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Do changes in intracoronary pressure aid coronary spasm diagnosis using the spasm provocation test?
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作者 Hiroki Teragawa Chikage Oshita Yuko Uchimura 《World Journal of Cardiology》 2024年第1期16-26,共11页
BACKGROUND Although the spasm provocation test(SPT)can diagnose coronary spasms,it would be helpful if it could also predict their occurrence.AIM To investigate whether coronary spasms can be predicted using changes i... BACKGROUND Although the spasm provocation test(SPT)can diagnose coronary spasms,it would be helpful if it could also predict their occurrence.AIM To investigate whether coronary spasms can be predicted using changes in intracoronary artery pressure measured using a pressure wire during the SPT.METHODS Seventy patients underwent SPTs with pressure-wire measurement of intracoronary artery pressure.During each SPT,the pressure wire was advanced into the distal portion of the right coronary artery(RCA)and left anterior descending coronary artery,and the ratio of intracoronary pressure to aortic pressure(Pd/Pa)was monitored.Coronary spasm was defined as an arterial narrowing of>90%in response to the administration of acetylcholine(ACh),with chest symptoms and/or ischemic electrocardiographic changes.ACh was administered to the RCA at low,moderate,or high doses of 20,50,or 80μg,respectively,and to the left coronary artery(LCA)at low,moderate,or high doses of 50,100,or 200μg,respectively.Coronary arteries with coronary spasms at low doses of ACh were defined as group L,and those with coronary spasms at moderate or high doses were defined as group MH.Those who did not occur coronary spasms at any ACh dose were designated as group N.RESULTS Among the 132 coronary arteries assessed using a pressure wire,there were 49 in group N,25 in group L,and 58 in group MH.Baseline Pd/Pa was the lowest in group L(P=0.001).The decrease in the Pd/Pa between baseline to low doses of ACh was lower in group MH than in group N(P<0.001).A receiver-operating characteristics analysis showed that the cutoff baseline Pd/Pa value for predicting group L was 0.95,with a sensitivity of 0.600(15/25)and a specificity of 0.713(76/107)and that the cutoff value of Pd/Pa from baseline to low doses of ACh for predicting group MH was−0.04,with a sensitivity of 0.741(43/58)and a specificity of 0.694(34/49).CONCLUSION These findings suggest that indices of intracoronary pressure during SPT may be useful means for predicting the occurrence of coronary spasms. 展开更多
关键词 ACETYLCHOLINE Coronary spasm Intracoronary pressure Pressure wire spasm provocation test Vasospastic angina
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Mechanism of acupuncture for limb spasm of post-stroke spasticity based on GABA and BDNF/Trkb-KCC2 signaling pathway
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作者 Qiong-Shuai Zhang Yi Li +2 位作者 Yu Zhang Yu-Feng Wang Bai-Lin Song 《Traditional Medicine Research》 2024年第7期42-48,共7页
