Impact of primary percutaneous coronary intervention on ST-segment elevation myocardial infarction patients:A comprehensive analysis

BACKGROUND Myocardial infarction,particularly ST-segment elevation myocardial infarction(STEMI),is a key global mortality cause.Our study investigated predictors of mortality in 96 STEMI patients undergoing primary percutaneous coronary intervention at Erbil Cardiac Center.Multiple factors were identified influencing in-hospital mortality.Significantly,time from symptom onset to hospital arrival emerged as a decisive factor.Consequently,our study hypothesis is:"Reducing time from symptom onset to hospital arrival significantly improves STEMI prognosis."AIM To determine the key factors influencing mortality rates in STEMI patients.METHODS We studied 96 consecutive STEMI patients undergoing primary percutaneous coronary intervention(PPCI)at the Erbil Cardiac Center.Their clinical histories were compiled,and coronary evaluations were performed via angiography on admission.Data included comorbid conditions,onset of cardiogenic shock,complications during PPCI,and more.Post-discharge,one-month follow-up assessments were completed.Statistical significance was set at P<0.05.RESULTS Our results unearthed several significant findings.The in-hospital and 30-d mortality rates among the 96 STEMI patients were 11.2%and 2.3%respectively.On the investigation of independent predictors of in-hospital mortality,we identified atypical presentation,onset of cardiogenic shock,presence of chronic kidney disease,Thrombolysis In Myocardial Infarction grades 0/1/2,triple vessel disease,ventricular tachycardia/ventricular fibrillation,coronary dissection,and the no-reflow phenomenon.Specifically,the recorded average time from symptom onset to hospital arrival amongst patients who did not survive was significantly longer(6.92±3.86 h)compared to those who survived(3.61±1.67 h),P<0.001.These findings underscore the critical role of timely intervention in improving the survival outcomes of STEMI patients.CONCLUSION Our results affirm that early hospital arrival after symptom onset significantly improves survival rates in STEMI patients,highlighting the critical need for prompt intervention.

Energy Transfer Mechanism and Probability Analysis of Submarine Pipe Laterally Impacted by Dropped Objects

Energy transfer ratio is the basic-factor affecting the level of pipe damage during the impact between dropped object and submarine pipe. For the purpose of studying energy transfer and damage mechanism of submarine pipe impacted by dropped objects, series of experiments are designed and carried out. The effective yield strength is deduced to make the quasi-static analysis more reliable, and the normal distribution of energy transfer ratio caused by lateral impact on pipes is presented by statistic analysis of experimental results based on the effective yield strength, which provides experimental and theoretical basis for the risk analysis of submarine pipe system impacted by dropped objects. Failure strains of pipe material are confirmed by comparing experimental results with finite element simulation. In addition, impact contact area and impact time are proved to be the major influence factors of energy transfer by sensitivity analysis of the finite element simulation.

Analysis of hydrogeolgical characteristics and water environmental impact pathway of typical shale gas exploration and development zones in Sichuan Basin, China

Studying the influence of shale gas exploration and development on groundwater environment is the basis of guiding water environment protection in the process of shale gas exploration and development.Groundwater environmental pollution is concealed,complex and persistent.Once it is difficult to control the pollution,the current commercial shale gas development zones in Sichuan Basin that are mostly located in karst areas and highly sensitive to groundwater will be vulnerable to the impact of shale gas exploration and development.Based on the hydrogeological conditions of shale gas exploration and development area and combined with engineering analysis of exploration and development,various risk pathways that may affect the groundwater environment during process of shale gas exploration,mining well construction,mining operations and other stages were identified in this paper.Some existing risk pathways were proved by verification of typical areas and should not be ignored.Based on the actual situation of typical areas,the countermeasures of groundwater environmental protection in the process of shale gas exploration and development in karst areas were discussed.It is believed that the groundwater environment can be better protected by strengthening administration,research and application of new technologies,precise design,hydrogeological conditions,and research and feedback of groundwater environmental protection.

