The wadi dahab delta is in a dry, arid coastal zone within Egypt’s south Sinai Peninsula’s eastern portion. The primary water source is the Quaternary coastal alluvial aquifer. The groundwater salinity varies from 8...The wadi dahab delta is in a dry, arid coastal zone within Egypt’s south Sinai Peninsula’s eastern portion. The primary water source is the Quaternary coastal alluvial aquifer. The groundwater salinity varies from 890to 8213 mg/L, with a mean value of 3417 mg/L. The dissolved major ions have been used to calculate the seawater mixing index(SWMI) using a linear equation that discriminates the groundwater mostly affected by water–rock interaction(SWMI 1>) and other samples mixed with Seawater(SWMI < 1). The isotopic composition of groundwater for specifically chosen groundwater samples ranges from-0.645‰ to +5.212‰ for δ^(18)O and from-9.582‰ to + 22.778‰ for δ^(2)H, where the seawater represented by a Red Sea water sample(δ^(18)O + 1.64‰-δ^(2)H + 9.80‰) and reject brine water are considerably enriched the isotopic groundwater values. The geochemical NETPATH model constrained by the dissolved significant ions, isotopes, and the rock aquifer forming minerals as phases indicate the mixing percent with the seawater ranges from 9% to 97% of seawater from 91% to 3% of original recharge water. According to the SEAWAT 3-D flow models, seawater has penetrated the Northeastern Dahab delta aquifer, with the intrusion zone extending1500 m inland. The salt dissolution, upwelling of saline water, recharge from the upstream mountain block, and seawater encroachment are the primary aspects contributing to the deterioration of groundwater quality. These findings may have significance for effective groundwater withdrawal management in arid locations worldwide with similar hydrogeological systems.展开更多
Appropriate drying process with optimized controlling of drying parameters plays a vital role in the improvement of the quality and performance of propellant products.However,few research on solvent transport dynamics...Appropriate drying process with optimized controlling of drying parameters plays a vital role in the improvement of the quality and performance of propellant products.However,few research on solvent transport dynamics within NC-based propellants was reported,and its effect on the evolution of mechanical properties was not interpreted yet.This study is conducted to gain a comprehensive understanding of hot-air drying for NC-based propellants and clarify the effect of temperature on solvent transport behavior and further the change of mechanical properties during drying.The drying kinetic curves show the drying time required is decreased but the steady solvent content is increased and the drying rate is obviously increased with the increase of hot-air temperatures,indicating hot-air temperatures have a significant effect on drying kinetics.A modified drying model was established,and results show it is more appropriate to describe solvent transport behavior within NC-based propellants.Moreover,two linear equations were established to exhibit the relationship between solvent content and its effect on the change of tensile properties,and the decrease of residual solvent content causes an obvious increase of tensile strength and tensile modulus of propellant products,indicating its mechanical properties can be partly improved by adjustment of residual solvent content.The outcomes can be used to clarify solvent transport mechanisms and optimize drying process parameters of double-based gun propellants.展开更多
An increasing number of marine aquaculture facilities have been placed in shallow bays and open sea,which might significantly affect hydrodynamic and solute transport processes in marine aquaculture waters.In this stu...An increasing number of marine aquaculture facilities have been placed in shallow bays and open sea,which might significantly affect hydrodynamic and solute transport processes in marine aquaculture waters.In this study,a coupled hydrodynamic and solute transport model was developed with high-resolution schemes in marine aquaculture waters based on depth-averaged shallow water equations.A new expression of drag force was incorporated into the momentum equations to express the resistance of suspended culture cages.The coupled model was used to simulate the effect of suspended structures on tidal currents and the movement of a contaminant cloud in the marine aquaculture of the North Yellow Sea,China.The simulation results showed a low-velocity area appearing inside the aquaculture cage area,with a maximum reduction rate of velocity close to 45%under high-density culture.The results also showed that tidal currents were sensitive to the density of suspended cages,the length of cages,and the drag coefficients of cages.The transport processes of pollutants inside aquaculture facilities were inhibited away from the vicinity of the culture cage area because of the diminished tidal currents.Therefore,the suspended cages significantly affected the transport processes of pollutants in the coastal aquaculture waters.Furthermore,the reduced horizontal velocity significantly decreased the food supply for the aquaculture areas from the surrounding sea.展开更多
In operations research, the transportation problem (TP) is among the earliest and most effective applications of the linear programming problem. Unbalanced transportation problems reflect the reality of supply chain a...In operations research, the transportation problem (TP) is among the earliest and most effective applications of the linear programming problem. Unbalanced transportation problems reflect the reality of supply chain and logistics situations where the available supply of goods may not precisely match the demand at different locations. To deal with an unbalanced transportation problem (UTP), it is essential first to convert it into a balanced transportation problem (BTP) to find an initial basic feasible solution (IBFS) and hence the optimal solution. The present paper is concerned with introducing a new approach to convert an unbalanced transportation problem into a balanced one and as a consequence to obtain optimum total transportation cost. Numerical examples are provided to demonstrate the suggested method.展开更多
Firstly, the macroscopic chemical equilibrium state of a series of chemical reactions between intercrystal brine and its media salt layer (salt deposit) in Qarhan Salt Lake was studied by using the Pitzer theory. Th...Firstly, the macroscopic chemical equilibrium state of a series of chemical reactions between intercrystal brine and its media salt layer (salt deposit) in Qarhan Salt Lake was studied by using the Pitzer theory. The concept of macroscopic solubility product and its relation with accumulated ore dissolving ratio were presented, which are used in the numerical model of dissolving and driving exploitation of potassium salt in Qarhan Salt Lake. And secondly, with a model forming idea of transport model for reacting solutes in the multi-component fresh groundwater system in porous media being a reference, a two-dimensional transport model coupled with a series of chemical reactions in a multi-component brine porous system (salt deposits) was developed by using the Pitzer theory. Meanwhile, the model was applied to model potassium/magnesium transport in Qarhan Salt Lake in order to study the transfer law of solid and liquid phases in the dissolving and driving process and to design the optimal injection/abstraction strategy for dissolving and capturing maximum Potassium/ Magnesium in the mining of salt deposits in Qarhan Salt Lake.展开更多