Background:To investigate the effects of acupuncture on post-stroke limb spasm model rats and the underlying mechanism.Methods:A total of 50 Sprague-Dawley rats were randomly divided into three groups,Control group(10... Background:To investigate the effects of acupuncture on post-stroke limb spasm model rats and the underlying mechanism.Methods:A total of 50 Sprague-Dawley rats were randomly divided into three groups,Control group(10),Model group(20)and Zhishen Tiaoxing(ZSTX)acupuncture group(20).Middle cerebral artery occlusion was conducted in SD rats to establish post-stroke limb spasm rats,which were treated with ZSTX acupuncture.Behavioral assays were determined by the Narrow ally test,the limb muscle tension was detected by the BL-420S test system,and infarct volume was assessed after the cerebral infarction by 2,3,5-triphenyltetrazolium chloride staining.Heterogeneous neurotransmitterγ-aminobutyric acid(GABA)and its receptors GABAA and GABAB in the cerebral cortex of the infarct area were determined by immunofluorescence assay.The release of Trkb and K-Cl cotransporter isoform 2 was detected by an immunofluorescence double labeling study.Western Blot was utilized to measure the expression of BDNF and Trkb.Results:The results showed that the behavioral assays in post-stroke limb spasm rats were significantly improved by the treatment of ZSTX acupuncture.14 days of ZSTX acupuncture can effectively inhibit muscle tone and decrease Infarct volume,which was measured with BL-420S biological function experiment system and triphenyltetrazolium chloride.Meanwhile,the results of Double-Label Immunofluorescence Assays showed that ZSTX acupuncture improved the expression of GABA,GABAA,GABAB,BDNF,and K-Cl cotransporter isoform 2.Double-Label Immunofluorescence Assays and WB results showed that 14 days ZSTX acupuncture declined the expression of Trkb.Conclusions:Our results suggest that 14 days of ZSTX acupuncture can significantly improve post-stroke limb spasm.Meanwhile,the pathogenesis of post-stroke limb spasm and the efficacy of ZSTX acupuncture involve metabolic pathways of neurotransmitters,and electro-acupuncture can treat post-stroke limb spasm by regulating BDNF/Trkb-KCC2 signaling pathway. 展开更多
关键词 ACUPUNCTURE scalp acupuncture limb spasm of post-stroke
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TREATMENT OF FACIAL SPASM BY PLUM-BLOSSOM NEEDLE TAPPING AND CUPPING THERAPY 被引量:1
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作者 陆汎 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1993年第3期203-204,共2页
Facial spasm is a frequently seen dis-ease characterized by unilateral involuntaryirregular twitching of the facial muscles.This disorder may be induced by intoxica-tion,infection,trauma and long-term facialparalysis ... Facial spasm is a frequently seen dis-ease characterized by unilateral involuntaryirregular twitching of the facial muscles.This disorder may be induced by intoxica-tion,infection,trauma and long-term facialparalysis which was not properly treated. 展开更多
关键词 FACIAL PROPERLY muscles UNILATERAL trauma spasm ANGER bright talking Kidney
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Rehabilitation therapy centralized on facilitation and acupuncture on upper extremities spasm after stroke 被引量:3
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作者 屈云 盛敏 +3 位作者 蒋毅 熊淑芳 何成奇 罗祖明 《中国临床康复》 CSCD 2003年第1期136-136,共1页
AIM: To observe the therapeutic effect of rehabilitation therapy centralized on facilitation and acupuncture on upper extremities spasm after stroke.METHODS:56 cases of stroke patients with upper extremities spasm wer... AIM: To observe the therapeutic effect of rehabilitation therapy centralized on facilitation and acupuncture on upper extremities spasm after stroke.METHODS:56 cases of stroke patients with upper extremities spasm were divided into two groups by random.28 patients in treatment group were received rehabilitation therapy centralized on facilitation and acupuncture treatment.Others in control group were received traditional method. RESULT:All patients were evaluated by muscle tone evaluation of Ashworth Scale.The outcomes of two groups had significant different (P< 0.01). CONCLUSION:We could archive the satisfactory effects with acupuncture and rehabilitation therapy centralized on facilitation on upper extremities spasm of stroke patients. 展开更多
