A micro-annulus(MA)is defined as a high permeability zone or gap initiating/occurring at the casingcement and cement-formation interfaces during the wellbore life span.An MA can significantly compromise wellbore integ...A micro-annulus(MA)is defined as a high permeability zone or gap initiating/occurring at the casingcement and cement-formation interfaces during the wellbore life span.An MA can significantly compromise wellbore integrity by establishing enhanced fluid flow pathways.This study uses a staged finite element approach to simulate wellbore integrity during various loading steps of wellbore operations under downhole conditions.Particular emphasis is placed on the processes of cement poro-elastic property evolution,volume variation,and pore pressure variation as part of the cement hardening step.The resulting state of stress during the life cycle of a typical injection well(i.e.hardening,completion,and injection)is analyzed to assess the onset and evolution of micro-annuli at various interfaces of the composite wellbore system under downhole conditions.The results show that cement shear failure is observed at the casing-cement interface during pressure testing(excessive wellbore pressure);and tensile debonding failure initiates at the cement-formation interface due to cement shrinkage during hardening and injection-related cooling(thermal cycling).Sensitivity analyses considering several parameters show that:(1)the degree of poro-elastic bulk shrinkage has significant implications for both shear and tensile failure initiation e the less the cement shrinks,the less likely the failure initiation is;(2)cement integrity increases with increasing depth;(3)cement pore pressure evolution has significant implications for tensile failure e if cement pore pressure decreases more,higher temperature differences can be sustained before an MA occurs;and(4)cement temperature fluctuations during hardening promote initiation of debonding failure.In summary,the results presented indicate that establishing downhole conditions to quantitatively analyze MA generation is necessary.The results are different compared to laboratory studies without considering/simulating downhole conditions.The knowledge from this study can raise the awareness of predicting and evaluating MA under downhole conditions and can be used to supplement and improve future laboratory experiments.展开更多
A method is proposed to improve the accuracy of remaining useful life prediction for rolling element bearings,based on a state space model(SSM)with different degradation stages and a particle filter.The model is impro...A method is proposed to improve the accuracy of remaining useful life prediction for rolling element bearings,based on a state space model(SSM)with different degradation stages and a particle filter.The model is improved by a method based on the Paris formula and the Foreman formula allowing the establishment of different degradation stages.The remaining useful life of rolling element bearings can be predicted by the adjusted model with inputs of physical data and operating status information.The late operating trend is predicted by the use of the particle filter algorithm.The rolling bearing full life experimental data validate the proposed method.Further,the prediction result is compared with the single SSM and the Gamma model,and the results indicate that the predicted accuracy of the proposed method is higher with better practicability.展开更多
The migration route of oceanic squid provides critical information for us to understand their spatial and temporal variations.Mark-recapture and electronic tags tend to be problematic during processing.Cephalopod hard...The migration route of oceanic squid provides critical information for us to understand their spatial and temporal variations.Mark-recapture and electronic tags tend to be problematic during processing.Cephalopod hard structures such as the beak,containing abundant ecological information with stable morphology and statolithlike sequences of growth increments,may provide information for studying spatio-temporal distribution.In this study,we developed a method,which is based on elemental concentration of beaks at different ontogenetic stages and sampling locations,to reconstruct the squid migration route.We applied this method to Ommastrephes bartramii in the North Pacific Ocean.Nine trace elements were detected in the rostrum sagittal sections(RSS)of the beak using laser ablation inductively coupled plasma mass spectrometry(LA-ICP-MS).For those elements,significant differences were found between the different ontogenetic stages for phosphorus(P),copper(Cu)and zinc(Zn).Sodium(Na),P and Zn were chosen as indicators of sea surface temperature(SST)and a regression model was estimated.The high probability of occurrence in a particular area represented the possible optimal squid location based on a Bayesian model.A reconstructed migration route in this study,combining all the locations at different ontogenetic stages,was consistent with that hypothesized in previous studies.This study demonstrates that the beak can provide useful information for identifying the migration routes of oceanic squid.展开更多