Dynamic impact experiment and response characteristics analysis for 1:2 reduced-scale model of hydraulic support

It is significant to research the impact resistance properties of hydraulic support due to its key support role in the fully mechanized mining face.However,it is difficult for the entire hydraulic support to implement the impact experiment underground and analyze the response characteristic.Therefore,a dynamic impact experiment for the entire hydraulic support was proposed in this paper,where a 1:2 reducedscale model of hydraulic support was designed and its response characteristics under dynamic impact load were analyzed.Firstly,a comprehensive monitoring scheme was proposed to achieve an effective monitoring for dynamic response of hydraulic support.Secondly,a multi-scale impact experiment was carried out for the entire hydraulic support and dynamic behaviors of hydraulic support under the multi-scale impact load were revealed by experimental data.Then a dynamic impact experiment of the entire hydraulic support was simulated in ADAMS with the same experiment conditions,and the experimental and simulation data were verified mutually.Finally,the characteristics of energy conversion and dissipation of the entire experiment system after impact were analyzed.The experiment results showed that the impact resistance properties of hydraulic support largely depended on the initial support conditions and different vertical rigidities affected energy distribution proportion of the entire support system.

Numerical Analysis of Hydrodynamic Pressure Induced by Fluid-Solid Impact

As a further development of the authors' work (Huang and Qian, 1993), in this paper a new numerical method based on the time domain boundary element technique is proposed for solving fluid-solid coupling problems, in which a rigid body impacts normally on the calm surface of a half-space fluid. A fundamental solution to the half-space potential flow problem is first derived with the method of images. Then, an equivalent boundary integral equation in the Laplace transform domain is established by means of Green's second identity. Through the inverse Laplace transform and discretization in both time and boundary of the fluid region, the numerical calculation for the problem under consideration has been carried out. Several examples demonstrate that the present method is more efficient than existing ones, from which it is also seen that the shape of the impacting body has a considerable effect on the total impact force.

Numerical and experimental analysis of the closed-cell aluminium foam under low velocity impact using computerized tomography technique

In the present work, the response of closed-cell aluminum foams under low-velocity impact has been studied numerically and experimentally. Computerized tomography is employed to access three-dimensional (3D) microstructure of the closed-cell aluminum foam. Effective parameters including foam density and the velocity of impactor on foam dynamic behavior are investigated. In order to show the validity and accuracy of results, some static experiments and low-velocity impact tests have been conducted. Results in dicate a remarkable agree me nt between the simulation and experimental data. Moreover, the results show that by increasing the density of foam samples, the highest difference between numerical and experimenidi results for peak stress and absorbed energy are 35.9% and 6.9%, respectively, which is related to the highest density. For impact velocities ranging from 3.1 to 4.2 m/s, the maximum discrepancy in peak stress and absorbed energy occur at an inipact velocity of 3.1 m/s in which corresponding errors are 33.3% and 6.6%, respectively. For the impact velocity of 40 m/s, the highest increase in peak stress and absorbed energy are 667.9% and 370.3% associated with the density of 0.5 and 0.3 g/cm^3, respectively.

An efficient formulation based on the Lagrangian method for contact–impact analysis of flexible multi-body system

In this paper,an efficien formulation based on the Lagrangian method is presented to investigate the contact–impact problems of f exible multi-body systems.Generally,the penalty method and the Hertz contact law are the most commonly used methods in engineering applications.However,these methods are highly dependent on various non-physical parameters,which have great effects on the simulation results.Moreover,a tremendous number of degrees of freedom in the contact–impact problems will influenc thenumericalefficien ysignificantl.Withtheconsideration of these two problems,a formulation combining the component mode synthesis method and the Lagrangian method is presented to investigate the contact–impact problems in fl xible multi-body system numerically.Meanwhile,the finit element meshing laws of the contact bodies will be studied preliminarily.A numerical example with experimental verificatio will certify the reliability of the presented formulationincontact–impactanalysis.Furthermore,aseries of numerical investigations explain how great the influenc of the finit element meshing has on the simulation results.Finally the limitations of the element size in different regions are summarized to satisfy both the accuracy and efficien y.

