A surface spline function is used to fit a coal seam surface in structural anal ysis in coal geology. From the surface spline function, the first and second partial derivatives can also be derived and used to structur...A surface spline function is used to fit a coal seam surface in structural anal ysis in coal geology. From the surface spline function, the first and second partial derivatives can also be derived and used to structural analysis, especially for recogni tion of the concealed structures. The detection of structures related to faulting is em phasized.展开更多
Modelling and simulation of projectile flight is at the core of ballistic computer software and is essential to the study of performance of rifles and projectiles in various engagement conditions.An effective and repr...Modelling and simulation of projectile flight is at the core of ballistic computer software and is essential to the study of performance of rifles and projectiles in various engagement conditions.An effective and representative numerical model of projectile flight requires a relatively good approximation of the aerodynamics.The aerodynamic coefficients of the projectile model should be described as a series of piecewise polynomial functions of the Mach number that ideally meet the following conditions:they are continuous,differentiable at least once,and have a relatively low degree.The paper provides the steps needed to generate such piecewise polynomial functions using readily available tools,and then compares Piecewise Cubic Hermite Interpolating Polynomial(PCHIP),cubic splines,and piecewise linear functions,and their variant,as potential curve fitting methods to approximate the aerodynamics of a generic small arms projectile.A key contribution of the paper is the application of PCHIP to the approximation of projectile aerodynamics,and its evaluation against a set of criteria.Finally,the paper provides a baseline assessment of the impact of the polynomial functions on flight trajectory predictions obtained with 6-degree-of-freedom simulations of a generic projectile.展开更多
An analysis method based on the fuzzy Lyapunov functions is presented to analyze the stability of the continuous affine fuzzy systems. First, a method is introduced to deal with the consequent part of the fuzzy local ...An analysis method based on the fuzzy Lyapunov functions is presented to analyze the stability of the continuous affine fuzzy systems. First, a method is introduced to deal with the consequent part of the fuzzy local model. Thus, the stability analysis method of the homogeneous fuzzy system can be used for reference. Stability conditions are derived in terms of linear matrix inequalities based on the fuzzy Lyapunov functions and the modified common Lyapunov functions, respectively. The results demonstrate that the stability result based on the fuzzy Lyapunov functions is less conservative than that based on the modified common Lyapunov functions via numerical examples. Compared with the method which does not expand the consequent part, the proposed method is simpler but its feasible region is reduced. Finally, in order to expand the application of the fuzzy Lyapunov functions, the piecewise fuzzy Lyapunov function is proposed, which can be used to analyze the stability for triangular or trapezoidal membership functions and obtain the stability conditions. A numerical example validates the effectiveness of the proposed approach.展开更多
Over the last few years, there has been a significant increase in attention paid to fractional differential equations, given their wide array of applications in the fields of physics and engineering. The recent develo...Over the last few years, there has been a significant increase in attention paid to fractional differential equations, given their wide array of applications in the fields of physics and engineering. The recent development of using fractional telegraph equations as models in some fields (e.g., the thermal diffusion in fractal media) has heightened the importance of examining the method of solutions for such equations (both approximate and analytic). The present work is designed to serve as a valuable contribution to work in this field. The key objective of this work is to propose a general framework that can be used to guide quadratic spline functions in order to create a numerical method for obtaining an approximation solution using the linear space-fractional telegraph equation. Additionally, the Von Neumann method was employed to measure the stability of the analytical scheme, which showed that the proposed method is conditionally stable. What’s more, the proposal contains a numerical example that illustrates how the proposed method can be implemented practically, whilst the error estimates and numerical stability results are discussed in depth. The findings indicate that the proposed model is highly effective, convenient and accurate for solving the relevant problems and is suitable for use with approximate solutions acquired through the two-dimensional differential transform method that has been developed for linear partial differential equations with space- and time-fractional derivatives.展开更多
