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Attack-Resilient Distributed Cooperative Control of Virtually Coupled High-Speed Trains via Topology Reconfiguration
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作者 Shunyuan Xiao Xiaohua Ge Qing Wu 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第4期1066-1068,共3页
Dear Editor,This letter addresses the resilient distributed cooperative control problem of a virtually coupled train convoy under stochastic disturbances and cyber attacks.The main purpose is to achieve distributed co... Dear Editor,This letter addresses the resilient distributed cooperative control problem of a virtually coupled train convoy under stochastic disturbances and cyber attacks.The main purpose is to achieve distributed coordination of virtually coupled high-speed trains with the prescribed inter-train distance and same cruise velocity. 展开更多
关键词 PRESCRIBED speed TRAINS
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Effect of speed humps on instantaneous traffic emissions in a microscopic model with limited deceleration capacity
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作者 胡宇晨 李启朗 +2 位作者 刘军 王君霞 汪秉宏 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第6期413-420,共8页
As a common transportation facility, speed humps can control the speed of vehicles on special road sections to reduce traffic risks. At the same time, they also cause instantaneous traffic emissions. Based on the clas... As a common transportation facility, speed humps can control the speed of vehicles on special road sections to reduce traffic risks. At the same time, they also cause instantaneous traffic emissions. Based on the classic instantaneous traffic emission model and the limited deceleration capacity microscopic traffic flow model with slow-to-start rules, this paper has investigated the impact of speed humps on traffic flow and the instantaneous emissions of vehicle pollutants in a single lane situation. The numerical simulation results have shown that speed humps have significant effects on traffic flow and traffic emissions. In a free-flow region, the increase of speed humps leads to the continuous rise of CO_(2), NO_(X) and PM emissions. Within some density ranges, one finds that these pollutant emissions can evolve into some higher values under some random seeds. Under other random seeds, they can evolve into some lower values. In a wide moving jam region, the emission values of these pollutants sometimes appear as continuous or intermittent phenomenon. Compared to the refined Na Sch model, the present model has lower instantaneous emissions such as CO_(2), NO_(X) and PM and higher volatile organic components(VOC) emissions. Compared to the limited deceleration capacity model without slow-to-start rules, the present model also has lower instantaneous emissions such as CO_(2), NO_(X) and PM and higher VOC emissions in a wide moving jam region. These results can also be confirmed or explained by the statistical values of vehicle velocity and acceleration. 展开更多
关键词 traffic emissions speed humps slow-to-start rules deceleration capacity
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Influence of span-to-depth ratio on dynamic response of vehicle-turnoutbridge system in high-speed railway
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作者 Chuanqing Dai Tao Xin +3 位作者 Shenlu Qiao Yanan Zhang Pengsong Wang Mahantesh M.Nadakatti 《High-Speed Railway》 2024年第1期30-41,共12页
For high-speed railways,the smoothness of the railway line significantly affects the operational speed of trains.When the train passes through the turnout on a long-span bridge,the wheel-rail impacts caused by the tur... For high-speed railways,the smoothness of the railway line significantly affects the operational speed of trains.When the train passes through the turnout on a long-span bridge,the wheel-rail impacts caused by the turnout structure irregularities,and the instability arising from the bridge's flexural deformation lead to a strong coupling effect in the vehicle-turnout-bridge system.This significantly affects both ride comfort and operational safety.For addressing this issue,the present study considered a long-span continuous rigid-frame bridge as an example and established a train-turnout-bridge coupled dynamic model of high-speed railway.Utilizing a selfdeveloped dynamic simulation program,the study analysed the dynamic response characteristics when the train passes through the turnouts on the bridge.It also investigated the influence of different span-to-depth ratios of the bridge on the vehicle dynamic response when the train passes through the main line and branch line of turnouts and then proposed a span-to-depth ratio limit value for a long-span continuous rigid-frame bridge.The research findings suggest that the changes in the span-to-depth ratio have a relatively minor impact on the train’s operational performance but significantly affect the dynamic characteristics of the bridge structure.Based on the findings and a comprehensive assessment of safety indicators,it is advisable to establish a span-to-depth ratio limit of 1/4500 for a long-span continuous rigid-frame bridge. 展开更多
