BACKGROUND Peroral endoscopic myotomy(POEM)is a promising therapeutic modality for esophageal achalasia worldwide.However,clinical failure and adverse events of POEM have still been concerned.AIM To compare the effica...BACKGROUND Peroral endoscopic myotomy(POEM)is a promising therapeutic modality for esophageal achalasia worldwide.However,clinical failure and adverse events of POEM have still been concerned.AIM To compare the efficacy and safety of a novel mark-guided POEM with standard POEM.METHODS A total of 133 patients with esophageal achalasia who underwent POEM from May 2013 to May 2019 were enrolled in this retrospective study.Of the 133 patients,there were 64 patients in the mark-guided POEM group and 69 patients in the standard POEM group.The clinical success,procedural duration and adverse events were compared between the two groups at 3 mo,12 mo and 24 mo postoperatively.RESULTS Characteristic baseline was similar in the mark-guided POEM group and standard POEM group.The clinical success was comparable between the two groups,ranging from 92%to 98%,at 3 mo,12 mo and 24 mo postoperatively(all P>0.5).Eckart score,Gastroesophageal Reflux Disease Questionnaire score and SF-36 score were not different between the two groups after treatment(all P>0.05).No severe adverse events occurred in the two groups.However,markguided POEM required shorter procedural duration,and less use of proton pump inhibitors and lower incidence of reflux symptoms than the standard POEM(all P<0.001).CONCLUSION Mark-guided POEM and standard POEM were both effective and safe for the treatment of esophageal achalasia.However,the mark-guided POEM was characterized by shorter procedural duration,less use of proton pump inhibitors and lower incidence of reflux symptoms.展开更多
直接零件标识DPM(Direct part marking)技术是实现产品标识的重要于段之一,其与二维条码技术的结合日益密切,已应用于电子与半导体制造、汽车及汽车零部件制造、航空航天制造、军队枪械和资产管理、制药和医疗保健等行业的产品质量追溯...直接零件标识DPM(Direct part marking)技术是实现产品标识的重要于段之一,其与二维条码技术的结合日益密切,已应用于电子与半导体制造、汽车及汽车零部件制造、航空航天制造、军队枪械和资产管理、制药和医疗保健等行业的产品质量追溯和跟踪管理。本文研究了DPM技术标准化发展现状,并对我国DPM技术的标准化提出了建议。展开更多
基金Supported by Natural Science Foundation of Guangdong Province,No.2018A0303100024Shenzhen Health Planning Commission,No.SZXJ2017030
文摘BACKGROUND Peroral endoscopic myotomy(POEM)is a promising therapeutic modality for esophageal achalasia worldwide.However,clinical failure and adverse events of POEM have still been concerned.AIM To compare the efficacy and safety of a novel mark-guided POEM with standard POEM.METHODS A total of 133 patients with esophageal achalasia who underwent POEM from May 2013 to May 2019 were enrolled in this retrospective study.Of the 133 patients,there were 64 patients in the mark-guided POEM group and 69 patients in the standard POEM group.The clinical success,procedural duration and adverse events were compared between the two groups at 3 mo,12 mo and 24 mo postoperatively.RESULTS Characteristic baseline was similar in the mark-guided POEM group and standard POEM group.The clinical success was comparable between the two groups,ranging from 92%to 98%,at 3 mo,12 mo and 24 mo postoperatively(all P>0.5).Eckart score,Gastroesophageal Reflux Disease Questionnaire score and SF-36 score were not different between the two groups after treatment(all P>0.05).No severe adverse events occurred in the two groups.However,markguided POEM required shorter procedural duration,and less use of proton pump inhibitors and lower incidence of reflux symptoms than the standard POEM(all P<0.001).CONCLUSION Mark-guided POEM and standard POEM were both effective and safe for the treatment of esophageal achalasia.However,the mark-guided POEM was characterized by shorter procedural duration,less use of proton pump inhibitors and lower incidence of reflux symptoms.
基金教育部考试中心-英国文化教育协会2020年英语测评科研课题“An Empirical Study into the Validity ofa CSE-based Placement test in China’s Transnational Higher Education”(考协[2020]263号)。
文摘直接零件标识DPM(Direct part marking)技术是实现产品标识的重要于段之一,其与二维条码技术的结合日益密切,已应用于电子与半导体制造、汽车及汽车零部件制造、航空航天制造、军队枪械和资产管理、制药和医疗保健等行业的产品质量追溯和跟踪管理。本文研究了DPM技术标准化发展现状,并对我国DPM技术的标准化提出了建议。
