In this work,we study the linearized Landau equation with soft potentials and show that the smooth solution to the Cauchy problem with initial datum in L^(2)(ℝ^(3))enjoys an analytic regularization effect,and that the...In this work,we study the linearized Landau equation with soft potentials and show that the smooth solution to the Cauchy problem with initial datum in L^(2)(ℝ^(3))enjoys an analytic regularization effect,and that the evolution of the analytic radius is the same as the heat equations.展开更多
Lateral interaction in the biological brain is a key mechanism that underlies higher cognitive functions.Linear self‐organising map(SOM)introduces lateral interaction in a general form in which signals of any modalit...Lateral interaction in the biological brain is a key mechanism that underlies higher cognitive functions.Linear self‐organising map(SOM)introduces lateral interaction in a general form in which signals of any modality can be used.Some approaches directly incorporate SOM learning rules into neural networks,but incur complex operations and poor extendibility.The efficient way to implement lateral interaction in deep neural networks is not well established.The use of Laplacian Matrix‐based Smoothing(LS)regularisation is proposed for implementing lateral interaction in a concise form.The authors’derivation and experiments show that lateral interaction implemented by SOM model is a special case of LS‐regulated k‐means,and they both show the topology‐preserving capability.The authors also verify that LS‐regularisation can be used in conjunction with the end‐to‐end training paradigm in deep auto‐encoders.Additionally,the benefits of LS‐regularisation in relaxing the requirement of parameter initialisation in various models and improving the classification performance of prototype classifiers are evaluated.Furthermore,the topologically ordered structure introduced by LS‐regularisation in feature extractor can improve the generalisation performance on classification tasks.Overall,LS‐regularisation is an effective and efficient way to implement lateral interaction and can be easily extended to different models.展开更多
In this study,a common-node DEM-SPH coupling model based on the shared node method is proposed,and a fluid–structure coupling method using the common-node discrete element method-smoothed particle hydrodynamics(DS-SP...In this study,a common-node DEM-SPH coupling model based on the shared node method is proposed,and a fluid–structure coupling method using the common-node discrete element method-smoothed particle hydrodynamics(DS-SPH)method is developed using LS-DYNA software.The DEM and SPH are established on the same node to create common-node DEM-SPH particles,allowing for fluid–structure interactions.Numerical simulations of various scenarios,including water entry of a rigid sphere,dam-break propagation over wet beds,impact on an ice plate floating on water and ice accumulation on offshore structures,are conducted.The interaction between DS particles and SPH fluid and the crack generation mechanism and expansion characteristics of the ice plate under the interaction of structure and fluid are also studied.The results are compared with available data to verify the proposed coupling method.Notably,the simulation results demonstrated that controlling the cutoff pressure of internal SPH particles could effectively control particle splashing during ice crushing failure.展开更多
Residual strength is an indispensable factor in evaluating rock fracture,yet the current Smoothed Particle Hydrodynamics(SPH)framework rarely considers its influence when simulating fracture.An improved cracking strat...Residual strength is an indispensable factor in evaluating rock fracture,yet the current Smoothed Particle Hydrodynamics(SPH)framework rarely considers its influence when simulating fracture.An improved cracking strategy considering residual stress in the base bond SPH method was proposed to simulate failures in layered rocks and slopes and verified by experimental results and other simulation methods(i.e.,the discrete element method).Modified Mohr–Coulomb failure criterion was applied to distinguish the mixed failure of tensile and shear.Bond fracture markψwas introduced to improve the kernel function after tensile damage,and the calculation of residual stress after the damage was derived after shear damage.Numerical simulations were carried out to evaluate its performance under different stress and scale conditions and to verify its effectiveness in realistically reproducing crack initiation and propagation and coalescence,even fracture and separation.The results indicate that the improved cracking strategy precisely captures the fracture and failure pattern in layered rocks and rock slopes.The residual stress of brittle tock is correctly captured by the improved SPH method.The improved SPH method that considers residual strength shows an approximately 13%improvement in accuracy for the safety factor of anti-dip layered slopes compared to the method that does not consider residual strength,as validated against analytical solutions.We infer that the improved SPH method is effective and shows promise for applications to continuous and discontinuous rock masses.展开更多