关键词 Turnout on bridge Span-to-depth ratio Dynamic response Vehicle-turnout-bridge system High-speed railway
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Research on Instantaneous Angular Speed Signal Separation Method for Planetary Gear Fault Diagnosis
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作者 Xinkai Song Yibao Zhang Shuo Zhang 《Modern Mechanical Engineering》 2024年第2期39-50,共12页
Planetary gear train is a critical transmission component in large equipment such as helicopters and wind turbines. Conducting damage perception of planetary gear trains is of great significance for the safe operation... Planetary gear train is a critical transmission component in large equipment such as helicopters and wind turbines. Conducting damage perception of planetary gear trains is of great significance for the safe operation of equipment. Existing methods for damage perception of planetary gear trains mainly rely on linear vibration analysis. However, these methods based on linear vibration signal analysis face challenges such as rich vibration sources, complex signal coupling and modulation mechanisms, significant influence of transmission paths, and difficulties in separating damage information. This paper proposes a method for separating instantaneous angular speed (IAS) signals for planetary gear fault diagnosis. Firstly, this method obtains encoder pulse signals through a built-in encoder. Based on this, it calculates the IAS signals using the Hilbert transform, and obtains the time-domain synchronous average signal of the IAS of the planetary gear through time-domain synchronous averaging technology, thus realizing the fault diagnosis of the planetary gear train. Experimental results validate the effectiveness of the calculated IAS signals, demonstrating that the time-domain synchronous averaging technology can highlight impact characteristics, effectively separate and extract fault impacts, greatly reduce the testing cost of experiments, and provide an effective tool for the fault diagnosis of planetary gear trains. 展开更多
关键词 Planetary Gear Train Encoder Signal Instantaneous Angular speed Signal Time-Domain Synchronous Averaging Fault Diagnosis
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基于改进Ratio统计量的重尾AR(p)时间序列均值变点检验
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作者 张思 刘叶 金浩 《统计与决策》 CSSCI 北大核心 2024年第2期52-57,共6页
文章提出两个改进的Ratio统计量来研究重尾AR(p)时间序列均值变点检验问题,在原假设下推导了统计量的渐近分布,且在备择假设下证明了其一致性。由于重尾指数未知且难以估计,因此结合Wild Bootstrap重抽样方法来确定渐近分布的临界值;在... 文章提出两个改进的Ratio统计量来研究重尾AR(p)时间序列均值变点检验问题,在原假设下推导了统计量的渐近分布,且在备择假设下证明了其一致性。由于重尾指数未知且难以估计,因此结合Wild Bootstrap重抽样方法来确定渐近分布的临界值;在均值变点存在的情形下,给出了变点位置的一致估计量。数值模拟结果表明:统计量的临界值均不受重尾指数和自回归系数的影响,其经验水平和经验势均取得满意的效果;尤其在原假设下,积分型Ratio统计量的经验水平表现出更好的稳健性,而在备择假设下,最值型Ratio统计量则具备更好的显著性。最后,基于一组股票数据,从实际应用角度进一步阐明所提方法的有效性和可行性。 展开更多
关键词 重尾序列 ratio统计量 均值变点 Wild Bootstrap
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Yields,growth and water use under chemical topping in relations to row configuration and plant density in drip-irrigated cotton 被引量:1
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作者 Wang Xuejiao Hu Yanping +10 位作者 Ji Chunrong Chen Yongfan Sun Shuai Zhang Zeshan Zhang Yutong Wang Sen Yang Mingfeng Ji Fen Guo Yanyun Li Jie Zhang Lizhen 《Journal of Cotton Research》 CAS 2024年第2期123-136,共14页
Background Water deficit is an important problem in agricultural production in arid regions.With the advent of wholly mechanized technology for cotton planting in Xinjiang,it is important to determine which planting m... Background Water deficit is an important problem in agricultural production in arid regions.With the advent of wholly mechanized technology for cotton planting in Xinjiang,it is important to determine which planting mode could achieve high yield,fiber quality and water use efficiency(WUE).This study aimed to explore if chemical topping affected cotton yield,quality and water use in relation to row configuration and plant densities.Results Experiments were carried out in Xinjiang China,in 2020 and 2021 with two topping method,manual topping and chemical topping,two plant densities,low and high,and two row configurations,i.e.,76 cm equal rows and 10+66 cm narrow-wide rows,which were commonly applied in matching harvest machine.Chemical topping increased seed cotton yield,but did not affect cotton fiber quality comparing to traditional manual topping.Under equal row spacing,the WUE in higher density was 62.4%higher than in the lower one.However,under narrow-wide row spacing,the WUE in lower density was 53.3%higher than in higher one(farmers’practice).For machine-harvest cotton in Xinjiang,the optimal row configuration and plant density for chemical topping was narrow-wide rows with 15 plants m-2 or equal rows with 18 plants m-2.Conclusion The plant density recommended in narrow-wide rows was less than farmers’practice and the density in equal rows was moderate with local practice.Our results provide new knowledge on optimizing agronomic managements of machine-harvested cotton for both high yield and water efficient. 展开更多
