As a new method, the Level Set method had been developed to compute the interface of two-phase flow. The basic mathematical theory and the detailed method to solve the free surface hydrodynamic problem had been invest...As a new method, the Level Set method had been developed to compute the interface of two-phase flow. The basic mathematical theory and the detailed method to solve the free surface hydrodynamic problem had been investigated. By using the Level Set method, the transformation of a solitary wave over a front step was simulated. The results were in good agreement with laboratory experiments.展开更多
The reflection and transmission of the level step to the water waves in the linear and continuous layer liquid were studied in this paper. Based on the matching method of the eigenfunction and a Boussinesq approximati...The reflection and transmission of the level step to the water waves in the linear and continuous layer liquid were studied in this paper. Based on the matching method of the eigenfunction and a Boussinesq approximation, the analytical expression of the diffraction was obtained and the computing methods of the reflection and transmission en- ergy of the level step were proposed. For the incident wave with a frequency greater than that of the flotage, there is only one mode of plane traveling wave in the flow field. In the range of this greater frequency, the linear and continuous delamination effect will affect the reflection and transmission energy of the floating rectangular box. When the fre- quency of the incident wave is less than the flotage frequency, the energy of the plane traveling wave with infinite modes in the flow field will change into the energy of different modes for each incident wave of different modes.展开更多
In 2010,the first offshore wind turbine with integrated installation was established in Qidong sea area of Jiangsu Province,China,which led to the implementation phase of one-step-installation technique based on the d...In 2010,the first offshore wind turbine with integrated installation was established in Qidong sea area of Jiangsu Province,China,which led to the implementation phase of one-step-installation technique based on the design and construction of large-scale bucket-top-bearing (LSBTB) bucket foundation.The critical technique of LSBTB bucket foundation included self-floating towing,penetration with adjustment of horizontal levelness,removability and one-step-installation.The process of one-step-installation included the prefabrication of LSBTB bucket foundation in onshore construction base,installation and debugging of wind power,overall water transportation of foundation and wind power system,and installation of foundation and offshore wind turbine on the appointed sea area.The cost of one-step-installation technique was about 5 000 Yuan/kW,which was 30%-50% lower than that of the existing technique.The prefabrication of LSBTB bucket foundation took about two months.During the one-step-installation process,the installation and debugging of wind power and overall water transportation need about one to two days in sea area within 35 m depth.After the proposed technique is industrialized,the cost will be further reduced,and the installation capacity is expected to be up to 500 wind turbines per year.展开更多
Current coronavirus pandemic has endangered mankind life. The reported cases are increasing exponentially. Information of plant protein subcellular localization can provide useful clues to develop antiviral drugs. To ...Current coronavirus pandemic has endangered mankind life. The reported cases are increasing exponentially. Information of plant protein subcellular localization can provide useful clues to develop antiviral drugs. To cope with such a catastrophe, a CNN based plant protein subcellular localization predictor called “pLoc_Deep-mPlant” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 95% and its local accuracy is about 90%?-?100%. Both have substantially exceeded the?other existing state-of-the-art predictors. To maximize the convenience for most?experimental scientists, a user-friendly web-server for the new predictor has been established?at?http://www.jci-bioinfo.cn/pLoc_Deep-mPlant/, by which the majority of experimental?scientists can easily obtain their desired data without the need to go through the?mathematical details.展开更多
The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological proc...The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological process within a cell level and provide useful clues to develop antiviral drugs, information of Gram negative bacterial protein subcellular localization is vitally important. In view of this, a CNN based protein subcellular localization predictor called “pLoc_Deep-mGnet” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 98% and its local accuracy is around 94% - 100%. Both are transcending other existing state-of-the-art predictors significantly. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/pLoc_Deep-mGneg/, which will become a very useful tool for fighting pandemic coronavirus and save the mankind of this planet.展开更多
The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. To provide useful clues for developing antiviral ...The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. To provide useful clues for developing antiviral drugs, information of anatomical therapeutic chemicals is vitally important. In view of this, a CNN based predictor called “iATC_Deep-mISF” has been developed. The predictor is particularly useful in dealing with the multi-label systems in which some chemicals may occur in two or more different classes. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/iATC_Deep-mISF/, which will become a very powerful tool for developing effective drugs to fight pandemic coronavirus and save the mankind of this planet.展开更多
