Brillouin spectroscopy is an emerging tool for microscopic optical imaging as it allows for non-invasive and direct assessment of the viscoelastic properties of materials.Recent advances of background-free confocal Br...Brillouin spectroscopy is an emerging tool for microscopic optical imaging as it allows for non-invasive and direct assessment of the viscoelastic properties of materials.Recent advances of background-free confocal Brillouin spectrometer allows investigators to acquire the Brillouin spectra for turbid samples as well as transparent ones.However,due to strong signal loss induced by the imperfect optical setup,the Brillouin photons are usually immersed in background noise.In this report,we proposed and experimentally demonstrated multiple approaches to enhance the signal collction eficiency.A signal enhancement by>4 times can be observed,enabling ob-servation of ultra-weak signals.展开更多
基金supported by the start-up funds available through Texas A&M Universitysupport of the NIH (Grant#R21EB011703) and the NSF (ECCS Grant#10665620,DBI Grant#10665621 and CBET Grant#10665623).
文摘Brillouin spectroscopy is an emerging tool for microscopic optical imaging as it allows for non-invasive and direct assessment of the viscoelastic properties of materials.Recent advances of background-free confocal Brillouin spectrometer allows investigators to acquire the Brillouin spectra for turbid samples as well as transparent ones.However,due to strong signal loss induced by the imperfect optical setup,the Brillouin photons are usually immersed in background noise.In this report,we proposed and experimentally demonstrated multiple approaches to enhance the signal collction eficiency.A signal enhancement by>4 times can be observed,enabling ob-servation of ultra-weak signals.
