Synthesis of (+)-altholactone has been achieved starting from L-tartaric acid using (2S, 3R,4R,5R)-2-hydroxymethyl-3,4-bis(memoxymethoxy)-5-phenyltetrahydrofuran as key intermediate. The key epoxy ring was introduced ...Synthesis of (+)-altholactone has been achieved starting from L-tartaric acid using (2S, 3R,4R,5R)-2-hydroxymethyl-3,4-bis(memoxymethoxy)-5-phenyltetrahydrofuran as key intermediate. The key epoxy ring was introduced by monoperoxyphthalate (MMPP) in high stereoselectivity (8.4:1).展开更多
文摘Synthesis of (+)-altholactone has been achieved starting from L-tartaric acid using (2S, 3R,4R,5R)-2-hydroxymethyl-3,4-bis(memoxymethoxy)-5-phenyltetrahydrofuran as key intermediate. The key epoxy ring was introduced by monoperoxyphthalate (MMPP) in high stereoselectivity (8.4:1).