Analysis on the Impact of Facility Agriculture Development on Climate Change in Weifang

[Objective] The research aimed to study the influence of facility agriculture development on the climate variation in Weifang. [Method] Shouguang was selected as the representative station of greenhouse shed planting zone. By using the precipitation, temperature and relative humidity, etc. in Weifang City during 1961-2010, the climatic variation situations in the whole city and the greenhouse shed planting zone were analyzed. The variation trend and evolution characteristics of climate in the different seasons before and after the facility agriculture plantation were contrasted and analyzed. [Result] The annual rainfall and relative humidity presented the declining trend in the whole city in recent 50 years. The annual average, maximum and minimum temperatures all presented the rising trend. Since the large-scale plantation of greenhouse shed, the declining range of annual rainfall in the greenhouse shed planting zone was lower than that in the whole city, and the declining range of relative humidity was obviously higher than that in the whole city. The rising ranges of annual average, maximum and minimum temperatures were higher than that in the whole city. [Conclusion] The research provided the theory basis for the development of facility agriculture.

Calculation of Ecological Footprint Based on Modified Method and Quantitative Analysis of Its Impact Factors——A Case Study of Shanghai

Ecological footprint(EF) has attracted much attention internationally as a potential indicator for sustainable development.In China,EF has also gained recognition in related fields and disciplines.Moreover,some scholars in these fields have proposed alternative methods to calculate EF and have made some progress.This paper,therefore,begins with the introduction and development of EF in China.However,the established methods of EF calculation hold some limitations,such as indicator variance and result abnormality.In order to resolve those problems,the authors make a further modification considering the demand of EF as a comprehensive indicator:1) More accurate analysis has been done to divide EF into several parts:imported EF,exported EF,and producible EF,which is the solution to the problem of abnormality in original EF results and can explain abnormal phenomena reasonably.2) Considering the actual situa-tion of Shanghai,amended equivalence factor is brought forward and a matrix is formed with equivalence factors.The measure can reduce the deviation between the fact and the results.3) The calculation compares local yield with global average yield to analyze the effects of yields.And based on local yields in different years,the results are more accurate.Finally,the calculation method is applied to calculating EF of Shanghai from 1980 to 2003,and the subsequent detailed analysis is presented.Available data and results suggest a statistically significant correlation coefficient between EF and GDP,population density and urbanization level.Through analyzing the process of calculating EF and its results,it can be seen that EF,as a macro-indicator,can not exactly indicate whether development within a region can meet the re-quests of sustainable development,which can be explained by the fact that the result of EF is impacted greatly by sub-jective factors including national policy,available technology,population,etc.Nevertheless,EF can demonstrate,at least to some degree,the regional status in terms of resources and energy consumption,as well as developmental potential.The calculation of EF,therefore,deserves further research to achieve more far-reaching significance in application.

Prognostic impact of the red cell distribution width in esophageal cancer patients: A systematic review and meta-analysis

