of red tide occurrences in these small bays are demonstrated. Mud overflowing from dams likely induces red tides in these areas as the mud flows out from the mouth of the rivers, is carried along the coast by the longshore current, and then enters and is deposited into small bays. Red tide is considered to be induced by the accumulation of mud and siltation. From data on the locations and year of red tide occurrences in the Gulf of Mexico, the same mechanism as for the occurrence of red tide in small bays of Japanwas found to be applicable.
基金Supported by grants from the Jilin Health and Family Planning Commission Scientific Research Project(No.2014Z014)the "12th Five" Project of National Key Subject of New Drug Innovation(No.2013ZX09104001)
文摘Objective As there is currently no clear recommendation for third-line chemotherapy for small cell lung cancer (SCLC), its efficacy is unknown. To date, there have rarely been reports of Chinese patients with SCLC who received third-line chemotherapy. Therefore, we investigated the efficacy, safety, and prognostic factors of Chinese patients with SCLC treated with third-line chemotherapy. Methods A retrospective analysis of patients with SCLC who received third-line chemotherapy was performed. Results Between 2007 and 2013, 62 patients [62 men (75.6%), 20 women (24.4%); median age at the time of diagnosis, 55 years] received third-line chemotherapy at our center. Of these patients, 44 had limited-stage disease and 38 had extensive-stage disease. On third-line chemotherapy, 55 (67.1%) patients had an Eastern Cooperative Oncology Group performance status (ECOG PS) of 0-1, objective response rate of 15.9%, and median overall survival after third-line chemotherapy (OS-3) and median progres- sion-free survival after third-line chemotherapy (PFS-3) of 5.6 months and 3.0 months, respectively. On univariate analysis, PFS-3 was significantly related with ECOG PS (P = 0.005), response to second-line chemotherapy (P = 0.002), response to third-line chemotherapy (P 〈 0.001), and PFS after second-line chemotherapy (P = 0.026). OS-3 was significantly related with ECOG PS (P 〈 0.001), response to third-line chemotherapy (P = 0.033), PFS after first-line therapy (P = 0.044), and PFS after second-line therapy (PFS-2) (P = 0.007). On multivariate analysis, ECOG PS (P = 0.008) and response to third-line chemotherapy (P = 0.046) were independent prognostic factors for PFS-3, while ECOG PS (P = 0.007) and PFS-2 (P 〈 0.001) were independent prognostic factors for OS-3. Conclusion Few patients with SCLC receive third-line chemotherapy. Our findings suggest that patients with an ECOG PS 0-1 and PFS-2 for 〉3 months will be benefit from third-line chemotherapy, which should be actively offered to them.
文摘In recent years, China has been frequented by floods and droughts which has greatly evoked much concern from the Central Government about rural water conservancy construction. Irrigation is closely related to the "three rural" issues and concerns about the vital interests of farmers. To achieve a virtuous circle of agricultural water supply, it is necessary and urgent to establish Farmer Water User Association (FWUA) to participate in the construction, management and maintenance of small-scale irrigation system. Based on the survey on nationwide "Small-scale irrigation conditions", the roles of FWUA in the construction, management and maintenance of small-scale water conservancy have studied in this study.
文摘The 12 th Five-Year Plan period was unusual five years in the development of China. Under the dual pressure of complex international environment and arduous domestic reform task,China made outstanding achievements in economic development,which lays a solid foundation for building a moderately prosperous society in all respects in the 13 th Five-Year Plan period. The key and difficult points of building a moderately prosperous society in all respects lie in solving issues concerning agriculture,farmers,and rural areas. The 18 th National Congress of the CPC stated that integrated urban and rural development is the fundamental approach for solving issues concerning agriculture,farmers,and rural areas. As a transitional form from rural areas to urban areas,small town play an important role in integrated urban and rural development. In the 13 th Five-Year Plan period,China should take a new road of characteristic urbanization,energetically develop key towns,central towns,and characteristic towns,use points to drive areas,and promote coordinated progress of urbanization construction and new countryside construction. Focusing on the objective of building a moderately prosperous society in all respects and taking Shangrao City as an example,we analyzed construction of small town,in order to provide scientific theoretical reference for urbanization development,plan preparation,and policy formulation of Shangrao City.