This paper compares numerical modeling of the effect of stress on solute transport (advection and matrix diffusion) in fractured rocks in which fracture apertures are correlated with fracture lengths. It is mainly m...This paper compares numerical modeling of the effect of stress on solute transport (advection and matrix diffusion) in fractured rocks in which fracture apertures are correlated with fracture lengths. It is mainly motivated by the performance and safety assessments of underground radioactive waste repositories. Five research teams used different approaches to model stress/deformation, flow and transport pro- cesses, based on either discrete fracture network or equivalent continuum models. The simulation results derived by various teams generally demonstrated that rock stresses could significantly influence solute transport processes through stress-induced changes in fracture apertures and associated changes in per- meability. Reasonably good agreement was achieved regarding advection and matrix diffusion given the same fracture network, while some observed discrepancies could be explained by different mechanical or transport modeling approaches.展开更多
Solute carriers(SLCs)are the largest family of transmembrane transporters that determine the exchange of various substances,including nutrients,ions,metabolites,and drugs across biological membranes.To date,the presen...Solute carriers(SLCs)are the largest family of transmembrane transporters that determine the exchange of various substances,including nutrients,ions,metabolites,and drugs across biological membranes.To date,the presence of about 287 SLC genes have been identified in the brain,among which mutations or the resultant dysfunctions of 71 SLC genes have been reported to be correlated with human brain disorders.Although increasing interest in SLCs have focused on drug development,SLCs are currently still under-explored as drug targets,especially in the brain.We summarize the main substrates and functions of SLCs that are expressed in the brain,with an emphasis on selected SLCs that are important physiologically,pathologically,and pharmacologically in the blood-brain barrier,astrocytes,and neurons.Evidence suggests that a fraction of SLCs are regulated along with the occurrences of brain disorders,among which epilepsy,neurodegenerative diseases,and autism are representative.Given the review of SLCs involved in the onset and procession of brain disorders,we hope these SLCs will be screened as promising drug targets to improve drug delivery to the brain.展开更多
Understanding solute transport behaviors of deep soil profile in the Loess Plateau is helpful for ecological construction and agricultural production improvement. In this study, solute transport processes of a deep so...Understanding solute transport behaviors of deep soil profile in the Loess Plateau is helpful for ecological construction and agricultural production improvement. In this study, solute transport processes of a deep soil profile were measured by a conservative tracer experiment using 25 undisturbed soil cores (20 cm long and 7 cm diameter for each) continuously sampled from the surface downward to the depth of 500 cm in the Loess Plateau of China. The solute transport breakthrough curves (BTCs) were analyzed in terms of the convection-dispersion equation (CDE) and the mobile-immobile model (MIM). Average pore-water velocity and dispersion coefficient (or effective dispersion coefficient) were calculated using the CDE and MIM. Basic soil properties and water infiltration parameters were also determined to explore their influence on the solute transport parameters. Both pore-water velocity and dispersion coefficient (or effective dispersion coefficient) generally decreased with increasing depth, and the dispersivity fluctuated along the soil profile. There was a good linear correlation between log-transformed pore-water velocity and dispersion coefficient, with a slope of about 1.0 and an average dispersivity of 0.25 for the entire soil profile. Generally speaking, the soil was more homogeneous along the soil profile. Our results also show that hydrodynamic dispersion is the dominant mechanism of solute transport of loess soils in the study area.展开更多
Levulinic acid(LA)is one of the top-12 most promising biomass-based platform chemicals,which has a wide range of applications in a variety of fields.However,separation and purification of LA from aqueous solution or a...Levulinic acid(LA)is one of the top-12 most promising biomass-based platform chemicals,which has a wide range of applications in a variety of fields.However,separation and purification of LA from aqueous solution or actual hydrolysate continues to be a challenge.Among various downstream separation technologies,liquid-liquid extraction is a low-cost,effective,and simple process to separate LA.The key breakthrough lies in the development of extractants with high extraction efficiency,good hydrophobicity,and low cost.In this work,three hydrophobic deep eutectic solvents(DESs)based on tri-n-octylamine(TOA)as hydrogen bond acceptor(HBA)and alcohols(butanol,2-octanol,and menthol)as hydrogen bond donors(HBDs)were developed to extract LA from aqueous solution.The molar ratios of HBD and HBA,extraction temperature,contact time,solution pH,and initial LA concentration,DES/water volume ratios were systematically investigated.Compared with 2-octanol-TOA and menthol-TOA DES,the butanol-TOA DES exhibited the superior extraction performance for LA,with a maximum extraction efficiency of 95.79±1.4%.Moreover,the solution pH had a great impact on the LA extraction efficiency of butanol-TOA(molar ratio=3:1).It is worth noting that the extraction equilibrium time was less than 0.5 h.More importantly,the butanol-TOA(3:1)DES possesses good extraction abilities for low,medium,and high concentrations of LA.展开更多
In this study, the lattice Boltzmann method (LBM) was used to simulate the solute transport in a single rough fracture. The self-affine rough fracture wall was generated with the successive random addition method. T...In this study, the lattice Boltzmann method (LBM) was used to simulate the solute transport in a single rough fracture. The self-affine rough fracture wall was generated with the successive random addition method. The ability of the developed LBM to simulate the solute transport was validated by Taylor dispersion. The effect of fluid velocity on the solute transport in a single rough fracture was investigated using the LBM. The breakthrough curves (BTCs) for continuous injection sources in rough fractures were analyzed and discussed with different Reynolds numbers (Re). The results show that the rough frac~'e wall leads to a large fluid velocity gradient across the aperture. Consequently, there is a broad distribution of the immobile region along the rough fracture wall. This distribution of the immobile region is very sensitive to the Re and fracture geometry, and the immobile region is enlarged with the increase of Re and roughness. The concentration of the solute front in the mobile region increases with the Re. Furthermore, the Re and roughness have significant effects on BTCs, and the slow solute molecule exchange between the mobile and immobile regions results in a long breakthrough tail for the rough fracture. This study also demonstrates that the developed LBM can be effective in studying the solute transport in a rough fracture.展开更多
