目的报道1例在鞍区精原细胞瘤放化疗后出现C型尼曼-匹克病(Niemann-Pick disease type C,NPC)的病例,加强对尼曼-匹克病(Niemann-Pick disease,NPD)的了解。方法对南部战区总医院内分泌科2021年6月收治的1例鞍区精原细胞瘤切除术、放化...目的报道1例在鞍区精原细胞瘤放化疗后出现C型尼曼-匹克病(Niemann-Pick disease type C,NPC)的病例,加强对尼曼-匹克病(Niemann-Pick disease,NPD)的了解。方法对南部战区总医院内分泌科2021年6月收治的1例鞍区精原细胞瘤切除术、放化疗后逐渐出现垂体功能减退、重度肝损害、肝脾大,激素替代治疗后引起继发性糖尿病的青少年患者长达4年的病史进行回顾性分析。结果本例患者为青少年女性,鞍区精原细胞瘤切除术及放化疗后,逐渐出现不同程度血细胞下降、脂代谢异常、肝功能异常、肝脾增大等,行骨髓穿刺,形态学发现2%尼曼-匹克细胞,最终诊断为NPC。经输血、护肝、胰岛素降糖、激素替代等对症治疗后,各项指标较治疗前好转,精神较入院时稍好转,但患者仍存在黄疸、肝脾大,偶有精神异常。目前继续门诊随访,予对症治疗。结论对于颅内肿瘤术后或放化疗后所致内分泌与代谢相关症状,且同时伴有难以解释的神经、精神、脏器功能异常时,要考虑到NPC的可能性,可通过骨髓穿刺涂片发现尼曼-匹克细胞初步诊断。目前NPC的治疗以对症为主。展开更多
In this paper, we give existence theorems of common fixed points for two mappings with a weakly C*-contractive condition on partially ordered 2-metric spaces and give a sufficient condition under which there exists a ...In this paper, we give existence theorems of common fixed points for two mappings with a weakly C*-contractive condition on partially ordered 2-metric spaces and give a sufficient condition under which there exists a unique common fixed point.展开更多
The degree of approximation to a function f(x)∈C[-1,1] by (U, λ) means and f(x) ∈ Lpw by (Jr) means are discussed, some results in the literatures [1],[2],[3] have been improved.
Kunio Hidano[4] has shown that the global and local C2-solutions for semilinear wave equations with spherical symmetry in three space dimensions. This paper studies the global and local C2-solutions for the semilinea...Kunio Hidano[4] has shown that the global and local C2-solutions for semilinear wave equations with spherical symmetry in three space dimensions. This paper studies the global and local C2-solutions for the semilinear wave equations without spherical symmetry in three space dimensions. A problem put forward by Hiroyuki Takamura[2] is partially answered.展开更多
In this article, we introduce and investigate the concept of multivalued hybrid mappings in C AT（0） spaces by using the concept of quasilinearization. Also, we present a new iterative algorithm involving products of...In this article, we introduce and investigate the concept of multivalued hybrid mappings in C AT（0） spaces by using the concept of quasilinearization. Also, we present a new iterative algorithm involving products of Moreau-Yosida resolvents for finding a common element of the set of minimizers of a finite family of convex functions and a common fixed point of two multivalued hybrid mappings in C AT（0） spaces.展开更多
In this study, we simulated space flight of the nematode, Caenorhabditis elegans, on the ground and examined how it is affected by space radiation and G-forces. We simulated G-forces during launch in a gravity acceler...In this study, we simulated space flight of the nematode, Caenorhabditis elegans, on the ground and examined how it is affected by space radiation and G-forces. We simulated G-forces during launch in a gravity acceleration laboratory device in order to identify and isolate the effects of the G-forces. Following this, we irradiated C. elegans with accelerated protons (MC-50 Cyclotron) and gamma rays (iR 222 machine) at the same physical dose. We calculated the expected radiation dose according to Reitz [1] and simulation programs (NASA AP8MIN [2], NASA AE8MAX [2], and CREAM86 [3]) for 1 month (dose rate: 6 × 10-3 Gy;2.8 × 10-2 Gy), 6 months (dose rate: 36 × 10-3 Gy;16.8 × 10-2 Gy), and 2 years (dose rate: 144 × 10-3 Gy;67.2 × 10-2 Gy) of space flight. There have been several trials that aimed to take C. elegans into orbit on US space shuttle missions including a mission on the shuttle Columbia. In this study, we simulated longer duration space flights and performed a whole-genome microarray analysis to observe phenotype variations whereas most such experiments were carried out during short duration space flights and focused on mutations and genotypic variations. We expect that the results of this study will be useful to predict the effects of long-term exposure of space radiation on living organisms.展开更多
