Effect of acupuncture at Foot-Yangming Meridian on gastric mucosal blood flow, gastric motiiity and brain-gut peptide

AIM： To observe the effect of acupuncture at Foot- Yangming Meridian on gastric mucosal blood flow （GMBF）, gastric motility and brain-gut peptide. METHODS： Sixty SD rats were randomly divided into 6 groups： normal control group, model group （group with gastric mucosal damage, GMD）, Sibai group （with acupuncture at Sibai point ＋ GMD）, Tianshu group （with acupuncture at Tianshu point ＋ GMD）, Zusanli group （with acupuncture at Zusanli point ＋ GMD） and non-acupoint group （with acupuncture at non-acupoint ＋ GMD）. The GMD model group was induced by infusing pure alcohol into gastric cavity. H2 Gas Clearance Test （HGCT） was used to measure GMBF, the frequency and amplitude of gastric motility were measured by the method of aerocyst, the content of brain-gut peptide in sinus ventriculi and bulbus medullae were detected by radioimmunoassay. RESULTS： Inhibitory effect of the frequency and amplitude of gastric motility were shown in model group, and the rates of frequency and amplitude changes were remarkably different from the normal control group （-19.41 ± 17.21 vs-4.71 ± 10.32, P 〈 0.05; -51.61 ± 29.02 vs 1.81 ± 14.12, P 〈 0.01）. In comparison with control group, the GMBF was 0.52 ± 0.161 mL vs 1.03 ± 0.255 mL per 100g tissue/min, P 〈 0.01, the content of motilin in sinus ventriculi and bulbus medullae was 63.04 ± 7.77 pg/mL vs 72.91 ± 8.42 pg/mL, P 〈 0.05 and 50.96 ± 8.77 pg/mL vs 60.76 ± 8.05 pg/mL, P 〈 0.05, but the content of somatostatin in sinus ventriculi and bulbus medullae was 179.85 ± 43.13 ng/g vs 90.54 ± 40.42 ng/g, P 〈 0.01 and 532.86 ± 122.58 ng/g vs 370.91 ± 76.29 ng/g, P 〈 0.05,respectively. In comparison with model group, the amplitude of gastric motility was 1.52 ± 20.13, -6.52 ± 23.31, 6.92 ± 25.21 vs -51.61 ± 29.02, P 〈 0.01 and GMBF was 0.694 ± 0.160 mL vs 0.893 ± 0.210 mL, 1.038 ± 0.301 mL vs 0.52 ± 0.161 mL per 100g tissue/rain, P 〈 0.01, respectively in Tianshu, Sibai and Zusanli groups, the content of motilin in sinus ventriculi and bulbus medullae was 71.64 ± 9.35 pg/mL vs 63.04 ± 7.77 pg/mL, P 〈 0.05; 58.96 ± 6.69 pg/mL vs 50.96 ± 8.77 pg/mL, P 〈 0.05 in Zusanli group and 72.84 ± 8.62 pg/mL vs 63.04 ± 7.77 pg/mL, P 〈 0.05 in Sibai group, while the content of somatostatin in bulbus medullae in Tianshu, Sibai and Zusanli groups was 480.62 ± 151.69 ng/g, 388.53 ± 155.04 ng/g, 365.76 ± 143.93 ng/g vs 532.86 ± 122.58 ng/g, P 〈 0.05, respectively. CONCLUSION： Electro-acupuncture at acupoints of Foot-Yangming Meridian could enhance the gastric motility, improve GMBF, and regulate the content of motUin and somatostatin in sinus ventriculi and bulbus. The effects of acupuncture on GMBF and gastric motility may be related to the content of brain-gut peptide.

Effect of electro-acupuncture at Foot-Yangming Meridian on somatostatin and expression of somatostatin receptor genes in rabbits with gastric ulcer