The proposed robust reversible watermarking algorithm addresses the compatibility challenges between robustness and reversibility in existing video watermarking techniques by leveraging scene smoothness for frame grou...The proposed robust reversible watermarking algorithm addresses the compatibility challenges between robustness and reversibility in existing video watermarking techniques by leveraging scene smoothness for frame grouping videos.Grounded in the H.264 video coding standard,the algorithm first employs traditional robust watermark stitching technology to embed watermark information in the low-frequency coefficient domain of the U channel.Subsequently,it utilizes histogram migration techniques in the high-frequency coefficient domain of the U channel to embed auxiliary information,enabling successful watermark extraction and lossless recovery of the original video content.Experimental results demonstrate the algorithm’s strong imperceptibility,with each embedded frame in the experimental videos achieving a mean peak signal-to-noise ratio of 49.3830 dB and a mean structural similarity of 0.9996.Compared with the three comparison algorithms,the performance of the two experimental indexes is improved by 7.59%and 0.4%on average.At the same time,the proposed algorithm has strong robustness to both offline and online attacks:In the face of offline attacks,the average normalized correlation coefficient between the extracted watermark and the original watermark is 0.9989,and the average bit error rate is 0.0089.In the face of online attacks,the normalized correlation coefficient between the extracted watermark and the original watermark is 0.8840,and the mean bit error rate is 0.2269.Compared with the three comparison algorithms,the performance of the two experimental indexes is improved by 1.27%and 18.16%on average,highlighting the algorithm’s robustness.Furthermore,the algorithm exhibits low computational complexity,with the mean encoding and the mean decoding time differentials during experimental video processing being 3.934 and 2.273 s,respectively,underscoring its practical utility.展开更多
Predicting the response of liquefied natural gas(LNG)contained in vessels subjected to external waves is extremely important to ensure the safety of the transportation process.In this study,the coupled behavior due to...Predicting the response of liquefied natural gas(LNG)contained in vessels subjected to external waves is extremely important to ensure the safety of the transportation process.In this study,the coupled behavior due to ship motion and liquid tank sloshing has been simulated by the Smoothed-Particle Hydrodynamics(SPH)method.Firstly,the sloshing flow in a rectangular tank was simulated and the related loads were analyzed to verify and validate the accuracy of the present SPH solver.Then,a three-dimensional simplified LNG carrier model,including two prismatic liquid tanks and a wave tank,was introduced.Different conditions were examined corresponding to different wave lengths,wave heights,wave heading angles,and tank loading rates.Finally,the effects of liquid tank loading rate on LNG ship motions and sloshing loading were analyzed,thereby showing that the SPH method can effectively provide useful indications for the design of liquid cargo ships.展开更多
Angiotensin II (Ang II) is the main mediator of the Renin-Angiotensin-System acting on AT<sub>1</sub> and other AT receptors. It is regarded as a pleiotropic agent that induces many actions, including func...Angiotensin II (Ang II) is the main mediator of the Renin-Angiotensin-System acting on AT<sub>1</sub> and other AT receptors. It is regarded as a pleiotropic agent that induces many actions, including functioning as a growth factor, and as a contractile hormone, among others. The aim of this work was to examine the impact of Ang II on the expression and function of α<sub>1</sub>-adrenergic receptors (α<sub>1</sub>-ARs) in cultured rat aorta, and aorta-derived smooth muscle cells. Isolated Wistar rat aorta was incubated for 24 h in DMEM at 37˚C, then subjected to isometric tension and to the action of added norepinephrine, in concentration-response curves. Ang II was added (1 × 10<sup>−5</sup> M), and in some experiments, 5-Methylurapidil (α<sub>1A</sub>-AR antagonist), AH11110A (α<sub>1B</sub>-AR antagonist), or BMY-7378 (α<sub>1D</sub>-AR antagonist), were used to identify the α<sub>1</sub>-AR involved in the response. Desensitization of the contractile response to norepinephrine was observed due to incubation time, and by the Ang II action. α<sub>1D</sub>-AR was protected from desensitization by BMY-7378;while RS-100329 and prazosin partially mitigated desensitization. In another set of experiments, isolated aorta-derived smooth muscle cells were exposed to Ang II and α<sub>1</sub>-ARs proteins were evaluated. α<sub>1D</sub>-AR increased at 30 and 60 min post Ang II exposure, the α<sub>1A</sub>-AR diminished from 1 to 4 h, while α<sub>1B</sub>-AR remained unchanged over 24 h of Ang II exposure. Ang II induced an increase of α<sub>1D</sub>-AR at short times, and BMY-7378 protected α<sub>1D</sub>-AR from desensitization.展开更多
In this paper, we present a nonmonotone smoothing Newton algorithm for solving the circular cone programming(CCP) problem in which a linear function is minimized or maximized over the intersection of an affine space w...In this paper, we present a nonmonotone smoothing Newton algorithm for solving the circular cone programming(CCP) problem in which a linear function is minimized or maximized over the intersection of an affine space with the circular cone. Based on the relationship between the circular cone and the second-order cone(SOC), we reformulate the CCP problem as the second-order cone problem(SOCP). By extending the nonmonotone line search for unconstrained optimization to the CCP, a nonmonotone smoothing Newton method is proposed for solving the CCP. Under suitable assumptions, the proposed algorithm is shown to be globally and locally quadratically convergent. Some preliminary numerical results indicate the effectiveness of the proposed algorithm for solving the CCP.展开更多
