Oxidative stress has been considered as a major cause of cellular injuries in a variety of clinical abnormalities, especially prominent in neural diseases. One of the usable ways to prevent the reactive oxygen species...Oxidative stress has been considered as a major cause of cellular injuries in a variety of clinical abnormalities, especially prominent in neural diseases. One of the usable ways to prevent the reactive oxygen species (ROS)-mediated cellular injury is dietary or pharmaceutical augmentation of some free radical scavenger. Water-soluble amino-fullerene is a novel compound that behaves as a free radical scavenger with excellent biology consistent. In the present study, we have synthesized and characterized a novel cystine C60 derivative for the first time, and investigated the effects on hydrogen peroxide-induced oxidative stress and apoptotic death in cultured rat pheochromocytoma (PC12) cells. PC12 cells treated with hydrogen peroxide underwent apoptotic death as determined by MTT, PI/Hoechst 33342 staining and flow cytometry analysis. These results suggested that cystine C60 derivative has the potential to prevent oxidative stress-induced cell death and has no evident toxicity.展开更多
While WCl_6-Ph_4Sn fails to polymerize 1-phenyl-1-propyne (PP) at room temperature, highmolecular weight (M_w up to 410× 10~3) polymers are obtained in high yields (up to 80%) when thepolymerizations of PP are ca...While WCl_6-Ph_4Sn fails to polymerize 1-phenyl-1-propyne (PP) at room temperature, highmolecular weight (M_w up to 410× 10~3) polymers are obtained in high yields (up to 80%) when thepolymerizations of PP are carried out in the presence of C_(60) using the W catalyst under the same conditions.The polymers are soluble in common organic solvents such as THF, chloroform, and toluene. Molecularstructures of the polymers are characterized by FT-IR, UV, NMR, GPC and XRD, and it is found that C_(60) iscopolymerized with PP. Thus C_(60) plays the dual roles of comonomer and cocatalyst in the polymerizationreaction. C_(60) contents of the copolymers can be easily changed by varying the C_(60) amounts in the feedmixtures. The copolymers effectively limit strong 532 nm laser pulses, whose limiting performance issuperior to that of parent C_(60).展开更多
Photoinduced electron transfer processes between fullerenes (C60 / C70) and N, N, N, N tetra - ( p-methylphenyl ) - 4, 4 diamino - 1, 1- diphenyl ether ( TPDAE ) have been studied by nanosecond laser flash photolysis....Photoinduced electron transfer processes between fullerenes (C60 / C70) and N, N, N, N tetra - ( p-methylphenyl ) - 4, 4 diamino - 1, 1- diphenyl ether ( TPDAE ) have been studied by nanosecond laser flash photolysis. Quantum yields and rate constants of electron transfer from TPDAE to excited triplet state of fullerenes (C60 / C70 ) in benzonitrile have been evaluated by observing the transient absorption bands in the near-IR region where the excited triplet state, radical anion of fullerenes ( C60 / C70 ) and radical cations of TPDAE appear.展开更多
Water-soluble b-alanine C60 adducts were synthesized, and the scavenging ability to superoxygen anion radical O2- and hydroxyl radical.OH were studied by autoxidation of pyrogallol and chemiluminescence, respectively....Water-soluble b-alanine C60 adducts were synthesized, and the scavenging ability to superoxygen anion radical O2- and hydroxyl radical.OH were studied by autoxidation of pyrogallol and chemiluminescence, respectively. It was found thatβ-alanine C60 adducts showed an excellent efficiency in eliminating superoxygen anion radical and hydroxyl radical. The 50% inhibition concentration (IC50) for superoxygen anion radical and hydroxyl radical were 0.15 mg/mL and 0.048 mg/mL, respectively. The difference should be mainly attributed to the different scavenging mechanisms.展开更多
C60 is successfully solubilized in micelle of six kinds of surfactants and UV/Vis spectra ofC60 in micellar system are studied. It is found that Brij-35 is the most efficient surfactant forsolubilization of C60 and th...C60 is successfully solubilized in micelle of six kinds of surfactants and UV/Vis spectra ofC60 in micellar system are studied. It is found that Brij-35 is the most efficient surfactant forsolubilization of C60 and the possible states of C60 existed in surfactants are also studied.Experiments of surface tension show that the sites for solubilization of C60 not only depend on thesorts of surfactants but also on their structures.展开更多
While WC_16-Ph_4Sn is a poor catalyst for the polymerization of l-phenyl-butyne (PB) at room temperature, it effectively polymerizes PB in the presence of C_(60), giving high molecular weight polymers in high yields. ...While WC_16-Ph_4Sn is a poor catalyst for the polymerization of l-phenyl-butyne (PB) at room temperature, it effectively polymerizes PB in the presence of C_(60), giving high molecular weight polymers in high yields. The polymer is soluble in THF and chloroform and spectroscopic analysis reveals that Coo has copolymerized with PB. Thus, C_(60) plays dual roles of comonomer and cocatalyst in the acetylene polymerization. The copolymers strongly attenuate 532-nm laser pulses, whose limiting performance is superior to that of parent C_(60)展开更多
Both enantiomers R-1 and S-1 of a chiral C60 derivative were synthesized by the reactions of C60 with 1, 1'-bi-2-naphthol bis(azidoacetates) and characterized by FD-MS, fT-IR,1H NMR, 13C NMR, UV-VIS, CD spectra.