This paper relates to the deep research on the Splinc Model Method of KED analysis. With the use of cubic B-splinc function as a link’s transverse deflection interpolation function, the principle of virtual displacem...This paper relates to the deep research on the Splinc Model Method of KED analysis. With the use of cubic B-splinc function as a link’s transverse deflection interpolation function, the principle of virtual displacement is presented as a basic theory for the general formulation of the equations of motion, and thus abandoned the kinematic assumption and the instantaneous structure assumption which arc used in the Spline Model Method. In thc same time, the nonlinear terms sue as coupling terms between thc rigid body motion and elastic deformation arc included. New member’s spline models are established. Mass matrix, Coriolis mass matrix, normal and tangential mass matrix, linear stiffness matrix, nonlinear stiffness matrix and rotation matrix arc derived. The kinematic differential equations of a member and system are deduced in the end. The Newmark direct integration method is used as the solution scheme of the kinematic differential equations to get the periodic response.展开更多
In numerical analysis, it is significant to approximate the linear functional Ef=sum from i=0 to m-1([integral from a to b(a<sub>1</sub>(x)f<sup>1</sup>(x)dx+ sum from f=0 to i<sub>1&...In numerical analysis, it is significant to approximate the linear functional Ef=sum from i=0 to m-1([integral from a to b(a<sub>1</sub>(x)f<sup>1</sup>(x)dx+ sum from f=0 to i<sub>1</sub>(b<sub>1</sub>f<sup>1</sup>(x<sub>1</sub>))]) by a simpler linear functional Lf=sum from i=1 to m(a<sub>1</sub>f(x<sub>1</sub>)) In this paper, making use of natural Tchebysheff spline function, we give existence theorem and uniqueness theorem of L that is exact for the degree m to F; we also give three sufficient and necessary conditions in which L is the Sard best approximation to F.展开更多
The objective of this paper is to present a review of different calibration and classification methods for functional data in the context of chemometric applications. In chemometric, it is usual to measure certain par...The objective of this paper is to present a review of different calibration and classification methods for functional data in the context of chemometric applications. In chemometric, it is usual to measure certain parameters in terms of a set of spectrometric curves that are observed in a finite set of points (functional data). Although the predictor variable is clearly functional, this problem is usually solved by using multivariate calibration techniques that consider it as a finite set of variables associated with the observed points (wavelengths or times). But these explicative variables are highly correlated and it is therefore more informative to reconstruct first the true functional form of the predictor curves. Although it has been published in several articles related to the implementation of functional data analysis techniques in chemometric, their power to solve real problems is not yet well known. Because of this the extension of multivariate calibration techniques (linear regression, principal component regression and partial least squares) and classification methods (linear discriminant analysis and logistic regression) to the functional domain and some relevant chemometric applications are reviewed in this paper.展开更多
We consider a functional partially linear additive model that predicts a functional response by a scalar predictor and functional predictors. The B-spline and eigenbasis least squares estimator for both the parametric...We consider a functional partially linear additive model that predicts a functional response by a scalar predictor and functional predictors. The B-spline and eigenbasis least squares estimator for both the parametric and the nonparametric components proposed. In the final of this paper, as a result, we got the variance decomposition of the model and establish the asymptotic convergence rate for estimator.展开更多
Functional near-infrared spectroscopy(fNIRS)is a neuroimaging technology which is suitable for psychiatric patients.Several fNIRS studies have found abnormal brain activations during cognitive tasks in elderly depress...Functional near-infrared spectroscopy(fNIRS)is a neuroimaging technology which is suitable for psychiatric patients.Several fNIRS studies have found abnormal brain activations during cognitive tasks in elderly depression.In this paper,we proposed a discriminative model of multivariate pattern classification based on fNIRS signals to distinguish elderly depressed patients from healthy controls.This model used the brain activation patterns during a verbal fluency task as features of classification.Then Pseudo-Fisher Linear Discriminant Analysis was performed on the feature space to generate discriminative model.Using leave-one-out(LOO)cross-validation,our results showed a correct classification rate of 88%.The discriminative model showed its ability to identify people with elderly depression and suggested that fNIRS may be an efficient clinical tool for diagnosis of depression.This study may provide the first step for the development of neuroimaging biomarkers based on fNIRS in psychiatric disorders.展开更多
Mild cognitive impairment(MCI)is a precursor to Alzheimer’s disease.It is imperative to develop a proper treatment for this neurological disease in the aging society.This observational study investigated the effects ...Mild cognitive impairment(MCI)is a precursor to Alzheimer’s disease.It is imperative to develop a proper treatment for this neurological disease in the aging society.This observational study investigated the effects of acupuncture therapy on MCI patients.Eleven healthy individuals and eleven MCI patients were recruited for this study.Oxy-and deoxy-hemoglobin signals in the prefrontal cortex during working-memory tasks were monitored using functional near-infrared spectroscopy.Before acupuncture treatment,working-memory experiments were conducted for healthy control(HC)and MCI groups(MCI-0),followed by 24 sessions of acupuncture for the MCI group.The acupuncture sessions were initially carried out for 6 weeks(two sessions per week),after which experiments were performed again on the MCI group(MCI-1).This