Current and future surgery strategies for spinal cord injuries

Spinal cord trauma is a prominent cause of mortality and morbidity. In developed countries a spinal cord injury(SCI) occurs every 16 min. SCI occurs due to tissue destruction, primarily by mechanical and secondarily ischemic. Primary damage occurs at the time of the injury. It cannot be improved. Following the primary injury, secondary harm mechanisms gradually result in neuronal death. One of the prominent causesof secondary harm is energy deficit, emerging from ischemia, whose main cause in the early stage, is impaired perfusion. Due to the advanced techniques in spinal surgery, SCI is still challenging for surgeons. Spinal cord doesn't have a self-repair property. The main damage occurs at the time of the injury primarily by mechanical factors that cannot be improved. Secondarily mechanisms take part in the following sections. Spinal compression and neurological deficit are two major factors used to decide on surgery. According to advanced imaging techniques the classifications systems for spinal injury has been changed in time. Aim of the surgery is to decompress the spinal channel and to restore the spinal alinement and mobilize the patient as soon as possible. Use of neuroprotective agents as well as methods to achieve cell regeneration in addition to surgery would contribute to the solution.

Survival and clinical outcomes in patients with metastatic epidural spinal cord compression after spinal surgery:a prospective,multicenter,observational cohort study

Background:High quality studies have been challenging to undertake in patients with metastatic epidural spinal cord compression.Nonetheless,in the article "Survival and Clinical Outcomes in Surgically Treated Patients With Metastatic Epidural Spinal Cord Compression:Results of the Prospective Multicenter AOSpine Study" recently published in the Journal of Clinical Oncology,our team provided convincing evidence that spinal surgery improves overall quality of life in patients with this potentially devastating complication of cancer.Considering that metastatic spinal lesions treated with surgery have the highest mean cost among all oncological musculo-skeletal issues,it is essential to provide high quality data to optimize the therapeutic approaches and cost-effective use of health care resources.Main body:Although the AOSpine Study provided high quality prospective data,it was primarily limited by the lack of non-operative controls and the relatively small sample size.Given the dearth of medical equipoise and the fundamental difference between patients deemed to be adequate surgical candidates and those who are not amenable to operative intervention,conducting a randomized controlled trial in this patient population was not felt to be ethically or medically feasible.Consequently,the optimal option to overcome limitations of both the lack of controls and the relatively small sample size is through collection of large prospective datasets through rigorously developed and maintained registries.Conclusions:With the alarming increase in the incidence of cancer in China and China's parallel growing cancer control efforts,China would offer a fantastic platform to set up a national metastatic spinal lesion registry.Such registry would not only enhance metastatic epidural spinal cord compression translational research but also optimize patient care.

Effectiveness and postoperative rehabilitation of one-stage combined anterior-posterior surgery for severe thoracolumbar fractures with spinal cord injury

BACKGROUND Thoracolumbar fractures are generally combined with spinal cord injury to varying degrees,which may cause deterioration of the patients’condition and increase the difficulty of clinical treatment.At present,anterior or combined anterior-posterior surgery is preferred for severe thoracolumbar fractures.AIM To investigate the effectiveness and postoperative rehabilitation of one-stage combined anterior-posterior surgery for severe thoracolumbar fractures with spinal cord injury.METHODS One-hundred-and-twenty patients who received surgery for severe thoracolumbar fractures with spinal cord injury at our hospital from February 2018 to February 2020 were randomly enrolled.They were randomly divided into group 1(one-stage combined anterior-posterior surgery,n=60)and group 2(onestage anterior-approach surgery,n=60).Treatment efficacy was compared between the two groups.RESULTS Blood loss was greater and the operation time was longer in group 1 than in group 2,and the differences were statistically significant(P<0.05).Incision length,intraoperative X-rays,and length of hospital stay were not significantly different between the two groups(P>0.05).Preoperative function of the affected vertebrae was not significantly different between the two groups(P>0.05).In each group,the patients showed significant improvement after surgery.The anterior vertebral height ratio and the posterior vertebral height ratio in group 1 after surgery were significantly higher than those in group 2.The Cobb angle after surgery was significantly lower in group 1 than in group 2(P<0.05).The canal-occupying ratio of the affected vertebrae was not significantly different between the two groups(P>0.05).Before surgery,there was no significant difference in the quality of life scores between the two groups(P>0.05).The above indicators were significantly improved after surgery compared with before surgery in each group.In addition,these indicators were markedly better in group 1 than in group 2 after surgery(P<0.05 for each).CONCLUSION One-stage combined anterior-posterior surgery effectively improves the function of the affected vertebrae and the life quality of patients with severe thoracolumbar fractures and spinal cord injury.This surgical approach is worthy of popularization in clinical use.

