Photodynamic patterning of living bacterial biofilms with high resolutions for information encryption and antibiotic screening

Controlling the growth of bacterial biofilms in a specific pattern greatly enhances the study of cell-to-cell interactions and paves the way for expanding their biolog-ical applications.However,the development of simple,cost-effective,and highly resolved biopatterning approaches remains a persistent challenge.Herein,a pio-neering photodynamic biopatterning technique for the creation of living bacterial biofilms with customized geometries at high resolutions is presented.First of all,an outstanding aggregation-induced emission photosensitizer is synthesized to enable efficient photodynamic bacterial killing at a low concentration.By combining with custom-designed photomasks featuring both opaque and transparent patterns,the viability of photosensitizer-coated bacteria is successfully manipulated by control-ling the degree of light transmittance.This process leads to the formation of living bacterial biofilms with specific patterns replicated from the photomask.Such an innovative strategy can be employed to generate living bacterial biofilms composed of either mono-or multispecies,with a spatial resolution of approximately 24µm.Furthermore,its potential applications in information storage/encryption and antibi-otic screening are explored.This study provides an alternative way to understand and investigate the intricate interactions among bacteria within 3D biofilms,hold-ing great promise in the controlled fabrication of dynamic biological systems for advanced applications.

Magneto-optical Disk Material for Improving the Density of Information Storage

This paper introduces the fundamental principle and features ofmagneto-optical storage technol- ogy, and discuses the trend and aseries of key techniques for increasing the data storage density ofmagneto-opti- cal disk. The three ways including MO media, recordingmethod and readout method for increasing the disk ca- pacity havebeen discussed. Moreover, the importance with the exchange-coupledeffect between the magnetic layers and recording domain morphology isemphasized.

Multicolor Circularly Polarized Luminescence of a Single-Component System Revealing Multiple Information Encryption

Metal-free materials with multicolor tunable circularly polarized luminescence(CPL)are attractive because of their potential applications in information storage and encryption.Here,we designed two enantiomers composed of chiral dialkyl glutamides and achiral vibration-induced emission(VIE)moiety,which can switch on CPL after a simple gelation process.It is noteworthy that the CPL colors vary in different solvents,and this is attributed to various self-assembly-induced microstructures,in which the VIE moiety is restrained to different degrees.Accordingly,a multidimensional code system composed of a quick response code,a ultraviolet(UV)light-activated color code,and a CPL information figure was constructed.To our satisfaction,the system possesses multiple information-storage functions.The orthogonal anticounterfeiting and CPLenhanced encryption functions also improve the system information encryption ability.In brief,this study provides a practical example of CPL applied to information security and an effective approach to obtain a single-component color-tunable CPL material with multiple information storage and encryption functions as well.

Gd_(3)Al_(3)Ga_(2)O_(12):Ce^(3+), Yb^(3+) fluorescent ceramic with highly increased trap density for optical information storage

Electron-trapping materials,due to their exceptional ability of energy storage and controllable photon release under external stimulation,have attracted considerable attention in the field of optical information storage(OIS).In this work,Gd_(3)Al_(3)Ga_(2)O_(12):Ce^(3+), Yb^(3+)fluorescent ceramics,were developed using air and vacuum sintering technology.By co-doping Ce^(3+)and Yb^(3+),the trap density was significantly increased by 7.5 times compared to samples containing only Ce^(3+).Vacuum annealing further enhanced trap density by 1.6 times compared to samples sintered solely in air,while generating deep traps(1.44 eV),making Gd_(3)Al_(3)Ga_(2)O_(12):Ce^(3+), Yb^(3+) an excellent OIS medium.This work is expected to facilitate the development of OIS materials.

Holographic storage of three-dimensional image and data using photopolymer and polymer dispersed liquid crystal films

We present holographic storage of three-dimensional（3D） images and data in a photopolymer film without any applied electric field.Its absorption and diffraction efficiency are measured,and reflective analog hologram of real object and image of digital information are recorded in the films.The photopolymer is compared with polymer dispersed liquid crystals as holographic materials.Besides holographic diffraction efficiency of the former is little lower than that of the latter,this work demonstrates that the photopolymer is more suitable for analog hologram and big data permanent storage because of its high definition and no need of high voltage electric field.Therefore,our study proposes a potential holographic storage material to apply in large size static 3D holographic displays,including analog hologram displays,digital hologram prints,and holographic disks.