was followed by another set of acupuncture sessions that also lasted for 6 weeks,after which the experiments were repeated on the MCI group(MCI-2).Statistical analyses of the signals and classifications based on activation maps as well as temporal features were performed.The highest classification accuracies obtained using binary connectivity maps were 85.7%HC vs.MCI-0,69.5%HC vs.MCI-1,and 61.69%HC vs.MCI-2.The classification accuracies using the temporal features mean from 5 seconds to 28 seconds and maximum(i.e,max(5:28 seconds))values were 60.6%HC vs.MCI-0,56.9%HC vs.MCI-1,and 56.4%HC vs.MCI-2.The results reveal that there was a change in the temporal characteristics of the hemodynamic response of MCI patients due to acupuncture.This was reflected by a reduction in the classification accuracy after the therapy,indicating that the patients’brain responses improved and became comparable to those of healthy subjects.A similar trend was reflected in the classification using the image feature.These results indicate that acupuncture can be used for the treatment of MCI patients.展开更多
Traumatic brain injury(TBI) at a young age can lead to the development of long-term functional impairments. Severity of injury is well demonstrated to have a strong influence on the extent of functional impairments;ho...Traumatic brain injury(TBI) at a young age can lead to the development of long-term functional impairments. Severity of injury is well demonstrated to have a strong influence on the extent of functional impairments;however, identification of specific magnetic resonance imaging(MRI) biomarkers that are most reflective of injury severity and functional prognosis remain elusive. Therefore, the objective of this study was to utilize advanced statistical approaches to identify clinically relevant MRI biomarkers and predict functional outcomes using MRI metrics in a translational large animal piglet TBI model. TBI was induced via controlled cortical impact and multiparametric MRI was performed at 24 hours and 12 weeks post-TBI using T1-weighted, T2-weighted, T2-weighted fluid attenuated inversion recovery, diffusion-weighted imaging, and diffusion tensor imaging. Changes in spatiotemporal gait parameters were also assessed using an automated gait mat at 24 hours and 12 weeks post-TBI. Principal component analysis was performed to determine the MRI metrics and spatiotemporal gait parameters that explain the largest sources of variation within the datasets. We found that linear combinations of lesion size and midline shift acquired using T2-weighted imaging explained most of the variability of the data at both 24 hours and 12 weeks post-TBI. In addition, linear combinations of velocity, cadence, and stride length were found to explain most of the gait data variability at 24 hours and 12 weeks post-TBI. Linear regression analysis was performed to determine if MRI metrics are predictive of changes in gait. We found that both lesion size and midline shift are significantly correlated with decreases in stride and step length. These results from this study provide an important first step at identifying relevant MRI and functional biomarkers that are predictive of functional outcomes in a clinically relevant piglet TBI model. This study was approved by the University of Georgia Institutional Animal Care and Use Committee(AUP: A2015 11-001) on December 22, 2015.展开更多
Multiresolution analysis of wavelet theory can give an effective way to describe the information at various levels of approximations or different resolutions, based on spline wavelet analysis,so weight function is ort...Multiresolution analysis of wavelet theory can give an effective way to describe the information at various levels of approximations or different resolutions, based on spline wavelet analysis,so weight function is orthonormally projected onto a sequence of closed spline subspaces, and is viewed at various levels of approximations or different resolutions. Now, the useful new way to research weight function is found, and the numerical result is given.展开更多
In this paper, we define a functional optimization problem corresponding to smooth functions which its optimal solution is first derivative of these functions in a domain. These functional optimization problems are ap...In this paper, we define a functional optimization problem corresponding to smooth functions which its optimal solution is first derivative of these functions in a domain. These functional optimization problems are applied for non-smooth functions which by solving these problems we obtain a kind of generalized first derivatives. For this purpose, a linear programming problem corresponding functional optimization problem is obtained which their optimal solutions give the approximate generalized first derivative. We show the efficiency of our approach by obtaining derivative and generalized derivative of some smooth and nonsmooth functions respectively in some illustrative examples.展开更多
This paper presents a new kind of spline surfaces, named non-uniform algebraic- trigonometric T-spline surfaces (NUAT T-splines for short) of odd hi-degree. The NUAT T- spline surfaces are defined by applying the T-...This paper presents a new kind of spline surfaces, named non-uniform algebraic- trigonometric T-spline surfaces (NUAT T-splines for short) of odd hi-degree. The NUAT T- spline surfaces are defined by applying the T-spline framework to the non-uniform algebraic- trigonometric B-spline surfaces (NUAT B-spline surfaces). Based on the knot insertion algorithm of the NUAT B-splines, a local refinement algorithm for the NUAT T-splines is given. This algorithm guarantees that the resulting control grid is a T-mesh as the original one. Finally, we prove that, for any NUAT T-spline of odd hi-degree, the linear independence of its blending functions can be determined by computing the rank of the NUAT T-spline-to-NUAT B-spline transformation matrix.展开更多