关键词 Yield components Fiber quality TRANSPIratioN Water use efficiency Heat ratio method(HRM)
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Combining lymph node ratio to develop prognostic models for postoperative gastric neuroendocrine neoplasm patients 被引量:1
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作者 Wen Liu Hong-Yu Wu +4 位作者 Jia-Xi Lin Shu-Ting Qu Yi-Jie Gu Jin-Zhou Zhu Chun-Fang Xu 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第8期3507-3520,共14页
BACKGROUND Lymph node ratio(LNR)was demonstrated to play a crucial role in the prognosis of many tumors.However,research concerning the prognostic value of LNR in postoperative gastric neuroendocrine neoplasm(NEN)pati... BACKGROUND Lymph node ratio(LNR)was demonstrated to play a crucial role in the prognosis of many tumors.However,research concerning the prognostic value of LNR in postoperative gastric neuroendocrine neoplasm(NEN)patients was limited.AIM To explore the prognostic value of LNR in postoperative gastric NEN patients and to combine LNR to develop prognostic models.METHODS A total of 286 patients from the Surveillance,Epidemiology,and End Results database were divided into the training set and validation set at a ratio of 8:2.92 patients from the First Affiliated Hospital of Soochow University in China were designated as a test set.Cox regression analysis was used to explore the relationship between LNR and disease-specific survival(DSS)of gastric NEN patients.Random survival forest(RSF)algorithm and Cox proportional hazards(CoxPH)analysis were applied to develop models to predict DSS respectively,and compared with the 8th edition American Joint Committee on Cancer(AJCC)tumornode-metastasis(TNM)staging.RESULTS Multivariate analyses indicated that LNR was an independent prognostic factor for postoperative gastric NEN patients and a higher LNR was accompanied by a higher risk of death.The RSF model exhibited the best performance in predicting DSS,with the C-index in the test set being 0.769[95%confidence interval(CI):0.691-0.846]outperforming the CoxPH model(0.744,95%CI:0.665-0.822)and the 8th edition AJCC TNM staging(0.723,95%CI:0.613-0.833).The calibration curves and decision curve analysis(DCA)demonstrated the RSF model had good calibration and clinical benefits.Furthermore,the RSF model could perform risk stratification and individual prognosis prediction effectively.CONCLUSION A higher LNR indicated a lower DSS in postoperative gastric NEN patients.The RSF model outperformed the CoxPH model and the 8th edition AJCC TNM staging in the test set,showing potential in clinical practice. 展开更多
关键词 Gastric neuroendocrine neoplasm Lymph node ratio Disease-specific survival Random survival forest Predictive model
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Study of Star-Delta Soft Switch to Extend AC Motor High Speed Operation Region
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作者 Yixuan Shuai Dong Jiang +3 位作者 Zhuo Chen Zicheng Liu Haijing Sun Peng Li 《CES Transactions on Electrical Machines and Systems》 CSCD 2023年第3期248-255,共8页
In traction application,speed range of motor is an important index for motor drives.In AC motor control,the maximum speed of the motor is limited by the output voltage capability of the traditional three-phase inverte... In traction application,speed range of motor is an important index for motor drives.In AC motor control,the maximum speed of the motor is limited by the output voltage capability of the traditional three-phase inverter with star connenction of windings.Switching the star connection to delta connection in high-speed range can extend the speed range.In order to extend the speed operation region,star-delta switch proposed by many literatures relies on mechanical relay,which needs a dead zone of tens of milliseconds and seriously affects torque output.Besides,the traditional method will cause current overshoot during the switch transient process,decreasing the device security and reliability.Aiming at the defects existing in the star-delta hard switching,this paper proposes a star-delta soft switching method.Without adding extra power electronics devices,DC-bus capacitor is used to provide the path of zero axis current in the transient process,which helps to achieve the smooth torque output and zero current switch in the transient.Experiments have been done to validate the performance of the proposed method.The switching transient from star to delta connection in the motor drive can be much more stable than hard switching method. 展开更多
关键词 speed range Soft switch 0-axis current Zero current switch
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Switching Frequency Improvement of a High Speed on/off Valve Based on Pre-excitation Control Algorithm
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作者 Qi Zhong Xiaotian Li +4 位作者 Yongxin Mao Enguang Xu Tiwei Jia Yanbiao Li Huayong Yang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第4期94-106,共13页