In this article,a procedure for estimating the coefficient functions on the functional-coefficient regression models with different smoothing variables in different coefficient functions is defined.First step,by the l...In this article,a procedure for estimating the coefficient functions on the functional-coefficient regression models with different smoothing variables in different coefficient functions is defined.First step,by the local linear technique and the averaged method,the initial estimates of the coefficient functions are given.Second step,based on the initial estimates,the efficient estimates of the coefficient functions are proposed by a one-step back-fitting procedure.The efficient estimators share the same asymptotic normalities as the local linear estimators for the functional-coefficient models with a single smoothing variable in different functions.Two simulated examples show that the procedure is effective.展开更多
Data sparseness has been an inherited issue of statistical language models and smoothing method is usually used to resolve the zero count problems. In this paper, we studied empirically and analyzed the well-known smo...Data sparseness has been an inherited issue of statistical language models and smoothing method is usually used to resolve the zero count problems. In this paper, we studied empirically and analyzed the well-known smoothing methods of Good-Turing and advanced Good-Turing for language models on large sizes Chinese corpus. In the paper, ten models are generated sequentially on various size of corpus, from 30 M to 300 M Chinese words of CGW corpus. In our experiments, the smoothing methods;Good-Turing and Advanced Good-Turing smoothing are evaluated on inside testing and outside testing. Based on experiments results, we analyzed further the trends of perplexity of smoothing methods, which are useful for employing the effective smoothing methods to alleviate the issue of data sparseness on various sizes of language models. Finally, some helpful observations are described in detail.展开更多
As the mesh models usually contain noise data,it is necessary to eliminate the noises and smooth the mesh.But existed methods always lose geometric features during the smoothing process.Hence,the noise is considered a...As the mesh models usually contain noise data,it is necessary to eliminate the noises and smooth the mesh.But existed methods always lose geometric features during the smoothing process.Hence,the noise is considered as a kind of random signal with high frequency,and then the mesh model smoothing is operated with signal processing theory.Local wave analysis is used to deal with geometric signal,and then a novel mesh smoothing method based on the local wave is proposed.The proposed method includes following steps:Firstly,analyze the principle of local wave decomposition for 1D signal,and expand it to 2D signal and 3D spherical surface signal processing;Secondly,map the mesh to the spherical surface with parameterization,resample the spherical mesh and decompose the spherical signals by local wave analysis;Thirdly,propose the coordinate smoothing and radical radius smoothing methods,the former filters the mesh points' coordinates by local wave,and the latter filters the radical radius from their geometric center to mesh points by local wave;Finally,remove the high-frequency component of spherical signal,and obtain the smooth mesh model with inversely mapping from the spherical signal.Several mesh models with Gaussian noise are processed by local wave based method and other compared methods.The results show that local wave based method can obtain better smoothing performance,and reserve more original geometric features at the same time.展开更多
In this article, we study the analytical smoothing effect of Cauchy problem for the incompressible Boussinesq equations. Precisely, we use the Fourier method to prove that the Sobolev H^1 -solution to the incompressib...In this article, we study the analytical smoothing effect of Cauchy problem for the incompressible Boussinesq equations. Precisely, we use the Fourier method to prove that the Sobolev H^1 -solution to the incompressible Boussinesq equations in periodic domain is analytic for any positive time. So the incompressible Boussinesq equations admit exactly same smoothing effect properties of incompressible Navier-Stokes equations.展开更多
Multipath influence on code range under static condition is described firstly in this paper, and the problem that to what extent the phase-aided smoothing can mitigate multipath interference is detailed. Some problems...Multipath influence on code range under static condition is described firstly in this paper, and the problem that to what extent the phase-aided smoothing can mitigate multipath interference is detailed. Some problems regarding smoothing and mitigation are discussed. Suggestions based on the analysis has been made.展开更多
The paper uses Euclidean Jordan algebras as a basic tool to extend smoothing functions, which include the Chen-Mangasarian class and the Fischer-Burmeister smoothing functions, to symmetric cone complementarity proble...The paper uses Euclidean Jordan algebras as a basic tool to extend smoothing functions, which include the Chen-Mangasarian class and the Fischer-Burmeister smoothing functions, to symmetric cone complementarity problems. Computable formulas for these functions and their Jacobians are derived. In addition, it is shown that these functions are Lipschitz continuous with respect to parameter # and continuously differentiable on J × J for any μ 〉 0.展开更多