The impact of normal stress-induced closure on fluid flow and solute transport in a single rock fracture is demonstrated in this study.The fracture is created from a measured surface of a granite rock sample.The Bandi...The impact of normal stress-induced closure on fluid flow and solute transport in a single rock fracture is demonstrated in this study.The fracture is created from a measured surface of a granite rock sample.The Bandis model is used to calculate the fracture closure due to normal stress,and the fluid flow is simulated by solving the Reynold equation.The Lagrangian particle tracking method is applied to modeling the advective transport in the fracture.The results show that the normal stress significantly affects fluid flow and solute transport in rock fractures.It causes fracture closure and creates asperity contact areas,which significantly reduces the effective hydraulic aperture and enhances flow channeling.Consequently,the reduced aperture and enhanced channeling affect travel time distributions.In particular,the enhanced channeling results in enhanced first arriving and tailing behaviors for solute transport.The fracture normal stiffness correlates linearly with the 5th and 95th percentiles of the normalized travel time.The finding from this study may help to better understand the stress-dependent solute transport processes in natural rock fractures.展开更多
The hydrodynamic dispersion is an important factor influencing the reactive solute transport in the porous media, and many previous studies assumed that it linearly varied with the average velocity of the groundwater ...The hydrodynamic dispersion is an important factor influencing the reactive solute transport in the porous media, and many previous studies assumed that it linearly varied with the average velocity of the groundwater flow. Actually, such linear relationship has been challenged by more and more experimental observations, even in homogeneous media. In this study, we aim to investigate the relationship between hydrodynamics dispersion and the flow velocity in different types of porous media through a laboratory-controlled experiment. The results indicate that (1) the dispersion coefficient should not be a linear function of the flow velocity when the relationship between the flow velocity and the hydraulic gradient can be described by Darcy's law satisfactorily;(2) Power function works well in describing the dispersion coefficient changing with the flow velocity for different types of porous media, and the power value is between 1.0-2.0 for different particle sizes.展开更多
A modified multi-component solute diffusion equation described with diffusion flux was derived in detail based on the classical MaxwellStefan diffusion theory. The friction between the solute species and the soil skel...A modified multi-component solute diffusion equation described with diffusion flux was derived in detail based on the classical MaxwellStefan diffusion theory. The friction between the solute species and the soil skeleton wall, which is proportional to the relative velocity between the solute species and the soil skeleton, is introduced. The chemical potential gradient is considered the driving force. A one-dimensional model for transport of multi-component solute in saturated soil was developed based on the modified diffusion equation and the modified competitive Langmuir adsorption equation. Numerical calculation of a case of two heavy metal ion species, which was chosen as an example, was carried out using the finite element software COMSOL Multiphysics. A comparative analysis was performed between the multi-component solute transport model developed in this study and the convection-diffusion transport model of single-component solute based on Fick's law. Simulation results show that the transport behavior of each species in a multi-component solute system is different from that in a single-component system, and the friction characteristics considered in the developed model contribute to obstructing the movement of each solute component. At the same time,the influence of modified competitive Langmuir adsorption on solute transport was investigated. These research results can provide strong theoretical support for the design of antifouling barriers in landfills and the maintenance of operation stability.展开更多
Room temperature sputtered inorganic nickel oxide(NiO_(x))is one of the most promising hole transport layers(HTL)for perovskite-sillion 2-terminal tandem solar cells with the aid of ultrathin and compact organic layer...Room temperature sputtered inorganic nickel oxide(NiO_(x))is one of the most promising hole transport layers(HTL)for perovskite-sillion 2-terminal tandem solar cells with the aid of ultrathin and compact organic layers to passivate the surface defects.In this study,the aromatic solvent with different substituent groups was used to regulate the conformation of poly[bis(4-phenyl)(2,4,6-trimethylphenyl)am ine](PTAA)layer.As a result,the single-junction perovskite solar cell(PSC)gained a power conversion efficiency(PCE)of 20.63%,contributing to a 27.21%efficiency for monolithic perovskite/silicon(double-side polished)2-terminal tandem solar cell,by applying the alkyl aromatic solvent to enhance theπ-πstacking of PTAA molecular chains.The tandem solar cell can maintain 95%initial efficiency after aging over 1000 h.This study provides a universal approach for improving the photovoltaic performance of NiO_(x)/polymer-based perovskite/silicon tandem solar cells and other single junction inverted PSCs.展开更多
This paper dealt with the development of a two-dimensional (2D) mathematical model for column leaching and confirmed the important simulation parameters through experiment. The unsaturated state of the variably satu...This paper dealt with the development of a two-dimensional (2D) mathematical model for column leaching and confirmed the important simulation parameters through experiment. The unsaturated state of the variably saturated flow column and the solute transport of copper ions were studied during leaching. The fluid flow problem was handled using the Richards equation on the premise of an ambient pressure column air, where the van Genuchten formulas were applied to define the nonlinear relationships of pressure head with the retention and permeability properties. The ore column permeability test gave a varied hydraulic conductivity, which was analyzed in the model. In the solute transport problem, the copper ion concentration was solved using the advection-diffusion-reaction equation whose reaction term was determined by the joint analysis of experimental copper leaching rate and the shrinking core model. Particle-and column-scale leaching tests were carried out to illustrate the difference and connection of copper extraction in both processes. This fluid flow and solute transport cou-pled model was determined through the finite element method using the numerical simulation software, COMSOL Multiphysics.展开更多
