Inverted pendulum models are commonly used to study the bio-mechanics of biped walkers. In its simplest form, the inverted pendulum consists of a point mass attached to two straight mass-less legs. Most works constrai...Inverted pendulum models are commonly used to study the bio-mechanics of biped walkers. In its simplest form, the inverted pendulum consists of a point mass attached to two straight mass-less legs. Most works constrain the motion of the mass to the sagittal plane, i.e. the plane perpendicular to the ground that contains the direction toward the biped is walking. In this article, we remove this constrain to study the oscillations, the mass experiences in the direction perpendicular to the sagittal plane as the biped walks. While small, these lateral oscillations are unavoidable and of importance in the understanding of balance and stability of walkers, as well as walkers induced oscillations in pedestrian bridges.展开更多
Objective:To study the relationship between spine-pelvis-lower extremities sagittal parameters and disease-related molecules in serum and synovial fluid in patients with knee osteoarthritis. Methods:A total of 65 pati...Objective:To study the relationship between spine-pelvis-lower extremities sagittal parameters and disease-related molecules in serum and synovial fluid in patients with knee osteoarthritis. Methods:A total of 65 patients diagnosed with knee osteoarthritis in Dongguan Tangxia Hospital between May 2013 and December 2016 were collected as OA group, and 70 patients with meniscus and cruciate ligament injury undergoing repair surgery during the same period were collected as the control group. Spine-pelvis-lower extremity sagittal parameters were measured by erect whole spine lateral radiographs. The serum was collected and inflammatory factor contents were measured. The synovial fluid was collected to determine inflammatory factor contents and apoptosis molecule expression.Results: Affected-side PFA and SFA levels of OA group were significantly lower than those of healthy side while FI and ST levels were significantly higher than those of healthy side;serum TNF-α, IL-1β, IL-18, MMP1 and MMP3 contents of OA group were significantly higher than those of control group, negatively correlated with PFA and SFA levels, and positively correlated with FI and ST levels;TNF-α, IL-1β, IL-18, MMP1, MMP3, Fas, FasL, Caveolin-1, NO, CHOP and GRP78 contents in synovial fluid of OA group were significantly higher than those of control group, negatively correlated with PFA and SFA levels, and positively correlated with FI and ST levels. Conclusion: Sagittal parameters of spine-pelvis-lower extremity can be used to evaluate the inflammatory response and apoptosis in patients with knee osteoarthritis.展开更多
目的:经皮椎体后凸成形术(PKP)对骨质疏松性椎体压缩性骨折(OVCF)患者脊柱-骨盆矢状面参数及继发邻椎骨折的影响。方法:选取112例OVCF患者为研究对象,根据手术方式不同分为PVP组[椎体成形术(PVP)治疗]和PKP组(PKP治疗),每组各56例。比...目的:经皮椎体后凸成形术(PKP)对骨质疏松性椎体压缩性骨折(OVCF)患者脊柱-骨盆矢状面参数及继发邻椎骨折的影响。方法:选取112例OVCF患者为研究对象,根据手术方式不同分为PVP组[椎体成形术(PVP)治疗]和PKP组(PKP治疗),每组各56例。比较两组患者围手术期指标(骨水泥量、手术时间及住院时间)、并发症(骨水泥渗漏、术后感染)发生情况、术前及术后6个月疼痛程度[视觉模拟疼痛量表(VAS)评分]、日常生活功能障碍[功能障碍指数问卷表(ODI)评分]、影像学参数[胸椎后凸角(TK)、骨盆倾斜角(PT)、腰椎前凸角(LL)、骶骨倾斜角(SS)、骨盆入射角(PI)、脊柱骶骨角(SSA)]及继发骨折情况。结果:PKP组患者使用骨水泥量、手术时间高于PVP组(P<0.05)。两组患者并发症发生率差异无统计学意义(P>0.05)。术后7 d、6个月,两组患者VAS评分、ODI评分均逐渐降低(P<0.05),且术后7 d PKP组低于PVP组(P<0.05);术后6个月,两组TK均降低(P<0.05),LL、PT、SSA均升高(P<0.05),且术后6个月两组患者TK、LL差异有统计学意义(P<0.05)。两组患者继发骨折率差异无统计学意义(P>0.05)。结论:相较于PVP,PKP治疗OVCF手术时间较长,但可有效减轻患者术后疼痛,改善术后日常活动功能障碍,有利于改善脊柱矢状面平衡,值得临床推广。展开更多
文摘Inverted pendulum models are commonly used to study the bio-mechanics of biped walkers. In its simplest form, the inverted pendulum consists of a point mass attached to two straight mass-less legs. Most works constrain the motion of the mass to the sagittal plane, i.e. the plane perpendicular to the ground that contains the direction toward the biped is walking. In this article, we remove this constrain to study the oscillations, the mass experiences in the direction perpendicular to the sagittal plane as the biped walks. While small, these lateral oscillations are unavoidable and of importance in the understanding of balance and stability of walkers, as well as walkers induced oscillations in pedestrian bridges.