A structured perturbation analysis of the least squares problem is considered in this paper.The new error bound proves to be sharper than that for general perturbations. We apply the new error bound to study sensitivi...A structured perturbation analysis of the least squares problem is considered in this paper.The new error bound proves to be sharper than that for general perturbations. We apply the new error bound to study sensitivity of changing the knots for curve fitting of interest rate term structure by cubic spline.Numerical experiments are given to illustrate the sharpness of this bound.展开更多
The problem of the robust D-stability analysis for linear systems with parametric uncertainties is addressed. For matrix polytopes, new conditions via the affine parameter-dependent Lyapunov function of uncertain syst...The problem of the robust D-stability analysis for linear systems with parametric uncertainties is addressed. For matrix polytopes, new conditions via the affine parameter-dependent Lyapunov function of uncertain systems are developed with the benefit of the scalar multi-convex function. To be convenient for applications, such conditions are simplified into new linear matrix inequality (LMI) conditions, which can be solved by the powerful LMI toolbox. Numerical examples are provided to indicate that this new approach is less conservative than previous results for Hurwitz stability, Schur stability and D-stability of uncertain systems under certain circumstances.展开更多
In this paper, symbolic code matrix ,constant matrix and count matrix are defined .The first twomatrices are used to describe the elemental expression of augmented matrix and the nede admittance equa-tion is thus obta...In this paper, symbolic code matrix ,constant matrix and count matrix are defined .The first twomatrices are used to describe the elemental expression of augmented matrix and the nede admittance equa-tion is thus obtained. The third matrix is used to obtain the incoming degree matrix, and according to thematrix all the 1- factors of the Coates graph are given. By using the data code, the determinant is expandedand the same items in the expansion are merged. Thus the symbolic network function in which no term can-cellation occurs is generated.展开更多
A continuous-time Model Predictive Controller was proposed using Kautz function in order to improve the performance of Load Frequency Control(LFC).A dynamic model of an interconnected power system was used for Model P...A continuous-time Model Predictive Controller was proposed using Kautz function in order to improve the performance of Load Frequency Control(LFC).A dynamic model of an interconnected power system was used for Model Predictive Controller(MPC)design.MPC predicts the future trajectory of the dynamic model by calculating the optimal closed loop feedback gain matrix.In this paper,the optimal closed loop feedback gain matrix was calculated using Kautz function.Being an Orthonormal Basis Function(OBF),Kautz function has an advantage of solving complex pole-based nonlinear system.Genetic Algorithm(GA)was applied to optimally tune the Kautz function-based MPC.A constraint based on phase plane analysis was implemented with the cost function in order to improve the robustness of the Kautz function-based MPC.The proposed method was simulated with three area interconnected power system and the efficiency of the proposed method was measured and exhibited by comparing with conventional Proportional and Integral(PI)controller and Linear Quadratic Regulation(LQR).展开更多
Many products always operate under various complex environment conditions. To describe the dynamic influence of environment factors on their reliability, a method of reliability sensitivity analysis is proposed. In th...Many products always operate under various complex environment conditions. To describe the dynamic influence of environment factors on their reliability, a method of reliability sensitivity analysis is proposed. In this method, the location parameter is assumed as a function of relevant environment variables while the scale parameter is assumed as an unknown positive constant. Then, the location parameter function is constructed by using the method of radial basis function. Using the varied environment test data, the log-likelihood function is transformed to a generalized linear expression by describing the indicator as Poisson variable. With the generalized linear model, the maximum likelihood estimations of the model coefficients are obtained. With the reliability model, the reliability sensitivity is obtained. An instance analysis shows that the method is feasible to analyze the dynamic variety characters of reliability along with environment factors and is straightforward for engineering application.展开更多