In this article, we use penalized spline to estimate the hazard function from a set of censored failure time data. A new approach to estimate the amount of smoothing is provided. Under regularity conditions we establi...In this article, we use penalized spline to estimate the hazard function from a set of censored failure time data. A new approach to estimate the amount of smoothing is provided. Under regularity conditions we establish the consistency and the asymptotic normality of the penalized likelihood estimators. Numerical studies and an example are conducted to evaluate the performances of the new procedure.展开更多
The extraction of spectral parameters is very difficult because of the limited energy resolution for NaI( TI) gamma-ray detectors. For statistical fluctuation of radioactivity under complex environment,some smoothing ...The extraction of spectral parameters is very difficult because of the limited energy resolution for NaI( TI) gamma-ray detectors. For statistical fluctuation of radioactivity under complex environment,some smoothing filtering methods are proposed to solve the problem. These methods include adopting method of arithmetic moving average,center of gravity,least squares of polynomial,slide converter of discrete funcion convolution etc. The process of spectrum data is realized,and the results are assessed in H / FWHM( Peak High / Full Width at Half Maximum) and peak area based on the Matlab programming. The results indicate that different methods smoothed spectrum have respective superiority in different ergoregion,but the Gaussian function theory in discrete function convolution slide method is used to filter the complex γ-spectrum on Embedded system platform,and the statistical fluctuation of γ-spectrum is filtered well.展开更多
In order to achieve refined precipitation grid data with high accuracy and high spatial resolution,hourly precipitation grid dataset with 1 km spatial resolution in Anhui Province from May to September (in the rainy s...In order to achieve refined precipitation grid data with high accuracy and high spatial resolution,hourly precipitation grid dataset with 1 km spatial resolution in Anhui Province from May to September (in the rainy season) in 2016 and from August 2017 to July 2018 was established based on thin plate smoothing spline (TPS),which meets the needs of climate change research and meteorological disaster risk assessment.The interpolation errors were then analyzed.The grid precipitation product obtained based on thin plate smoothing spline,CLDAS-FAST and CLDAS-FRT were evaluated.The results show that the interpolated values of hourly precipitation by thin plate smoothing spline are close to the observed values in the rainy season of 2016.The errors are generally below 0.9 mm/h.However,the errors of precipitation in the mountainous areas of eastern Huaibei and western Anhui are above 1.2 mm/h.On monthly scale,the errors in June and July are the largest,and the proportion of absolute values of the errors ≥2 mm/h is up to 2.0% in June and 2.2% in July.The errors in September are the smallest,and the proportion of absolute values of the errors ≥2 mm/h is only 0.6%.The root mean square (RMSE) is only 0.37 mm/h,and the correlation coefficient (COR) is 0.93.The interpolation accuracy of CLDAS-FRT is the highest,with the smallest RMSE (0.65 mm/h) and mean error ( ME =0.01 mm/h),and the largest COR (0.81).The accuracy of the precipitation product obtained by thin plate smoothing spline interpolation is close to that of CLDAS-FAST.Its RMSE is up to 0.80 mm/h,and its ME is only -0.01 mm/h.Its COR is 0.73,but its bias (BIAS) is up to 1.06 mm/h.展开更多
A novel method to estimate DOA of coherent signals impinging on a uniform circular array( UCA) is presented in this paper. A virtual uniform linear array (VULA) is first derived by using spatial DFT technique, transfo...A novel method to estimate DOA of coherent signals impinging on a uniform circular array( UCA) is presented in this paper. A virtual uniform linear array (VULA) is first derived by using spatial DFT technique, transforming the UCA from element space to phase mode space to obtain the properties of ordinary ULA, and then the well known spatial smoothing technique is applied to the VULA so that the lost rank of covariance matrix due to signal coherence can be retrieved. This method makes it feasible to use the simple MUSIC algorithm to estimate DOA of coherent signals impinging on a UCA without heavy computation burden. Simulation results strongly verify the effectiveness of the algorithm.展开更多
In this paper, we give a smoothing neural network algorithm for absolute value equations (AVE). By using smoothing function, we reformulate the AVE as a differentiable unconstrained optimization and we establish a ste...In this paper, we give a smoothing neural network algorithm for absolute value equations (AVE). By using smoothing function, we reformulate the AVE as a differentiable unconstrained optimization and we establish a steep descent method to solve it. We prove the stability and the equilibrium state of the neural network to be a solution of the AVE. The numerical tests show the efficient of the proposed algorithm.展开更多
基金supported by the Natural Science Foundation of Hubei Province,China (2022CFB444)the Key Laboratory of Mathematical Modelling and High Performance Computing of Air Vehicles (NUAA)+1 种基金supported by the NSFC (12031006)the Fundamental Research Funds for the Central Universities of China.