AIM： To discuss the protective effect of electroacupuncture at the Foot-Yangming Meridian on gastric mucosal lesion, somatostatin （SS） and the expression of SS receptor genes （SSR1mRNA） in rabbits with gastric ulcer and to further explore the relative specificity of meridians and viscera at gene expression level. METHODS： Forty rabbits were randomly divided into control group （A）, gastric ulcer model group （B）, FootYangming Meridian group （C）, Foot-Shaoyang Meridian group （D） and Foot-Taiyang Meridian group （E）. The gastric ulcer model was prepared by infusing alcohol into stomach. Groups C-E were treated with electroacupuncture at points along the above meridians using meridian stimulating instruments for 7 days respectively. By the end of treatment, the index of gastric ulcer was determined, the amount of epidermal growth factor（EGF） and somatostatin was measured by radioimmunoassay （PJA）. SS-R1mRNA expression in gastric mucosa was determined by RT-PCR. RESULTS： The value of EGF in model group was obviously lower（73.6±14.8 vs 91.3±14.9 pg/mL, P〈 0.01） than that in control group. The index of gastric ulcer, content of SS and expression of SSRtmRNA in gastric mucosa were significantly higher than those in control group （24.88 ± 6.29 vs 8.50 ± 2.98 scores, P〈 0.01; 2978.6 ± 587.6 vs 1852.4 ± 361.7 mIU/mL, P〈 0.01; 2.56±0.25 vs 1.04±0.36, P〈0.01） . The value of EGF in Foot-Yangming Meridian group was higher than that in model group（92.2±6.7 vs 73.6±14.8 pg/mL, P〈 0.01）. The index of gastric ulcer, content of SS and expression of SS-R1mRNA in gastric mucosa were significantlylower than those in control group（10.88±3.23 vs 24.88±6.29 scores, P〈0.01; 1800.2±488 vs 2978.6±587.6 mIU/mL, P 〈 0.01; 1.07±0.08 vs 2.56±0.25mIU/mL, P〈0.01）. Compared to the model group, the content of SS and expression of SSRlmRNA in gastric mucosa in Foot-Shaoyang Meridian group decreased （2441.0±488. vs 2978.6± 587.6 mIU/mL, P〈 0.05; 1.73±0.16 vs 2.56±0.25 mIU/mL, P〈0.01）. But the above parameters in Foot-Taiyang Meridian group did not improve and were significantly different from those in Footoyangming Meridian group （P〈0.05） CONCLUSION： Electro-acupuncture at Foot-Yangming Meridian can protect gastric mocusa against injury. The mechanism may be releted to the regulation of brain-gut peptides and the expression of SSRtmRNA.

Enhanced expression of epidermal growth factor receptor gene in gastric mucosal cells by the serum derived from rats treated with electroacupuncture at stomach meridian acupoints

AIM: To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHODS: The stress-induced gastric mucosal injury in rat model was established by water-immersion and restrained stress methods. 52 rats were randomly divided into: normal group (n = 8), model group (n = 8), model serum group (n = 12), stomach serum group (n = 12), and gallbladder serum group (n = 12). The gastric mucosal cells were separated by pronase-EDTA digestion method and incubated with serum. The EGFR gene expression in gastric mucosal cells was detected by reverse transcription-polymerase chain reaction (RT-PCR) method. RESULTS: Compared with normal group (0.6860 ± 0.0594), the serum derived from rats of the stomach group (1.2272 ± 0.0813, P = 0.00 < 0.01) and gallbladder group (0.9640 ± 0.0387, P = 0.00 < 0.01) had a tendency to enhance the EGFR gene expression in gastric mucosal cells. Such tendency existed in the model group (0.7104 ± 0.0457) but with no signifi cant difference (P = 0.495 > 0.05) and in model serum group (0.8516 ± 0.0409) with an extremely obvious difference (P = 0.001 < 0.01). Furthermore, the EGFR gene expression in stomach serum group was significantly higher than that in gallbladder serum group (P = 0.00 < 0.01). CONCLUSION: The present study shows that serumderived from rats treated with electroacupuncture at stomach meridian acupoints can distinctly increase the EGFR gene expression of gastric mucosal cells. Therefore, there is certain meridian specificity in the serum, which could provide a proof for the TCM theory “particular relation between meridian and internal organ”.

Discussion on Prevention and Treatment of Lower Extremity Deep Venous Thrombosis in Orthopedic Perioperative Period from Spleen and Stomach Meridians

Deep venous thrombosis of lower extremity is one of the common complications in orthopedic perioperative period.It is caused by many factors,such as peripheral vein dilation,slow blood flow;long-term immobilization,bed rest and so on.On the one hand,it affects the early postoperative functional exercise and functional recovery,on the other hand,it increases the length of hospital stay and economic burden,increases the pain of patients and even endangers their lives.Effective treatment of traditional Chinese medicine combined with western medicine can play a better role in the prevention and treatment of lower extremity deep venous thrombosis.This study expounds the concept of spleen and stomach meridians in the prevention and treatment of lower extremity deep venous thrombosis,and puts forward some opinions on the dialectical treatment and daily conditioning of lower extremity deep venous thrombosis,hoping to provide ideas for the clinical prevention and treatment of lower extremity deep venous thrombosis in traditional Chinese medicine.