Breast cancer is the second leading cancer in the world. <span style="font-family:Verdana;">The long-term</span><span style="font-family:Verdana;"> exposure </span><span ...Breast cancer is the second leading cancer in the world. <span style="font-family:Verdana;">The long-term</span><span style="font-family:Verdana;"> exposure </span><span style="font-family:Verdana;">of</span><span style="font-family:Verdana;"> some metallic compounds induces different forms of cancer, including breast cancer. Trace elements are essential metals for the physiological functions of the cell on a molecular level and also contribute </span><span style="font-family:Verdana;">in</span> <span style="font-family:Verdana;">treatment</span><span style="font-family:Verdana;"> of many diseases. </span><span style="font-family:Verdana;">The aim of study was</span><span style="font-family:Verdana;"> to compare the level of essential trace elements, sodium, potassium, calcium, iron, and zinc in breast cancer patients with normal healthy adult women. Total forty-five patients (age range from 25</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">73 years) were included in this study and divided into three groups according to three different stages of breast cancer including tumor-II, tumor-III </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> tumor-IV. Blood was collected from all participants after taking history, clinical data </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> taking consent. However, about fifteen non-cancer healthy women in </span><span style="font-family:Verdana;">age</span><span style="font-family:Verdana;"> range from 26</span></span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">69 years were subjected to this study. The elemental concentrations were determined through atomic absorption spectrophotometer </span><span style="font-family:Verdana;">subsequent to</span><span style="font-family:Verdana;"> microwave-induced acid digestion. The results of Na, K, Zn, Fe, Ca, were observed </span></span><span style="font-family:Verdana;">to </span><span style="font-family:Verdana;">decrease in blood samples of breast cancer patients as compared to non-cancer subjects. The results are reliable with other numerous literature reported studies, the efficiency, and deficiency of these trace metals may contribute </span><span style="font-family:Verdana;">an </span><span style="font-family:Verdana;">important</span><span style="font-family:Verdana;"> role in the progress of breast cancer.</span>展开更多
Morphological and chemical studies on zircon grains from gabbro and granite of the Pingtan magmatic complex, Fujian Province, eastern China, show that there are three stages of zircon growth. The early stage of zircon...Morphological and chemical studies on zircon grains from gabbro and granite of the Pingtan magmatic complex, Fujian Province, eastern China, show that there are three stages of zircon growth. The early stage of zircon growth is characterized by colorlessness, high transparence and birefringence, low and dispersive Ipr and Ipy, weak and homogeneous BSE brightness, lower Hf content and depletion of U, Th and Y; the middle stage is characterized by abruptly increasing lpy, progressively strong and sectoral-zoning BSE brightness, higher Hf content and enrichment of U, Th and Y with Th/U 〉 1; the late stage of growth is characterized by brownish color, poor transparence, low birefringence, highest Ipr and Ipy, middle and oscillatorily-zoning BSE brightness, highest contents of Hf, U and Y with Th/U 〈 1. The stages are considered to be formed in a deep magma chamber, ascent passage and emplacement site, respectively. Due to the more or less long residual time of the magma chamber, the difference in age between the early and late stages of zircon might be great enough to be distinguished, which can be attributed to tectonic constraint for the magnlatism.展开更多
基金The authors would like to thank Chevron ETC for financial support for this study.
文摘A micro-annulus(MA)is defined as a high permeability zone or gap initiating/occurring at the casingcement and cement-formation interfaces during the wellbore life span.An MA can significantly compromise wellbore integrity by establishing enhanced fluid flow pathways.This study uses a staged finite element approach to simulate wellbore integrity during various loading steps of wellbore operations under downhole conditions.Particular emphasis is placed on the processes of cement poro-elastic property evolution,volume variation,and pore pressure variation as part of the cement hardening step.The resulting state of stress during the life cycle of a typical injection well(i.e.hardening,completion,and injection)is analyzed to assess the onset and evolution of micro-annuli at various interfaces of the composite wellbore system under downhole conditions.The results show that cement shear failure is observed at the casing-cement interface during pressure testing(excessive wellbore pressure);and tensile debonding failure initiates at the cement-formation interface due to cement shrinkage during hardening and injection-related cooling(thermal cycling).Sensitivity analyses considering several parameters show that:(1)the degree of poro-elastic bulk shrinkage has significant implications for both shear and tensile failure initiation e the less the cement shrinks,the less likely the failure initiation is;(2)cement integrity increases with increasing depth;(3)cement pore pressure evolution has significant implications for tensile failure e if cement pore pressure decreases more,higher temperature differences can be sustained before an MA occurs;and(4)cement temperature fluctuations during hardening promote initiation of debonding failure.In summary,the results presented indicate that establishing downhole conditions to quantitatively analyze MA generation is necessary.The results are different compared to laboratory studies without considering/simulating downhole conditions.The knowledge from this study can raise the awareness of predicting and evaluating MA under downhole conditions and can be used to supplement and improve future laboratory experiments.
文摘A method is proposed to improve the accuracy of remaining useful life prediction for rolling element bearings,based on a state space model(SSM)with different degradation stages and a particle filter.The model is improved by a method based on the Paris formula and the Foreman formula allowing the establishment of different degradation stages.The remaining useful life of rolling element bearings can be predicted by the adjusted model with inputs of physical data and operating status information.The late operating trend is predicted by the use of the particle filter algorithm.The rolling bearing full life experimental data validate the proposed method.Further,the prediction result is compared with the single SSM and the Gamma model,and the results indicate that the predicted accuracy of the proposed method is higher with better practicability.