The high-speed on/off valve(HSV)serves as the fundamental component responsible for generating discrete fluids within digital hydraulic systems.As the switching frequency of the HSV increases,the properties of the gen... The high-speed on/off valve(HSV)serves as the fundamental component responsible for generating discrete fluids within digital hydraulic systems.As the switching frequency of the HSV increases,the properties of the generated discrete fluid approach those of continuous fluids.Therefore,a higher frequency response characteristic of HSV is the key to ensure the control accuracy of digital hydraulic systems.However,the current research mainly focuses on its dynamic performance,but neglect its FRC.This paper presents a theoretical analysis demonstrating that the FRC of the HSV can be enhanced by minimizing its switching time.The maximum switching frequency(MSF)is mainly determined by opening dynamic performance when HSV operates with low switching duty ratio(SDR),whereas the closing dynamic performance limits the MSF when HSV operates with high SDR.Building upon these findings,the pre-excitation control algorithm(PECA)is proposed to reduce the switching time of the HSV,and consequently enhance its FRC.Experimental results demonstrate that PECA shortens the opening delay time of HSV by 1.12 ms,the closing delay time by 2.54 ms,and the closing moving time by 0.47 ms in comparison to the existing advanced control algorithms.As a result,a larger MSF of 417 Hz and a wider controllable SDR range from 20%to 70%were achieved at a switching frequency of 250 Hz.Thus,the proposed PFCA in this paper has been verified as an effective and promising approach for enhancing the control performance of digital hydraulic systems. 展开更多
关键词 High speed on/off valve Switching frequency Pre-excitation Dynamic performance Switching duty ratio
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A gated recurrent unit model to predict Poisson’s ratio using deep learning 被引量:1
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作者 Fahd Saeed Alakbari Mysara Eissa Mohyaldinn +4 位作者 Mohammed Abdalla Ayoub Ibnelwaleed A.Hussein Ali Samer Muhsan Syahrir Ridha Abdullah Abduljabbar Salih 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第1期123-135,共13页
Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to spe... Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to specific data ranges with an average absolute percentage relative error(AAPRE)of more than 10%.The published gated recurrent unit(GRU)models do not consider trend analysis to show physical behaviors.In this study,we aim to develop a GRU model using trend analysis and three inputs for predicting n s based on a broad range of data,n s(value of 0.1627-0.4492),bulk formation density(RHOB)(0.315-2.994 g/mL),compressional time(DTc)(44.43-186.9 μs/ft),and shear time(DTs)(72.9-341.2μ s/ft).The GRU model was evaluated using different approaches,including statistical error an-alyses.The GRU model showed the proper trends,and the model data ranges were wider than previous ones.The GRU model has the largest correlation coefficient(R)of 0.967 and the lowest AAPRE,average percent relative error(APRE),root mean square error(RMSE),and standard deviation(SD)of 3.228%,1.054%,4.389,and 0.013,respectively,compared to other models.The GRU model has a high accuracy for the different datasets:training,validation,testing,and the whole datasets with R and AAPRE values were 0.981 and 2.601%,0.966 and 3.274%,0.967 and 3.228%,and 0.977 and 2.861%,respectively.The group error analyses of all inputs show that the GRU model has less than 5% AAPRE for all input ranges,which is superior to other models that have different AAPRE values of more than 10% at various ranges of inputs. 展开更多
关键词 Static Poisson’s ratio Deep learning Gated recurrent unit(GRU) Sand control Trend analysis Geomechanical properties
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Serum cystatin C,monocyte/high-density lipoprotein-C ratio,and uric acid for the diagnosis of coronary heart disease and heart failure 被引量:1
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作者 Ming Li Da-Hao Yuan +2 位作者 Zhi Yang Teng-Xiang Luw Xiao-Biao Zou 《World Journal of Clinical Cases》 SCIE 2024年第18期3461-3467,共7页
BACKGROUND Coronary heart disease(CHD)and heart failure(HF)are the major causes of morbidity and mortality worldwide.Early and accurate diagnoses of CHD and HF are essential for optimal management and prognosis.Howeve... BACKGROUND Coronary heart disease(CHD)and heart failure(HF)are the major causes of morbidity and mortality worldwide.Early and accurate diagnoses of CHD and HF are essential for optimal management and prognosis.However,conventional diagnostic methods such as electrocardiography,echocardiography,and cardiac biomarkers have certain limitations,such as low sensitivity,specificity,availability,and cost-effectiveness.Therefore,there is a need for simple,noninvasive,and reliable biomarkers to diagnose CHD and HF.AIM To investigate serum cystatin C(Cys-C),monocyte/high-density lipoprotein cholesterol ratio(MHR),and uric acid(UA)diagnostic values for