This paper deals with the problem of approximate controllability of infinite dimensional linear systems in nonreflexive state spaces. A necessary and sufficient condition for approximate controllability via L^p（[0, T...This paper deals with the problem of approximate controllability of infinite dimensional linear systems in nonreflexive state spaces. A necessary and sufficient condition for approximate controllability via L^p（[0, T], U）, 1≤p〈∞ is obtained,where L^p（ [0, T], U） is the control function space.展开更多
Chevkinite specimen from a rare-earth mineral deposit in Sichuan, southwest of China have been studied in detail by means of transmission electron microscope (TEM).The selected area electron diffraction (SAED)and conv...Chevkinite specimen from a rare-earth mineral deposit in Sichuan, southwest of China have been studied in detail by means of transmission electron microscope (TEM).The selected area electron diffraction (SAED)and convergent beam electron diffraction (CBED) patterns , obtained from different crystal zone axis direction , proved coincidently that the space group of chevkinite is C2/m . Fringe lattice image observation showed the mineral crystal is structurally uniform in microscale , and it is an ideal specimen for electron diffraction analysis . The mineral studied here is similar to the one from Bayan Obo , Inner Mongolia , China , in chemical composition and REE distribution . The chemical formula of the crystal is (Ce , La ,… , Ca) 4 Fe2+ (Fe, Ti, Nb) 2 O8 (Si2O7)2 From our study , we come to the conclusion that the space group of the natural chevkinite is C2/m , instead of P21/a as synthetic one . Up to now , chevkinite compositionally similar to the synthetic one , in which the complete replacements of Ce , La by Nd and Fe by Mg or Co occur , has not been discovered in nature . So we suggest that the name for synthesized chevkinite should be further discussed .展开更多
Several theorems on closed (resp. open) covering properties of H-spaces are obtained which improve and generalize the corresponding results of Sperner, Klee, Alexandroff-Pasynkoff, Berge, Ghouila-Houri, Danzer-Grunbau...Several theorems on closed (resp. open) covering properties of H-spaces are obtained which improve and generalize the corresponding results of Sperner, Klee, Alexandroff-Pasynkoff, Berge, Ghouila-Houri, Danzer-Grunbaum-Klee, Ky Fan, Shih-Tan, Horvath and Lassonde. As application an almost fixed point theorem for lower semi-continuous map in l.c.-spaces and a generalization of Tychonoffs fixed point theorem are proved in l.c.-spaces which improve those results of Ky Fan and Horvath.展开更多
文摘目的报道1例在鞍区精原细胞瘤放化疗后出现C型尼曼-匹克病(Niemann-Pick disease type C,NPC)的病例,加强对尼曼-匹克病(Niemann-Pick disease,NPD)的了解。方法对南部战区总医院内分泌科2021年6月收治的1例鞍区精原细胞瘤切除术、放化疗后逐渐出现垂体功能减退、重度肝损害、肝脾大,激素替代治疗后引起继发性糖尿病的青少年患者长达4年的病史进行回顾性分析。结果本例患者为青少年女性,鞍区精原细胞瘤切除术及放化疗后,逐渐出现不同程度血细胞下降、脂代谢异常、肝功能异常、肝脾增大等,行骨髓穿刺,形态学发现2%尼曼-匹克细胞,最终诊断为NPC。经输血、护肝、胰岛素降糖、激素替代等对症治疗后,各项指标较治疗前好转,精神较入院时稍好转,但患者仍存在黄疸、肝脾大,偶有精神异常。目前继续门诊随访,予对症治疗。结论对于颅内肿瘤术后或放化疗后所致内分泌与代谢相关症状,且同时伴有难以解释的神经、精神、脏器功能异常时,要考虑到NPC的可能性,可通过骨髓穿刺涂片发现尼曼-匹克细胞初步诊断。目前NPC的治疗以对症为主。
文摘In this paper, we give existence theorems of common fixed points for two mappings with a weakly C*-contractive condition on partially ordered 2-metric spaces and give a sufficient condition under which there exists a unique common fixed point.