AIM To clarify the previous discrepant conclusions, we performed a meta-analysis to evaluate the prognostic value of red cell distribution width(RDW) in esophageal cancer(EC). METHODS We searched the PubM ed, EMBASE, Web of Science and Cochrane Library databases to identify clinical studies, followed by using STATA version 12.0 for statistical analysis. Studies that met the following criteria were considered eligible:(1) Studies including EC patients who underwent radical esophagectomy;(2) studies including patients with localized disease without distant metastasis;(3) studies including patients without preoperative neoadjuvant therapy;(4) studies including patients without previous antiinflammatory therapies and with available preoperative laboratory outcomes;(5) studies reporting association between the preoperative RDW and overall survival(OS)/disease-free survival(DFS)/cancer-specific survival(CSS); and(6) studies published in English.RESULTS A total of six articles, published between 2015 and 2017, fulfilled the selection criteria in the end. Statistical analysis showed that RDW was not associated with the prognosis of EC patients, irrespective of OS/CSS [hazard ratio(HR) = 1.27, 95% confidence interval(CI): 0.97-1.57, P = 0.000] or DFS(HR = 1.42, 95%CI: 0.96-1.88, P = 0.000). Subgroup analysis indicated that elevated RDW was significantly associated with worse OS/CSS of EC patients when RDW > 13%(HR = 1.45, 95%CI: 1.13-1.76, P = 0.000), when the patient number ≤ 400(HR = 1.45, 95%CI: 1.13-1.76, P = 0.000) and when the study type was retrospective(HR = 1.42, 95%CI : 1.16-1.69, P = 0.000).CONCLUSION Contrary to our general understanding, this meta-analysis revealed that RDW cannot serve as an indicator of poor prognosis in patients with EC. However, it may still be a useful predictor of unfavorable prognosis using an appropriate cut-off value.

Dynamic impact properties of deep sandstone under thermal-hydraulicmechanical coupling loads

The deep rock mass within coal mines situated in a challenging environment are characterized by high ground stress,high geotemperature,high osmotic water pressure,and dynamic disturbances from mechanical excavation.To investigate the impact of this complex mechanical environment on the dynamic characteristics of roof sandstone in self-formed roadways without coal pillars,standard specimens of deep sandstone from the 2611 upper tunnel working face of the Yongmei Company within the Henan Coal Chemical Industry Group in Henan,China were prepared,and an orthogonal test was designed.Using a self-developed geotechnical dynamic impact mechanics test system,triaxial dynamic impact tests under thermal-hydraulicmechanical coupling conditions were conducted on deep sandstone.The results indicate that under high confining pressure,deep sandstone exhibits pronounced brittle failure at low temperatures,with peak strength gradually decreasing as temperature and osmotic water pressure increase.Conversely,under low confining pressure and low temperature,the brittleness of deep sandstone weakens gradually,while ductility increases.Moreover,sandstone demonstrates higher peak strength at low temperatures under high axial pressure conditions,lower peak strength at high temperatures,and greater strain under low axial pressure and high osmotic water pressure.Increases in impact air pressure and osmotic water pressure have proportionally greater effects on peak stress and peak strain.Approximately 50%of the input strain energy is utilized as effective energy driving the sandstone fracture process.Polar analysis identifies the optimal combination of factors affecting the peak stress and peak strain of sandstone.Under the coupling effect,intergranular and transgranular fractures occur within the sandstone.SEM images illustrate that the damage forms range from minor damage with multiple fissures to extensive fractures and severe fragmentation.This study elucidates the varied dynamic impact mechanical properties of deep sandstones under thermal-hydraulic-mechanical coupling,along with multifactor analysis methods and their optimal factor combinations.

Analysis of tritium production in a 2 MW liquid-fueled molten salt experimental reactor and its environmental impact

Tritium release is one of the most concerning topics in nuclear power plants. Here, the tritium production in a 2 MW liquid-fueled molten salt experimental reactor(TMSR-LF1) was calculated by ORIGEN-S with an updated cross-section library generated by TRITON in SCALE 6.1.3 code system. The results show that the tritium production rate and normalized tritium production rate of TMSR-LF1 are 8.90x10^(11)Bq/day and4.45x10^(11)Bq/(MW day), respectively. The environmental impact of tritium was analyzed via PC-CREAM 08 with an assumed 36 % release rate of tritium referring to the molten salt reactor experiment. During normal operations, the maximum tritium concentration is 1.4 Bq/m^3 under normal condition, and the corresponding individual dose to the public is about 1 μSv/a; under extreme conditions, the maximum concentration and corresponding individual doses are 11.8 Bq/m^3 and 9 μSv/a, respectively.Ingestion is the main exposure pathway and accounts for62 % of the total dose. Of this, 35 % is from organically bound tritium.