以循经理论为基础的刮痧联合五行音乐在肝胃气滞型胃络痛伴失眠中的应用

目的探讨以循经理论为基础的刮痧联合五行音乐在肝胃气滞型胃络痛伴失眠中的应用效果。方法选取河南省中医院2021年1月—2022年6月收治106例肝胃气滞型胃络痛伴失眠患者,根据治疗方案分为观察组与对照组各53例。对照组给予常规治疗,观察组在对照组基础上给予以循经理论为基础的刮痧联合五行音乐治疗。比较两组治疗前后睡眠质量变化、疼痛症状变化、生活质量变化及疗效。结果治疗后,观察组匹兹堡睡眠质量指数量表(PSQI)中睡眠质量、睡眠时间、入睡时间、睡眠效率、睡眠障碍、睡眠药物、日间功能内容评分及PSQI总分均低于对照组(P<0.05)。观察组视觉模拟评分法(VAS)评分低于对照组低(P<0.05),健康调查简表(SF-36)评分高于对照组高(P<0.05)。观察组总有效率高于对照组(P<0.05)。结论以循经理论为基础的刮痧联合五行音乐治疗肝胃气滞型胃络痛伴失眠患者效果显著,能有效提升睡眠质量,减轻疼痛,进一步改善生活质量,值得推广。

陆氏健脾和胃针刺法治疗代谢综合征的随机对照研究

目的:观察陆氏健脾和胃针刺法治疗代谢综合征(MetS)的临床疗效。方法:选取2020年3月至2022年3月于上海市第七人民医院就诊的MetS患者90例作为研究对象,按照随机数字表法分为观察组和对照组,每组45例。对照组采用健康宣教及常规药物治疗,观察组在此基础上加用陆氏健脾和胃针刺法。比较2组患者治疗前后体质量、腰围、体质量指数(BMI)、血脂、血糖、血压的变化。结果:意向性治疗(ITT)分析结果显示,2组患者各时间点体质量、腰围及BMI均较治疗前显著降低(P<0.05),且观察组各时间点体质量、腰围及BMI显著低于对照组(P<0.05);2组患者治疗后血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)均较治疗前下降(P<0.05),高密度脂蛋白胆固醇(HDL-C)明显上升(P<0.05),治疗后观察组TC、TG、HDL-C变化幅度较对照组更显著(P<0.05);2组患者治疗后空腹血糖(FBG)、糖化血红蛋白(HbA1c)及胰岛素抵抗指数(HOMA-IR)均比治疗前降低(P<0.05),治疗后观察组FPG、HbA1c及HOMA-IR值均比对照组降低明显(P<0.05)。2组患者治疗前后血压指标无明显变化(P>0.05),针刺期待值与临床疗效无明显相关性(P>0.05)。结论:陆氏健脾和胃法针刺法能有效降低MetS患者的体质量、腰围、BMI,改善血脂、血糖水平,并且具有良好的远期疗效。

通调带脉治疗脾胃与妇科合病临证思路

现代医学中消化科疾病和妇科疾病分属不同学科,从中医整体观认知,脾胃与妇科合病可统称为带脉病。中医学认为,带脉病基本病因病机系湿热中阻蕴带、寒湿困脾阻带、火热灼带及精气血不足所致带脉虚陷,治疗主要采用通调带脉法,从带脉、脾、胃、肝及冲脉、任脉多经参详论治,是中医辨证论治的体现。通调带脉法包括清带脉湿热、温带脉寒湿、止带脉疼痛和固带脉虚脱。临证论治腹部症状包含脾胃和妇科疾病时,可斟酌考虑,灵活运用,化繁为简,异病同治。

腧穴歌诀记忆法在经络腧穴学教学的应用——以胃经为例

经络腧穴学是针灸推拿学专业的基础课和主干课。经络腧穴学中的腧穴数量繁多,一直以来都占据课堂教学的大部分时间,也是学生学习记忆的难点。针灸歌赋借用文学体例形式,融合针灸学内容,是针灸学的重要组成部分,是学习针灸和经络腧穴的重要载体之一。时过境迁,古代腧穴歌诀难以契合现代经络腧穴学教学要求。文章在现代经络腧穴学教学大纲指导下,结合古代腧穴歌诀,拟定一套覆盖十四经的腧穴歌诀。以胃经腧穴歌诀为例,阐述其在课堂教学中的具体应用,从而提高腧穴教学的近期与远期效果。