In this study, we analyze brain activity data describing functional magnetic resonance imaging (MRI) imaging of 820 subjects with each subject being scanned at 4 different times. This multiple scanning gives us an opp...In this study, we analyze brain activity data describing functional magnetic resonance imaging (MRI) imaging of 820 subjects with each subject being scanned at 4 different times. This multiple scanning gives us an opportunity to observe the consistency of imaging characteristics within the subjects as compared to the variability across the subjects. The most consistent characteristics are then used for the purpose of predicting subjects’ traits. We concentrate on four predictive methods (Regression, Logistic Regression, Linear Discriminant Analysis and Random Forest) in order to predict subjects’ traits such as gender and age based on the brain activities observed between brain regions. Those predictions are done based on the adjusted communication activity among the brain regions, as assessed from 4 scans of each subject. Due to a large number of such communications among the 116 brain regions, we performed a preliminary selection of the most promising pairs of brain regions. Logistic Regression performed best in classifying the subject gender based on communication activity among the brain regions. The accuracy rate was 85.6 percent for an AIC step-wise selected Logistic Regression model. On the other hand, the Logistic Regression model maintaining the entire set of ranked predictor was capable of getting an 87.7 percent accuracy rate. It is interesting to point out that the model with the AIC selected features was better classifying males, whereas the complete ranked model was better classifying females. The Random Forest technique performed best for prediction of age (grouped within five categories as provided by the original data) with 48.8 percent accuracy rate. Any set of predictors between 200 and 1600 was presenting similar rates of accuracy.展开更多
文摘A surface spline function is used to fit a coal seam surface in structural anal ysis in coal geology. From the surface spline function, the first and second partial derivatives can also be derived and used to structural analysis, especially for recogni tion of the concealed structures. The detection of structures related to faulting is em phasized.
文摘Modelling and simulation of projectile flight is at the core of ballistic computer software and is essential to the study of performance of rifles and projectiles in various engagement conditions.An effective and representative numerical model of projectile flight requires a relatively good approximation of the aerodynamics.The aerodynamic coefficients of the projectile model should be described as a series of piecewise polynomial functions of the Mach number that ideally meet the following conditions:they are continuous,differentiable at least once,and have a relatively low degree.The paper provides the steps needed to generate such piecewise polynomial functions using readily available tools,and then compares Piecewise Cubic Hermite Interpolating Polynomial(PCHIP),cubic splines,and piecewise linear functions,and their variant,as potential curve fitting methods to approximate the aerodynamics of a generic small arms projectile.A key contribution of the paper is the application of PCHIP to the approximation of projectile aerodynamics,and its evaluation against a set of criteria.Finally,the paper provides a baseline assessment of the impact of the polynomial functions on flight trajectory predictions obtained with 6-degree-of-freedom simulations of a generic projectile.
基金Specialized Research Fund for the Doctoral Program of Higher Education ( No. 20090092110051)the Key Project of Chinese Ministry of Education ( No. 108060)the National Natural Science Foundation of China ( No. 51076027, 51036002, 51106024)
文摘An analysis method based on the fuzzy Lyapunov functions is presented to analyze the stability of the continuous affine fuzzy systems. First, a method is introduced to deal with the consequent part of the fuzzy local model. Thus, the stability analysis method of the homogeneous fuzzy system can be used for reference. Stability conditions are derived in terms of linear matrix inequalities based on the fuzzy Lyapunov functions and the modified common Lyapunov functions, respectively. The results demonstrate that the stability result based on the fuzzy Lyapunov functions is less conservative than that based on the modified common Lyapunov functions via numerical examples. Compared with the method which does not expand the consequent part, the proposed method is simpler but its feasible region is reduced. Finally, in order to expand the application of the fuzzy Lyapunov functions, the piecewise fuzzy Lyapunov function is proposed, which can be used to analyze the stability for triangular or trapezoidal membership functions and obtain the stability conditions. A numerical example validates the effectiveness of the proposed approach.
文摘Over the last few years, there has been a significant increase in attention paid to fractional differential equations, given their wide array of applications in the fields of physics and engineering. The recent development of using fractional telegraph equations as models in some fields (e.g., the thermal diffusion in fractal media) has heightened the importance of examining the method of solutions for such equations (both approximate and analytic). The present work is designed to serve as a valuable contribution to work in this field. The key objective of this work is to propose a general framework that can be used to guide quadratic spline functions in order to create a numerical method for obtaining an approximation solution using the linear space-fractional telegraph equation. Additionally, the Von Neumann method was employed to measure the stability of the analytical scheme, which showed that the proposed method is conditionally stable. What’s more, the proposal contains a numerical example that illustrates how the proposed method can be implemented practically, whilst the error estimates and numerical stability results are discussed in depth. The findings indicate that the proposed model is highly effective, convenient and accurate for solving the relevant problems and is suitable for use with approximate solutions acquired through the two-dimensional differential transform method that has been developed for linear partial differential equations with space- and time-fractional derivatives.