A Case Study of Impact of FY-2C Satellite Data in Cloud Analysis to Improve Short-Range Precipitation Forecast

Chinese FengYun-2C(FY-2C) satellite data were combined into the Local Analysis and Prediction System(LAPS) model to obtain three-dimensional cloud parameters and rain content. These parameters analyzed by LAPS were used to initialize the Global/Regional Assimilation and Prediction System model(GRAPES) in China to predict precipitation in a rainstorm case in the country. Three prediction experiments were conducted and were used to investigate the impacts of FY-2C satellite data on cloud analysis of LAPS and on short range precipitation forecasts. In the first experiment, the initial cloud fields was zero value. In the second, the initial cloud fields were cloud liquid water, cloud ice, and rain content derived from LAPS without combining the satellite data. In the third experiment, the initial cloud fields were cloud liquid water, cloud ice, and rain content derived from LAPS including satellite data. The results indicated that the FY-2C satellite data combination in LAPS can show more realistic cloud distributions, and the model simulation for precipitation in 1–6 h had certain improvements over that when satellite data and complex cloud analysis were not applied.

Methods for Progressive Collapse Analysis of Building Structures Under Blast and Impact Loads

Progressive collapse of building structures under blast and impact loads has attracted great attention all over the world. Progressive collapse analysis is essential for an economic and safe design of building structures against progressive collapse to blast and impact loads. Because of the catastrophic nature of progressive collapse and the potentially high cost of constructing or retrofitting buildings to resist it, it is imperative that the progressive collapse analysis methods be reliable. For engineers, their methodology to carry out progressive collapse evaluation need not only be accurate and concise, but also be easily used and works fast. Thus, many researchers have been spending lots of effort in developing reliable, efficient and straightforward progressive collapse analysis methods recently. In the present paper, current progressive collapse analysis methods available in the literature are reviewed. Their suitability, applicability and reliability are discussed. Our recent proposed new method for progressive collapse analysis of reinforced concrete frames under blast loads is also introduced.

Coupled DEM-FDM analyses of the effects of falling rock’s shape and impact angle on response of granular cushion and rock shed

Rock shed is an effective protection measure against rockfall.To investigate the influences of falling rock’s shape and impact angle on the impact effect of the cushioned rock shed,a modeling approach for a rock shed with a cushion layer using PFC-FLAC.The granular cushion is modeled as an aggregate of discrete non-cohesion particles,while the concrete plate and the beam are modeled as zones.The falling rock with different sphericities and impact angles is modeled as a rigid assembly.The numerical model is validated by comparing the simulation results with experimental and numerical results from previous literature.This model is applied to analyze the effects of rock shape and impact angle on the dynamic interaction effects between falling rock and cushioned rock shed,including the impact force,transmitted bottom force,penetration depth,and plate deflection.The numerical results show that the variation in the falling rock’s shape has different effects on the falling rock with different impact angles.These findings could support rock shed design by revealing the limitations of the assumptions in the past research,which may result in unsafe rock sheds for some rockfall cases.

The impact analysis of policy events on China's carbon market

This paper interrogates the impact of policy events on the efficiency of carbon market in China.The analysis covers five piloting emission trading schemes(Beijing, Shanghai, Guangdong,Shenzhen and Hubei), particularly focusing on Guangdong pilot for its weak form efficiency and the richness of policy events. Twenty-five policy events between 2014 and 2016 are categorized into seven groups. The efficiency test indicates that only Guangdong ETS has reached weak form efficiency. After exploring the policy events occurred in Guangdong ETS, it finds that although a clear long-term climate policy has been set up over the country, China's carbon market still has a conservative risk appetite and its governing institutions still needs further development. The policy makers need to be aware of and avoid the negative impacts of policy events to the market evolvement, by introducing effective consultancy process with the stakeholders and nurturing market expectations in the long run. We also find that events like allowance auctions have considerably less impacts than previously expected and argue that auction approach should be considered a preferable option over a free allocation system in the future policy design.