The electrochemical properties of a new derivative of C60 were investigated by cyclic voltammetry. It was found that the derivative was reduced at a more positive potential than C60,reflecting its significance to acce...The electrochemical properties of a new derivative of C60 were investigated by cyclic voltammetry. It was found that the derivative was reduced at a more positive potential than C60,reflecting its significance to accept electron easily. Its NIR characteristic absorption bands ofmonoanion and dianion were also obtained.展开更多
The states of small molecule H2 and N2 in the Coo cage have been studied. It is shown that the molecular stable configUrations of the caged states exhibits little change compared with the free states, but the bond int...The states of small molecule H2 and N2 in the Coo cage have been studied. It is shown that the molecular stable configUrations of the caged states exhibits little change compared with the free states, but the bond intensities of the caged states have become much stronger.展开更多
C_(60) and C_(70) single crystals free from solvent contamination grew from their vapour. Large C_(60) crystals up to a size of about 5 mm × 3 mm × 3 mm and C_(70) crystals about 1 mm × 1 mm × ...C_(60) and C_(70) single crystals free from solvent contamination grew from their vapour. Large C_(60) crystals up to a size of about 5 mm × 3 mm × 3 mm and C_(70) crystals about 1 mm × 1 mm × 1 mm were obtained. C_(60) crystals with fee structure showed two types of morphological faces, namely {111} and {100 },frequently with twinning on {111} face. C_(70) crystals obtained have a hop structure with a = 10. 1 andc=16. 7 DSC and X-ray diffraction analysis indicated that C(70) crystal underwent phase transition below 100 ℃ Morphological observation suggests that the growth of C(60) and C(70) single crystals is based on layer spreading mechanism.展开更多
Different C_(60) crystals were synthesized by precipitation from a mixture of the good solvent m-xylene and the poor solvent isopropyl alcohol.The samples were characterized by scanning electron microscopy(SEM),Raman ...Different C_(60) crystals were synthesized by precipitation from a mixture of the good solvent m-xylene and the poor solvent isopropyl alcohol.The samples were characterized by scanning electron microscopy(SEM),Raman spectroscopy,thermogravimetric analysis,and high resolution transmission electron microscope(HRTEM).We found that the morphologies and sizes of the samples could be controlled by adjusting the volume ratio between the good and poor solvents.Especially,an unexpected short flower column-like crystal was synthesized at low ratios(from 1:6 to 1:12).Room temperature photoluminescence(PL)and HRTEM studies of the C_(60) crystal samples reveal that the PL efficiency of the crystals decreases with increasing crystalline order and that the disordered C_(60) crystals synthesized at the ratio of 1:2 show 10 times higher PL efficiency than that of pristine C_(60).The mechanism of the growth process of these C_(60) crystals was also studied by replacing the good solvents m-xylene with toluene and mesitylene.展开更多
A simple new method for the syntheses of a highly soluble noncross linked C 60 styrene copolymers by means of lithium camphor initiated anionic polymerization reaction is demonstrated.