Evolution and Role of Intraoperative Neurophysiological Monitoring in Intramedullary Spinal Cord Surgery: A 2-Year Series from Saudi Arabia

Introduction: Despite recent advances in neuroimaging and microsurgical techniques, surgical resection of spinal cord tumours remains a challenge. However, the evolution with advances and refinement of neurophysiological equipment and methodologies, intra-operative neurophysiolo- gical monitoring (IONM) is now regarded as an essential adjunct to the surgical management of intramedullary spinal cord tumours. This study aims to report our preliminary experience with IONM and emphasise its effective role of achieving maximum tumour resection and minimising neurological injury. Methods: This is a retrospective study performed at our institution between July 2012 and August 2013. It included a cohort of 6 consecutive patients presented with intramedullary spinal cord tumours. Their mean age was 26 years (range, 4 months - 37 years), all were males, and the mean follow up was 11.6 months. Results: We combined the use of somatosensory evoked potentials (SSEPs) and motor evoked potentials (MEPs) in spinal cord surgery. SSEPs are monitored during the incision of the dorsal midline of the spinal cord and this was used in two of our patients and MEPs were used as an essential monitoring during the tumour resection. In addition, we used free-running electromyography (EMG) and muscle MEPs (mMEPs) during tumour resection. Four of our patients (two with ependymoma, one with ganglioglioma, and one with pilocytic astrocytoma) had complete tumour resection and two patients (pilocytic and diffuse astrocytoma) had IONM changes during surgery and had partial tumour resection. At 6-month follow up all our patients had made a good recovery with no new neurological sequelae. Conclusion: This small series and literature review is presented to add and improve the understanding of IONM in intramedullary spinal cord procedures and to reinforce the importance of IONM in optimising tumour resection and neurological outcome. Our series confirm that without D-wave monitoring, free-running EMG and MEP monitoring during tumour resection remain an important adjunct. We also draw attention to the fact that changes in the free-running EMG occur before any changes in the MEPs are noted.

Impact of surgery on the outcome after spinal cord injury – current concepts and an outlook into the future

Traumatic spinal cord injury（SCI）remains a devastating neurological disorder leading to severe consequences for the affected individual and their families.Further,socioeconomic implications should not be neglected as well.Although life expectancy after SCI increased tremendously,therapeutic treatment options remain limited.

Imaging and clinical properties of inflammatory demyelinating pseudotumor in the spinal cord

Inflammatory demyelinating pseudotumor usually occurs in the brain and rarely occurs in the spinal cord. On imaging, inflammatory demyelinating pseudotumor appears very similar to intramedullary tumors such as gliomas. It is often misdiagnosed as intramedullary tumor and surgically resected. In view of this, the clinical and magnetic resonance imaging manifestations and the pathological fea- tures of 36 cases of inflammatory demyelinating pseudotumer in the spinal cord were retrospec- tively analyzed and summarized. Most of these cases suffered from acute or subacute onset and exhibited a sensofimotor disorder. Among them, six cases were misdiagnosed as having intrame- dullary gliomas, and inflammatory demyelinating pseudotumor was only identified and pathologically confirmed after surgical resection. Lesions in the cervical and thoracic spinal cord were common. Magnetic resonance imaging revealed edema and space-occupying lesions to varying degrees at the cervical-thoracic junction, with a predominant feature of non-closed rosette-like reinforcement （open-loop sign）. Pathological examination showed perivascular cuffing of predominantly dense lymphocytes, and demyelination was observed in six of the misdiagnosed cases. These re- sults suggest that tumor-like inflammatory demyelinating disease in the spinal cord is a kind of special demyelinating disease that can be categorized as inflammatory pseudotumor. These solitary lesions are easily confused with intramedullary neoplasms. Patchy or non-closed reinforcement （open-ring sign） on magnetic resonance imaging is the predominant property of inflammatory de- myelinating pseudotumor, and inflammatory cell infiltration and demyelination are additional patho- logical properties.