Minimizing transportation time and getting optimal solutions are always considered as important factors while solving transportation problem. This paper shows a new approach for finding initial basic solution for tran...Minimizing transportation time and getting optimal solutions are always considered as important factors while solving transportation problem. This paper shows a new approach for finding initial basic solution for transportation problem which reduces cost of transportation more than any transportation method such as LCM, northwest, Vogel’s approximation and so on. This method has been illustrated by taking an example;afterwards, it compares basic initial feasible solution with other methods IBF and optimal dictate solutions such as MODI and Steppingstone method.展开更多
The diffusion coefficients(Dapp) and the heterogeneous electron transfer rate constants(ks)for ferrocene in several polymer solvents were determined by using steady-stae voltammetry. Thetemperature dependence of the t...The diffusion coefficients(Dapp) and the heterogeneous electron transfer rate constants(ks)for ferrocene in several polymer solvents were determined by using steady-stae voltammetry. Thetemperature dependence of the two parameters indicates Arrhenius behavior. The polymer solventeffects on diffusion and electron transfer dynamics of ferrocene were discussed展开更多
The groundwater tracer injection and withdrawal tests are often carried out for the determination of aquifer solute transport parameters.However,the parameter analyses encounter a great difficulty due to the radial fl...The groundwater tracer injection and withdrawal tests are often carried out for the determination of aquifer solute transport parameters.However,the parameter analyses encounter a great difficulty due to the radial flow nature and the variability of the temporal boundary conditions.An adaptive methodology for the determination of groundwater solute transport parameters using tracer injection and withdrawal test data had been developed and illustrated through an actual case.The methodology includes the treatment of the tracer boundary condition at the tracer injection well,the normalization of tracer concentration,the groundwater solute transport finite element modelling and the method of least squares to optimize the parameters.An application of this methodology was carried out in a field test in the South of Hanoi city.The tested aquifer is Pleistocene aquifer,which is a main aquifer and has been providing domestic water supply to the city since the French time.Effective porosity of 0.31,longitudinal dispersivity of 2.2 m,and hydrodynamic dispersion coefficients from D=220 m^(2)/d right outside the pumping well screen to D=15.8 m^(2)/d right outside the tracer injection well screen have been obtained for the aquifer at the test site.The minimal sum of squares of the differences between the observed and model normalized tracer concentration is 0.00119,which is corresponding to the average absolute difference between observed and model normalized concentrations of 0.0355(while 1 is the worst and 0 is the best fit).展开更多
Based on the momentum and mass conservation equations,a comprehensive model of heap bioleaching process is developed to investigate the interaction between chemical reactions,solution flow,gas flow,and solute transpor...Based on the momentum and mass conservation equations,a comprehensive model of heap bioleaching process is developed to investigate the interaction between chemical reactions,solution flow,gas flow,and solute transport within the leaching system.The governing equations are solved numerically using the COMSOL Multiphysics software for the coupled reactive flow and solute transport at micro-scale,meso-scale and macro-scale levels.At or near the surface of ore particle,the acid concentration is relatively higher than that in the central area,while the concentration gradient decreases after 72 d of leaching.The flow simulation between ore particles by combining X-ray CT technology shows that the highest velocity in narrow pore reaches 0.375 m/s.The air velocity within the dump shows that the velocity near the top and side surface is relatively high,which leads to the high oxygen concentration in that area.The coupled heat transfer and liquid flow process shows that the solution can act as an effective remover from the heap,dropping the highest temperature from 60 to 38 °C.The reagent transfer coupled with solution flow is also analyzed.The results obtained allow us to obtain a better understanding of the fundamental physical phenomenon of the bioleaching process.展开更多
The transport of fluid, nutrients, and signaling molecules in the bone lacunar-canalicular system (LCS) is critical for osteocyte survival and function. We have applied the fluorescence recovery after photobleaching...The transport of fluid, nutrients, and signaling molecules in the bone lacunar-canalicular system (LCS) is critical for osteocyte survival and function. We have applied the fluorescence recovery after photobleaching (FRAP) approach to quantify load-induced fluid and solute transport in the LCS in situ, but the measurements were limited to cortical regions 30-50 μm underneath the periosteum due to the constrains of laser penetration. With this work, we aimed to expand our understanding of load-induced fluid and solute transport in both trabecular and cortical bone using a multiscaled image-based finite element analysis (FEA) approach. An intact murine tibia was first re-constructed from microCT images into a three-dimensional (3D) linear elastic FEA model, and the matrix deformations at various locations were calculated under axial loading. A segment of the above 3D model was then imported to the biphasic poroelasticity analysis platform (FEBio) to predict load-induced fluid pressure fields, and interstitial solute/fluid flows through LCS in both cortical and trabecular regions. Further, secondary flow effects such as the shear stress and/or drag force acting on osteocytes, the presumed mechano-sensors in bone, were derived using the previously developed ultrastructural model of Brinkman flow in the canaliculi. The material properties assumed in the FEA models were validated against previously obtained strain and FRAP transport data measured on the cortical cortex. Our results demonstrated the feasibility of this computational approach in estimating the fluid flux in the LCS and the cellular stimulation forces (shear and drag forces) for osteocytes in any cortical and trabecular bone locations, allowing further studies of how the activation of osteocytes correlates with in vivo functional bone formation. The study provides a promising platform to reveal potential cellular mechanisms underlying the anabolic power of exercises and physical activities in treating patients with skeletal deficiencies.展开更多