文摘Based on the perspective of ecological concept,this study first interpreted the background of ecological civilization construction,and combed the relationship between ecological concept and small town planning.Second,it expounded the ecological problems of natural resources,economic development,landscape system,social humanities and other aspects in the construction of contemporary small towns.According to the study,the construction of small towns based on the ecological concept should establish the concept of "ecology first",practice "multiple compliance",coordinate the relationship with other planning,make reasonable planning and design in the aspects of town scale,functional orientation,structural form,road traffic,landscape style and features,humanistic characteristics,and strengthen the implementation,supervision and management of planning.Finally,summary and outlook was made,hoping that the study will be of reference value and guidance to the planning and construction of small towns.
文摘Taiwan Residents producer Huang Hui-zhen directed the camera at her mother and herself,trying to communicate and reconcile with her mother through documentary.Different from other private record documentaries,the conflicts within the subject construction in Small Talk is no longer limited to“person to person”,“person and family”,or“parents and children”.Instead,it constructs the theme of an ordinary family struggling with a collection of social issues such as homosexuality,domestic violence,sexual assault,aboriginal Taiwan Residents culture,etc.
文摘In the process of promoting the national territorial spatial planning system in all provinces, cities and counties, the geospatial database of “One Map” has realized the information sharing and collaborative work of multiple departments. Based on this, this paper intended to provide a set of standardized mapping models for industrial heritage storage, and through the establishment of the database to protect and reuse the status quo of industrial heritage research. This paper took the third-line construction industrial heritage of Mianyang “Two-Bomb City” as the research object, developed the relevant drawing standards of third-line industrial heritage database, and studied the database construction process. GIS technology is used to establish a geospatial database of the third-line industrial heritage in cooperation with the “One Map” system, in order to provide reference for the storage of the third-line industrial heritage in various places, and to protect and reuse the third-line industrial heritage from the perspectives of spatial factors, planning coordination and dynamic assessment.
文摘According to the conditions to develop Long Stay in small tourism towns,the demonstration of Long Stay in the planning and construction of small towns was taken into consideration,and its benefits for tourism towns were analyzed.The results showed that small tourism towns were endowed with sound conditions to develop Long Stay,which played its role in the overall planning of towns and would benefit the economic development of these towns.
基金Dr Angela Lamarca received funding from The Christie CharityDr.Joakim Crona received funding from CancerfondenThe design of the survey and its distribution was supported by COR2ED and the NETConnect group(funded by Ipsen).
文摘BACKGROUND Somatostatin analogues are an established first-line therapy for well differentiated small bowel neuroendocrine tumours(Wd-SBNETs),while and peptide receptor radionuclide therapy(PRRT)is frequently used as a second-line therapy.Adequate treatment selection of third-line treatment remains challenging due to the limited prospective data currently available on the best therapeutic sequence.AIM To understand current practice and rationale for decision-making by physicians in the 3rd-line setting by building an online survey.METHODS Weighted average(WA)of likelihood of usage between responders(1 very unlikely;4 very likely)was used to reflect the relevance of factors explored.RESULTS Replies from representatives of 28 centers were received(5/8/2020-21/9/2020);medical oncologist(53.6%),gastroenterologist(17.9%);United Kingdom(21.4%),Spain(17.9%),Italy(14.3%).Majority from European Neuroendocrine Tumor Society(ENETS)Centres of Excellence(57.1%),who followed ENETS guidelines(82.1%).Generally speaking,3rd-line treatment for Wd-SBNETs was:everolimus(EVE)(66.7%),PRRT(18.5%),liver embolization(LE)(7.4%)and interferon-alpha(IFN)(3.7%);chemotherapy(0%);decision was based on clinical trial data(59.3%),or personal experience(22.2%).EVE was most likely used if Ki-67<10%(WA 3.27/4)or age<70 years(WA 3.23/4),in the 3rd-line setting(WA 3.23/4);regardless of presence/absence of carcinoid syndrome(CS),rate of progression or extent of disease.Chemotherapy was mainly utilised only if rapid progression(within 6 mo)(WA 3.35/4),Ki-6710%-20%(WA 2.77/4),negative somatostatin receptor imaging(WA 2.65/4)or high tumour burden(WA 2.77/4);temozolomide or streptozocin was used with capecitabine or 5-fluorouracil(5-FU)(57.7%),FOLFOX(5-FU combined with oxaliplatin)(23.1%).LE was selected if presence of CS(WA 3.24/4)or Ki-67<10%(WA 2.8/4),after progression to other treatments(WA 2.8/4).IFN was rarely used(WA 1.3/4).CONCLUSION Everolimus was the most frequently used therapeutic option in the third-line setting.The most important factors for decision-making included Ki-67,rate of progression,functionality and tumour burden;since this decision is based on multiple factors,it highlights the need for a multidisciplinary assessment.