CHD and HF.METHODS We enrolled 80 patients with suspected CHD or HF who were admitted to our hospital between July 2022 and July 2023.The patients were divided into CHD(n=20),HF(n=20),CHD+HF(n=20),and control groups(n=20).The serum levels of Cys-C,MHR,and UA were measured using immunonephelometry and an enzymatic method,respectively,and the diagnostic values for CHD and HF were evaluated using receiver operating characteristic(ROC)curve analysis.RESULTS Serum levels of Cys-C,MHR,and UA were significantly higher in the CHD,HF,and CHD+HF groups than those in the control group.The serum levels of Cys-C,MHR,and UA were significantly higher in the CHD+HF group than those in the CHD or HF group.The ROC curve analysis showed that serum Cys-C,MHR,and UA had good diagnostic performance for CHD and HF,with areas under the curve ranging from 0.78 to 0.93.The optimal cutoff values of serum Cys-C,MHR,and UA for diagnosing CHD,HF,and CHD+HF were 1.2 mg/L,0.9×10^(9),and 389μmol/L;1.4 mg/L,1.0×10^(9),and 449μmol/L;and 1.6 mg/L,1.1×10^(9),and 508μmol/L,respectively.CONCLUSION Serum Cys-C,MHR,and UA are useful biomarkers for diagnosing CHD and HF,and CHD+HF.These can provide information for decision-making and risk stratification in patients with CHD and HF. 展开更多
关键词 Serum cystatin C Monocyte/high-density lipoprotein-C ratio Uric acid Coronary heart disease Heart failure Risk stratification
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Systemic immune-inflammation index,neutrophilto-lymphocyte ratio,and platelet-to-lymphocyte ratio in patients with type 2 diabetes at different stages of diabetic retinopathy
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作者 Ying Gao Rong-Xin Lu +6 位作者 Yun Tang Xin-Yi Yang Hu Meng Chang-Lin Zhao Yi-Lu Chen Feng Yan Qian Cao 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第5期877-882,共6页
AIM:To investigate systemic immune-inflammation index(SII),neutrophil-to-lymphocyte ratio(NLR),and plateletto-lymphocyte ratio(PLR)levels in patients with type 2 diabetes at different stages of diabetic retinopathy(DR... AIM:To investigate systemic immune-inflammation index(SII),neutrophil-to-lymphocyte ratio(NLR),and plateletto-lymphocyte ratio(PLR)levels in patients with type 2 diabetes at different stages of diabetic retinopathy(DR).METHODS:This retrospective study included 141 patients with type 2 diabetes mellitus(DM):45 without diabetic retinopathy(NDR),47 with non-proliferative diabetic retinopathy(NPDR),and 49 with proliferative diabetic retinopathy(PDR).Complete blood counts were obtained,and NLR,PLR,and SII were calculated.The study analysed the ability of inflammatory markers to predict DR using receiver operating characteristic(ROC)curves.The relationships between DR stages and SII,PLR,and NLP were assessed using multivariate logistic regression.RESULTS:The average NLR,PLR,and SII were higher in the PDR group than in the NPDR group(P=0.011,0.043,0.009,respectively);higher in the NPDR group than in the NDR group(P<0.001 for all);and higher in the PDR group than in the NDR group(P<0.001 for all).In the ROC curve analysis,the NLR,PLR,and SII were significant predictors of DR(P<0.001 for all).The highest area under the curve(AUC)was for the PLR(0.929 for PLR,0.925 for SII,and 0.821 for NLR).Multivariate regression analysis indicated that NLR,PLR,and SII were statistically significantly positive and independent predictors for the DR stages in patients with DM[odds ratio(OR)=1.122,95%confidence interval(CI):0.200–2.043,P<0.05;OR=0.038,95%CI:0.018–0.058,P<0.05;OR=0.007,95%CI:0.001–0.01,P<0.05,respectively).CONCLUSION:The NLR,PLR,and SII may be used as predictors of DR. 展开更多
关键词 diabetic retinopathy neutrophil-tolymphocyte ratio platelet-to-lymphocyte ratio systemic immune-inflammation index
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Predictive Ability of Hypertriglyceridemic Waist,Hypertriglyceridemic Waist-to-Height Ratio,and Waist-to-Hip Ratio for Cardiometabolic Risk Factors Clustering Screening among Chinese Children and Adolescents
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作者 XIAO Tian Li YUAN Shu Qian +6 位作者 GAO Jing Yu Julien SBaker YANG Yi De WANG Xi Jie ZHENG Chan Juan DONG Yan Hui ZOU Zhi Yong 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2024年第3期233-241,共9页
Objective Hypertriglyceridemic waist(HW),hypertriglyceridemic waist-to-height ratio(HWHtR),and waist-to-hip ratio(WHR)have been shown to be indicators of cardiometabolic risk factors.However,it is not clear which indi... Objective Hypertriglyceridemic waist(HW),hypertriglyceridemic waist-to-height ratio(HWHtR),and waist-to-hip ratio(WHR)have been shown to be indicators of cardiometabolic risk factors.However,it is not clear which indicator is more suitable for children and adolescents.We aimed to investigate the relationship between HW,HWHtR,WHR,and cardiovascular risk factors clustering to determine the best screening tools for cardiometabolic risk in children and adolescents.Methods This was a national cross-sectional study.Anthropometric and biochemical variables were assessed in