基金The National Natural Science Foundation of China under contract No.NSFC4147129the China Postdoctoral Science Foundation under contract No.2017M610277+1 种基金the Key Laboratory of Sustainable Exploitation of Oceanic Fisheries Resources(Shanghai Ocean University),Ministry of Education under contract No.A1-0203-00-2009-6the Fund of Key Laboratory of Open-Sea Fishery Development,Ministry of Agriculture,China under contract LOF 2018-02
文摘The migration route of oceanic squid provides critical information for us to understand their spatial and temporal variations.Mark-recapture and electronic tags tend to be problematic during processing.Cephalopod hard structures such as the beak,containing abundant ecological information with stable morphology and statolithlike sequences of growth increments,may provide information for studying spatio-temporal distribution.In this study,we developed a method,which is based on elemental concentration of beaks at different ontogenetic stages and sampling locations,to reconstruct the squid migration route.We applied this method to Ommastrephes bartramii in the North Pacific Ocean.Nine trace elements were detected in the rostrum sagittal sections(RSS)of the beak using laser ablation inductively coupled plasma mass spectrometry(LA-ICP-MS).For those elements,significant differences were found between the different ontogenetic stages for phosphorus(P),copper(Cu)and zinc(Zn).Sodium(Na),P and Zn were chosen as indicators of sea surface temperature(SST)and a regression model was estimated.The high probability of occurrence in a particular area represented the possible optimal squid location based on a Bayesian model.A reconstructed migration route in this study,combining all the locations at different ontogenetic stages,was consistent with that hypothesized in previous studies.This study demonstrates that the beak can provide useful information for identifying the migration routes of oceanic squid.
文摘Breast cancer is the second leading cancer in the world. <span style="font-family:Verdana;">The long-term</span><span style="font-family:Verdana;"> exposure </span><span style="font-family:Verdana;">of</span><span style="font-family:Verdana;"> some metallic compounds induces different forms of cancer, including breast cancer. Trace elements are essential metals for the physiological functions of the cell on a molecular level and also contribute </span><span style="font-family:Verdana;">in</span> <span style="font-family:Verdana;">treatment</span><span style="font-family:Verdana;"> of many diseases. </span><span style="font-family:Verdana;">The aim of study was</span><span style="font-family:Verdana;"> to compare the level of essential trace elements, sodium, potassium, calcium, iron, and zinc in breast cancer patients with normal healthy adult women. Total forty-five patients (age range from 25</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">73 years) were included in this study and divided into three groups according to three different stages of breast cancer including tumor-II, tumor-III </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> tumor-IV. Blood was collected from all participants after taking history, clinical data </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> taking consent. However, about fifteen non-cancer healthy women in </span><span style="font-family:Verdana;">age</span><span style="font-family:Verdana;"> range from 26</span></span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">69 years were subjected to this study. The elemental concentrations were determined through atomic absorption spectrophotometer </span><span style="font-family:Verdana;">subsequent to</span><span style="font-family:Verdana;"> microwave-induced acid digestion. The results of Na, K, Zn, Fe, Ca, were observed </span></span><span style="font-family:Verdana;">to </span><span style="font-family:Verdana;">decrease in blood samples of breast cancer patients as compared to non-cancer subjects. The results are reliable with other numerous literature reported studies, the efficiency, and deficiency of these trace metals may contribute </span><span style="font-family:Verdana;">an </span><span style="font-family:Verdana;">important</span><span style="font-family:Verdana;"> role in the progress of breast cancer.</span>
基金This work is supported by the National Natural Science Foundation of China (No. 40572038).
文摘Morphological and chemical studies on zircon grains from gabbro and granite of the Pingtan magmatic complex, Fujian Province, eastern China, show that there are three stages of zircon growth. The early stage of zircon growth is characterized by colorlessness, high transparence and birefringence, low and dispersive Ipr and Ipy, weak and homogeneous BSE brightness, lower Hf content and depletion of U, Th and Y; the middle stage is characterized by abruptly increasing lpy, progressively strong and sectoral-zoning BSE brightness, higher Hf content and enrichment of U, Th and Y with Th/U 〉 1; the late stage of growth is characterized by brownish color, poor transparence, low birefringence, highest Ipr and Ipy, middle and oscillatorily-zoning BSE brightness, highest contents of Hf, U and Y with Th/U 〈 1. The stages are considered to be formed in a deep magma chamber, ascent passage and emplacement site, respectively. Due to the more or less long residual time of the magma chamber, the difference in age between the early and late stages of zircon might be great enough to be distinguished, which can be attributed to tectonic constraint for the magnlatism.