Factors related to improved American Spinal Injury Association grade of acute traumatic spinal cord injury

BACKGROUND Acute traumatic spinal cord injury(ATSCI)usually results in disability,yet data on contemporary national trends of ATSCI incidence are limited.AIM To provide a systematic and basic theoretical basis for improving the treatment of acute spinal cord injury.METHODS Data from the Peking University Third Hospital Inpatient Sample databases were analyzed.A total of 304 patients with ATSCI were included from 2012 to 2017.The epidemiological data,treatment,complications and clinical outcomes of these patients were reviewed.RESULTS Of the 304 patients,257(84.5%)were male,and 75%of the patients were 55 years old or younger.135 patients had improved follow-up American Spinal Injury Association(ASIA)grades(44.4%).Only 14 patients with ASIA grade A improved.A statistically significant difference in prognosis between patients who underwent surgery within 72 h and those who underwent surgery after 72 h was observed(P<0.05).Surgery within 72 h resulted in better prognosis.The Steroid group and the Non-Steroid group showed a significant difference in outcome among patients with ASIA grades A and B(P<0.05).Patients with pneumonia had a poorer prognosis than patients without pneumonia(P<0.05).Surgery within 72 h resulted in better prognosis.CONCLUSION This study found that there was no significant difference in hospitalization time and prognosis between the Steroid group and the Non-Steroid group,but the patients with severe spinal cord injury(ASIA grades A and B)who underwent surgery combined with steroid therapy had a better prognosis than those who underwent surgery alone.The disastrous consequences of ATSCI and lack of consensus on the management strategy are obvious.Further improvements in treatment planns are needed in order to obtain more reliable functional outcomes.

Evidence-based treatment for acute spinal cord injury

OBJECTIVE： To formulate an evidence-based treatment for one patient with acute spinal cord injury and summarize evidence for evaluating acute spinal cord injury treatment. METHODS： Studies related to the treatment for acute spinal cord injury were identified via a search of National Guideline Clearinghouse （NGC, 2000 11）, the Cochrane Library （Issue 1,2011）, TRIP Database （2000 11）, and PubMed （1966-2011）. Treatment strategies were formulated according to three basic principles： best evidence, doctor＇s professional experience, and wishes of the patient. RESULTS： A total of 34 articles were selected, including 1 NGC guideline, 22 systematic reviews, and 11 randomized controlled trials. Based on our review, we arrived at the following recommendations： no clinical evidence exists definitively to recommend the use of any of neuroprotective pharmaceuticals; surgery should be undertaken early; mechanical compression devices and low-molecular weight heparin should be employed to prevent thrombosis; respiratory muscle training is beneficial for pulmonary function and quality of life; and functional electrical stimulation and acupuncture can promote functional recovery. The patient accordingly underwent surgery 6 hours after trauma without receiving any neuroprotective pharmaceuticals; low-molecular weight heparin and intermittent pneumatic compression were applied to prevent thrombosis. He also underwent respiratory muscle training daily for 8 weeks and received functional electrical stimulation for 15 minutes and acupuncture for 30 minutes every day. After follow-up for 3 months, the above therapeutic regimen was confirmed efficacious for acute spinal cord injury. CONCLUSION： Evidence-based medicine provides an individualized treatment protocol for acute spinal cord injury, which can significantly improve the therapeutic effect and prognosis.