文摘Objective:To study the relationship between spine-pelvis-lower extremities sagittal parameters and disease-related molecules in serum and synovial fluid in patients with knee osteoarthritis. Methods:A total of 65 patients diagnosed with knee osteoarthritis in Dongguan Tangxia Hospital between May 2013 and December 2016 were collected as OA group, and 70 patients with meniscus and cruciate ligament injury undergoing repair surgery during the same period were collected as the control group. Spine-pelvis-lower extremity sagittal parameters were measured by erect whole spine lateral radiographs. The serum was collected and inflammatory factor contents were measured. The synovial fluid was collected to determine inflammatory factor contents and apoptosis molecule expression.Results: Affected-side PFA and SFA levels of OA group were significantly lower than those of healthy side while FI and ST levels were significantly higher than those of healthy side;serum TNF-α, IL-1β, IL-18, MMP1 and MMP3 contents of OA group were significantly higher than those of control group, negatively correlated with PFA and SFA levels, and positively correlated with FI and ST levels;TNF-α, IL-1β, IL-18, MMP1, MMP3, Fas, FasL, Caveolin-1, NO, CHOP and GRP78 contents in synovial fluid of OA group were significantly higher than those of control group, negatively correlated with PFA and SFA levels, and positively correlated with FI and ST levels. Conclusion: Sagittal parameters of spine-pelvis-lower extremity can be used to evaluate the inflammatory response and apoptosis in patients with knee osteoarthritis.
文摘目的:经皮椎体后凸成形术(PKP)对骨质疏松性椎体压缩性骨折(OVCF)患者脊柱-骨盆矢状面参数及继发邻椎骨折的影响。方法:选取112例OVCF患者为研究对象,根据手术方式不同分为PVP组[椎体成形术(PVP)治疗]和PKP组(PKP治疗),每组各56例。比较两组患者围手术期指标(骨水泥量、手术时间及住院时间)、并发症(骨水泥渗漏、术后感染)发生情况、术前及术后6个月疼痛程度[视觉模拟疼痛量表(VAS)评分]、日常生活功能障碍[功能障碍指数问卷表(ODI)评分]、影像学参数[胸椎后凸角(TK)、骨盆倾斜角(PT)、腰椎前凸角(LL)、骶骨倾斜角(SS)、骨盆入射角(PI)、脊柱骶骨角(SSA)]及继发骨折情况。结果:PKP组患者使用骨水泥量、手术时间高于PVP组(P<0.05)。两组患者并发症发生率差异无统计学意义(P>0.05)。术后7 d、6个月,两组患者VAS评分、ODI评分均逐渐降低(P<0.05),且术后7 d PKP组低于PVP组(P<0.05);术后6个月,两组TK均降低(P<0.05),LL、PT、SSA均升高(P<0.05),且术后6个月两组患者TK、LL差异有统计学意义(P<0.05)。两组患者继发骨折率差异无统计学意义(P>0.05)。结论:相较于PVP,PKP治疗OVCF手术时间较长,但可有效减轻患者术后疼痛,改善术后日常活动功能障碍,有利于改善脊柱矢状面平衡,值得临床推广。