文摘The wadi dahab delta is in a dry, arid coastal zone within Egypt’s south Sinai Peninsula’s eastern portion. The primary water source is the Quaternary coastal alluvial aquifer. The groundwater salinity varies from 890to 8213 mg/L, with a mean value of 3417 mg/L. The dissolved major ions have been used to calculate the seawater mixing index(SWMI) using a linear equation that discriminates the groundwater mostly affected by water–rock interaction(SWMI 1>) and other samples mixed with Seawater(SWMI < 1). The isotopic composition of groundwater for specifically chosen groundwater samples ranges from-0.645‰ to +5.212‰ for δ^(18)O and from-9.582‰ to + 22.778‰ for δ^(2)H, where the seawater represented by a Red Sea water sample(δ^(18)O + 1.64‰-δ^(2)H + 9.80‰) and reject brine water are considerably enriched the isotopic groundwater values. The geochemical NETPATH model constrained by the dissolved significant ions, isotopes, and the rock aquifer forming minerals as phases indicate the mixing percent with the seawater ranges from 9% to 97% of seawater from 91% to 3% of original recharge water. According to the SEAWAT 3-D flow models, seawater has penetrated the Northeastern Dahab delta aquifer, with the intrusion zone extending1500 m inland. The salt dissolution, upwelling of saline water, recharge from the upstream mountain block, and seawater encroachment are the primary aspects contributing to the deterioration of groundwater quality. These findings may have significance for effective groundwater withdrawal management in arid locations worldwide with similar hydrogeological systems.
基金the National Natural Science Foundation of China(Grant No.22075146).
文摘Appropriate drying process with optimized controlling of drying parameters plays a vital role in the improvement of the quality and performance of propellant products.However,few research on solvent transport dynamics within NC-based propellants was reported,and its effect on the evolution of mechanical properties was not interpreted yet.This study is conducted to gain a comprehensive understanding of hot-air drying for NC-based propellants and clarify the effect of temperature on solvent transport behavior and further the change of mechanical properties during drying.The drying kinetic curves show the drying time required is decreased but the steady solvent content is increased and the drying rate is obviously increased with the increase of hot-air temperatures,indicating hot-air temperatures have a significant effect on drying kinetics.A modified drying model was established,and results show it is more appropriate to describe solvent transport behavior within NC-based propellants.Moreover,two linear equations were established to exhibit the relationship between solvent content and its effect on the change of tensile properties,and the decrease of residual solvent content causes an obvious increase of tensile strength and tensile modulus of propellant products,indicating its mechanical properties can be partly improved by adjustment of residual solvent content.The outcomes can be used to clarify solvent transport mechanisms and optimize drying process parameters of double-based gun propellants.
基金supported by the National Nature Science Foundation of China(Grants No.51879028 and U21A20155)the National Key Research and Development Program of China(Grant No.2019YFC1407704)+1 种基金the Open Fund of the State Key Laboratory of Coastal and Offshore Engineering,Dalian University of Technology(Grant No.LP2009)the Dalian Science and Technology Innovation Fund Project(Grant No.2021JJ11CG001)。
文摘An increasing number of marine aquaculture facilities have been placed in shallow bays and open sea,which might significantly affect hydrodynamic and solute transport processes in marine aquaculture waters.In this study,a coupled hydrodynamic and solute transport model was developed with high-resolution schemes in marine aquaculture waters based on depth-averaged shallow water equations.A new expression of drag force was incorporated into the momentum equations to express the resistance of suspended culture cages.The coupled model was used to simulate the effect of suspended structures on tidal currents and the movement of a contaminant cloud in the marine aquaculture of the North Yellow Sea,China.The simulation results showed a low-velocity area appearing inside the aquaculture cage area,with a maximum reduction rate of velocity close to 45%under high-density culture.The results also showed that tidal currents were sensitive to the density of suspended cages,the length of cages,and the drag coefficients of cages.The transport processes of pollutants inside aquaculture facilities were inhibited away from the vicinity of the culture cage area because of the diminished tidal currents.Therefore,the suspended cages significantly affected the transport processes of pollutants in the coastal aquaculture waters.Furthermore,the reduced horizontal velocity significantly decreased the food supply for the aquaculture areas from the surrounding sea.
文摘In operations research, the transportation problem (TP) is among the earliest and most effective applications of the linear programming problem. Unbalanced transportation problems reflect the reality of supply chain and logistics situations where the available supply of goods may not precisely match the demand at different locations. To deal with an unbalanced transportation problem (UTP), it is essential first to convert it into a balanced transportation problem (BTP) to find an initial basic feasible solution (IBFS) and hence the optimal solution. The present paper is concerned with introducing a new approach to convert an unbalanced transportation problem into a balanced one and as a consequence to obtain optimum total transportation cost. Numerical examples are provided to demonstrate the suggested method.
基金the National Natural Science Foundation of China
文摘Firstly, the macroscopic chemical equilibrium state of a series of chemical reactions between intercrystal brine and its media salt layer (salt deposit) in Qarhan Salt Lake was studied by using the Pitzer theory. The concept of macroscopic solubility product and its relation with accumulated ore dissolving ratio were presented, which are used in the numerical model of dissolving and driving exploitation of potassium salt in Qarhan Salt Lake. And secondly, with a model forming idea of transport model for reacting solutes in the multi-component fresh groundwater system in porous media being a reference, a two-dimensional transport model coupled with a series of chemical reactions in a multi-component brine porous system (salt deposits) was developed by using the Pitzer theory. Meanwhile, the model was applied to model potassium/magnesium transport in Qarhan Salt Lake in order to study the transfer law of solid and liquid phases in the dissolving and driving process and to design the optimal injection/abstraction strategy for dissolving and capturing maximum Potassium/ Magnesium in the mining of salt deposits in Qarhan Salt Lake.