子午流注择时穴位贴敷联合加味温胆汤治疗肝胃不和型妊娠恶阻31例

目的 观察子午流注择时穴位贴敷联合加味温胆汤对肝胃不和型妊娠恶阻的疗效。方法 收集2021年1月~2023年11月在福建中医药大学附属第二人民医院产科住院的肝胃不和型妊娠恶阻62例进行回顾性分析,根据治疗方法不同分为单一补液组(A组)31例和在A组基础上进行子午流注择时穴位贴敷联合加味温胆汤组(B组)31例,对两组患者恶心呕吐(PUQE)评分、妊娠焦虑量表评分、尿酮体水平及转阴率、重返住院率等情况进行分析、总结。结果 治疗后,两组患者恶心呕吐(PUQE)评分、妊娠焦虑量表评分、尿酮体水平均低于治疗前(P<0.05);B组恶心呕吐(PUQE)评分、妊娠焦虑量表评分、尿酮体水平均低于A组且B组优于A组(P<0.05)。B组尿酮体转阴率54.84%,高于A组29.03%(P<0.05);B组重返住院率3.22%,低于A组22.58%(P<0.05)。结论 子午流注择时穴位贴敷联合加味温胆汤治疗能够改善患者恶心呕吐症状,减轻患者的妊娠焦虑状态,改善尿酮体水平,提高尿酮体转阴率,减少重返住院率,且操作简单方便,效果优于单一静脉补液。

全国名老中医药专家常小荣基于“经脉-脏腑相关”理论辨治脾胃病特色探骊

常小荣教授认为“经脉-脏腑相关”是经络学说的核心理论,对临床工作有重要指导意义。总结常小荣教授基于“经脉-脏腑相关”理论辨治脾胃病的学术经验,在临床诊治脾胃病过程中注重经脉辨证与脏腑辨证相结合,治则以调畅中焦、调和五脏气机为要,辨证严谨,选穴精准,以四白、梁门、足三里为治疗脾胃病的基础用穴,并注重灸法的运用。常小荣教授提倡学习经典与继承创新,坚持研究与临床相结合,为传承发展“经脉-脏腑相关”理论作出了重大贡献。

和胃针法治疗失眠理论探析

[目的]总结马睿杰教授运用和胃针法治疗失眠的临床经验,阐释和胃针法治疗失眠的理论依据及临床应用思路。[方法]通过临床跟师学习,并查阅中医典籍和现代医学对失眠的临床研究文献,从马睿杰教授对失眠的病因病机认识、和胃针法的组成及取穴依据、和胃针法治疗失眠的理论及机制研究等方面进行阐述,分析马睿杰教授对本病的辨治思路。[结果]马睿杰教授认为,人之寤寐由心神主导,依靠营卫阴阳调节,与脏腑功能相关,其中脾胃功能的失常与失眠的发生密切相关。治疗本病,重视经络病候理论和中焦脾胃气机,认为足阳明胃经经气逆乱、营卫失和,脾胃亏虚、心神失养,升降失常、斡旋失司是失眠发生的重要原因。和胃针法是马睿杰教授以天枢、足三里、内关、公孙为主穴治疗失眠等神经系统疾病的临床经验总结,此针法通过调畅脾胃气机、健运脾胃功能、平衡机体阴阳等改善失眠。[结论]和胃针法在失眠的临床治疗中具有取穴精简、疼痛感轻、远期疗效好的特点,对于指导临床治疗失眠具有切实意义。

“枢机”探析

“枢机”最早起源于北斗七星之天枢,门户枢是其形象化的表现。在《黄帝内经》中应用有三,一是指关节,二是指穴位,三是指三阴三阳“开阖枢”理论。后者被运用到《伤寒论》六经辨证中,其中少阳枢机历代医家关注最多。后世医家在实践中丰富了“枢机”内涵,提出了脾胃枢机、玄府枢机、卫气营血枢机、三焦枢机、膜原枢机、脏腑枢机、枢经学说等,并在枢机病变的治疗中提出了枢机之剂,对枢机病变治疗的方药进行初步总结。枢机不仅是阴阳表里、寒热内外、上下气血出入的通道,更是正气与邪气斗争进出的场所,是疾病转归的关键。枢机宜调、宜和,在扶正的同时祛邪,给邪气以出路。调枢的过程可能会伴随瞑眩反应,临床需注意鉴别。