Surgical reconstruction of spinal cord circuit provides functional return in humans

This mini review describes the current surgical strategy for restoring function after traumatic spinal nerve root avulsion in brachial or lumbosacral plexus injury in man. As this lesion is a spinal cord or central nervous injury functional return depends on spinal cord nerve cell growth within the central nervous system. Basic science, clinical research and human application has demonstrated good and useful motor function after ventral root avulsion followed by spinal cord reimplantation. Recently, sensory return could be demonstrated following spinal cord surgery bypassing the injured primary sensory neuron. Experimental data showed that most of the recovery depended on new growth reinnervating peripheral receptors. Restored sensory function and the return of spinal reflex was demonstrated by electrophysiology and functional magnetic resonance imaging of human cortex. This spinal cord surgery is a unique treatment of central nervous system injury resulting in useful functional return. Further improvements will not depend on surgical improvements. Adjuvant therapy aiming at ameliorating the activity in retinoic acid elements in dorsal root ganglion neurons could be a new therapeutic avenue in restoring spinal cord circuits after nerve root avulsion injury.

Intramedullary spinal cord metastasis from pancreatic neuroendocrine tumor

Intramedullary spinal cord metastasis(ISCM) is very rare and its optimal treatment remains controversial. Pancreatic neuroendocrine tumor(pNET) is a rare tumor that usually presents with hepatic metastasis. Hepatic failure due to tumor progression is the major cause of death in cases of pNET. To date,no report has described a case of ISCM from pNET. Although spinal cord metastasis of a solid tumor is uncommon,it is a critical condition that can cause a potentially irreversible loss of neurologic function. Here,we report the case of a 45-year-old man who presented with leg weakness and voiding difficulty,and was found to have ISCM from pNET. Surgical treatment prevented further neurological deterioration. This is the first case report of ISCM from pNET.

Can neck swelling lead to spinal cord compression?

Spinal cord compression(SCC) caused by cervical spinal canal invasion of a pulmonary sarcomatoid carcinoma metastasis has never been reported previously. A 59-year-old man, with a history of pulmonary carcinosarcoma, developed over several weeks important neck swelling. Admitted to our division with severe tetraparesis he underwent a cervical spine computed tomography scan that showed a large cervical mass measuring 11 cm × 27 cm × 17 cm with SCC, extending from the occiput to C7. Emergency spinal cord decompression was performed leading to minor neurological improvement. Poor outcome was due to the unusual clinical sign that led to late diagnosis and treatment.

Surgical Management of Intramedullary Spinal Cord Tumors: Surgical Resection and Prognosis

BACKGROUND & OBJECTIVE: The majority of intramedullary spinal cord tumors (IMSCT) are low-grade gliomas. Radical resection for IMSCTs remains challenging. Recently, improved neuroimaging and advanced microsurgical technique have made great success in surgical management of the intramedullary spinal cord tumors. METH-ODS & RESULTS: Twenty-nine patients with intramedullary spinal cord tumors were treated by radical resection dur-ing the past 4 years in our institute. The histological results were as follows: 12 ependymomas, 4 astrocytomas, 4 heman-gioblastomas, 4 epidermoids, 1 cavernoma, 2 lipomas, 2 metastatics. A gross -total resection (】 95%) was achieved in 25 surgical procedures. Subtotal resections (80-95% ) were performed in 4 cases. There was no surgical death.When comparing the preoperative and 3-month postoperative functional grades, 12 patients were stable 14 improved,and 3 deteriorated. Patients with either no deficit or only mild deficit before surgery were rarely impaired by the proce-dure, reinforcing the importance of early diagnosis and treatment. The major determinant of long-term survival was histologi-cal composition of the tumor. Patients in whom an IMSCT was only partially resected (【80% ) fared significantly worse. CONCLUSIONS: The long-term survival and quality of life for patients with low-grade gliomas treated by radi-cal resection alone is comparable or superior to minimal resection plus radiotherapy. The optimal therapy for patients with high-grade glioma is yet to be determined. For benign lesion, such as hemangioblastoma and cavernoma could be cured by total resection of the tumor. For lipoma and epidermoid, fibrous adhesions to the cord make total removal difficult,and thus, removal is not the goal of surgery. The carbon dioxide laser is particularly useful during surgery for this lesion.