基金the context of the international DECOVALEX-2011 ProjectLBNL from NDA via SERCO TAS was provided through the U.S. Department of Energy Contract No. DE-AC02-05CH11231supported by the Ministry of Education of the Czech Republic within the SGS project No. 7822/115 on the TUL
文摘This paper compares numerical modeling of the effect of stress on solute transport (advection and matrix diffusion) in fractured rocks in which fracture apertures are correlated with fracture lengths. It is mainly motivated by the performance and safety assessments of underground radioactive waste repositories. Five research teams used different approaches to model stress/deformation, flow and transport pro- cesses, based on either discrete fracture network or equivalent continuum models. The simulation results derived by various teams generally demonstrated that rock stresses could significantly influence solute transport processes through stress-induced changes in fracture apertures and associated changes in per- meability. Reasonably good agreement was achieved regarding advection and matrix diffusion given the same fracture network, while some observed discrepancies could be explained by different mechanical or transport modeling approaches.
基金This work was supported by Nation Science and Technology Major Projects for Major New Drugs Innovation and Development(2018ZX09711003-004-002 to L.C.)Ministry of Science and Technology of China National Key R&D Programs(2018YFA0506903 to L.C.)National Natural Science Foundation of China grants(91857108 to L.C.).
文摘Solute carriers(SLCs)are the largest family of transmembrane transporters that determine the exchange of various substances,including nutrients,ions,metabolites,and drugs across biological membranes.To date,the presence of about 287 SLC genes have been identified in the brain,among which mutations or the resultant dysfunctions of 71 SLC genes have been reported to be correlated with human brain disorders.Although increasing interest in SLCs have focused on drug development,SLCs are currently still under-explored as drug targets,especially in the brain.We summarize the main substrates and functions of SLCs that are expressed in the brain,with an emphasis on selected SLCs that are important physiologically,pathologically,and pharmacologically in the blood-brain barrier,astrocytes,and neurons.Evidence suggests that a fraction of SLCs are regulated along with the occurrences of brain disorders,among which epilepsy,neurodegenerative diseases,and autism are representative.Given the review of SLCs involved in the onset and procession of brain disorders,we hope these SLCs will be screened as promising drug targets to improve drug delivery to the brain.
基金supported by the National Natural Science Foundation of China(41571130081,41530854)
文摘Understanding solute transport behaviors of deep soil profile in the Loess Plateau is helpful for ecological construction and agricultural production improvement. In this study, solute transport processes of a deep soil profile were measured by a conservative tracer experiment using 25 undisturbed soil cores (20 cm long and 7 cm diameter for each) continuously sampled from the surface downward to the depth of 500 cm in the Loess Plateau of China. The solute transport breakthrough curves (BTCs) were analyzed in terms of the convection-dispersion equation (CDE) and the mobile-immobile model (MIM). Average pore-water velocity and dispersion coefficient (or effective dispersion coefficient) were calculated using the CDE and MIM. Basic soil properties and water infiltration parameters were also determined to explore their influence on the solute transport parameters. Both pore-water velocity and dispersion coefficient (or effective dispersion coefficient) generally decreased with increasing depth, and the dispersivity fluctuated along the soil profile. There was a good linear correlation between log-transformed pore-water velocity and dispersion coefficient, with a slope of about 1.0 and an average dispersivity of 0.25 for the entire soil profile. Generally speaking, the soil was more homogeneous along the soil profile. Our results also show that hydrodynamic dispersion is the dominant mechanism of solute transport of loess soils in the study area.
基金supported by the Key Area Research&Development Program of Guangdong Province(2020B0101070001)the National Natural Science Foundation of China(21978053,51508547)。
文摘Levulinic acid(LA)is one of the top-12 most promising biomass-based platform chemicals,which has a wide range of applications in a variety of fields.However,separation and purification of LA from aqueous solution or actual hydrolysate continues to be a challenge.Among various downstream separation technologies,liquid-liquid extraction is a low-cost,effective,and simple process to separate LA.The key breakthrough lies in the development of extractants with high extraction efficiency,good hydrophobicity,and low cost.In this work,three hydrophobic deep eutectic solvents(DESs)based on tri-n-octylamine(TOA)as hydrogen bond acceptor(HBA)and alcohols(butanol,2-octanol,and menthol)as hydrogen bond donors(HBDs)were developed to extract LA from aqueous solution.The molar ratios of HBD and HBA,extraction temperature,contact time,solution pH,and initial LA concentration,DES/water volume ratios were systematically investigated.Compared with 2-octanol-TOA and menthol-TOA DES,the butanol-TOA DES exhibited the superior extraction performance for LA,with a maximum extraction efficiency of 95.79±1.4%.Moreover,the solution pH had a great impact on the LA extraction efficiency of butanol-TOA(molar ratio=3:1).It is worth noting that the extraction equilibrium time was less than 0.5 h.More importantly,the butanol-TOA(3:1)DES possesses good extraction abilities for low,medium,and high concentrations of LA.