文摘In this work,we study the linearized Landau equation with soft potentials and show that the smooth solution to the Cauchy problem with initial datum in L^(2)(ℝ^(3))enjoys an analytic regularization effect,and that the evolution of the analytic radius is the same as the heat equations.
基金supported by the National Natural Science Foundation of China grants 61836014 to CL,and the STI2030‐Major Projects(2022ZD0205100)the Strategic Priority Research Program of Chinese Academy of Science,Grant No.XDB32010300+1 种基金Shanghai Municipal Science and Technology Major Project(Grant No.2018SHZDZX05)the Innovation Academy of Artificial Intelligence,Chinese Academy of Sciences to ZW.
文摘Lateral interaction in the biological brain is a key mechanism that underlies higher cognitive functions.Linear self‐organising map(SOM)introduces lateral interaction in a general form in which signals of any modality can be used.Some approaches directly incorporate SOM learning rules into neural networks,but incur complex operations and poor extendibility.The efficient way to implement lateral interaction in deep neural networks is not well established.The use of Laplacian Matrix‐based Smoothing(LS)regularisation is proposed for implementing lateral interaction in a concise form.The authors’derivation and experiments show that lateral interaction implemented by SOM model is a special case of LS‐regulated k‐means,and they both show the topology‐preserving capability.The authors also verify that LS‐regularisation can be used in conjunction with the end‐to‐end training paradigm in deep auto‐encoders.Additionally,the benefits of LS‐regularisation in relaxing the requirement of parameter initialisation in various models and improving the classification performance of prototype classifiers are evaluated.Furthermore,the topologically ordered structure introduced by LS‐regularisation in feature extractor can improve the generalisation performance on classification tasks.Overall,LS‐regularisation is an effective and efficient way to implement lateral interaction and can be easily extended to different models.
基金supported by the National Natural Science Foundation of China(Grant No.52201323).
文摘In this study,a common-node DEM-SPH coupling model based on the shared node method is proposed,and a fluid–structure coupling method using the common-node discrete element method-smoothed particle hydrodynamics(DS-SPH)method is developed using LS-DYNA software.The DEM and SPH are established on the same node to create common-node DEM-SPH particles,allowing for fluid–structure interactions.Numerical simulations of various scenarios,including water entry of a rigid sphere,dam-break propagation over wet beds,impact on an ice plate floating on water and ice accumulation on offshore structures,are conducted.The interaction between DS particles and SPH fluid and the crack generation mechanism and expansion characteristics of the ice plate under the interaction of structure and fluid are also studied.The results are compared with available data to verify the proposed coupling method.Notably,the simulation results demonstrated that controlling the cutoff pressure of internal SPH particles could effectively control particle splashing during ice crushing failure.
基金funded by the National Key Research and Development Program of China(Grant No.2023YFC3008300,Grant No.2019YFC1509702)the National Natural Science Foundation of China(Grant No.42172296).
文摘Residual strength is an indispensable factor in evaluating rock fracture,yet the current Smoothed Particle Hydrodynamics(SPH)framework rarely considers its influence when simulating fracture.An improved cracking strategy considering residual stress in the base bond SPH method was proposed to simulate failures in layered rocks and slopes and verified by experimental results and other simulation methods(i.e.,the discrete element method).Modified Mohr–Coulomb failure criterion was applied to distinguish the mixed failure of tensile and shear.Bond fracture markψwas introduced to improve the kernel function after tensile damage,and the calculation of residual stress after the damage was derived after shear damage.Numerical simulations were carried out to evaluate its performance under different stress and scale conditions and to verify its effectiveness in realistically reproducing crack initiation and propagation and coalescence,even fracture and separation.The results indicate that the improved cracking strategy precisely captures the fracture and failure pattern in layered rocks and rock slopes.The residual stress of brittle tock is correctly captured by the improved SPH method.The improved SPH method that considers residual strength shows an approximately 13%improvement in accuracy for the safety factor of anti-dip layered slopes compared to the method that does not consider residual strength,as validated against analytical solutions.We infer that the improved SPH method is effective and shows promise for applications to continuous and discontinuous rock masses.