机器人辅助手术治疗脊柱骨折伴脊髓神经损伤的研究进展

脊柱骨折作为骨科常见创伤之一,多由直接或间接外力引起,主要累及脊柱和周围软组织。脊柱骨折后正常生理结构改变,常导致脊髓神经受损、受压,且由于椎管内含脆弱神经,解剖结构复杂,对于手术精准性要求较高。机器人手术系统拥有自由度较高的机械臂,术者可利用计算机实时导航跟踪、动态监测进针的精度与安全性,并能提高穿刺及置钉成功率,避免二次骨质破坏,减轻术者工作负荷。同时,机器人辅助治疗和康复方式在临床治疗中的应用,可为患者提供持续性神经治疗和康复,增加患者肌肉活动性,改善神经损伤情况,有利于患者肢体功能康复。本研究主要分析机器人辅助手术在脊柱骨折伴脊髓神经损伤中的应用,旨在为脊柱骨折伴脊髓神经损伤治疗提供指导。

脊髓融合术理念在脊髓损伤的诊疗方面的专家共识

目前,国内外仍未就脊髓融合术(Spinal Cord Fusion,SCF)在脊髓损伤(Spinal Cord Injury,SCI)修复中的应用达成专家共识。广西中西医结合学会修复重建显微外科分会专家组牵头制定了SCF应用于SCI修复的专家共识,旨在为SCI截瘫患者的神经功能重建提供指导。通过文献研究、临床试验和多轮会议讨论,首次系统阐述了SCF的适应症、手术方法和术后康复治疗,以实现该技术的合理化和规范化应用。为临床医师提供了标准化的指导,促进了SCF技术的临床实践推广和应用。

针药结合治疗脊髓占位术后神经源性膀胱验案一则

神经源性膀胱(Neurogenic Bladder,NB)是一类由神经系统(中枢、周围)病变引起的膀胱和/或尿道功能障碍(储尿和/或排尿的功能障碍),从而产生一系列下尿路症状和并发症的疾病总称,尿不畅或尿潴留是其最常见的症状。临床主要通过间歇导尿和留置尿管进行治疗,但都存在不同的缺点而影响疗效。现代医学研究发现,中西医结合疗法是临床上值得尝试的选择,可以改善患者预后,提高患者生活质量。中医学认为,本病与肾和膀胱关系密切,其病因主要是肾与膀胱气化不利,且根据其不同临床表现,将本病归属于“癃闭”和“遗溺”范畴,临床常见的中医治疗方法包括中药汤剂、针灸疗法、推拿按摩等,也可以多法并用,共同发挥温补肾阳、助膀胱气化的效果。现代研究证实,桥脑排尿中心、骶脊髓和下尿路之间的协同作用对于控制排尿至关重要,针刺可以激发神经调节功能,加强逼尿肌和膀胱括约肌的协同反射活动,改善尿动力学,加快下尿路的气血循环,促进排尿功能恢复。中药、艾灸也在NB的治疗过程中发挥着重要作用。天津中医药大学针灸科丁淑强主任医师以针药结合治疗脊髓占位术后NB取得良好疗效。现通过医案介绍,为各位同道提供临床参考。

手术治疗颈脊髓中央损伤综合征的预后及相关影响因素分析

目的分析手术治疗颈脊髓中央损伤综合征的预后及相关影响因素。方法回顾性选取2021年2月至2023年2月泸州市人民医院颈脊髓中央损伤综合征患者100例,依据手术预后分为预后良好组(n=70)、预后不良组(n=30)。统计分析两组患者的一般资料[性别、年龄、致伤原因、受伤至手术时间、手术方式、入院和末次随访日本矫形学学会(JOA)评分、美国脊髓损伤协会(ASIA)神经功能评分、ASIA感觉、运动评分、手内肌肌力评分、住院时间、影像学资料等],多元回归分析一般资料与ASIA感觉、运动评分改善率、JOA评分改善率、预后良好的情况,并分析预后良好的相关影响因素、临界值。结果两组患者的性别构成比、病理征、椎间盘突出、后方韧带损伤、发育性颈椎管狭窄、手术方式、受伤至手术时间、住院时间、髓内高信号范围、脊髓受压最大处矢状径、脊髓最大受压程度(MSCC)之间比较,差异均无统计学意义(P>0.05);预后良好组患者的年龄、椎前高信号比率、后纵韧带骨化比率、椎管最狭窄处矢状径、MCC均明显低于预后不良组,差异均有统计学意义(P<0.05);预后良好组患者的入院时手内肌评分、ASIA运动评分和JOA评分均明显高于预后不良组,差异均有统计学意义(P<0.05)。预后良好的相关影响因素包括椎前高信号、椎管最狭窄处百分比、入院时手内肌评分、入院ASIA运动评分、入院JOA评分(P<0.05)。MCC预测手术治疗颈脊髓中央损伤综合征预后的灵敏度和特异度最高(P<0.05)。结论手术治疗颈脊髓中央损伤综合征的预后良好率高,MCC为主要相关影响因素。

