The culture of every nation is bound to develop and make progress along with social development and progress. This is true, too, of Tibetan culture. As China furthers the cause of building socialism with Chinese chara...The culture of every nation is bound to develop and make progress along with social development and progress. This is true, too, of Tibetan culture. As China furthers the cause of building socialism with Chinese characteristics, a new progressive culture will keep replacing an old and backward culture. Any attempt to impede and reverse such progress constitutes real destruction of a culture. Such an attempt can never succeed. Nor will the attempt of the Dalai Lama.展开更多
背景与目的所谓肺硬化性血管瘤(so-called pul monary sclerosing hemangioma,PSH)是一种迄今未能确定其组织来源及性质的少见肺部肿瘤,多年来一直是人们研究的热点。本研究通过检测E-cad-herin、β-catenin和p120ctn在PSH表面立方细胞...背景与目的所谓肺硬化性血管瘤(so-called pul monary sclerosing hemangioma,PSH)是一种迄今未能确定其组织来源及性质的少见肺部肿瘤,多年来一直是人们研究的热点。本研究通过检测E-cad-herin、β-catenin和p120ctn在PSH表面立方细胞和间质多角形细胞的免疫表型以探讨其组织来源。方法采用S-P免疫组化法检测25例手术切除PSH标本及8例肺炎性假瘤标本的E-cadherin、β-catenin和p120ctn表达情况。结果25例PSH的立方细胞中,三种上皮粘附分子E-cadherin、β-catenin和p120ctn均呈胞膜强阳性表达,β-catenin在胞膜强阳性表达的同时有胞质表达。而在多角形细胞中,E-cadherin表达缺失,β-catenin胞膜表达缺失伴部分胞质表达,p120ctn胞质表达为主伴少量胞膜表达;三种粘附分子在多角形细胞中的表达存在异质性。血管瘤样区的腔内衬细胞E-cadherin、β-catenin和p120ctn均呈胞质胞膜阳性表达。8例肺炎性假瘤中增生的Ⅱ型肺泡细胞E-cadherin、β-catenin和p120ctn表达与PSH中立方细胞的表达情况相同。结论PSH中的立方细胞可能是增生的Ⅱ型肺泡细胞,而多角形细胞为肿瘤的实质细胞且缺乏分化成熟的上皮细胞所具有的E-cadherin/catenin复合体。血管瘤样区的腔内衬细胞是与立方细胞相同的上皮细胞而非血管内皮细胞。展开更多
文摘The culture of every nation is bound to develop and make progress along with social development and progress. This is true, too, of Tibetan culture. As China furthers the cause of building socialism with Chinese characteristics, a new progressive culture will keep replacing an old and backward culture. Any attempt to impede and reverse such progress constitutes real destruction of a culture. Such an attempt can never succeed. Nor will the attempt of the Dalai Lama.
文摘背景与目的所谓肺硬化性血管瘤(so-called pul monary sclerosing hemangioma,PSH)是一种迄今未能确定其组织来源及性质的少见肺部肿瘤,多年来一直是人们研究的热点。本研究通过检测E-cad-herin、β-catenin和p120ctn在PSH表面立方细胞和间质多角形细胞的免疫表型以探讨其组织来源。方法采用S-P免疫组化法检测25例手术切除PSH标本及8例肺炎性假瘤标本的E-cadherin、β-catenin和p120ctn表达情况。结果25例PSH的立方细胞中,三种上皮粘附分子E-cadherin、β-catenin和p120ctn均呈胞膜强阳性表达,β-catenin在胞膜强阳性表达的同时有胞质表达。而在多角形细胞中,E-cadherin表达缺失,β-catenin胞膜表达缺失伴部分胞质表达,p120ctn胞质表达为主伴少量胞膜表达;三种粘附分子在多角形细胞中的表达存在异质性。血管瘤样区的腔内衬细胞E-cadherin、β-catenin和p120ctn均呈胞质胞膜阳性表达。8例肺炎性假瘤中增生的Ⅱ型肺泡细胞E-cadherin、β-catenin和p120ctn表达与PSH中立方细胞的表达情况相同。结论PSH中的立方细胞可能是增生的Ⅱ型肺泡细胞,而多角形细胞为肿瘤的实质细胞且缺乏分化成熟的上皮细胞所具有的E-cadherin/catenin复合体。血管瘤样区的腔内衬细胞是与立方细胞相同的上皮细胞而非血管内皮细胞。