基金supported in part by the National Natural Science Foundation of China under Grants 62202496,62272478the Basic Frontier Innovation Project of Engineering university of People Armed Police under Grants WJY202314,WJY202221.
文摘The proposed robust reversible watermarking algorithm addresses the compatibility challenges between robustness and reversibility in existing video watermarking techniques by leveraging scene smoothness for frame grouping videos.Grounded in the H.264 video coding standard,the algorithm first employs traditional robust watermark stitching technology to embed watermark information in the low-frequency coefficient domain of the U channel.Subsequently,it utilizes histogram migration techniques in the high-frequency coefficient domain of the U channel to embed auxiliary information,enabling successful watermark extraction and lossless recovery of the original video content.Experimental results demonstrate the algorithm’s strong imperceptibility,with each embedded frame in the experimental videos achieving a mean peak signal-to-noise ratio of 49.3830 dB and a mean structural similarity of 0.9996.Compared with the three comparison algorithms,the performance of the two experimental indexes is improved by 7.59%and 0.4%on average.At the same time,the proposed algorithm has strong robustness to both offline and online attacks:In the face of offline attacks,the average normalized correlation coefficient between the extracted watermark and the original watermark is 0.9989,and the average bit error rate is 0.0089.In the face of online attacks,the normalized correlation coefficient between the extracted watermark and the original watermark is 0.8840,and the mean bit error rate is 0.2269.Compared with the three comparison algorithms,the performance of the two experimental indexes is improved by 1.27%and 18.16%on average,highlighting the algorithm’s robustness.Furthermore,the algorithm exhibits low computational complexity,with the mean encoding and the mean decoding time differentials during experimental video processing being 3.934 and 2.273 s,respectively,underscoring its practical utility.
基金the National Natural Science Foundation of China(No.52271316)the Guangdong Basic and Applied Basic Research Foundation(No.2023A1515030262).
文摘Predicting the response of liquefied natural gas(LNG)contained in vessels subjected to external waves is extremely important to ensure the safety of the transportation process.In this study,the coupled behavior due to ship motion and liquid tank sloshing has been simulated by the Smoothed-Particle Hydrodynamics(SPH)method.Firstly,the sloshing flow in a rectangular tank was simulated and the related loads were analyzed to verify and validate the accuracy of the present SPH solver.Then,a three-dimensional simplified LNG carrier model,including two prismatic liquid tanks and a wave tank,was introduced.Different conditions were examined corresponding to different wave lengths,wave heights,wave heading angles,and tank loading rates.Finally,the effects of liquid tank loading rate on LNG ship motions and sloshing loading were analyzed,thereby showing that the SPH method can effectively provide useful indications for the design of liquid cargo ships.
文摘Angiotensin II (Ang II) is the main mediator of the Renin-Angiotensin-System acting on AT<sub>1</sub> and other AT receptors. It is regarded as a pleiotropic agent that induces many actions, including functioning as a growth factor, and as a contractile hormone, among others. The aim of this work was to examine the impact of Ang II on the expression and function of α<sub>1</sub>-adrenergic receptors (α<sub>1</sub>-ARs) in cultured rat aorta, and aorta-derived smooth muscle cells. Isolated Wistar rat aorta was incubated for 24 h in DMEM at 37˚C, then subjected to isometric tension and to the action of added norepinephrine, in concentration-response curves. Ang II was added (1 × 10<sup>−5</sup> M), and in some experiments, 5-Methylurapidil (α<sub>1A</sub>-AR antagonist), AH11110A (α<sub>1B</sub>-AR antagonist), or BMY-7378 (α<sub>1D</sub>-AR antagonist), were used to identify the α<sub>1</sub>-AR involved in the response. Desensitization of the contractile response to norepinephrine was observed due to incubation time, and by the Ang II action. α<sub>1D</sub>-AR was protected from desensitization by BMY-7378;while RS-100329 and prazosin partially mitigated desensitization. In another set of experiments, isolated aorta-derived smooth muscle cells were exposed to Ang II and α<sub>1</sub>-ARs proteins were evaluated. α<sub>1D</sub>-AR increased at 30 and 60 min post Ang II exposure, the α<sub>1A</sub>-AR diminished from 1 to 4 h, while α<sub>1B</sub>-AR remained unchanged over 24 h of Ang II exposure. Ang II induced an increase of α<sub>1D</sub>-AR at short times, and BMY-7378 protected α<sub>1D</sub>-AR from desensitization.