关键词 脑卒中 上肢痉挛 易化技术 针灸疗法 治疗
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OBSERVATION ON CLINICAL THERAPEUTIC EFFECTS OF SCALP ACUPUNCTURE FOR FACIAL SPASM 被引量:1
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作者 王顺 蔡玉颖 +1 位作者 尚艳杰 桑鹏 《World Journal of Acupuncture-Moxibustion》 2005年第4期37-39,共3页
Objective; To observe clinical therapeutic effect of scalp acupuncture in the treatment of facial spasm. Methods: Sixty-five cases of facial spasm were randomly divided into control group (n = 31 ) and treatment gr... Objective; To observe clinical therapeutic effect of scalp acupuncture in the treatment of facial spasm. Methods: Sixty-five cases of facial spasm were randomly divided into control group (n = 31 ) and treatment group(n = 34). Patients of the treatment group were treated with penetrative acupuncture from Qienshencong(前神聪 Extra) to Xuanli(悬厘 GB 6), Baihui(百会 GV 20) to Qubin(曲鬓 GB 7), etc., and those of control group treated with acupuncture of Taiyang(太阳 EX-HN 5), Yengbai(阳白 GB 14), Quanliao(颧髎 SI 18) and Xiaguan(下关 ST 7), etc. once daily, 20 sessions altogether. Results. After treatment, of the 31 cases and 34 cases in control and treatment groups, 5 and 12 were cured, 8 and 13 had remarkable improvement, 11 and 8 had improvement, 7 and 1 failed, with the total effective rates being 77.42% and 97.06% respectively; and the therapeutic elfact of treatment group was significantly superior to that of control group(P〈0.01). Conclusion; Scalp acupurcture has an obvious therapeutic effect for facial spasm. 展开更多
关键词 Facial spasm Acupuncture therapy Scalp acupuncture
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OBSERVATION ON THERAPEUTIC EFFECT OF LOCAL SELECTION OF POINTS COMBINED WITH ABDOMINAL ACUPUNCTURE FOR FACIAL SPASM 被引量:1
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作者 张晓阳 《World Journal of Acupuncture-Moxibustion》 2006年第4期3-6,共4页
Objective To observe the therapeutic effect of local selection of points combined with abdominal acupuncture in the treatment of facial spasm. Methods Eighty cases of facial spasm were randomly divided into treatment ... Objective To observe the therapeutic effect of local selection of points combined with abdominal acupuncture in the treatment of facial spasm. Methods Eighty cases of facial spasm were randomly divided into treatment group and control group, 40 cases in each group,treated respectively by abdominal acupuncture combined with local selected points and local points simply. After 30 sessions of treatment, the therapeutic effect was evaluated. Results In the treatment group, the total effective rate reached 92.5%, the curative rate 75.0%; while in the control group, the total effective rate was 80.0%, the curative rate 55.0% with a significant difference between the two groups ( P<0.05 ). Conclusion The therapeutic effect of abdominal acupuncture combined with local points is superior to that of simple local selection of points in the treatment of facial spasm. 展开更多