The scattering factor of C60 molecule have been calculated according toX-ray diffraction theory. By comparing it with the atomic scattering factor of carbon,it is found that the scattering factor of C60 molecule is a ...The scattering factor of C60 molecule have been calculated according toX-ray diffraction theory. By comparing it with the atomic scattering factor of carbon,it is found that the scattering factor of C60 molecule is a sine-oscillating attenuate finction of sinθ/λ depending on the direction of the incident beam, which is attenuatedmore quickly than that of single carbon atom. However, there is nO evident differencefor the different directions when 0.00≤sinθ/λ≤0.15.展开更多
Organic photovoltaic devices(OPVs) using chiral cyclohexene-fused [C_(60)]-fullerene derivatives that have(l)-menthyl ester moiety have been prepared and their properties evaluated as acceptor molecules with P3 HT pol...Organic photovoltaic devices(OPVs) using chiral cyclohexene-fused [C_(60)]-fullerene derivatives that have(l)-menthyl ester moiety have been prepared and their properties evaluated as acceptor molecules with P3 HT polymer: racemic cyclohexene-fused [C_(60)] fullenene,(RS)-(1 R,2 S,5 R)-2 a showed higher PCE(2.81%) than that of standard [C_(60)]-PCBM(2.64%) under the same analysis conditions. On the contrary, devices using chiral(R)-(1 R,2 S,5 R)-2 a and(S)-(1 R,2 S,5 R)-2 a, showed PCE as 1.08% and 1.10%, respectively. The main origin of the differences in PCE was found to be their poor Jsc values. The results indicate that the aggregation state might influence the interaction state with P3 HT and impact the results of the OPV properties, Jsc values in particular.展开更多
The structure optimization was done at the PM3 and AMI levels forthe C60O3(6/6 addition) isomers generated by adding one oxygen atom to the most sta-ble C60O3 (6/6 addition). It is found that the most stable structure...The structure optimization was done at the PM3 and AMI levels forthe C60O3(6/6 addition) isomers generated by adding one oxygen atom to the most sta-ble C60O3 (6/6 addition). It is found that the most stable structures are those with threeoxygen atoms added on the adjacent 6/6 bonds of C60 as closely as possible but not onthe same six-ring. We calculated the electronic spectra of the optimized structures byuse of INDO/CI method.展开更多
文摘Oxidative stress has been considered as a major cause of cellular injuries in a variety of clinical abnormalities, especially prominent in neural diseases. One of the usable ways to prevent the reactive oxygen species (ROS)-mediated cellular injury is dietary or pharmaceutical augmentation of some free radical scavenger. Water-soluble amino-fullerene is a novel compound that behaves as a free radical scavenger with excellent biology consistent. In the present study, we have synthesized and characterized a novel cystine C60 derivative for the first time, and investigated the effects on hydrogen peroxide-induced oxidative stress and apoptotic death in cultured rat pheochromocytoma (PC12) cells. PC12 cells treated with hydrogen peroxide underwent apoptotic death as determined by MTT, PI/Hoechst 33342 staining and flow cytometry analysis. These results suggested that cystine C60 derivative has the potential to prevent oxidative stress-induced cell death and has no evident toxicity.
基金This work was in part supported by the Hong Kong Research Grants Council(HKUST6062/98P and DAG96/97 SC11).
文摘While WCl_6-Ph_4Sn fails to polymerize 1-phenyl-1-propyne (PP) at room temperature, highmolecular weight (M_w up to 410× 10~3) polymers are obtained in high yields (up to 80%) when thepolymerizations of PP are carried out in the presence of C_(60) using the W catalyst under the same conditions.The polymers are soluble in common organic solvents such as THF, chloroform, and toluene. Molecularstructures of the polymers are characterized by FT-IR, UV, NMR, GPC and XRD, and it is found that C_(60) iscopolymerized with PP. Thus C_(60) plays the dual roles of comonomer and cocatalyst in the polymerizationreaction. C_(60) contents of the copolymers can be easily changed by varying the C_(60) amounts in the feedmixtures. The copolymers effectively limit strong 532 nm laser pulses, whose limiting performance issuperior to that of parent C_(60).
文摘Photoinduced electron transfer processes between fullerenes (C60 / C70) and N, N, N, N tetra - ( p-methylphenyl ) - 4, 4 diamino - 1, 1- diphenyl ether ( TPDAE ) have been studied by nanosecond laser flash photolysis. Quantum yields and rate constants of electron transfer from TPDAE to excited triplet state of fullerenes (C60 / C70 ) in benzonitrile have been evaluated by observing the transient absorption bands in the near-IR region where the excited triplet state, radical anion of fullerenes ( C60 / C70 ) and radical cations of TPDAE appear.
文摘Water-soluble b-alanine C60 adducts were synthesized, and the scavenging ability to superoxygen anion radical O2- and hydroxyl radical.OH were studied by autoxidation of pyrogallol and chemiluminescence, respectively. It was found thatβ-alanine C60 adducts showed an excellent efficiency in eliminating superoxygen anion radical and hydroxyl radical. The 50% inhibition concentration (IC50) for superoxygen anion radical and hydroxyl radical were 0.15 mg/mL and 0.048 mg/mL, respectively. The difference should be mainly attributed to the different scavenging mechanisms.
文摘C60 is successfully solubilized in micelle of six kinds of surfactants and UV/Vis spectra ofC60 in micellar system are studied. It is found that Brij-35 is the most efficient surfactant forsolubilization of C60 and the possible states of C60 existed in surfactants are also studied.Experiments of surface tension show that the sites for solubilization of C60 not only depend on thesorts of surfactants but also on their structures.