颈前路椎间盘切除减压植骨融合术后患者颈长肌和颈伸肌的影像观察

目的观察脊髓型颈椎病患者接受颈前路椎间盘切除减压植骨融合术(anterior cervical discectomy and fusion,ACDF)术后的颈长肌和颈伸肌变化情况,并分析颈长肌和颈伸肌的术后变化与ACDF手术疗效的相关性。方法以该科2016年6月~2021年6月开展单节段ACDF手术的62例脊髓型颈椎病患者作为研究对象,分别于术前、术后3个月、术后1年和末次随访时,进行VAS评分、mJOA评分和NDI指数等疗效指标评价;同时,采用颈椎MRI T2加权像检查并测量其颈长肌和颈伸肌的横截面积(cross section area,CSA),颈长肌的最长径/最短径比值(ratio of long and short lines,RLS)以及颈长肌和颈伸肌的容积。采用Pearson相关性系数对颈长肌和颈伸肌容积与上述疗效指标进行相关性分析。结果62例患者均成功完成单节段ACDF手术且获访24~30个月、平均25.9个月。与术前相比,患者术后3个月、1年和末次随访时的颈肩痛VAS评分、mJOA评分和NDI指数均显著改善(P<0.05)。末次随访时采用Odom标准评价,优38例,良22例,可2例。与术前相比,所有患者术后3个月、1年和末次随访时的颈长肌CSA和颈长肌容积均显著减少(P<0.05),术后3个月、1年和末次随访时的颈长肌RLS均显著增加(P<0.05);颈伸肌CSA和颈伸肌容积在手术前和术后各时间的变化无显著性差异(P>0.05)。经Pearson相关性分析显示,术后3个月、术后1年和末次随访的颈长肌容积与同时期的VAS评分和NDI指数均呈负相关性(P<0.05),与mJOA评分无明确相关性(P>0.05);而颈伸肌容积与同时期的VAS评分、NDI指数和mJOA评分均无明确的相关性(P>0.05)。结论脊髓型颈椎病患者行ACDF手术后,颈长肌可出现一定程度退变,颈伸肌的退变并不显著。颈长肌的退变可对手术预后产生不利影响。

术中神经电生理监测技术在脊柱手术患者中的应用价值

目的研究术中神经电生理监测(IONM)技术在脊柱手术患者中的应用价值,旨在为提升脊柱手术的有效性与安全性提供指导依据。方法选取西安市红会医院和西安大兴医院2022年5月至2023年5月收治的200例拟行脊柱手术患者开展前瞻性研究。以电脑编号奇偶数字法随机分为术中监测组及参考组各100例。术中监测组男55例,女45例;年龄32~74(58.92±10.35)岁;体重指数(BMI)为18~30(23.15±2.09)kg/m^(2)。参考组男57例,女43例;年龄33~73(59.14±10.62)岁;BMI为18~30(23.27±2.15)kg/m^(2)。两组均开展常规脊柱手术,术中监测组术中应用IONM技术,而参考组术中不应用IONM技术。对比两组各项围手术期指标、脊髓神经功能(评估时机为术前1 d及术后7 d)、血清炎症因子水平(评估时机为术前1 d及术后1 d)、术后并发症。统计学方法采用χ^(2)检验、t检验。结果术中监测组术后肛门排气时间、下床活动时间及住院时间均短于参考组[(10.84±1.56)h比(15.20±2.30)h、(3.84±0.69)d比(5.71±0.83)d、(9.47±1.66)d比(12.84±2.30)d],差异均有统计学意义(t=15.69、17.33、11.88,均P<0.05)。两组术后7 d的日本骨科协会评估治疗分数(JOA)评分均较术前1 d高(均P<0.05),且术中监测组高于参考组[(25.94±2.30)分比(21.50±2.57)分],差异有统计学意义(t=12.87,P<0.05)。术中监测组术后并发症发生率低于参考组[6.00%(6/100)比20.00%(20/100)],差异有统计学意义(χ^(2)=8.67,P<0.05)。两组术后1 d血清炎症因子水平虽均较术前1 d高,但术中监测组均较参考组低(均P<0.05)。结论在脊柱手术中应用IONM技术可促进患者早日康复,改善脊髓神经功能,降低并发症发生风险,减轻炎症反应。