关键词 Muscular spasm Acupuncture therapy Abdominal acupuncture
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Intraoperative cardiogenic shock induced by refractory coronary artery spasm in a patient with myasthenia gravis: A case report 被引量:1
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作者 Cheng-Wei Hsu Chuen-Chau Chang Chao-Shun Lin 《World Journal of Clinical Cases》 SCIE 2023年第36期8589-8594,共6页
BACKGROUND Coronary artery spasm(CAS)is a rare but critical condition during surgery.Clinical manifestations can vary from only subtle electrocardiography change to sudden death.In this case report,we present the case... BACKGROUND Coronary artery spasm(CAS)is a rare but critical condition during surgery.Clinical manifestations can vary from only subtle electrocardiography change to sudden death.In this case report,we present the case of a patient with myasthenia gravis(MG)who developed refractory CAS-related cardiogenic shock during thymoma surgery.CASE SUMMARY A 61-year-old man had a history of cigarette smoking and coronary artery disease with a bare metal stent placed.Three months ago,he suffered from coronary spasms,with three vessels involved,after surgery for cervical spine injury.He started having progressive dysphagia 4 wk prior and was diagnosed with MG via serologic tests,and computed tomography declared a thymoma in the anterior mediastinum.After the symptoms of MG subsided,he was referred for thy-mectomy.The operation was uneventful until the closing of the sternal wound.Electrocardiography showed sudden onset ST elevation,followed by ventricular tachycardia and severe hypotension.Cardiopulmonary cerebral resuscitation was initiated immediately with electrical defibrillation,extracorporeal membrane oxygenation was performed due to refractory cardiogenic shock,and the patient was transferred to an angiography room.Angiography showed diffuse CAS with three vessels involved.Intracoronary isosorbide dinitrate and adenosine were administered,and then the patient was transferred to the intensive care unit.CONCLUSION Our case highlights the importance of being prepared for clinical situations such as the one described here and suggests the necessity of developing an appropriate anesthesia plan that includes proactive analgesia and preemptive coronary vaso-dilators. 展开更多
关键词 Coronary spasm Myasthenia gravis THYMECTOMY Shock Case report
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Does the intracoronary pressure differ according to two types(diffuse or focal)of coronary spasm? 被引量:1
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作者 Hiroki Teragawa Chikage Oshita Yuko Uchimura 《World Journal of Cardiology》 2023年第1期1-12,共12页
BACKGROUND Several reports show that two types of coronary vasospasm(diffuse and focal spasm)are associated with the severity or prognosis of coronary spasm in patients with vasospastic angina(VSA).It is unclear wheth... BACKGROUND Several reports show that two types of coronary vasospasm(diffuse and focal spasm)are associated with the severity or prognosis of coronary spasm in patients with vasospastic angina(VSA).It is unclear whether intracoronary pressure differs between the two spasm types.AIM To investigate such relationships using a pressure wire during the spasm provocation test(SPT)in patients with VSA.METHODS Eighty-seven patients with VSA(average age:67 years;50 men,37 women)underwent SPT.During the SPT,a pressure wire was advanced into the distal portion of the right coronary