Charge Qubit Storage and Its Engineered Decoherence via Microwave Cavity

We study the entanglement of the superconducting charge qubit with the quantized electromagnetic field in a microwave cavity. It can be controlled dynamically by a classical external field threading the SQUID within the charge qubit. Utilizing the controllable quantum entanglement, we can demonstrate the dynamic process of the quantum storage of information carried by charge qubit. On the other hand, based on this engineered quantum entanglement, we can also demonstrate a progressive decoherence of charge cubit with quantum jump due to the coupling with the cavity field in quasi-classical state.

Self-erasable dynamic surface patterns via controllable elastic modulus boosting multi-encoded and tamper-proof information storage

Dynamic surface patterns(DSPs)have attracted significant interest in anti-counterfeiting,enabling information to be stored,encrypted and decrypted in response to external stimuli.However,creating dynamic surface patterns,capable of controlling wrinkling time and independently modulating different information in both wrinkled and fluorescent states,remains a tremendous challenge.These limit DSPs to further enhance tamper-proofing capacity and extend the information storage density.Here,a rationally designed patterning strategy based on controllable elastic modulus was demonstrated to fabricate self-erasable dynamic surface patterns(S-DSPs)that increase information storage density.These novel S-DSPs strategically integrated amino co-oligomers(ACOs)with the 9-anthracenemethanol(9-AM)as skin layers,designing a bilayer multi-encoding system which could carry several different types of information with wrinkled and fluorescent patterns.The ACOs with relatively low molecular weight can endow the elastic modulus of skin layers with a wide range of regulation.As a result,the difference between the compressive strain and the critical wrinkle strain in the bilayer system would be precisely modulated by photo-dimerization to form quick-response(minimum<1 min)and self-erasable(3 min–8 days)wrinkled patterns for S-DSPs.Meanwhile,the fluorescence pattern could be independently erased and reprogrammed without affecting the change in the wrinkle pattern under modulus-controlled conditions.Moreover,controllable self-erasure in S-DSPs significantly develops tamper-proof capabilities in a supply chain.This original strategy could provide a new approach to the tamper-proof,high-density,and multi-encoded information storage in the product security or inkless printing.

Light-Responsive Polyblend Films with Reconfigurable Surface Micropatterns as Rewritable Information Storage Media

Stimulus-sensitive surfaces with tunable morphologies exhibit a wide range of applications in the fields of surface science and engineering.Herein,a cost-effective yet practical strategy is proposed to fabricate photo-sensitive patterning surface on film/substrate wrinkle system based on an azo-containing polyblend.By manipulating the stress field of the bilayer system globally and/or locally upon the stress relaxation triggered by the reversible cis-trans isomerization of the azobenzene,heating/cooling triggered surface wrinkles on the polyblend films could be tailor-made with visible-light-irradiation.Notably,upon selective photo-irradiation,bespoke surface patterns may be cyclically generated or eliminated,allowing these reconfigurable patterned polyblend surfaces to be used as rewritable information storage media for non-ink printing.The as-prepared photo-printed information patterns with high-resolution are shown to be rewritable for multiple cycles and legible for over 90 d in dark ambient conditions.This study not only provides a versatile strategy for flourishing the stimulus-sensitive systems,but also sheds light on the stress relaxation-triggered morphological evolution of the wrinkling polyblend films.