The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological proc...The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological process within a cell level and provide useful clues to develop antiviral drugs, information of Gram positive bacteria protein subcellular localization is vitally important. In view of this, a CNN based protein subcellular localization predictor called “pLoc_Deep-mGpos” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 99% and its local accuracy is around 92% - 99%. Both are transcending other existing state-of-the-art predictors significantly. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/pLoc_Deep-mGpos/, which will become a very powerful tool for developing effective drugs to fight pandemic coronavirus and save the mankind of this planet.展开更多
We systematically analyze coseismic responses and post-seismic characteristics of groundwater levels in the Three Gorges well-network to the Ms8.0 Wenchuan earthquake on 12 May 2008. The results indicate that these ch...We systematically analyze coseismic responses and post-seismic characteristics of groundwater levels in the Three Gorges well-network to the Ms8.0 Wenchuan earthquake on 12 May 2008. The results indicate that these characteristics differ among wells. On the conditions of similar borehole configurations, the differences are associated with geological structural sites of wells, burial types of aquifers monitored, and transmissivities of aquifer systems. We explored coseismic and post-seismic step-rise and step-drop mechanical mechanisms and their implication to earthquake prediction. We validated the inference that the residual step-rise zone is a possible earthquake risk zone based on recent seismic activity on the Xiannüshan fault in the area.展开更多
According to the characteristics of frequent water level step-variation in the Wanquan Well, the step-variation frequency change on the time axis can be regarded as a sequence of step-variation. A study of the relati...According to the characteristics of frequent water level step-variation in the Wanquan Well, the step-variation frequency change on the time axis can be regarded as a sequence of step-variation. A study of the relationship between the process of development and evolution of the sequential step-variation and the regional seismicity indicated that the sequential step-variation anomalies are rather better in coincidence with the time, magnitude and frequency of regional seismic activities, which may predict the seismicity trend in months. Furthermore, on this basis, if the water level changes in a characteristic manner, the seismic regime during the time period from several days to 20 days or more may be evaluated. By using the method presented in this paper we had a prediction about the Baotou ML=6.6 earthquake on May 3, 1996. This event occurred within the predicted time span but with a less magnitude and a little location deviation.展开更多
文摘As a new method, the Level Set method had been developed to compute the interface of two-phase flow. The basic mathematical theory and the detailed method to solve the free surface hydrodynamic problem had been investigated. By using the Level Set method, the transformation of a solitary wave over a front step was simulated. The results were in good agreement with laboratory experiments.
文摘The reflection and transmission of the level step to the water waves in the linear and continuous layer liquid were studied in this paper. Based on the matching method of the eigenfunction and a Boussinesq approximation, the analytical expression of the diffraction was obtained and the computing methods of the reflection and transmission en- ergy of the level step were proposed. For the incident wave with a frequency greater than that of the flotage, there is only one mode of plane traveling wave in the flow field. In the range of this greater frequency, the linear and continuous delamination effect will affect the reflection and transmission energy of the floating rectangular box. When the fre- quency of the incident wave is less than the flotage frequency, the energy of the plane traveling wave with infinite modes in the flow field will change into the energy of different modes for each incident wave of different modes.
基金Supported by National High Technology Research and Development Program of China("863"Program,No.2012AA051705)National Natural Science Foundation of China(No.51109160)International Science and Technology Cooperation Program of China(No.2012DFA70490)
文摘In 2010,the first offshore wind turbine with integrated installation was established in Qidong sea area of Jiangsu Province,China,which led to the implementation phase of one-step-installation technique based on the design and construction of large-scale bucket-top-bearing (LSBTB) bucket foundation.The critical technique of LSBTB bucket foundation included self-floating towing,penetration with adjustment of horizontal levelness,removability and one-step-installation.The process of one-step-installation included the prefabrication of LSBTB bucket foundation in onshore construction base,installation and debugging of wind power,overall water transportation of foundation and wind power system,and installation of foundation and offshore wind turbine on the appointed sea area.The cost of one-step-installation technique was about 5 000 Yuan/kW,which was 30%-50% lower than that of the existing technique.The prefabrication of LSBTB bucket foundation took about two months.During the one-step-installation process,the installation and debugging of wind power and overall water transportation need about one to two days in sea area within 35 m depth.After the proposed technique is industrialized,the cost will be further reduced,and the installation capacity is expected to be up to 500 wind turbines per year.