artery and left anterior descending coronary artery,and the ratio of the intracoronary pressure to the aortic pressure(Pd/Pa)was continuously monitored.An SPT was performed using acetylcholine(ACh),and the presence of coronary spasm was defined as the presence of>90%arterial narrowing in response to an ACh infusion,with the usual chest symptoms and/or ischemic ECG changes.Focal spasm was defined as total or subtotal spasm within one segment of the AHA classification,while diffuse spasm was defined as>90%spasm with two or more segments.RESULTS Among 87 patients,the frequencies of metabolic syndrome and having coronary atherosclerosis were higher in the focal group(n=33)than in the diffuse spasm group(n=54,P<0.05).In the vessel analyses,in these 134 spastic segments,diffuse and focal spasms were detected in 100 and 34 vessels,respectively.The Pd/Pa at baseline was similar in both groups(diffuse:0.96±0.05,focal:0.95±0.05,P=0.35);however,the Pd/Pa during coronary spasm was lower in focal spastic vessels(0.66±0.20)than in diffuse spastic vessels(0.76±0.11,P<0.01),and the reduction in Pd/Pa during an SPT was also lower in focal spastic vessels(-0.29±0.20)than in diffuse spastic vessels(-0.18±0.11,P<0.01).The presence of focal spasm was a significant factor responsible for reduction in Pd/Pa during SPT.CONCLUSION These findings suggest that focal spasm may be more severe than diffuse spasm,judging from the intracoronary pressure during coronary spasm. 展开更多
关键词 ACETYLCHOLINE Intracoronary pressure Diffuse or focal spasm Vasospastic angina
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Fire needle combined with filiform needle therapy for hemifacial spasm: a case report
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作者 Kai-Jun Zhang Jia-Chun Xu Zhen Zhou 《TMR Non-Drug Therapy》 2018年第2期44-47,共4页
Objective: Hemifacial spasm (HFS) is characterized by involuntary unilateral contractions of the muscles, usually starting around the eyes before progressing inferiorly to the cheek, mouth, and neck. Here we descr... Objective: Hemifacial spasm (HFS) is characterized by involuntary unilateral contractions of the muscles, usually starting around the eyes before progressing inferiorly to the cheek, mouth, and neck. Here we described the use of fire needle combined with filiform needle for a patient with HFS on the left face. Methods: The fire needle was inserted into the points of Du meridian and the first lateral line of bladder meridian, combined with the points of the Ashi points around the left eye, Guanyuan (CV 4), Qihai (CV 6), Xiawan (CV 10), Zhongwan (CV 12), Tianshu (ST 25), Guilai (ST 29) and Daheng (SP 15). The filiform needle was used to acupuncture the points located on the left side of face including Cuanzhu (BL 2), Tongziliao (GB 1), Yangbai (GB 14), Fengchi (GB 20), Sizhukong (TE 23) and Sibai (ST 2). Results: The patient received the combined therapy of fire needle and filiform needle for 9 times in 5 weeks. After that, the symptoms of dull sensation in the left facial area and the twitching of the muscles of the left eye were improved remarkably. Conclusions: The fire needle combined with filiform needle therapy has the potential to cure HFS. 展开更多
关键词 Hemifacial spasm Fire needle Filiform needle
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Comparative analysis of Parikartika and Anal Fissure: unraveling diagnostic, therapeutic, and surgical dimensions