文摘This paper relates to the deep research on the Splinc Model Method of KED analysis. With the use of cubic B-splinc function as a link’s transverse deflection interpolation function, the principle of virtual displacement is presented as a basic theory for the general formulation of the equations of motion, and thus abandoned the kinematic assumption and the instantaneous structure assumption which arc used in the Spline Model Method. In thc same time, the nonlinear terms sue as coupling terms between thc rigid body motion and elastic deformation arc included. New member’s spline models are established. Mass matrix, Coriolis mass matrix, normal and tangential mass matrix, linear stiffness matrix, nonlinear stiffness matrix and rotation matrix arc derived. The kinematic differential equations of a member and system are deduced in the end. The Newmark direct integration method is used as the solution scheme of the kinematic differential equations to get the periodic response.
文摘In numerical analysis, it is significant to approximate the linear functional Ef=sum from i=0 to m-1([integral from a to b(a<sub>1</sub>(x)f<sup>1</sup>(x)dx+ sum from f=0 to i<sub>1</sub>(b<sub>1</sub>f<sup>1</sup>(x<sub>1</sub>))]) by a simpler linear functional Lf=sum from i=1 to m(a<sub>1</sub>f(x<sub>1</sub>)) In this paper, making use of natural Tchebysheff spline function, we give existence theorem and uniqueness theorem of L that is exact for the degree m to F; we also give three sufficient and necessary conditions in which L is the Sard best approximation to F.
文摘The objective of this paper is to present a review of different calibration and classification methods for functional data in the context of chemometric applications. In chemometric, it is usual to measure certain parameters in terms of a set of spectrometric curves that are observed in a finite set of points (functional data). Although the predictor variable is clearly functional, this problem is usually solved by using multivariate calibration techniques that consider it as a finite set of variables associated with the observed points (wavelengths or times). But these explicative variables are highly correlated and it is therefore more informative to reconstruct first the true functional form of the predictor curves. Although it has been published in several articles related to the implementation of functional data analysis techniques in chemometric, their power to solve real problems is not yet well known. Because of this the extension of multivariate calibration techniques (linear regression, principal component regression and partial least squares) and classification methods (linear discriminant analysis and logistic regression) to the functional domain and some relevant chemometric applications are reviewed in this paper.
文摘We consider a functional partially linear additive model that predicts a functional response by a scalar predictor and functional predictors. The B-spline and eigenbasis least squares estimator for both the parametric and the nonparametric components proposed. In the final of this paper, as a result, we got the variance decomposition of the model and establish the asymptotic convergence rate for estimator.
文摘Functional near-infrared spectroscopy(fNIRS)is a neuroimaging technology which is suitable for psychiatric patients.Several fNIRS studies have found abnormal brain activations during cognitive tasks in elderly depression.In this paper,we proposed a discriminative model of multivariate pattern classification based on fNIRS signals to distinguish elderly depressed patients from healthy controls.This model used the brain activation patterns during a verbal fluency task as features of classification.Then Pseudo-Fisher Linear Discriminant Analysis was performed on the feature space to generate discriminative model.Using leave-one-out(LOO)cross-validation,our results showed a correct classification rate of 88%.The discriminative model showed its ability to identify people with elderly depression and suggested that fNIRS may be an efficient clinical tool for diagnosis of depression.This study may provide the first step for the development of neuroimaging biomarkers based on fNIRS in psychiatric disorders.
基金supported by National Research Foundation(NRF)of Korea under the auspices of the Ministry of Science and ICT,Republic of Korea(No.NRF-2020R1A2B5B03096000,to KSH).