文摘The degree of approximation to a function f(x)∈C[-1,1] by (U, λ) means and f(x) ∈ Lpw by (Jr) means are discussed, some results in the literatures [1],[2],[3] have been improved.
基金Supported by youth foundation of Sichuan province (1999-09)
文摘Kunio Hidano[4] has shown that the global and local C2-solutions for semilinear wave equations with spherical symmetry in three space dimensions. This paper studies the global and local C2-solutions for the semilinear wave equations without spherical symmetry in three space dimensions. A problem put forward by Hiroyuki Takamura[2] is partially answered.
文摘In this article, we introduce and investigate the concept of multivalued hybrid mappings in C AT（0） spaces by using the concept of quasilinearization. Also, we present a new iterative algorithm involving products of Moreau-Yosida resolvents for finding a common element of the set of minimizers of a finite family of convex functions and a common fixed point of two multivalued hybrid mappings in C AT（0） spaces.
文摘In this study, we simulated space flight of the nematode, Caenorhabditis elegans, on the ground and examined how it is affected by space radiation and G-forces. We simulated G-forces during launch in a gravity acceleration laboratory device in order to identify and isolate the effects of the G-forces. Following this, we irradiated C. elegans with accelerated protons (MC-50 Cyclotron) and gamma rays (iR 222 machine) at the same physical dose. We calculated the expected radiation dose according to Reitz [1] and simulation programs (NASA AP8MIN [2], NASA AE8MAX [2], and CREAM86 [3]) for 1 month (dose rate: 6 × 10-3 Gy;2.8 × 10-2 Gy), 6 months (dose rate: 36 × 10-3 Gy;16.8 × 10-2 Gy), and 2 years (dose rate: 144 × 10-3 Gy;67.2 × 10-2 Gy) of space flight. There have been several trials that aimed to take C. elegans into orbit on US space shuttle missions including a mission on the shuttle Columbia. In this study, we simulated longer duration space flights and performed a whole-genome microarray analysis to observe phenotype variations whereas most such experiments were carried out during short duration space flights and focused on mutations and genotypic variations. We expect that the results of this study will be useful to predict the effects of long-term exposure of space radiation on living organisms.
文摘This paper deals with the problem of approximate controllability of infinite dimensional linear systems in nonreflexive state spaces. A necessary and sufficient condition for approximate controllability via L^p（[0, T], U）, 1≤p〈∞ is obtained,where L^p（ [0, T], U） is the control function space.
基金Financial support for this study was provided by the Scicnce Foundation of Doctorate Program 8849104-11 from the National Committce of Education
文摘Chevkinite specimen from a rare-earth mineral deposit in Sichuan, southwest of China have been studied in detail by means of transmission electron microscope (TEM).The selected area electron diffraction (SAED)and convergent beam electron diffraction (CBED) patterns , obtained from different crystal zone axis direction , proved coincidently that the space group of chevkinite is C2/m . Fringe lattice image observation showed the mineral crystal is structurally uniform in microscale , and it is an ideal specimen for electron diffraction analysis . The mineral studied here is similar to the one from Bayan Obo , Inner Mongolia , China , in chemical composition and REE distribution . The chemical formula of the crystal is (Ce , La ,… , Ca) 4 Fe2+ (Fe, Ti, Nb) 2 O8 (Si2O7)2 From our study , we come to the conclusion that the space group of the natural chevkinite is C2/m , instead of P21/a as synthetic one . Up to now , chevkinite compositionally similar to the synthetic one , in which the complete replacements of Ce , La by Nd and Fe by Mg or Co occur , has not been discovered in nature . So we suggest that the name for synthesized chevkinite should be further discussed .
基金This project partially supported by National Natural Science Foundation of ChinaThis work was partially supported by NSERC of Canada under grant A-8096
文摘Several theorems on closed (resp. open) covering properties of H-spaces are obtained which improve and generalize the corresponding results of Sperner, Klee, Alexandroff-Pasynkoff, Berge, Ghouila-Houri, Danzer-Grunbaum-Klee, Ky Fan, Shih-Tan, Horvath and Lassonde. As application an almost fixed point theorem for lower semi-continuous map in l.c.-spaces and a generalization of Tychonoffs fixed point theorem are proved in l.c.-spaces which improve those results of Ky Fan and Horvath.