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作者 Sandeep Kumar Upadhyay Sheetal Asutkar Shreya Soni 《Clinical Research Communications》 2023年第4期1-9,共9页
Background:Agnimandya,the underlying cause of anorectal disorders,of which Parikartika is the most well-known,is brought on by lifestyles characterized by sedentary behavior,elevated stress,poor nutrition,and sleep ha... Background:Agnimandya,the underlying cause of anorectal disorders,of which Parikartika is the most well-known,is brought on by lifestyles characterized by sedentary behavior,elevated stress,poor nutrition,and sleep habits.The illness known as Parikartika,with signs and symptoms like fissure-in-ano in modern sources,is characterized by kartanvat Vedana(cutting pain)over the anal region.Acute fissure-in-ano is treated with analgesics,stool softeners,and soothing creams.Treatment options for hazy chronic fissures include anal dilatation,sphincterotomy,fissurectomy,and anal advancement flap.In addition to using laxatives and substances that promote wound healing(vranaropaka),the concepts of management of Parikartika in Ayurveda are more heavily weighted towards enhancing the nature,character,and consistency of stool and stabilizing the digestive functions Parikartika is mentioned in Ayurvedic texts as a complication of many Ayurvedic procedures,such as Vamana,Virechana,and Basti,as well as a complication of some disorders,such as Arsh,Atisar,and Grahani.Aim and objective:This article aims to comprehensively review the literature,diagnostic,and therapeutic aspects of Parikartika,with its correlation to Fissure in ano,and compare the clinical outcomes of the treatment modalities with supporting references,consolidating all pertinent information on the subject.Material&method:Collection from Samhita’s,commentaries,exploring medical websites,Ayurvedic journals related to the topic of Parikartika and fissure in ano,systematic record of the collected literature and a summary of each item.Organize the collected materials,reference and citation are the material and method followed here.Discussion&conclusion:This is an extensive literature review on Parikartika in Ayurveda,exploring its contemporary association with Fissure in Ano.The research offers insights that can inform the evaluation and treatment of this condition,considering both conservative and surgical approaches,thereby enhancing clinical management strategies. 展开更多
关键词 ANORECTAL botulinum toxin Anal fissure anal spasm sentinel tag Gudaparikartika SPHINCTEROTOMY
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电针对脑出血后偏瘫痉挛大鼠脊髓颈膨大处GluR2表达的影响
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作者 任慧玲 卢旭东 +4 位作者 赵庆林 赵大巍 郭荣彬 李常法 步玮 《现代中西医结合杂志》 CAS 2024年第3期316-321,共6页
目的研究电针经穴对脑出血后偏瘫痉挛大鼠脊髓颈膨大处谷氨酸受体2(GluR2)表达的影响,探讨电针缓解脑出血后偏瘫痉挛症状的机制。方法将45只健康SD大鼠随机分为假手术组9只、模型组18只、电针组18只。模型组和电针组大鼠采用立体定向在... 目的研究电针经穴对脑出血后偏瘫痉挛大鼠脊髓颈膨大处谷氨酸受体2(GluR2)表达的影响,探讨电针缓解脑出血后偏瘫痉挛症状的机制。方法将45只健康SD大鼠随机分为假手术组9只、模型组18只、电针组18只。模型组和电针组大鼠采用立体定向在右侧内囊注入自体尾血方法建立脑出血模型,假手术组大鼠不注射自体尾血。造模后电针组采用电针刺激大鼠曲池与足三里穴,假手术组与模型组不给予任何干预。术后第3天、第7天对大鼠分别进行行为学检测[神经功能状态(采用Zea-longa评分评定)、肌张力(采用改良的Ashworth分级评分测定)、旷场实验],并采用Western blot法和免疫组化法检测脊髓颈膨大处GluR2表达情况。结果术后第3天、第7天与假手术组比较,模型组大鼠的Zea-longa评分和左前肢、左后肢的改良Ashworth评分均明显增高(P均<0.05),运动总路程明显缩短(P均<0.05),平均速度明显减慢(P均<0.05),静止时间明显延长(P均<0.05),脊髓颈膨大处GluR2蛋白相对表达量和阳性表达平均光密度值均明显降低(P均<0.05)。与模型组比较,电针组大鼠的Zea-longa评分和左前肢、左后肢的改良Ashworth评分均明显降低(P均<0.05),运动总路程明显延长(P均<0.05),平均速度明显加快(P均<0.05),静止时间明显缩短(P均<0.05),脊髓颈膨大处GluR2蛋白相对表达量和阳性表达平均光密度值均明显增高(P均<0.05)。结论电针刺激曲池和足三里穴可以显著改善脑出血大鼠痉挛性瘫痪症状,缓解肌张力增高,上调脊髓颈膨大处GluR2表达可能是电针治疗缓解脑出血后肢体痉挛的机制之一。 展开更多
