Protective effect of Solanum Nigrum Linn green fruit ethanolic extract on alcoholic liver injury in mice

Alcoholic liver injury is a liver disease caused by excessive alcohol consumption,which can lead to chronic liver disease death.Solanum Nigrum Linn taste bitter,cold,has the effect of clearing heat and detoxification,promoting blood and detumescence.Solanum Nigrum Linn fruit contains a variety of antioxidant enzymes,can remove the body produced by aerobic metabolism harmful substances.In this paper,a model of alcohol-induced liver injury in C57BL/6 mice was established to evaluate the protective effect of Solanum Nigrum Linn green fruit(SNGF)ethanolic extract on alcohol-induced liver injury.H&E staining and oil red O(ORO)staining showed that hepatic lobules were clearly demarcated,vacuoles were significantly reduced and lipid droplets were reduced in SNGF ethanolic extract treatment group.Serum levels of TC,TG,LDH,TBA,AKP,ALT and AST were decreased in the SNGF ethanolic extract treatment group,and SNGF ethanolic extract could clear reactive oxygen species(ROS)in time.MDA content was signifi cantly decreased after SNGF ethanolic extract treatment,while superoxide dismutase(SOD)and GSH-Px contents were increased after SNGF ethanolic extract treatment.These results suggest that SNGF ethanolic extract has a protective effect on alcohol-induced liver injury.

龙葵绿果对小菜蛾的杀虫活性初探

采用浸渍法,测定了龙葵绿果乙醇提取物和石油醚、氯仿、乙酸乙酯、正丁醇、水5种不同极性溶剂萃取物对小菜蛾的触杀活性。结果表明:95%乙醇提取物对小菜蛾有较高的触杀活性,而且随着提取物质量浓度的增大和处理时间的延长,小菜蛾的校正死亡率升高。质量浓度为50.00g/L时,72h的校正死亡率达到97.62%,LC50值4.798g/L。5种萃取物对小菜蛾杀虫活性主要集中在石油醚和氯仿萃取部分,石油醚和氯仿萃取物72h的校正死亡率分别为83.33%和73.33%。