Borophene-based materials for energy,sensors and information storage applications

Borophene,as a rising-star monoelemental two-dimensional(2D)material,has motivated great interest because of its novel properties,such as anisotropic plasmonics,high carrier mobility,mechanical compliance,optical transparency,ultrahigh thermal conductance,and superconductivity.These properties make it an ideal candidate for use in the field of energy,sensors,and information storage.Stimulated by the realization of pioneering experimental works in 2015 and the follow-up synthesis experiments,a series of high-performance borophene-based devices in the fields,including supercapacitors,batteries,hydroelectric generators,humidity sensors,gas sensors,pressure sensors,and memories,have been experimentally reported in recent years,which are beneficial to the transition of borophene-based materials from experimental synthesis to practical application.Therefore,in addition to paying attention to the experimental preparation of borophene,significant efforts are needed to promote the advancement of related applications of borophene.In this review,after providing a brief overview of borophene evolution and synthesis,we mainly summarize the applications of borophene-based materials in energy storage,energy conversion,energy harvesting,sensors,and information storage.Finally,based on the current research status,some rational suggestions and discussions on the issues and challenges in the future research direction are proposed.

Ionoprinting controlled information storage of fluorescent hydrogel for hierarchical and multi-dimensional decryption

Information storage and corresponding encryption/decryption are highly important owing to the prevalence of counterfeit activities and information leakage in the current age. Herein, we propose a novel method to store information via controllable ionoprinting onto fluorescent hydrogel for hierarchical and multi-dimensional decryption.Through incorporating pyrene moieties and carboxylic groups into polymeric hydrogel network, fluorescence changing and controllable shape deformation behaviors could be achieved and integrated by ionoprinting of Fe3+ions. The diffusion of Fe^3+ions into fluorescent hydrogel can quench the fluorescence of pyrene moieties, and chelate with carboxylic groups to generate anisotropic structures for shape deformation simultaneously. Thus, fluorescence quenching-based 2D information and actuation-based 3D information could be hierarchically decrypted when exposed to UV light and being put into water, respectively. Importantly, the stored information could be erased by replacing Fe^3+with H^+, which allows the fluorescent hydrogel as a recyclable information storage material. This work may provide new insights in designing and fabricating novel soft devices for hierarchical and multidimensional information encryption, against the rising problems of counterfeiting and confidential information disclosure.

Organic photoresponsive materials for information storage:a review

Organic photoresponsive materials can undergo various reversible variations in certain physical and chemical properties,such as optical properties,electrochemical properties,conformation,and conductivity,upon photoirradiation.They have been widely applied in various optoelectronic fields,especially in information storage.We summarize research progress on organic photoresponsive materials for information storage.First,the design strategies and photoswitching mechanisms for various kinds of organic photoresponsive materials,including small organic molecules,metal complexes,polymers,supramolecules,and cholesteric liquid crystals,are systematically summarized.These materials exhibit reversible changes of absorption and/or emission properties in response to different wavelengths of light.Subsequently,the applications of these organic materials in information storage,such as data(re)writing and erasing,encryption and decryption,and anticounterfeiting,are introduced in detail.Finally,the current challenges and future directions in this rapidly growing research field are discussed.The review will provide important guidance on the future works about the design of excellent organic photoresponsive materials for optoelectronic applications.

A mirror-image protein-based information barcoding and storage technology

A mirror-image protein-based information barcoding and storage technology wherein D-amino acids are used to encode information into mirror-image proteins that are chemically synthesized is described.These mirror-image proteins were then fused into various materials from which information-encoded objects were produced.Subsequently,the mirror-image proteins were extracted from the objects using biotin-streptavidin resin-mediated specific enrichment and cleaved using an Ni(Ⅱ)-mediated selective peptide cleavage.Protein sequencing was accomplished using liquid chromatography/tandem mass spectrometry(LC-MS/MS)and then transcoded into the recorded information.We demonstrated the use of this technology to encode Chinese words into mirror-image proteins,which were then fused onto a poly(ethylene terephthalate)(PET)film and retrieved and decoded by LC-MS/MS sequencing.Compared to information barcoding and storage technologies using natural biopolymers,the mirrorimage biopolymers used in our technology may be more stable and durable.

Screening Effect in Charge Qubit

We study the influence of screening effect on quantum decoherence for charge qubit and the process of quantum information storage. When the flux produced by the circulating current in SQUID loop is considered, screening effect is formally characterized by a LC resonator. Using large-detuning condition and Fr6hlich transformation in the qubit-cavity-resonator system, we calculate the decoherenee factor for charge qubit and the effective qubit-cavity Hamiltonian. The decoherence factor owns a factorized structure, it shows that screening effect is a resource of decoherence for charge qubit. The effective Hamiltonian shows that the screening effect results in a frequency shift for charge qubit and a modified qubit-cavity coupling constant induced by a LC resonator.