基于《灵枢·营卫生会》解读“六经病欲解时”和六经病

《灵枢·营卫生会》言:“卫气行于阴二十五度,行于阳二十五度,分为昼夜……如是无已,与天地同纪。”荣卫二气于阴分、阳分各行二十五周,对应昼夜。太阳病欲解时,卫气运行到日中重阳,胃气相对较强,卫气行而盛于外,荣气相对充足。阳明病欲解时,阳尽而阴受气,卫气盛于荣气。少阳病欲解时,阳气从里出表,荣卫二气较弱。太阴病欲解时为重阴,胃气虚衰,荣卫二气生成不足。少阴病欲解时为阴衰,胃气弱,卫气衰,荣气弱。厥阴病欲解时,阴尽而阳受气,此时胃气弱致荣卫生成不足,但同时有卫气初出的趋势。治疗在于维持胃气的正常运行及荣卫二气的平衡,太阳病当泻卫固荣,方选麻黄汤类方;阳明病当清卫补荣,方选承气汤、白虎汤类方;少阳病当补荣疏卫,方选柴胡类方;太阴病当补荣和卫,方选桂枝汤类方;少阴病当补卫固胃护荣,方选四逆汤类方;厥阴病当护胃存荣固卫,方选乌梅丸、干姜黄芩黄连人参汤等方。

针刺足阳明胃经经穴治疗不完全性脊髓损伤功能障碍临床疗效研究

目的:探究针刺足阳明胃经经穴治疗不完全性脊髓损伤功能障碍的临床疗效。方法:选取2020年4月—2022年4月收治的78例不完全性脊髓损伤功能障碍患者,按照随机数字表法分为对照组和观察组,每组39例。对照组患者采用常规药物治疗和康复训练,观察组在对照组的基础上联合针刺足阳明胃经经穴(天枢、梁丘、丰隆、上巨虚)治疗,比较治疗后两组治疗总有效率、脊髓损伤评定量表(ASIA)神经功能评定(运动、感觉)。脊髓独立性(SCIM-Ⅲ)、膀胱功能(排尿次数、日最大排尿量)、肺功能[用力肺活量(FVC)、第1秒用力呼气量(FEV1)]及生活质量水平[明尼苏达生活质量表(MLHFO)评分]。结果:观察组总有效率明显高于对照组,差异具有统计学意义(P<0.05)。治疗后,两组ASIA运动评估MS、感觉指数SIS评分明显上升(P<0.05),且观察组评分较对照组上升更明显(P<0.05)。治疗后,两组SCIM-Ⅲ评分均明显提高(P<0.05),且观察组SCIM-Ⅲ评分明显高于对照组(P<0.05)。治疗后,两组排尿次数均下降(P<0.05),且观察组明显低于对照组(P<0.05),日最大排尿量明显增多,且观察组改善程度明显优于对照组(P<0.05)。治疗后,两组FVC、FEV1值均明显提高(P<0.05),且观察组FVC、FEV1值明显高于对照组(P<0.01)。治疗后,两组生活质量水平改善明显,且观察组明显优于对照组(P<0.05)。结论:常规治疗联合针刺足阳明胃经经穴能有效治疗不完全性脊髓损伤功能障碍,可明显减轻患者临床症状、缓解患者痛苦。

胃经和心包经穴位对多器官功能调节的实验观察

目的 :观察和比较心包经和胃经对胃和心脏机能的调节。方法 :用药物 (盐酸消旋山莨菪碱)制作胃和心脏机能偏态的背景。分别针刺分属心包经的 3个穴位和胃经的 4个穴位 ,同步观察针刺后心脏和胃的机能变化 ,比较不同穴位针刺后的调节效应。结果 :(1 )心包经和胃经的不同穴位针刺效应基本一致。 (2 )各个穴位刺后基本完全克服药物对胃电节律的影响。(3)各个穴位针刺后可部分消除药物对胃电波幅和心率的影响。结论 :(1 )胃经和心包经的穴位对胃和心脏的调节无明显差异。 (2 )

针刺足阳明经穴对兔胃粘膜损伤前后胃运动功能的影响

目的 :探讨足阳明经与胃的相关规律。方法 :对 4 0只大耳白兔用无水乙醇灌胃 ,造成胃粘膜损伤模型 ,然后观察针刺对胃粘膜损伤前后胃运动功能的影响。 结果 :胃粘膜损伤造模后 ,胃运动振幅指数显著下降 (P <0 0 1) ,针刺“四白”、“足三里”穴能增强胃运动 ,针后比针前胃运动振幅指数显著升高 (P <0 0 1)。结论 :针刺足阳明经穴后可使胃运动振幅指数上升 ,提示足阳明经与胃具有相关性。