基金supported by the National Natural Science Foundation of China(Grants No.51079043,41172204,and 51109139)the Natural Science Foundation of Jiangsu Province(Grant No.BK2011110)
文摘In this study, the lattice Boltzmann method (LBM) was used to simulate the solute transport in a single rough fracture. The self-affine rough fracture wall was generated with the successive random addition method. The ability of the developed LBM to simulate the solute transport was validated by Taylor dispersion. The effect of fluid velocity on the solute transport in a single rough fracture was investigated using the LBM. The breakthrough curves (BTCs) for continuous injection sources in rough fractures were analyzed and discussed with different Reynolds numbers (Re). The results show that the rough frac~'e wall leads to a large fluid velocity gradient across the aperture. Consequently, there is a broad distribution of the immobile region along the rough fracture wall. This distribution of the immobile region is very sensitive to the Re and fracture geometry, and the immobile region is enlarged with the increase of Re and roughness. The concentration of the solute front in the mobile region increases with the Re. Furthermore, the Re and roughness have significant effects on BTCs, and the slow solute molecule exchange between the mobile and immobile regions results in a long breakthrough tail for the rough fracture. This study also demonstrates that the developed LBM can be effective in studying the solute transport in a rough fracture.
基金funding provided by the Swedish Nuclear Fuel and Waste Management Co.(SKB)。
文摘The impact of normal stress-induced closure on fluid flow and solute transport in a single rock fracture is demonstrated in this study.The fracture is created from a measured surface of a granite rock sample.The Bandis model is used to calculate the fracture closure due to normal stress,and the fluid flow is simulated by solving the Reynold equation.The Lagrangian particle tracking method is applied to modeling the advective transport in the fracture.The results show that the normal stress significantly affects fluid flow and solute transport in rock fractures.It causes fracture closure and creates asperity contact areas,which significantly reduces the effective hydraulic aperture and enhances flow channeling.Consequently,the reduced aperture and enhanced channeling affect travel time distributions.In particular,the enhanced channeling results in enhanced first arriving and tailing behaviors for solute transport.The fracture normal stiffness correlates linearly with the 5th and 95th percentiles of the normalized travel time.The finding from this study may help to better understand the stress-dependent solute transport processes in natural rock fractures.
基金partially supported by the National Natural Science Foundation of China (Grant Nos. 41831289, 41877191, 41602256)
文摘The hydrodynamic dispersion is an important factor influencing the reactive solute transport in the porous media, and many previous studies assumed that it linearly varied with the average velocity of the groundwater flow. Actually, such linear relationship has been challenged by more and more experimental observations, even in homogeneous media. In this study, we aim to investigate the relationship between hydrodynamics dispersion and the flow velocity in different types of porous media through a laboratory-controlled experiment. The results indicate that (1) the dispersion coefficient should not be a linear function of the flow velocity when the relationship between the flow velocity and the hydraulic gradient can be described by Darcy's law satisfactorily;(2) Power function works well in describing the dispersion coefficient changing with the flow velocity for different types of porous media, and the power value is between 1.0-2.0 for different particle sizes.
基金supported by the National Basic Research Program of China(Grant No.2014CB744702)the Beijing Natural Science Foundation Key Projects(Grant No.8171001)the National Natural Science Foundation of China(Grant No.51678012)
文摘A modified multi-component solute diffusion equation described with diffusion flux was derived in detail based on the classical MaxwellStefan diffusion theory. The friction between the solute species and the soil skeleton wall, which is proportional to the relative velocity between the solute species and the soil skeleton, is introduced. The chemical potential gradient is considered the driving force. A one-dimensional model for transport of multi-component solute in saturated soil was developed based on the modified diffusion equation and the modified competitive Langmuir adsorption equation. Numerical calculation of a case of two heavy metal ion species, which was chosen as an example, was carried out using the finite element software COMSOL Multiphysics. A comparative analysis was performed between the multi-component solute transport model developed in this study and the convection-diffusion transport model of single-component solute based on Fick's law. Simulation results show that the transport behavior of each species in a multi-component solute system is different from that in a single-component system, and the friction characteristics considered in the developed model contribute to obstructing the movement of each solute component. At the same time,the influence of modified competitive Langmuir adsorption on solute transport was investigated. These research results can provide strong theoretical support for the design of antifouling barriers in landfills and the maintenance of operation stability.
基金supported by the National Key R&D Program of China(2018YFB1500103)the National Natural Science Foundation of China(62104082)+1 种基金the Guangdong Basic and Applied Basic Research Foundation(2022A1515010746,2022A1515011228)the Science and Technology Program of Guangzhou(202201010458)。
文摘Room temperature sputtered inorganic nickel oxide(NiO_(x))is one of the most promising hole transport layers(HTL)for perovskite-sillion 2-terminal tandem solar cells with the aid of ultrathin and compact organic layers to passivate the surface defects.In this study,the aromatic solvent with different substituent groups was used to regulate the conformation of poly[bis(4-phenyl)(2,4,6-trimethylphenyl)am ine](PTAA)layer.As a result,the single-junction perovskite solar cell(PSC)gained a power conversion efficiency(PCE)of 20.63%,contributing to a 27.21%efficiency for monolithic perovskite/silicon(double-side polished)2-terminal tandem solar cell,by applying the alkyl aromatic solvent to enhance theπ-πstacking of PTAA molecular chains.The tandem solar cell can maintain 95%initial efficiency after aging over 1000 h.This study provides a universal approach for improving the photovoltaic performance of NiO_(x)/polymer-based perovskite/silicon tandem solar cells and other single junction inverted PSCs.