approximately 70,000 participants aged 6–18 years from seven provinces in China.Demographics,physical activity,dietary intake,and family history of chronic diseases were obtained through questionnaires.ANOVA,χ2 and logistic regression analysis was conducted.Results A significant sex difference was observed for HWHtR and WHR,but not for HW phenotype.The risk of cardiometabolic health risk factor clustering with HW phenotype or the HWHtR phenotype was significantly higher than that with the non-HW or non-HWHtR phenotypes among children and adolescents(HW:OR=12.22,95%CI:9.54-15.67;HWHtR:OR=9.70,95%CI:6.93-13.58).Compared with the HW and HWHtR phenotypes,the association between risk of cardiometabolic health risk factors(CHRF)clustering and high WHR was much weaker and not significant(WHR:OR=1.14,95%CI:0.97-1.34).Conclusion Compared with HWHtR and WHR,the HW phenotype is a more convenient indicator with higher applicability to screen children and adolescents for cardiovascular risk factors. 展开更多
关键词 Hypertriglyceridemic waist Waist-to-hip ratio Children and adolescents China Hypertriglyceridemic waist-to-height ratio Cardiovascular risk factors
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Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio:Markers predicting immune-checkpoint inhibitor efficacy and immune-related adverse events
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作者 Qiu-Yu Jiang Ru-Yi Xue 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第3期577-582,共6页
We conducted a comprehensive review of existing prediction models pertaining to the efficacy of immune-checkpoint inhibitor(ICI)and the occurrence of immune-related adverse events(irAEs).The predictive potential of ne... We conducted a comprehensive review of existing prediction models pertaining to the efficacy of immune-checkpoint inhibitor(ICI)and the occurrence of immune-related adverse events(irAEs).The predictive potential of neutrophil-to-lymphocyte ratio(NLR)and platelet-to-lymphocyte ratio(PLR)in determining ICI effectiveness has been extensively investigated,while limited research has been conducted on predicting irAEs.Furthermore,the combined model incor-porating NLR and PLR,either with each other or in conjunction with additional markers such as carcinoembryonic antigen,exhibits superior predictive capabilities compared to individual markers alone.NLR and PLR are promising markers for clinical applications.Forthcoming models ought to incorporate established efficacious models and newly identified ones,thereby constituting a multifactor composite model.Furthermore,efforts should be made to explore effective clinical application approaches that enhance the predictive accuracy and efficiency. 展开更多
关键词 Neutrophil-to-lymphocyte ratio Platelet-to-lymphocyte ratio Immunecheckpoint inhibitor Immune-related adverse event
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Speed limit effect during lane change in a two-lane lattice model under V2X environment
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作者 金灿 彭光含 聂方彦 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期718-722,共5页
Speed limit measures are ubiquitous due to the complexity of the road environment,which can be supplied with the help of vehicle to everything(V2X)communication technology.Therefore,the influence of speed limit on tra... Speed limit measures are ubiquitous due to the complexity of the road environment,which can be supplied with the help of vehicle to everything(V2X)communication technology.Therefore,the influence of speed limit on traffic system will be investigated to construct a two-lane lattice model accounting for the speed limit effect during the lane change process under V2X environment.Accordingly,the stability condition and the mKdV equation are closely associated with the speed limit effect through theory analysis.Moreover,the evolution of density and hysteresis loop is simulated to demonstrate the positive role of the speed limit effect on traffic stability in the cases of strong reaction intensity and high limited speed. 展开更多
关键词 traffic flow lattice model speed limit
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Clinical study of neutrophil-to-lymphocyte ratio and platelet-tolymphocyte ratio in hypertriglyceridemia-induced acute pancreatitis and acute biliary pancreatitis with persistent organ failure
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作者 Mu-Sen Xu Jia-Le Xu +5 位作者 Xin Gao Shao-Jian Mo Jia-Yu Xing Jia-Hang Liu Yan-Zhang Tian Xi-Feng Fu 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第6期1647-1659,共13页