文摘Mild cognitive impairment(MCI)is a precursor to Alzheimer’s disease.It is imperative to develop a proper treatment for this neurological disease in the aging society.This observational study investigated the effects of acupuncture therapy on MCI patients.Eleven healthy individuals and eleven MCI patients were recruited for this study.Oxy-and deoxy-hemoglobin signals in the prefrontal cortex during working-memory tasks were monitored using functional near-infrared spectroscopy.Before acupuncture treatment,working-memory experiments were conducted for healthy control(HC)and MCI groups(MCI-0),followed by 24 sessions of acupuncture for the MCI group.The acupuncture sessions were initially carried out for 6 weeks(two sessions per week),after which experiments were performed again on the MCI group(MCI-1).This was followed by another set of acupuncture sessions that also lasted for 6 weeks,after which the experiments were repeated on the MCI group(MCI-2).Statistical analyses of the signals and classifications based on activation maps as well as temporal features were performed.The highest classification accuracies obtained using binary connectivity maps were 85.7%HC vs.MCI-0,69.5%HC vs.MCI-1,and 61.69%HC vs.MCI-2.The classification accuracies using the temporal features mean from 5 seconds to 28 seconds and maximum(i.e,max(5:28 seconds))values were 60.6%HC vs.MCI-0,56.9%HC vs.MCI-1,and 56.4%HC vs.MCI-2.The results reveal that there was a change in the temporal characteristics of the hemodynamic response of MCI patients due to acupuncture.This was reflected by a reduction in the classification accuracy after the therapy,indicating that the patients’brain responses improved and became comparable to those of healthy subjects.A similar trend was reflected in the classification using the image feature.These results indicate that acupuncture can be used for the treatment of MCI patients.
基金Financial support was provided by the University of Georgia Office of the Vice President for Research to FDW。
文摘Traumatic brain injury(TBI) at a young age can lead to the development of long-term functional impairments. Severity of injury is well demonstrated to have a strong influence on the extent of functional impairments;however, identification of specific magnetic resonance imaging(MRI) biomarkers that are most reflective of injury severity and functional prognosis remain elusive. Therefore, the objective of this study was to utilize advanced statistical approaches to identify clinically relevant MRI biomarkers and predict functional outcomes using MRI metrics in a translational large animal piglet TBI model. TBI was induced via controlled cortical impact and multiparametric MRI was performed at 24 hours and 12 weeks post-TBI using T1-weighted, T2-weighted, T2-weighted fluid attenuated inversion recovery, diffusion-weighted imaging, and diffusion tensor imaging. Changes in spatiotemporal gait parameters were also assessed using an automated gait mat at 24 hours and 12 weeks post-TBI. Principal component analysis was performed to determine the MRI metrics and spatiotemporal gait parameters that explain the largest sources of variation within the datasets. We found that linear combinations of lesion size and midline shift acquired using T2-weighted imaging explained most of the variability of the data at both 24 hours and 12 weeks post-TBI. In addition, linear combinations of velocity, cadence, and stride length were found to explain most of the gait data variability at 24 hours and 12 weeks post-TBI. Linear regression analysis was performed to determine if MRI metrics are predictive of changes in gait. We found that both lesion size and midline shift are significantly correlated with decreases in stride and step length. These results from this study provide an important first step at identifying relevant MRI and functional biomarkers that are predictive of functional outcomes in a clinically relevant piglet TBI model. This study was approved by the University of Georgia Institutional Animal Care and Use Committee(AUP: A2015 11-001) on December 22, 2015.
基金theNationalNaturalScienceFoundationofChina (No .50 40 90 0 8)
文摘Multiresolution analysis of wavelet theory can give an effective way to describe the information at various levels of approximations or different resolutions, based on spline wavelet analysis,so weight function is orthonormally projected onto a sequence of closed spline subspaces, and is viewed at various levels of approximations or different resolutions. Now, the useful new way to research weight function is found, and the numerical result is given.
文摘In this paper, we define a functional optimization problem corresponding to smooth functions which its optimal solution is first derivative of these functions in a domain. These functional optimization problems are applied for non-smooth functions which by solving these problems we obtain a kind of generalized first derivatives. For this purpose, a linear programming problem corresponding functional optimization problem is obtained which their optimal solutions give the approximate generalized first derivative. We show the efficiency of our approach by obtaining derivative and generalized derivative of some smooth and nonsmooth functions respectively in some illustrative examples.
基金Supported by the National Natural Science Foundation of China(60933008 and 61272300)
文摘This paper presents a new kind of spline surfaces, named non-uniform algebraic- trigonometric T-spline surfaces (NUAT T-splines for short) of odd hi-degree. The NUAT T- spline surfaces are defined by applying the T-spline framework to the non-uniform algebraic- trigonometric B-spline surfaces (NUAT B-spline surfaces). Based on the knot insertion algorithm of the NUAT B-splines, a local refinement algorithm for the NUAT T-splines is given. This algorithm guarantees that the resulting control grid is a T-mesh as the original one. Finally, we prove that, for any NUAT T-spline of odd hi-degree, the linear independence of its blending functions can be determined by computing the rank of the NUAT T-spline-to-NUAT B-spline transformation matrix.
