Introduction: Leukocyte and platelet-rich fibrin (L-PRF) is an emerging material in dentistry, however, there are controversies surrounding its effectiveness. Despite the amount of literature available, debates regard...Introduction: Leukocyte and platelet-rich fibrin (L-PRF) is an emerging material in dentistry, however, there are controversies surrounding its effectiveness. Despite the amount of literature available, debates regarding its effect continue. This review aims to summarize and clarify the data surrounding the use of L-PRF in promoting the healing of extraction sockets, which may offer a better outcome for future treatments. Purpose: The purpose of this review is to evaluate the current literature on the use of L-PRF in promoting the healing of extraction sockets, and to provide a comprehensive overview of the available evidence. Methods: A comprehensive computer-based search of databases such as PubMed, Medline, and Cochrane Library was conducted. Results: The results of this review suggest that L-PRF has shown promise in promoting early healing of extraction sockets, but the evidence for its effectiveness over a longer period is limited. Conclusion: Although L-PRF has shown promising results in the early healing periods, its effectiveness over a longer healing period cannot be confirmed based on the available data. More clinical trials with standardized protocols and consistent measurement methods are needed to establish the role of L-PRF in enhancing the healing of extraction sockets.展开更多
Integrating micro-optical components at the end facet of an optical fiber enables compact optics to shape the output beam(e.g.collimating,focusing,and coupling to free space elements or photonic integrated circuits).H...Integrating micro-optical components at the end facet of an optical fiber enables compact optics to shape the output beam(e.g.collimating,focusing,and coupling to free space elements or photonic integrated circuits).However,the scalability of this approach is a longstanding challenge as these components must be aligned onto individual fiber facets.In this paper,we propose a socket that enables easy slotting of fibers,self-alignment,and coupling onto micro-optical components.This integrated socket can be detached from the substrate upon fiber insertion to create a stand-alone optical system.Fabrication is done using nanoscale 3D printing via two-photon polymerization lithography onto glass substrates,which allows multiple sockets to be patterned in a single print.We investigated variations in socket design and evaluated the performance of optical elements for telecom wavelengths.We obtained an alignment accuracy of∼3.5μm.These socket designs can be customized for high efficiency chip to fiber coupling and extended to other spectral ranges for free-form optics.展开更多
文摘Introduction: Leukocyte and platelet-rich fibrin (L-PRF) is an emerging material in dentistry, however, there are controversies surrounding its effectiveness. Despite the amount of literature available, debates regarding its effect continue. This review aims to summarize and clarify the data surrounding the use of L-PRF in promoting the healing of extraction sockets, which may offer a better outcome for future treatments. Purpose: The purpose of this review is to evaluate the current literature on the use of L-PRF in promoting the healing of extraction sockets, and to provide a comprehensive overview of the available evidence. Methods: A comprehensive computer-based search of databases such as PubMed, Medline, and Cochrane Library was conducted. Results: The results of this review suggest that L-PRF has shown promise in promoting early healing of extraction sockets, but the evidence for its effectiveness over a longer period is limited. Conclusion: Although L-PRF has shown promising results in the early healing periods, its effectiveness over a longer healing period cannot be confirmed based on the available data. More clinical trials with standardized protocols and consistent measurement methods are needed to establish the role of L-PRF in enhancing the healing of extraction sockets.
基金funded by Singapore University of Technology and Design(SUTD)—Temasek Lab through the grant IGDSP1602051。
文摘Integrating micro-optical components at the end facet of an optical fiber enables compact optics to shape the output beam(e.g.collimating,focusing,and coupling to free space elements or photonic integrated circuits).However,the scalability of this approach is a longstanding challenge as these components must be aligned onto individual fiber facets.In this paper,we propose a socket that enables easy slotting of fibers,self-alignment,and coupling onto micro-optical components.This integrated socket can be detached from the substrate upon fiber insertion to create a stand-alone optical system.Fabrication is done using nanoscale 3D printing via two-photon polymerization lithography onto glass substrates,which allows multiple sockets to be patterned in a single print.We investigated variations in socket design and evaluated the performance of optical elements for telecom wavelengths.We obtained an alignment accuracy of∼3.5μm.These socket designs can be customized for high efficiency chip to fiber coupling and extended to other spectral ranges for free-form optics.
