This paper discusses and studies the composition and characteristics of biospeckle on the surface of bone tissues.We used a laser speckle device to capture biospeckle patterns from fresh pig bone tissue.Traditional sp...This paper discusses and studies the composition and characteristics of biospeckle on the surface of bone tissues.We used a laser speckle device to capture biospeckle patterns from fresh pig bone tissue.Traditional speckle activity metrics were used to measure the speckle activity of ex vivo bone tissue over time.Both Gaussian and Lorentzian correlation functions were used to char-acterize the ordered and disordered motion of the bone surface,together with volume scattering,to construct the model.Using the established mathematical model of the spatio-temporal evo-lution of the biospeckle pattern,it is possible to account for the presence of volume scattering from the biospeckle of bones,quantify the ordered or disordered motions in the biological speckle activity at the current time,and assess the ability of laser speckle correlation technique to determine biological activity.展开更多
When a surface is illuminated by laser,the field of diffusing reflective light can be described by Fresnel-Kirchhoff integration in the region of Fresnel.If the correlation,before and after the change of intensity fie...When a surface is illuminated by laser,the field of diffusing reflective light can be described by Fresnel-Kirchhoff integration in the region of Fresnel.If the correlation,before and after the change of intensity field,is analysed by statistical method,three governing equations for variations of intensity field and speckle movement formulas can be obtained.In these equations,the surface motion,deformation and wavelength change are all considered to cause the speckle movement.展开更多
基金This research is supported by the National Natural Science Foundation of China(51975116)Natural Science Foundation of Shanghai(21ZR1402900)the Fundamental Research Funds for the Central Universities and Graduate Student Innovation Fund of Donghua University(CUSF-DH-D-2021057).
文摘This paper discusses and studies the composition and characteristics of biospeckle on the surface of bone tissues.We used a laser speckle device to capture biospeckle patterns from fresh pig bone tissue.Traditional speckle activity metrics were used to measure the speckle activity of ex vivo bone tissue over time.Both Gaussian and Lorentzian correlation functions were used to char-acterize the ordered and disordered motion of the bone surface,together with volume scattering,to construct the model.Using the established mathematical model of the spatio-temporal evo-lution of the biospeckle pattern,it is possible to account for the presence of volume scattering from the biospeckle of bones,quantify the ordered or disordered motions in the biological speckle activity at the current time,and assess the ability of laser speckle correlation technique to determine biological activity.
基金The project supported by National Natural Science Foundation of China
文摘When a surface is illuminated by laser,the field of diffusing reflective light can be described by Fresnel-Kirchhoff integration in the region of Fresnel.If the correlation,before and after the change of intensity field,is analysed by statistical method,three governing equations for variations of intensity field and speckle movement formulas can be obtained.In these equations,the surface motion,deformation and wavelength change are all considered to cause the speckle movement.