基金Funds for Major State The work of the second author is partly supported by the Special Basic Research Projects (2005CB321700)the National Science Foundation of China under grant No. 10571031The work of the third author is partly supported by the National Science Foundation of China under grant No. 10571031.
文摘A structured perturbation analysis of the least squares problem is considered in this paper.The new error bound proves to be sharper than that for general perturbations. We apply the new error bound to study sensitivity of changing the knots for curve fitting of interest rate term structure by cubic spline.Numerical experiments are given to illustrate the sharpness of this bound.
基金supported by the National Natural Science Foundation of China (6090405161021002)
文摘The problem of the robust D-stability analysis for linear systems with parametric uncertainties is addressed. For matrix polytopes, new conditions via the affine parameter-dependent Lyapunov function of uncertain systems are developed with the benefit of the scalar multi-convex function. To be convenient for applications, such conditions are simplified into new linear matrix inequality (LMI) conditions, which can be solved by the powerful LMI toolbox. Numerical examples are provided to indicate that this new approach is less conservative than previous results for Hurwitz stability, Schur stability and D-stability of uncertain systems under certain circumstances.
基金The Project Supported by National Natural Science Foundation of China
文摘In this paper, symbolic code matrix ,constant matrix and count matrix are defined .The first twomatrices are used to describe the elemental expression of augmented matrix and the nede admittance equa-tion is thus obtained. The third matrix is used to obtain the incoming degree matrix, and according to thematrix all the 1- factors of the Coates graph are given. By using the data code, the determinant is expandedand the same items in the expansion are merged. Thus the symbolic network function in which no term can-cellation occurs is generated.
文摘A continuous-time Model Predictive Controller was proposed using Kautz function in order to improve the performance of Load Frequency Control(LFC).A dynamic model of an interconnected power system was used for Model Predictive Controller(MPC)design.MPC predicts the future trajectory of the dynamic model by calculating the optimal closed loop feedback gain matrix.In this paper,the optimal closed loop feedback gain matrix was calculated using Kautz function.Being an Orthonormal Basis Function(OBF),Kautz function has an advantage of solving complex pole-based nonlinear system.Genetic Algorithm(GA)was applied to optimally tune the Kautz function-based MPC.A constraint based on phase plane analysis was implemented with the cost function in order to improve the robustness of the Kautz function-based MPC.The proposed method was simulated with three area interconnected power system and the efficiency of the proposed method was measured and exhibited by comparing with conventional Proportional and Integral(PI)controller and Linear Quadratic Regulation(LQR).
文摘Many products always operate under various complex environment conditions. To describe the dynamic influence of environment factors on their reliability, a method of reliability sensitivity analysis is proposed. In this method, the location parameter is assumed as a function of relevant environment variables while the scale parameter is assumed as an unknown positive constant. Then, the location parameter function is constructed by using the method of radial basis function. Using the varied environment test data, the log-likelihood function is transformed to a generalized linear expression by describing the indicator as Poisson variable. With the generalized linear model, the maximum likelihood estimations of the model coefficients are obtained. With the reliability model, the reliability sensitivity is obtained. An instance analysis shows that the method is feasible to analyze the dynamic variety characters of reliability along with environment factors and is straightforward for engineering application.
文摘In this study, we analyze brain activity data describing functional magnetic resonance imaging (MRI) imaging of 820 subjects with each subject being scanned at 4 different times. This multiple scanning gives us an opportunity to observe the consistency of imaging characteristics within the subjects as compared to the variability across the subjects. The most consistent characteristics are then used for the purpose of predicting subjects’ traits. We concentrate on four predictive methods (Regression, Logistic Regression, Linear Discriminant Analysis and Random Forest) in order to predict subjects’ traits such as gender and age based on the brain activities observed between brain regions. Those predictions are done based on the adjusted communication activity among the brain regions, as assessed from 4 scans of each subject. Due to a large number of such communications among the 116 brain regions, we performed a preliminary selection of the most promising pairs of brain regions. Logistic Regression performed best in classifying the subject gender based on communication activity among the brain regions. The accuracy rate was 85.6 percent for an AIC step-wise selected Logistic Regression model. On the other hand, the Logistic Regression model maintaining the entire set of ranked predictor was capable of getting an 87.7 percent accuracy rate. It is interesting to point out that the model with the AIC selected features was better classifying males, whereas the complete ranked model was better classifying females. The Random Forest technique performed best for prediction of age (grouped within five categories as provided by the original data) with 48.8 percent accuracy rate. Any set of predictors between 200 and 1600 was presenting similar rates of accuracy.