关键词 电针 脑出血 偏瘫 痉挛 脊髓 谷氨酸受体2
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督脉电针调控胱氨酸/谷氨酸反向转运体改善脑卒中后肢体痉挛的作用机制
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作者 张丽红 李瑞青 +4 位作者 王艺莹 梅紧紧 苏凯奇 顾昌宇 黄梦玲 《天津医药》 CAS 2024年第5期463-468,共6页
目的探讨督脉电针对大脑中动脉阻塞再灌注(MCAO/R)后肢体痉挛大鼠大脑皮质中胱氨酸/谷氨酸反向转运体[System Xc(-)]的影响,并探讨其可能的作用机制。方法选择SPF级雄性SD大鼠60只,随机分为空白组、假手术组及造模组。空白组不进行任何... 目的探讨督脉电针对大脑中动脉阻塞再灌注(MCAO/R)后肢体痉挛大鼠大脑皮质中胱氨酸/谷氨酸反向转运体[System Xc(-)]的影响,并探讨其可能的作用机制。方法选择SPF级雄性SD大鼠60只,随机分为空白组、假手术组及造模组。空白组不进行任何处理,假手术组仅分离血管,造模组采用大脑中动脉栓塞法制备MCAO/R大鼠模型,并于术后第3天进行Zea-Longa神经功能缺损评分、肌张力评定和电生理描记检测筛选肢体痉挛大鼠,造模组造模成功后随机分为模型组和督脉电针组。其中,督脉电针组于术后第3天开始治疗,每日1次,每次30 min,连续7 d。治疗结束后再次评定其神经功能及肌张力恢复情况;TTC染色测算脑梗死体积;干湿质量法检测各组大鼠脑含水量;比色法检测大脑皮质中谷氨酸(Glu)、半胱氨酸(Cys)和谷胱甘肽(GSH)浓度;蛋白免疫印迹(Western blot)法和实时荧光定量PCR(RT-qPCR)分别从蛋白和基因水平检测大脑皮质中血清溶质载体家族7成员11(SLC7A11)、溶质转运蛋白家族3成员2(SLC3A2)、γ-谷氨酰半胱氨酸合酶(γ-GCS)和谷胱甘肽合成酶(GSS)的表达。结果与模型组相比,治疗后督脉电针组大鼠神经功能缺损评分和改良Ashworth评分降低,肌电信号值增强,脑水肿程度减轻,脑梗死程度有所恢复,Cys和GSH含量显著增加,SLC7A11、SLC3A2、γ-GCS和GSS蛋白和mRNA的表达量显著提高,而Glu浓度显著降低(P<0.05)。结论督脉电针可以改善脑卒中后大鼠神经功能损伤和肢体痉挛程度,其机制可能与调控System Xc(-),改善Glu兴奋性毒性和氧化应激有关。 展开更多
关键词 卒中 痉挛 督脉电针 胱氨酸/谷氨酸反向转运体
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神经电生理监测下MVD术对面肌痉挛患者临床疗效及并发症的影响
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作者 孟恩平 马艳 +3 位作者 付旭东 马建 张恒威 李明贺 《黑龙江医学》 2024年第11期1311-1313,共3页
目的:探究神经电生理监测下微血管减压(MVD)术对面肌痉挛(HFS)患者的临床治疗效果以及并发症的影响。方法:选取2016年5月—2021年6月郑州大学第五附属医院收治的78例HFS患者作为研究对象,按随机数表法分为对照组(39例)与监测组(39例)。... 目的:探究神经电生理监测下微血管减压(MVD)术对面肌痉挛(HFS)患者的临床治疗效果以及并发症的影响。方法:选取2016年5月—2021年6月郑州大学第五附属医院收治的78例HFS患者作为研究对象,按随机数表法分为对照组(39例)与监测组(39例)。两组患者均给予MVD术进行治疗,监测组患者在实施MVD术中进行神经电生理监测。观察监测组患者面神经侧方扩散反应(LSR)情况以及脑干听觉诱发电位(BAEP)中的V波情况,比较两组患者术后临床治疗效果以及术后并发症发生情况。结果:通过对监测组患者在MVD术中进行神经电生理监测发现,其中有5例患者LSR波形消失是在进行桥小脑角探测检查时,32例患者是在进行神经减压时消失,其余2例患者直至MVD手术结束LSR波形仍然可见。术后1 d,监测组患者治疗总有效率较对照组更高,差异有统计学意义(P<0.05);监测组患者并发症总发生率较对照组更低,差异有统计学意义(χ^(2)=22.675,P<0.05)。结论:HFS患者在神经电生理监测下实施MVD术进行治疗,临床治疗效果较为显著,同时,患者的并发症发生情况较少,比临床治疗HFS患者时单独采用MVD术进行治疗的方式更具优势,值得临床借鉴参考。 展开更多
关键词 神经电生理监测 微血管减压 面肌痉挛 临床疗效
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基于3D Slicer的多模态影像融合技术及神经电生理监测在面肌痉挛微血管减压术中的应用
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作者 刘文浩 叶敏 +2 位作者 张文波 梁明礼 范伟雄 《中国实用神经疾病杂志》 2024年第8期1033-1036,共4页
目的探讨基于3D Slicer的多模态影像融合技术及神经电生理监测在面肌痉挛微血管减压术中的应用价值。方法采用回顾性分析法,选取41例行血管减压术的面肌痉挛患者为研究对象。术前通过3D Slicer软件对责任血管进行多模态影像融合分析,确... 目的探讨基于3D Slicer的多模态影像融合技术及神经电生理监测在面肌痉挛微血管减压术中的应用价值。方法采用回顾性分析法,选取41例行血管减压术的面肌痉挛患者为研究对象。术前通过3D Slicer软件对责任血管进行多模态影像融合分析,确定手术方案,术中进行神经电生理监测以判断减压。观察手术效果并追踪术后复发情况。结果术前建模图像发现40例存在微血管压迫,1例未见微血管压迫。未见微血管压迫的1例经术中证实为岩静脉压迫,1例小脑前下动脉经术中证实为小脑上动脉,其余责任血管判定均与术中所见一致。术前建模图像的责任血管判定正确39例,正确率为95%。41例患者经手术治疗后症状均完全缓解,完全缓解率为100%。术后住院期间1例发生面瘫,1例发生听力下降,经对症处理后很快缓解,术后随访3~36个月无复发。结论在面肌痉挛微血管减压术中联合应用多模态影像融合技术可直观了解责任血管及周围重要结构解剖情况,配合神经电生理监测可避免术中减压过度或不充分的情况,两项技术的联合应用可有效提高手术疗效。 展开更多
关键词 微血管减压术 多模态影像融合 神经电生理监测 面肌痉挛 责任血管 磁共振成像
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神经肌肉电刺激系统联合康复训练在脑卒中后肢体功能障碍患者康复中的应用价值
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作者 甘艺红 汪婷 +4 位作者 陈陪能 陈苗 张艺羡 黄雪娟 张秀霞 《中国医学创新》 CAS 2024年第27期118-122,共5页
目的:探究神经肌肉电刺激系统联合康复训练在脑卒中后肢体功能障碍患者康复中的应用价值。方法:选取2022年1—12月第九〇九医院收治的95例脑卒中后肢体功能障碍患者作为研究对象。按照随机数字表法分为对照组(n=47)和观察组(n=48)。观... 目的:探究神经肌肉电刺激系统联合康复训练在脑卒中后肢体功能障碍患者康复中的应用价值。方法:选取2022年1—12月第九〇九医院收治的95例脑卒中后肢体功能障碍患者作为研究对象。按照随机数字表法分为对照组(n=47)和观察组(n=48)。观察组行康复训练联合神经肌肉电刺激系统干预,对照组仅接受康复训练干预,两组均持续干预3个月。比较两组干预前后改良Ashworth量表(MAS)评分、患肢各关节主动活动度、脑卒中康复运动功能评定量表(STREAM)评分。结果:干预前,两组MAS评分、患肢各关节主动活动度、STREAM评分比较,差异均无统计学意义(P>0.05);干预后,两组患侧上肢肌肉痉挛、下肢肌肉痉挛评分均低于干预前,且观察组均低于对照组,差异均有统计学意义(P<0.05);干预后,两组肩关节外展、肘关节屈曲、腕关节掌屈、手掌指关节屈曲、髋关节内外旋、膝关节屈伸主动活动度均高于干预前,且观察组均高于对照组,差异均有统计学意义(P<0.05)。干预后,两组上肢运动、下肢运动、基本活动评分及总分均高于干预前,且观察组均高于对照组,差异均有统计学意义(P<0.05)。结论:在脑卒中后肢体功能障碍患者康复中应用神经肌肉电刺激系统联合康复训练可以有效缓解其肌肉痉挛情况,改善关节活动度,提高肢体运动功能。 展开更多
