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Extracellular synthesis of silver nanoparticles by Pseudomonas sp. THG-LS1.4 and their antimicrobial application 被引量:1
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作者 Hina Singh Juan Du +1 位作者 Priyanka Singh Tae Hoo Yi 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2018年第4期258-264,共7页
Silver nanoparticles(Ag NPs) are known to have bacteriostatic and bactericidal effects. The present study highlights the extracellular synthesis of Ag NPs and its antibacterial properties. The Ag NPs were synthesize... Silver nanoparticles(Ag NPs) are known to have bacteriostatic and bactericidal effects. The present study highlights the extracellular synthesis of Ag NPs and its antibacterial properties. The Ag NPs were synthesized using Pseudomonas sp. THG-LS1.4 strain which had been isolated from soil. The Ag NPs were characterized by field emission-transmission electron microscopy(FE-TEM), X-ray diffraction(XRD),Fourier transform-infrared(FT-IR) spectroscopy, and particle size distribution(DLS). The Ag NPs displayed maximum absorbance at 412 nm and were irregular in shape ranging from 10 to 40 nm. The XRD spectroscopy results demonstrated the crystalline nature of nanoparticles. The Ag NPs showed antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Candida tropicalis, Vibrio parahaemolyticus, Escherichia coli and Pseudomonas aeruginosa. Furthermore, the Ag NPs were also evaluated for their increased antibacterial activities with various antibiotics against Escherichia coli, Pseudomonas aeruginosa and Salmonella enterica. Additionally, Ag NPs showd biofilm inhibition activity. The biosynthesized Ag NPs were found to be a potent agent against tested pathogens. More importantly, we highlight the applications of Ag NPs as an antimicrobial agent. 展开更多
关键词 Extracellular synthesis Silver nanoparticles Pseudomonas sp.thg-ls1.4 Antimicrobial activity
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