文摘Current coronavirus pandemic has endangered mankind life. The reported cases are increasing exponentially. Information of plant protein subcellular localization can provide useful clues to develop antiviral drugs. To cope with such a catastrophe, a CNN based plant protein subcellular localization predictor called “pLoc_Deep-mPlant” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 95% and its local accuracy is about 90%?-?100%. Both have substantially exceeded the?other existing state-of-the-art predictors. To maximize the convenience for most?experimental scientists, a user-friendly web-server for the new predictor has been established?at?http://www.jci-bioinfo.cn/pLoc_Deep-mPlant/, by which the majority of experimental?scientists can easily obtain their desired data without the need to go through the?mathematical details.
文摘The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological process within a cell level and provide useful clues to develop antiviral drugs, information of Gram negative bacterial protein subcellular localization is vitally important. In view of this, a CNN based protein subcellular localization predictor called “pLoc_Deep-mGnet” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 98% and its local accuracy is around 94% - 100%. Both are transcending other existing state-of-the-art predictors significantly. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/pLoc_Deep-mGneg/, which will become a very useful tool for fighting pandemic coronavirus and save the mankind of this planet.
文摘The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. To provide useful clues for developing antiviral drugs, information of anatomical therapeutic chemicals is vitally important. In view of this, a CNN based predictor called “iATC_Deep-mISF” has been developed. The predictor is particularly useful in dealing with the multi-label systems in which some chemicals may occur in two or more different classes. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/iATC_Deep-mISF/, which will become a very powerful tool for developing effective drugs to fight pandemic coronavirus and save the mankind of this planet.
文摘The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological process within a cell level and provide useful clues to develop antiviral drugs, information of Gram positive bacteria protein subcellular localization is vitally important. In view of this, a CNN based protein subcellular localization predictor called “pLoc_Deep-mGpos” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 99% and its local accuracy is around 92% - 99%. Both are transcending other existing state-of-the-art predictors significantly. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/pLoc_Deep-mGpos/, which will become a very powerful tool for developing effective drugs to fight pandemic coronavirus and save the mankind of this planet.
基金supportedby Basic Science Research Special Item of the Institute of Geology, China Earthquake Administration (NoDF-IGCEA-0608-2-10)Special Research Program of China Earthquake Administration (No. 200808079).
文摘We systematically analyze coseismic responses and post-seismic characteristics of groundwater levels in the Three Gorges well-network to the Ms8.0 Wenchuan earthquake on 12 May 2008. The results indicate that these characteristics differ among wells. On the conditions of similar borehole configurations, the differences are associated with geological structural sites of wells, burial types of aquifers monitored, and transmissivities of aquifer systems. We explored coseismic and post-seismic step-rise and step-drop mechanical mechanisms and their implication to earthquake prediction. We validated the inference that the residual step-rise zone is a possible earthquake risk zone based on recent seismic activity on the Xiannüshan fault in the area.
文摘According to the characteristics of frequent water level step-variation in the Wanquan Well, the step-variation frequency change on the time axis can be regarded as a sequence of step-variation. A study of the relationship between the process of development and evolution of the sequential step-variation and the regional seismicity indicated that the sequential step-variation anomalies are rather better in coincidence with the time, magnitude and frequency of regional seismic activities, which may predict the seismicity trend in months. Furthermore, on this basis, if the water level changes in a characteristic manner, the seismic regime during the time period from several days to 20 days or more may be evaluated. By using the method presented in this paper we had a prediction about the Baotou ML=6.6 earthquake on May 3, 1996. This event occurred within the predicted time span but with a less magnitude and a little location deviation.