关键词 神经肌肉电刺激系统 脑卒中 肢体功能障碍 康复训练 肌肉痉挛 关节活动度 运动功能
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改良中药蜡疗在痉挛型脑瘫尖足患儿中的应用
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作者 白青云 赵伟霞 +4 位作者 张建奎 马丙祥 谢克功 娄元俊 魏晨曦 《光明中医》 2024年第11期2232-2235,共4页
目的探讨改良中药蜡疗对痉挛型脑瘫尖足患儿的临床疗效。方法选取72例痉挛型脑瘫尖足患儿作为研究对象,采用随机数字表法分为观察组和对照组,各36例。对照组在常规综合康复治疗基础上采用传统中药蜡疗,观察组在常规综合康复治疗基础上... 目的探讨改良中药蜡疗对痉挛型脑瘫尖足患儿的临床疗效。方法选取72例痉挛型脑瘫尖足患儿作为研究对象,采用随机数字表法分为观察组和对照组,各36例。对照组在常规综合康复治疗基础上采用传统中药蜡疗,观察组在常规综合康复治疗基础上采用改良中药蜡疗,分别于治疗前、治疗8周后,分析踝关节被动活动范围(PROM)、综合痉挛量表(CSS)与粗大运动功能测试量表(GMFM)评分,对2组患儿PROM值、痉挛程度,站立、行走、跑、跳功能进行评定。结果干预后观察组PROM值、GMFM中D、E功能区评分高于对照组,CSS评分低于对照组,差异均有统计学意义(P<0.01)。结论改良中药蜡疗能有效增加痉挛型脑瘫尖足患儿的踝关节被动活动范围、改善痉挛程度,提高站立、行走、跑、跳功能。 展开更多
关键词 经筋病 脑性瘫痪 痉挛 中药蜡疗 尖足
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环跳穴治疗卒中后下肢伸肌痉挛的临床体会
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作者 陈翔 胡万春 刘星 《中医药学报》 CAS 2024年第3期52-55,共4页
本文立足于《标幽赋》“中风环跳而宜刺”理论,并结合下肢伸肌痉挛病位在经筋,脏腑归于肝肾,病性属本虚标实及阳急阴缓的病机特点,阐述环跳穴治疗卒中后下肢伸肌痉挛的理论基础,同时结合医案,总结临床体会,为环跳穴治疗卒中后下肢伸肌... 本文立足于《标幽赋》“中风环跳而宜刺”理论,并结合下肢伸肌痉挛病位在经筋,脏腑归于肝肾,病性属本虚标实及阳急阴缓的病机特点,阐述环跳穴治疗卒中后下肢伸肌痉挛的理论基础,同时结合医案,总结临床体会,为环跳穴治疗卒中后下肢伸肌痉挛提高临床疗效提供临床经验。 展开更多
关键词 环跳穴 卒中 下肢伸肌痉挛
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冠状动脉痉挛非药物治疗的研究进展
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作者 张冬梅(综述) 黄颖(审校) 《现代医药卫生》 2024年第8期1400-1403,共4页
冠状动脉痉挛(CAS)经药物治疗后大多预后良好,但高危痉挛如合并冠状动脉器质性狭窄、左主干痉挛、多支血管痉挛、痉挛致猝死等类型可能需要采用非药物治疗手段。目前,CAS的非药物治疗方式包括冠状动脉介入治疗、交感神经切除术、心肌桥... 冠状动脉痉挛(CAS)经药物治疗后大多预后良好,但高危痉挛如合并冠状动脉器质性狭窄、左主干痉挛、多支血管痉挛、痉挛致猝死等类型可能需要采用非药物治疗手段。目前,CAS的非药物治疗方式包括冠状动脉介入治疗、交感神经切除术、心肌桥松解术等,但非药物治疗方式的临床适应证及远期效果均不明确。该文就CAS的非药物治疗研究进展进行了综述。 展开更多
关键词 冠状动脉痉挛 变异型心绞痛 非药物治疗 综述
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磁共振成像评价颅神经血管压迫综合征研究进展
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作者 冯晨 刘政 +5 位作者 宫雪梅 张晓鹏 毕博昊 程琳 穆实 朱敏 《中国医学创新》 CAS 2024年第20期168-173,共6页
颅神经血管压迫综合征常见的表现有三叉神经痛(trigeminal neuralgia,TN)、面肌痉挛(hemifacial spasm,HFS)等,卡马西平和奥卡西平是长期治疗的首选药物,而微血管减压术(microvacular decompression,MVD)是难治性患者的一线手术,是解除... 颅神经血管压迫综合征常见的表现有三叉神经痛(trigeminal neuralgia,TN)、面肌痉挛(hemifacial spasm,HFS)等,卡马西平和奥卡西平是长期治疗的首选药物,而微血管减压术(microvacular decompression,MVD)是难治性患者的一线手术,是解除血管压迫神经的有效方式。术前磁共振成像可以观察受累神经的解剖结构、责任血管的来源及状态,显示血管与神经的走行关系。使用特定的磁共振序列作为颅神经血管压迫综合征诊断检查的一部分,可以检测可能的神经血管接触并排除继发原因,同时神经血管接触的证明可用于促进手术决策。本文基于磁共振成像对颅神经血管压迫综合征相关病理机制、临床表现、解剖基础及高分辨率磁共振成像序列和多模态交互式磁共振成像技术研究进展进行综述,旨在为临床诊治提供影像学依据,为患者减轻病痛,减少术中并发症发生,改善患者预后。 展开更多
关键词 颅神经血管压迫综合征 面肌痉挛 三叉神经痛 微血管减压术
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腕关节机器人联合局部振动对脑卒中后腕关节痉挛的疗效观察
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作者 徐丹妮 金鑫 +5 位作者 孙亚 朱美红 陆晶晶 陈灵慧 傅建明 李岩 《浙江临床医学》 2024年第8期1162-1164,共3页
目的探讨腕关节机器人联合局部振动对脑卒中后腕关节痉挛的疗效。方法选择2021年1月至2023年4月脑卒中伴腕关节痉挛患者90例,采用随机数字表法分为腕关节机器人联合局部振动组(A组)、局部振动组(B组),常规治疗组(C组),各30例。治疗8周后... 目的探讨腕关节机器人联合局部振动对脑卒中后腕关节痉挛的疗效。方法选择2021年1月至2023年4月脑卒中伴腕关节痉挛患者90例,采用随机数字表法分为腕关节机器人联合局部振动组(A组)、局部振动组(B组),常规治疗组(C组),各30例。治疗8周后,比较三组患者治疗前后腕关节主动关节活动度(AROM)、改良Ashworth量表(MAS)、Fugl-Meyer评估量表(FMA)和改良Barthel指数(MBI)。结果三组患者治疗后AROM、Ashworth、FMA和MBI比较,差异有统计学意义(P<0.05),且A组疗效明显优于B组和C组。结论采用腕关节机器人联合局部振动对脑卒中后腕关节痉挛的患者进行干预,可明显降低患者腕关节的痉挛程度,提高腕关节的活动能力。 展开更多
关键词 腕关节机器人 局部振动 脑卒中 痉挛
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