基金supported by the National Natural Science Foundation of China(11401126,71471140 and 11361018)Guangxi Natural Science Foundation(2016GXNSFBA380102 and 2014GXNSFFA118001)+2 种基金Guangxi Key Laboratory of Cryptography and Information Security(GCIS201618)Guangxi Key Laboratory of Automatic Detecting Technology and Instruments(YQ15112 and YQ16112)China
文摘In this paper, we present a nonmonotone smoothing Newton algorithm for solving the circular cone programming(CCP) problem in which a linear function is minimized or maximized over the intersection of an affine space with the circular cone. Based on the relationship between the circular cone and the second-order cone(SOC), we reformulate the CCP problem as the second-order cone problem(SOCP). By extending the nonmonotone line search for unconstrained optimization to the CCP, a nonmonotone smoothing Newton method is proposed for solving the CCP. Under suitable assumptions, the proposed algorithm is shown to be globally and locally quadratically convergent. Some preliminary numerical results indicate the effectiveness of the proposed algorithm for solving the CCP.
文摘In this article,a procedure for estimating the coefficient functions on the functional-coefficient regression models with different smoothing variables in different coefficient functions is defined.First step,by the local linear technique and the averaged method,the initial estimates of the coefficient functions are given.Second step,based on the initial estimates,the efficient estimates of the coefficient functions are proposed by a one-step back-fitting procedure.The efficient estimators share the same asymptotic normalities as the local linear estimators for the functional-coefficient models with a single smoothing variable in different functions.Two simulated examples show that the procedure is effective.
文摘Data sparseness has been an inherited issue of statistical language models and smoothing method is usually used to resolve the zero count problems. In this paper, we studied empirically and analyzed the well-known smoothing methods of Good-Turing and advanced Good-Turing for language models on large sizes Chinese corpus. In the paper, ten models are generated sequentially on various size of corpus, from 30 M to 300 M Chinese words of CGW corpus. In our experiments, the smoothing methods;Good-Turing and Advanced Good-Turing smoothing are evaluated on inside testing and outside testing. Based on experiments results, we analyzed further the trends of perplexity of smoothing methods, which are useful for employing the effective smoothing methods to alleviate the issue of data sparseness on various sizes of language models. Finally, some helpful observations are described in detail.
基金supported by National Natural Science Foundation of China (Grant No. 61075118,Grant No. 61005056,Grant No. 60975016)National Key Technology Support Program of China (Grant No. 2007BAH11B02)+1 种基金Zhejiang Provincial Natural Science Foundation of China (Grant No. Y1100880)Open Project Program of State Key Laboratory of CAD&CG of China (Grant No. A0906)
文摘As the mesh models usually contain noise data,it is necessary to eliminate the noises and smooth the mesh.But existed methods always lose geometric features during the smoothing process.Hence,the noise is considered as a kind of random signal with high frequency,and then the mesh model smoothing is operated with signal processing theory.Local wave analysis is used to deal with geometric signal,and then a novel mesh smoothing method based on the local wave is proposed.The proposed method includes following steps:Firstly,analyze the principle of local wave decomposition for 1D signal,and expand it to 2D signal and 3D spherical surface signal processing;Secondly,map the mesh to the spherical surface with parameterization,resample the spherical mesh and decompose the spherical signals by local wave analysis;Thirdly,propose the coordinate smoothing and radical radius smoothing methods,the former filters the mesh points' coordinates by local wave,and the latter filters the radical radius from their geometric center to mesh points by local wave;Finally,remove the high-frequency component of spherical signal,and obtain the smooth mesh model with inversely mapping from the spherical signal.Several mesh models with Gaussian noise are processed by local wave based method and other compared methods.The results show that local wave based method can obtain better smoothing performance,and reserve more original geometric features at the same time.
基金supported partially by "The Fundamental Research Funds for Central Universities of China"
文摘In this article, we study the analytical smoothing effect of Cauchy problem for the incompressible Boussinesq equations. Precisely, we use the Fourier method to prove that the Sobolev H^1 -solution to the incompressible Boussinesq equations in periodic domain is analytic for any positive time. So the incompressible Boussinesq equations admit exactly same smoothing effect properties of incompressible Navier-Stokes equations.
基金Project supported by Opening Research Foundation from LIESMARS (NoWKL(97)0103)
文摘Multipath influence on code range under static condition is described firstly in this paper, and the problem that to what extent the phase-aided smoothing can mitigate multipath interference is detailed. Some problems regarding smoothing and mitigation are discussed. Suggestions based on the analysis has been made.
基金Supported by the Funds of Ministry of Education of China for PhD (20020141013)the NNSF of China (10471015).