文摘While WC_16-Ph_4Sn is a poor catalyst for the polymerization of l-phenyl-butyne (PB) at room temperature, it effectively polymerizes PB in the presence of C_(60), giving high molecular weight polymers in high yields. The polymer is soluble in THF and chloroform and spectroscopic analysis reveals that Coo has copolymerized with PB. Thus, C_(60) plays dual roles of comonomer and cocatalyst in the acetylene polymerization. The copolymers strongly attenuate 532-nm laser pulses, whose limiting performance is superior to that of parent C_(60)
文摘Both enantiomers R-1 and S-1 of a chiral C60 derivative were synthesized by the reactions of C60 with 1, 1'-bi-2-naphthol bis(azidoacetates) and characterized by FD-MS, fT-IR,1H NMR, 13C NMR, UV-VIS, CD spectra.
文摘The electrochemical properties of a new derivative of C60 were investigated by cyclic voltammetry. It was found that the derivative was reduced at a more positive potential than C60,reflecting its significance to accept electron easily. Its NIR characteristic absorption bands ofmonoanion and dianion were also obtained.
文摘The states of small molecule H2 and N2 in the Coo cage have been studied. It is shown that the molecular stable configUrations of the caged states exhibits little change compared with the free states, but the bond intensities of the caged states have become much stronger.
文摘C_(60) and C_(70) single crystals free from solvent contamination grew from their vapour. Large C_(60) crystals up to a size of about 5 mm × 3 mm × 3 mm and C_(70) crystals about 1 mm × 1 mm × 1 mm were obtained. C_(60) crystals with fee structure showed two types of morphological faces, namely {111} and {100 },frequently with twinning on {111} face. C_(70) crystals obtained have a hop structure with a = 10. 1 andc=16. 7 DSC and X-ray diffraction analysis indicated that C(70) crystal underwent phase transition below 100 ℃ Morphological observation suggests that the growth of C(60) and C(70) single crystals is based on layer spreading mechanism.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11504269 and 11504267)Tianjin Natural Science Foundation(Grant No.20JCQNJC00660)the Program for Innovative Research in University of Tianjin(Grant No.TD13-5077).
文摘Different C_(60) crystals were synthesized by precipitation from a mixture of the good solvent m-xylene and the poor solvent isopropyl alcohol.The samples were characterized by scanning electron microscopy(SEM),Raman spectroscopy,thermogravimetric analysis,and high resolution transmission electron microscope(HRTEM).We found that the morphologies and sizes of the samples could be controlled by adjusting the volume ratio between the good and poor solvents.Especially,an unexpected short flower column-like crystal was synthesized at low ratios(from 1:6 to 1:12).Room temperature photoluminescence(PL)and HRTEM studies of the C_(60) crystal samples reveal that the PL efficiency of the crystals decreases with increasing crystalline order and that the disordered C_(60) crystals synthesized at the ratio of 1:2 show 10 times higher PL efficiency than that of pristine C_(60).The mechanism of the growth process of these C_(60) crystals was also studied by replacing the good solvents m-xylene with toluene and mesitylene.
文摘A simple new method for the syntheses of a highly soluble noncross linked C 60 styrene copolymers by means of lithium camphor initiated anionic polymerization reaction is demonstrated.
文摘The scattering factor of C60 molecule have been calculated according toX-ray diffraction theory. By comparing it with the atomic scattering factor of carbon,it is found that the scattering factor of C60 molecule is a sine-oscillating attenuate finction of sinθ/λ depending on the direction of the incident beam, which is attenuatedmore quickly than that of single carbon atom. However, there is nO evident differencefor the different directions when 0.00≤sinθ/λ≤0.15.
基金supported by a Grant-in-Aid for Scientific Research of the GSC Center of Tottori University from the Ministry of Education, Culture, Sports, Science and Technology of Japansupported by a fund for Environmental Research from Tottori Prefecture
文摘Organic photovoltaic devices(OPVs) using chiral cyclohexene-fused [C_(60)]-fullerene derivatives that have(l)-menthyl ester moiety have been prepared and their properties evaluated as acceptor molecules with P3 HT polymer: racemic cyclohexene-fused [C_(60)] fullenene,(RS)-(1 R,2 S,5 R)-2 a showed higher PCE(2.81%) than that of standard [C_(60)]-PCBM(2.64%) under the same analysis conditions. On the contrary, devices using chiral(R)-(1 R,2 S,5 R)-2 a and(S)-(1 R,2 S,5 R)-2 a, showed PCE as 1.08% and 1.10%, respectively. The main origin of the differences in PCE was found to be their poor Jsc values. The results indicate that the aggregation state might influence the interaction state with P3 HT and impact the results of the OPV properties, Jsc values in particular.
文摘The structure optimization was done at the PM3 and AMI levels forthe C60O3(6/6 addition) isomers generated by adding one oxygen atom to the most sta-ble C60O3 (6/6 addition). It is found that the most stable structures are those with threeoxygen atoms added on the adjacent 6/6 bonds of C60 as closely as possible but not onthe same six-ring. We calculated the electronic spectra of the optimized structures byuse of INDO/CI method.