急性创伤性颈脊髓损伤术后继发神经源性休克危险因素及预测效能分析

目的 探讨急性创伤性颈脊髓损伤术后继发神经源性休克危险因素并进一步分析相关因素临床预测效能。方法 回顾性纳入2021年6月至2023年6月于本院行手术治疗急性创伤性颈脊髓损伤患者共100例,根据术后是否继发神经源性休克分为休克组(39例)和非休克组(61例);采用单因素和多因素法评估急性创伤性颈脊髓损伤术后继发神经源性休克独立危险因素;描绘ROC曲线分析上述独立危险因素用于急性创伤性颈脊髓损伤术后继发神经源性休克风险预测临床效能。结果 本研究纳入于本院行手术治疗急性创伤性颈脊髓损伤患者共100例,术后继发神经源性休克39例,发生率为39.00%;单因素分析结果显示,是否存在低钠血症、美国脊髓损伤协会损伤分级及24 h尿量均可能与急性创伤性颈脊髓损伤术后继发神经源性休克有关(P<0.05);多因素分析结果显示,低钠血症、美国脊髓损伤协会损伤分级A级及24 h尿量增多均是急性创伤性颈脊髓损伤术后继发神经源性休克独立危险因素(P<0.05);ROC曲线分析结果显示,是否存在低钠血症、美国脊髓损伤协会损伤分级及24 h尿量均可用于急性创伤性颈脊髓损伤术后继发神经源性休克风险预测,且三种指标联合预测效能均显著高于单一指标(P<0.05)。结论 急性创伤性颈脊髓损伤术后继发神经源性休克与是否存在低钠血症、美国脊髓损伤协会损伤分级及24 h尿量关系密切;而上述指标联合在预测术后继发神经源性休克风险方面显示出更佳效能。

激励理论联合协同干预对天玑骨科手术机器人治疗后的颈脊髓损伤患者功能康复和应对倾向的影响

目的:探究激励理论联合协同干预对天玑骨科手术机器人治疗后的颈脊髓损伤患者功能康复和应对倾向的影响。方法:回顾性分析了2021年1月—2023年5月江苏省人民医院收治的60例颈脊髓损伤患者的临床资料,根据治疗方式的不同将所有患者分为观察组(38例,协同干预+激励理论)和对照组(22例,协同干预)。比较两组患者干预前和干预后(6个月)的应对方式、Barthel指数(BI)及功能独立性评定(FIM)情况,并回顾性分析了影响颈脊髓损伤患者的BI功能因素。结果:干预后观察组积极应对、应对倾向、FIM评分、BI指数均高于对照组,消极应对低于对照组,差异具有统计学意义(P<0.05)。干预方式、BI指数、FIM评分、应对倾向、积极应对两两之间为正相关,而消极应对与其均为负相关关系(P<0.05)。应对倾向、FIM评分、积极应对、联合干预均会正向影响BI指数。结论:激励理论联合协同干预对于天玑骨科手术机器人治疗后的颈脊髓损伤患者具有积极作用,可以增加患者应对方式,促进患者功能恢复,提高生活能力,增强信心,促进早日康复。