文摘The paper uses Euclidean Jordan algebras as a basic tool to extend smoothing functions, which include the Chen-Mangasarian class and the Fischer-Burmeister smoothing functions, to symmetric cone complementarity problems. Computable formulas for these functions and their Jacobians are derived. In addition, it is shown that these functions are Lipschitz continuous with respect to parameter # and continuously differentiable on J × J for any μ 〉 0.
基金supported by the Natural Science Foundation of China(10771017,10971015,10231030)Key Project to Ministry of Education of the People’s Republic of China(309007)
文摘In this article, we use penalized spline to estimate the hazard function from a set of censored failure time data. A new approach to estimate the amount of smoothing is provided. Under regularity conditions we establish the consistency and the asymptotic normality of the penalized likelihood estimators. Numerical studies and an example are conducted to evaluate the performances of the new procedure.
基金Sponsored by the Natural Science Fundation of Jiangxi Province(Grant No.20114BAB211026 and 20122BAB201028)the Open Science Fund from Key Laboratory of Radioactive Geology and Exploration Technology Fundamental Science for National Defense,East China Institute of Technology(Grant No.2010RGET11)
文摘The extraction of spectral parameters is very difficult because of the limited energy resolution for NaI( TI) gamma-ray detectors. For statistical fluctuation of radioactivity under complex environment,some smoothing filtering methods are proposed to solve the problem. These methods include adopting method of arithmetic moving average,center of gravity,least squares of polynomial,slide converter of discrete funcion convolution etc. The process of spectrum data is realized,and the results are assessed in H / FWHM( Peak High / Full Width at Half Maximum) and peak area based on the Matlab programming. The results indicate that different methods smoothed spectrum have respective superiority in different ergoregion,but the Gaussian function theory in discrete function convolution slide method is used to filter the complex γ-spectrum on Embedded system platform,and the statistical fluctuation of γ-spectrum is filtered well.
基金Supported by New Technology Integration Project of Anhui Meteorological Bureau(AHXJ201704)Project for Masters and Doctors of Anhui Meteorological Bureau(RC201701)
文摘In order to achieve refined precipitation grid data with high accuracy and high spatial resolution,hourly precipitation grid dataset with 1 km spatial resolution in Anhui Province from May to September (in the rainy season) in 2016 and from August 2017 to July 2018 was established based on thin plate smoothing spline (TPS),which meets the needs of climate change research and meteorological disaster risk assessment.The interpolation errors were then analyzed.The grid precipitation product obtained based on thin plate smoothing spline,CLDAS-FAST and CLDAS-FRT were evaluated.The results show that the interpolated values of hourly precipitation by thin plate smoothing spline are close to the observed values in the rainy season of 2016.The errors are generally below 0.9 mm/h.However,the errors of precipitation in the mountainous areas of eastern Huaibei and western Anhui are above 1.2 mm/h.On monthly scale,the errors in June and July are the largest,and the proportion of absolute values of the errors ≥2 mm/h is up to 2.0% in June and 2.2% in July.The errors in September are the smallest,and the proportion of absolute values of the errors ≥2 mm/h is only 0.6%.The root mean square (RMSE) is only 0.37 mm/h,and the correlation coefficient (COR) is 0.93.The interpolation accuracy of CLDAS-FRT is the highest,with the smallest RMSE (0.65 mm/h) and mean error ( ME =0.01 mm/h),and the largest COR (0.81).The accuracy of the precipitation product obtained by thin plate smoothing spline interpolation is close to that of CLDAS-FAST.Its RMSE is up to 0.80 mm/h,and its ME is only -0.01 mm/h.Its COR is 0.73,but its bias (BIAS) is up to 1.06 mm/h.
文摘A novel method to estimate DOA of coherent signals impinging on a uniform circular array( UCA) is presented in this paper. A virtual uniform linear array (VULA) is first derived by using spatial DFT technique, transforming the UCA from element space to phase mode space to obtain the properties of ordinary ULA, and then the well known spatial smoothing technique is applied to the VULA so that the lost rank of covariance matrix due to signal coherence can be retrieved. This method makes it feasible to use the simple MUSIC algorithm to estimate DOA of coherent signals impinging on a UCA without heavy computation burden. Simulation results strongly verify the effectiveness of the algorithm.
文摘In this paper, we give a smoothing neural network algorithm for absolute value equations (AVE). By using smoothing function, we reformulate the AVE as a differentiable unconstrained optimization and we establish a steep descent method to solve it. We prove the stability and the equilibrium state of the neural network to be a solution of the AVE. The numerical tests show the efficient of the proposed algorithm.