Stomachache is one of the most common diseases of digestive system, among which stomach pain of deficiency cold of spleen and stomach is the most common. Acupuncture and moxibustion therapy as an external treatment of...Stomachache is one of the most common diseases of digestive system, among which stomach pain of deficiency cold of spleen and stomach is the most common. Acupuncture and moxibustion therapy as an external treatment of traditional Chinese medicine for relieving stomach pain due to deficiency of spleen and stomach, has the advantages of convenient operation, small adverse reactions and remarkable curative effect, which is easy for patients to accept. In this paper, acupuncture and moxibustion therapy such as moxibustion and warm acupuncture therapy for stomach pain of spleen and stomach deficiency cold type is summarized to provide evidence-based basis for clinical treatment of stomach pain of spleen and stomach deficiency cold type.展开更多
Objective:To summarize Professor Xie's clinical experience in treating the deficiency cold of spleen and stomach type of complex peptic ulcer.Methods:through the observation of the curative effect of the patients ...Objective:To summarize Professor Xie's clinical experience in treating the deficiency cold of spleen and stomach type of complex peptic ulcer.Methods:through the observation of the curative effect of the patients with the deficiency cold of spleen and stomach type of complex peptic ulcer in the outpatient department of liver,spleen and stomach department of our hospital,the dialectical application and clinical experience of Professor Xie Jingri's self-made prescription in clinical practice were summarized.Results:Professor Xie Jingri's self-made prescription can effectively improve the clinical symptoms of patients with the deficiency cold of spleen and stomach type of complex peptic ulcer,and through individual syndrome differentiation and treatment,make the self-made prescription vary from person to person,clinical addition and subtraction,so as to further improve the clinical efficacy of patients.Conclusion:Professor Xie Jingri's self-made prescription is effective in treating complex peptic ulcer of spleen stomach deficiency cold type,which is worthy of further clinical application and promotion.展开更多
OBJECTIVE:To evaluate the efficacy of the extract from Ganjiangdazao recipe(EGR)on functional dyspepsia in rats with spleen-stomach deficiency cold pattern(SSDCP)in terms of Traditional Chinese Medicine,and to investi...OBJECTIVE:To evaluate the efficacy of the extract from Ganjiangdazao recipe(EGR)on functional dyspepsia in rats with spleen-stomach deficiency cold pattern(SSDCP)in terms of Traditional Chinese Medicine,and to investigate its pharmacodynamics.METHODS:Sixty Sprague-Dawley rats were randomly divided into the control group,SSDCP group,low-EGR SSDCP group,high-EGR SSDCP group,probiotics group,EGR group.SSDCP model was induced by gavage with the 0℃edible vinegar.The symptoms and manifestations were scored by method from the relative literature,the ecological changes in cecal microflora was analyzed by 16SrRNA high-throughput sequencing technology,gastric tissues were treated by immunohistochemistry,the levels of related biochemical components related to the gastrointestinal functions were detected by enzyme-linked immunosorbent assay and colorimetry,gastric juice was measured by pH meter,blood pressure measurement by trapping tail method,surface temperature measured by infrared thermal imaging,and the content of 6-gingerol in the serum was determined by liquid-mass chromatography before and after EGR was given.RESULTS:It was found that EGR could effectively relieve the symptoms and manifestations of the SSDCP rats(P<0.05);the value of the relative abundance of Lactobacillus,Streptococcus,Enterococcus and Coprobacillus increased,while the value of the relative abundance of Clostridium decreased(P<0.05)in the cecal microflora in the SSDCP rats after high-EGR administration;It was also found that EGR had no substantial effect on the related biochemical components related to the gastrointestinal functions of in the SSDCP rats;and a certain amount of 6-gingerol was detected in the serum of EGR group.CONCLUSION:The pharmacodynamic site of EGR is the intestinal tract,and the mechanism behind the effect of EGR on SSDCP rats,involves increasing the beneficial bacteria and decreasing the proinflammatory bacteria in the intestinal tract.The blood pharmacodynamics of EGR remains to be further studied in the future.展开更多
文摘Stomachache is one of the most common diseases of digestive system, among which stomach pain of deficiency cold of spleen and stomach is the most common. Acupuncture and moxibustion therapy as an external treatment of traditional Chinese medicine for relieving stomach pain due to deficiency of spleen and stomach, has the advantages of convenient operation, small adverse reactions and remarkable curative effect, which is easy for patients to accept. In this paper, acupuncture and moxibustion therapy such as moxibustion and warm acupuncture therapy for stomach pain of spleen and stomach deficiency cold type is summarized to provide evidence-based basis for clinical treatment of stomach pain of spleen and stomach deficiency cold type.