A Two-folded Impact Analysis of Schema Changes on Database Applications

Database applications are becoming increasingly popular, mainly due to the advanced data management facilities that the underlying database management system offers compared against traditional legacy software applications. The interaction, however, of such applications with the database system introduces a number of issues, among which, this paper addresses the impact analysis of the changes performed at the database schema level. Our motivation is to provide the software engineers of database applications with automated methods that facilitate major maintenance tasks, such as source code corrections and regression testing, which should be triggered by the occurrence of such changes. The presented impact analysis is thus two-folded： the impact is analysed in terms of both the affected source code statements and the affected test suites concerning the testing of these applications. To achieve the former objective, a program slicing technique is employed, which is based on an extended version of the program dependency graph. The latter objective requires the analysis of test suites generated for database applications, which is accomplished by employing testing techniques tailored for this type of applications. Utilising both the slicing and the testing techniques enhances program comprehension of database applications, while also supporting the development of a number of practical metrics regarding their maintainability against schema changes. To evaluate the feasibility and effectiveness of the presented techniques and metrics, a software tool, called DATA, has been implemented. The experimental results from its usage on the TPC-C case study are reported and analysed.

Analysis on the Impact of Mountain Climate on Tourism Development of Ziyuan County,Guangxi

Ziyuan County is in the northeast mountainous area of Guangxi,with rich tourism resources. The research on tourism climate resources of Ziyuan County could provide reference for rational development of mountain tourism in the county. Through on-the-spot investigation,the local tourism and climate data were collected,and the evolution of climate data was analyzed,and the influence of climate on tourism development was studied. It can see snow in winter of Ziyuan County,and there is not high temperature in summer,where is the best place for summer vacation.Due to typical Danxia landform,beautiful mountain ecology and comfortable climate condition,Ziyuan has become the preferred leisure vacation destination of Guilin. It should rationally utilize meteorological service information to effectively avoid the meteorological disasters,and use the climate resource advantage of mountainous area to develop Ziyuan County's tourism.

A 3-D DDA damage analysis of brick masonry buildings under the impact of boulders in mountainous areas

In mountainous areas, geological disasters carrying large boulders can cause severe damage to the widely used masonry buildings due to the high impact forces. To better understand the damage of brick masonry buildings under the impact of boulders, a "block-joint" model is developed using threedimensional discontinuous deformation analysis(3-D DDA) to simulate the behaviour of the "brick-mortar" structure. The "block-joint" model is used to capture not only the large displacement and deformation of individual bricks but also the large-scale sliding and opening along the mortar between the bricks. The linear elastic constitutive model is applied to account for the non-plastic deformation behaviour of brick materials. Furthermore, the mechanical characteristics of the mortar are represented using the Mohr-Coulomb and Drucker-Prager criteria. To propose safe structural design schemes and effective reinforcement for brick masonry buildings, seven construction techniques are considered, includingdifferent grades of brick and mortar, effective shear areas and reinforced members. The proposed 3-D DDA model is used to analyse the velocity distribution and the key point displacements of the brick masonry building under the impact of boulders. The results show that upgrading the brick and mortar, increasing the wall thickness, making full use of the wall thickness, and adding a circular beam and structural column are very effective approaches for improving the impact resistance of brick masonry buildings.

LAPLACE TRANSFORM-BOUNDARY ELEMENT COUPLING METHOD FOR VISCOUS FLUIDSTRUCTURE IMPACT ANALYSIS

Based on linearized 2-D Navier-Stokes equation, a Laplacetransform-boundary element coupling method for viscousfluid-structure impact analysis is proposed. Under assumption ofincompressibility for the fluid, the corresponding equivalentboundary integral equation in terms of the potential function andstream function is first established by Lamb's transform in theLaplace transform domain.