BACKGROUND The neutrophil-to-lymphocyte ratio(NLR)and platelet-to-lymphocyte ratio(PLR)are novel inflammatory indicators that can be used to predict the severity and prognosis of various diseases.We categorize acute p... BACKGROUND The neutrophil-to-lymphocyte ratio(NLR)and platelet-to-lymphocyte ratio(PLR)are novel inflammatory indicators that can be used to predict the severity and prognosis of various diseases.We categorize acute pancreatitis by etiology into acute biliary pancreatitis(ABP)and hypertriglyceridemia-induced acute pancreatitis(HTGP).AIM To investigate the clinical significance of NLR and PLR in assessing persistent organ failure(POF)in HTGP and ABP.METHODS A total of 1450 patients diagnosed with acute pancreatitis(AP)for the first time at Shanxi Bethune Hospital between January 2012 and January 2023 were enrolled.The patients were categorized into two groups according to the etiology of AP:ABP in 530 patients and HTGP in 241 patients.We collected and compared the clinical data of the patients,including NLR,PLR,and AP prognostic scoring systems,within 48 h of hospital admission.RESULTS The NLR(9.1 vs 6.9,P<0.001)and PLR(203.1 vs 160.5,P<0.001)were significantly higher in the ABP group than in the HTGP group.In the HTGP group,both NLR and PLR were significantly increased in patients with severe AP and those with a SOFA score≥3.Likewise,in the ABP group,NLR and PLR were significantly elevated in patients with severe AP,modified computed tomography severity index score≥4,Japanese Severity Score≥3,and modified Marshall score≥2.Moreover,NLR and PLR showed predictive value for the development of POF in both the ABP and HTGP groups.CONCLUSION NLR and PLR vary between ABP and HTGP,are strongly associated with AP prognostic scoring systems,and have predictive potential for the occurrence of POF in both ABP and HTGP. 展开更多
关键词 Acute pancreatitis GALLSTONE HYPERTRIGLYCERIDEMIA Neutrophil-to-lymphocyte ratio Platelet-to-lymphocyte ratio Persistent organ failure
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Complementary-Label Adversarial Domain Adaptation Fault Diagnosis Network under Time-Varying Rotational Speed and Weakly-Supervised Conditions
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作者 Siyuan Liu Jinying Huang +2 位作者 Jiancheng Ma Licheng Jing Yuxuan Wang 《Computers, Materials & Continua》 SCIE EI 2024年第4期761-777,共17页
Recent research in cross-domain intelligence fault diagnosis of machinery still has some problems,such as relatively ideal speed conditions and sample conditions.In engineering practice,the rotational speed of the mac... Recent research in cross-domain intelligence fault diagnosis of machinery still has some problems,such as relatively ideal speed conditions and sample conditions.In engineering practice,the rotational speed of the machine is often transient and time-varying,which makes the sample annotation increasingly expensive.Meanwhile,the number of samples collected from different health states is often unbalanced.To deal with the above challenges,a complementary-label(CL)adversarial domain adaptation fault diagnosis network(CLADAN)is proposed under time-varying rotational speed and weakly-supervised conditions.In the weakly supervised learning condition,machine prior information is used for sample annotation via cost-friendly complementary label learning.A diagnosticmodel learning strategywith discretized category probabilities is designed to avoidmulti-peak distribution of prediction results.In adversarial training process,we developed virtual adversarial regularization(VAR)strategy,which further enhances the robustness of the model by adding adversarial perturbations in the target domain.Comparative experiments on two case studies validated the superior performance of the proposed method. 展开更多
关键词 Time-varying rotational speed weakly-supervised fault diagnosis domain adaptation
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Energy harvesting and speed sensing with a hybrid rotary generator for self-powered wireless monitoring
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作者 Zhixia Wang Hongyun Qiu +4 位作者 Xuanbo Jiao Wei Wang Qichang Zhang Ruilan Tian Dongxing Cao 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2024年第9期116-130,共15页
Real-time onboard health monitoring systems are critical for the railway industry to maintain high service quality and operational safety.However,the issue with power supplies for monitoring sensors persists,especiall... Real-time onboard health monitoring systems are critical for the railway industry to maintain high service quality and operational safety.However,the issue with power supplies for monitoring sensors persists,especially for freight trains that lack onboard power.Here,we propose a hybrid piezoelectric-triboelectric rotary generator(HPT-RG)for energy harvesting and vehicle speed sensing.The HPT-RG incorporates a rotational self-adaptive technique that softens the equivalent stiffness,enabling the piezoelectric non-resonant beam to surpass resonance limitations in a low-frequency region.The experiments demonstrate the feasibility of using the HPT-RG as an energy harvesting module to collect the rotational energy of the freight rail transport and power the wireless temperature sensors.To allow multiple monitoring in confined spaces on trains,a triboelectric sensing module is added to the HPT-RG to sense the operation speed and mileage of vehicles.Furthermore,the generator exhibits favorable mechanical durability under more than 600 h of official testing on the train bogie axle.The proposed HPT-RG is essential for creating a truly self-powered,maintenance-free,and zero-carbon onboard wireless monitoring system on freight railways. 展开更多