Effect of electroacupunture on gastric mucosal intestinal trefoil factor gene expression of stress-induced gastric mucosal injury in rats

AIM： To investigate electroacupunture（EA） at the acupoints of Stomach Meridian of Foot-Yangming（SMFY）, Gallbladder Meridian of Foot-Yangming（SMFY） on gastric mucosal intestinal trefoil factor （ITF） gene expression detection in stress-induced rats with gastric mucosal lesion, and to explore the regulatory mechanism and significance of EA-related gastric mucosal protective effect. METHODS： Forty rats were randomly divided into 4 groups： Blank group, Model group, Model group＋EA at acupoints of SMFY group（＂SMFY group＂）, and Model group＋EA at acupoints of GMFY group（GMFY group）. All rats （except blank group） were made model by water immersion and restraint stress （WRS）. Then the gastric mucosa tissue in each rat was taken off alter assessment of gastric mucosal lesion index（GUI）, and the expression of ITF mRNA of the tissues was detected by reverse transcdption-polymerase chain reaction（RT-PCR） method. RESULTS： Compared with Model group（S4.3± 1.34）, the GUI value in SMFY group （31±2.211 decreased significantly（P〈0.01）, so did that in GMFY group （39.8± 1.62, P〈0.05）, meanwhile GUI value in SMFY group was significantly lower than in GMFY group（P〈0.01）. Compared with Model group （0.65±0.01）, EA had a tendency to improve the expression of gastric mucosal ITFmRNA gene： such tendency existed in GMFY group （0.66±0.01） but with no signficant difference（P〉 0.05）, in SMFY group（0.76±0.01） with an extremely obvious difference （P〈0.01）, furthermore the expression in SMFY group was significantly higher than in GMFY group （P〈 0.01）.CONCLUSION： The gastric mucosal protective effect by EA at the acupoints of SMFY and GMFY was related to the expression variance of ITF, indicating certain meridian specificity exists, It could be one proof for the TCM theory ＂Relative pardcularity between SMFY and stomach＂.

核素循经迁移路线在实体结构上的初步定位

目的:观察穴位注入核素后在具体实体结构上的循经迁移路线。方法:将131I分别注入大鼠“后三里”、“关元”腧穴,分别切取大鼠胃经和任脉沿线向心方向的脂肪条带结构、或其两侧肌组织及与之相对应的皮肤,进行放射自显影。结果:只有131I注射侧的胃经及任脉沿线脂肪条带结构上才显现出核素循行的轨迹。结论:经脉沿线脂肪条带结构与经脉线似具有重要相关性。

小型猪胃经与肾经经脉不通病理模型的比较观察

目的:为小型猪"经脉不通"病理模型的研究提供科学依据,比较不同经脉异常所引起的病候差异。方法:将19只小型猪随机分为胃经不通组(7只)、肾经不通组(7只)和对照组(5只),用凝胶注射法分别堵塞胃经和肾经低流阻通道,对照组只作麻醉处理,饲养7~9周观察相关指标。结果:胃经组的饮水量与尿量均显著高于其他2组,粪便含水率极显著低于肾经组,腰围体躯指数显著高于对照组。肾经组的饮水量与尿量极显著低于胃经组,粪便含水率极显著高于胃经组,第1门齿长度极显著大于其他2组。结论:凝胶堵塞胃经和肾经低流阻通道后,小型猪可分别出现与胃经-胃腑和肾经-泌尿生殖系统特异相关的病候,证明经脉不通是导致相关经脉病候的病理机制之一,且存在经脉的差异。

胃络瘀血型慢性萎缩性胃炎患者胃经穴位电阻测试分析

目的测试并分析胃络瘀血型慢性萎缩性胃炎患者胃经穴位的电阻,总结疾病状态下胃经的虚实状况,以指导针灸临床治疗。方法共收集51例胃络瘀血型慢性萎缩性胃炎患者,应用体表电阻测量法测定双侧胃经厉兑、内庭、陷谷、冲阳、解溪、丰隆、足三里、梁丘诸穴电阻,对结果进行统计分析。结果冲阳穴电阻显著低于其他穴位,梁丘穴电阻显著高于其他穴位,差异具有统计学意义(P<0.01)。结论胃络瘀血型慢性萎缩性胃炎患者胃经穴位电阻值不同,体现了胃经诸穴的不同虚实状况和本病脾胃虚弱为本、气滞血瘀为标的基本病机,可以有效地指导针灸临床治疗。