基金Construction Program of 2016 National Famous Old TCM Experts’Heritage Studio[(2016)No.42]Sixth Batch of National Senior TCM Experts’Academic Experience Inheritance Project[(2017)No.29]+1 种基金Postdoctoral Research Program of Heilongjiang Province(No.LBH-Q17169)National Training Program for Key Talents in TCM Clinical Characteristic Technology Inheritance[(2019)No.36]。
文摘Objective:To summarize Professor Xie's clinical experience in treating the deficiency cold of spleen and stomach type of complex peptic ulcer.Methods:through the observation of the curative effect of the patients with the deficiency cold of spleen and stomach type of complex peptic ulcer in the outpatient department of liver,spleen and stomach department of our hospital,the dialectical application and clinical experience of Professor Xie Jingri's self-made prescription in clinical practice were summarized.Results:Professor Xie Jingri's self-made prescription can effectively improve the clinical symptoms of patients with the deficiency cold of spleen and stomach type of complex peptic ulcer,and through individual syndrome differentiation and treatment,make the self-made prescription vary from person to person,clinical addition and subtraction,so as to further improve the clinical efficacy of patients.Conclusion:Professor Xie Jingri's self-made prescription is effective in treating complex peptic ulcer of spleen stomach deficiency cold type,which is worthy of further clinical application and promotion.
基金National Natural Science Foundation of China:Construction of the Qi-Blood-Body Fluid Network Based on the Dynamic Detection of Human Biological Information and Research on the Network's Mechanism of Identification(No.81473553)National Natural Science Foundation of China:Construction of TCM Qi-Function Biological Network Based on the Body Odor and Voice and Research on the Network's Mechanism(No.81573880)National Natural Science Foundation of China:Applied biological basis of accurate measurement of Qi deficiency and Blood deficiency in TCM(No.81873211)。
文摘OBJECTIVE:To evaluate the efficacy of the extract from Ganjiangdazao recipe(EGR)on functional dyspepsia in rats with spleen-stomach deficiency cold pattern(SSDCP)in terms of Traditional Chinese Medicine,and to investigate its pharmacodynamics.METHODS:Sixty Sprague-Dawley rats were randomly divided into the control group,SSDCP group,low-EGR SSDCP group,high-EGR SSDCP group,probiotics group,EGR group.SSDCP model was induced by gavage with the 0℃edible vinegar.The symptoms and manifestations were scored by method from the relative literature,the ecological changes in cecal microflora was analyzed by 16SrRNA high-throughput sequencing technology,gastric tissues were treated by immunohistochemistry,the levels of related biochemical components related to the gastrointestinal functions were detected by enzyme-linked immunosorbent assay and colorimetry,gastric juice was measured by pH meter,blood pressure measurement by trapping tail method,surface temperature measured by infrared thermal imaging,and the content of 6-gingerol in the serum was determined by liquid-mass chromatography before and after EGR was given.RESULTS:It was found that EGR could effectively relieve the symptoms and manifestations of the SSDCP rats(P<0.05);the value of the relative abundance of Lactobacillus,Streptococcus,Enterococcus and Coprobacillus increased,while the value of the relative abundance of Clostridium decreased(P<0.05)in the cecal microflora in the SSDCP rats after high-EGR administration;It was also found that EGR had no substantial effect on the related biochemical components related to the gastrointestinal functions of in the SSDCP rats;and a certain amount of 6-gingerol was detected in the serum of EGR group.CONCLUSION:The pharmacodynamic site of EGR is the intestinal tract,and the mechanism behind the effect of EGR on SSDCP rats,involves increasing the beneficial bacteria and decreasing the proinflammatory bacteria in the intestinal tract.The blood pharmacodynamics of EGR remains to be further studied in the future.