关键词 Energy harvesting speed sensing Rotational self-adaptive technique LOW-FREQUENCY Self-powered wireless monitoring
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Experimental Study of Local Scour Around Four Piles Under Different Attack Angles and Gap Ratios
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作者 LIU Ming-ming TANG Guo-qiang +1 位作者 JIN Xin GENG Shao-yang 《China Ocean Engineering》 SCIE EI CSCD 2024年第4期612-624,共13页
In an effort to investigate and quantify the patterns of local scour,researchers embarked on an in-depth study using a systematic experimental approach.The research focused on the effects of local scour around a set o... In an effort to investigate and quantify the patterns of local scour,researchers embarked on an in-depth study using a systematic experimental approach.The research focused on the effects of local scour around a set of four piles,each subjected to different hydromechanical conditions.In particular,this study aimed to determine how different attack angles—the angles at which the water flow impinges on the piles,and gap ratios—the ratios of the spacing between the piles to their diameters,influence the extent and nature of scour.A comprehensive series of 35 carefully designed experiments were orchestrated,each designed to dissect the nuances in how the gap ratio and attack angle might contribute to changes in the local scour observed at the base of pile groups.During these experimental trials,a wealth of local scour data were collected to support the analysis.These data included precise topographic profiles of the sediment bed around the pile groups,as well as detailed scour time histories showing the evolution of scour at strategic feature points throughout the test procedure.The analysis of the experimental data provided interesting insights.The study revealed that the interplay between the gap ratio and the attack angle had a pronounced influence on the scouring dynamics of the pile groups.One of the key observations was that the initial phases of scour,particularly within the first hour of water flow exposure,were characterized by a sharp increase in the scour depth occurring immediately in front of the piles.After this initial rapid development,the scour depth transitioned to a more gradual change rate.In contrast,the scour topography around the piles continuously evolved.This suggests that sediment displacement and the associated sculpting of the seabed around pile foundations are sustained and progressive processes,altering the underwater landscape over time.The results of this empirical investigation have significant implications for the design and construction of offshore multi-pile foundations,providing a critical reference for engineers and designers to estimate the expected scour depth around such structures,which is an integral part of decisions regarding foundation design,selection of structural materials,and implementation of scour protection measures. 展开更多
关键词 local scour PILES gap ratio attack angle
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Effect of length-width ratio of rounded rectangle aquaculture tank in dual-diagonal-inlet layout on hydrodynamics
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作者 Meng LI Xiaozhong REN +4 位作者 Shupeng DU Wei SUN Chenxu ZHAO Hangfei LIU Xianying SHI 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2024年第5期1695-1709,共15页
To adapt to the change of aquaculture workshop site,optimize the shape of aquaculture tanks and improve the utilization rate of breeding space,it is necessary to determine the appropriate length width ratio parameters... To adapt to the change of aquaculture workshop site,optimize the shape of aquaculture tanks and improve the utilization rate of breeding space,it is necessary to determine the appropriate length width ratio parameters of aquaculture tanks.In this paper,computational fluid dynamics(CFD)technology is adopted to study the flow field performance of aquaculture tanks with different L/B ratios(L:the length;B:the width,of aquaculture tank)and different jet direction conditions(lengthways jet and widthways jet).A three-dimensional numerical calculation model of turbulence in rounded rectangle aquaculture tanks in dual-diagonal-inlet layout was established.Jet directions are arranged lengthways and widthways,and the water flow velocity,resistance coefficient change,vorticity,etc.are analyzed under two working conditions.Results show that the flow field performance in aquaculture tank decreases with the increase of the L/B ratio.The flow field performed well when L/B was 1.0-1.3,sharply dropped at 1.4-1.6,and poor at 1.7-1.9.The results provided a theoretical basis for the design and optimization in flow field performance of the industrialized circulating aquaculture tanks. 展开更多
关键词 aquaculture tank length-width ratio computational fluid dynamic hydrodynamic
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