基金financially supported by the NationalNatural Science Foundation of China(Nos.50934002,51104100,and 51074013)the National Key Technologies R&D Program of China(No.2012BAB08B02)
文摘This paper dealt with the development of a two-dimensional (2D) mathematical model for column leaching and confirmed the important simulation parameters through experiment. The unsaturated state of the variably saturated flow column and the solute transport of copper ions were studied during leaching. The fluid flow problem was handled using the Richards equation on the premise of an ambient pressure column air, where the van Genuchten formulas were applied to define the nonlinear relationships of pressure head with the retention and permeability properties. The ore column permeability test gave a varied hydraulic conductivity, which was analyzed in the model. In the solute transport problem, the copper ion concentration was solved using the advection-diffusion-reaction equation whose reaction term was determined by the joint analysis of experimental copper leaching rate and the shrinking core model. Particle-and column-scale leaching tests were carried out to illustrate the difference and connection of copper extraction in both processes. This fluid flow and solute transport cou-pled model was determined through the finite element method using the numerical simulation software, COMSOL Multiphysics.
文摘Minimizing transportation time and getting optimal solutions are always considered as important factors while solving transportation problem. This paper shows a new approach for finding initial basic solution for transportation problem which reduces cost of transportation more than any transportation method such as LCM, northwest, Vogel’s approximation and so on. This method has been illustrated by taking an example;afterwards, it compares basic initial feasible solution with other methods IBF and optimal dictate solutions such as MODI and Steppingstone method.
文摘The diffusion coefficients(Dapp) and the heterogeneous electron transfer rate constants(ks)for ferrocene in several polymer solvents were determined by using steady-stae voltammetry. Thetemperature dependence of the two parameters indicates Arrhenius behavior. The polymer solventeffects on diffusion and electron transfer dynamics of ferrocene were discussed
文摘The groundwater tracer injection and withdrawal tests are often carried out for the determination of aquifer solute transport parameters.However,the parameter analyses encounter a great difficulty due to the radial flow nature and the variability of the temporal boundary conditions.An adaptive methodology for the determination of groundwater solute transport parameters using tracer injection and withdrawal test data had been developed and illustrated through an actual case.The methodology includes the treatment of the tracer boundary condition at the tracer injection well,the normalization of tracer concentration,the groundwater solute transport finite element modelling and the method of least squares to optimize the parameters.An application of this methodology was carried out in a field test in the South of Hanoi city.The tested aquifer is Pleistocene aquifer,which is a main aquifer and has been providing domestic water supply to the city since the French time.Effective porosity of 0.31,longitudinal dispersivity of 2.2 m,and hydrodynamic dispersion coefficients from D=220 m^(2)/d right outside the pumping well screen to D=15.8 m^(2)/d right outside the tracer injection well screen have been obtained for the aquifer at the test site.The minimal sum of squares of the differences between the observed and model normalized tracer concentration is 0.00119,which is corresponding to the average absolute difference between observed and model normalized concentrations of 0.0355(while 1 is the worst and 0 is the best fit).
基金Projects(50934002,51104011) supported by the National Natural Science Foundation of ChinaProject(IRT0950) supported by Program for Changjiang Scholars and Innovative Research Team in Chinese UniversityProject(20100480200) supported by China Postdoctoral Science Foundation
文摘Based on the momentum and mass conservation equations,a comprehensive model of heap bioleaching process is developed to investigate the interaction between chemical reactions,solution flow,gas flow,and solute transport within the leaching system.The governing equations are solved numerically using the COMSOL Multiphysics software for the coupled reactive flow and solute transport at micro-scale,meso-scale and macro-scale levels.At or near the surface of ore particle,the acid concentration is relatively higher than that in the central area,while the concentration gradient decreases after 72 d of leaching.The flow simulation between ore particles by combining X-ray CT technology shows that the highest velocity in narrow pore reaches 0.375 m/s.The air velocity within the dump shows that the velocity near the top and side surface is relatively high,which leads to the high oxygen concentration in that area.The coupled heat transfer and liquid flow process shows that the solution can act as an effective remover from the heap,dropping the highest temperature from 60 to 38 °C.The reagent transfer coupled with solution flow is also analyzed.The results obtained allow us to obtain a better understanding of the fundamental physical phenomenon of the bioleaching process.
基金supported by grants from NIH (P30GM103333 and RO1AR054385 to LW)China CSC fellowship (to LF)DOD W81XWH-13-1-0148 (to XLL)
文摘The transport of fluid, nutrients, and signaling molecules in the bone lacunar-canalicular system (LCS) is critical for osteocyte survival and function. We have applied the fluorescence recovery after photobleaching (FRAP) approach to quantify load-induced fluid and solute transport in the LCS in situ, but the measurements were limited to cortical regions 30-50 μm underneath the periosteum due to the constrains of laser penetration. With this work, we aimed to expand our understanding of load-induced fluid and solute transport in both trabecular and cortical bone using a multiscaled image-based finite element analysis (FEA) approach. An intact murine tibia was first re-constructed from microCT images into a three-dimensional (3D) linear elastic FEA model, and the matrix deformations at various locations were calculated under axial loading. A segment of the above 3D model was then imported to the biphasic poroelasticity analysis platform (FEBio) to predict load-induced fluid pressure fields, and interstitial solute/fluid flows through LCS in both cortical and trabecular regions. Further, secondary flow effects such as the shear stress and/or drag force acting on osteocytes, the presumed mechano-sensors in bone, were derived using the previously developed ultrastructural model of Brinkman flow in the canaliculi. The material properties assumed in the FEA models were validated against previously obtained strain and FRAP transport data measured on the cortical cortex. Our results demonstrated the feasibility of this computational approach in estimating the fluid flux in the LCS and the cellular stimulation forces (shear and drag forces) for osteocytes in any cortical and trabecular bone locations, allowing further studies of how the activation of osteocytes correlates with in vivo functional bone formation. The study provides a promising platform to reveal potential cellular mechanisms underlying the anabolic power of exercises and physical activities in treating patients with skeletal deficiencies.