基于温度开关的光响应智能水凝胶用于可逆信息加密和解密

在智能凝胶防伪系统中使用的光、热、电、pH等刺激响应性水凝胶,是一种有前途的信息加密和解密材料.然而单一刺激会限制高水平的防伪.因此,需要协同使用多种刺激来提升信息安全等级.本研究设计了一种高透明度的海藻酸钠-聚丙烯酰胺(SA-PAM)水凝胶作为基体,利用无机变色材料钼酸铵(Mo7)赋予其凝胶光致变色特性.此外,温敏材料聚N-异丙基丙烯酰胺(PNIPAM)可使凝胶在最低临界相变温度(LCST)下发生体积相变,进而改变凝胶的宏观状态,可以通过调整凝胶体系中亲水单体和疏水单体的比例来控制LCST.利用紫外线(UV)作为“墨水”输入信息,以温度作为“开关”来加密/解密信息.总之,该水凝胶具有出色的光致变色能力,可在10 s内着色,紫外光吸收率最高可达96.23%.利用水凝胶对光-热刺激展现出的非凡响应能力,可以实现其迅速显示和隐藏信息的功能,从而确保信息安全,这为光致变色水凝胶在信息加密领域的应用提供了一种新方法.

Ultraviolet-activated long-lived room-temperature phosphorescence from small organic molecule-doped polymer systems

Long-lived organic room-temperature phosphorescent(RTP)materials have attracted widespread attention because of their fantastic properties and application prospects.The current methods for developing RTP materials are mainly based on the synthesis of new chromophore molecules and crystallization engineering.However,there are great challenges in the preparation of new chromophore molecules and the use of crystalline materials.Herein,dynamic stimulus-responsive long-lived RTP systems with various emission colors are realized by doping organic chromophore molecules into polymer matrix prepared from vinyl acetate and acrylic acid.Through UV light irradiation,the growth process of long-lived RTP phenomena can be observed for up to 10 s.In particular,the phosphorescence intensity,lifetime,afterglow brightness,and quantum yield of one representative film(P2-M2)increase by 155,262,414,and 8 times after the irradiation,respectively.The unique photophysical phenomena are ascribed to the oxygen consumption characteristics of the polymer matrix under UV irradiation.Meanwhile,the information storage devices are prepared with these RTP systems.This work provides a strategy for achieving small organic molecule-doped polymer RTP systems that are easy to prepare,low-cost,and widely adaptable.

Query Performance Prediction for Information Retrieval Based on Covering Topic Score

We present a statistical method called Covering Topic Score （CTS） to predict query performance for information retrieval. Estimation is based on how well the topic of a user＇s query is covered by documents retrieved from a certain retrieval system. Our approach is conceptually simple and intuitive, and can be easily extended to incorporate features beyond bag- of-words such as phrases and proximity of terms. Experiments demonstrate that CTS significantly correlates with query performance in a variety of TREC test collections, and in particular CTS gains more prediction power benefiting from features of phrases and proximity of terms. We compare CTS with previous state-of-the-art methods for query performance prediction including clarity score and robustness score. Our experimental results show that CTS consistently performs better than, or at least as well as, these other methods. In addition to its high effectiveness, CTS is also shown to have very low computational complexity, meaning that it can be practical for real applications.

Sustainable curcumin-based smart tough fluorescent hydrogels for anti-counterfeiting applications

There is currently great interest in developing an environment-friendly,low-cost,and scalable approach for producing stimuli-responsive fluorescent hydrogels(FHs)with excellent mechanical property,rewritable fluorescence,and dual anti-counterfeiting capabilities.Herein,by applying natural,environment-friendly,and sustainable curcumin as a responsive agent,tough pH-responsive FHs(pH-FHs)are fabricated via a facile preparation strategy.These materials have outstanding mechanical performances:ultimate stress of 180 kPa,an ultimate strain of~2500%,and good anti-fatigue performances against compression.These pH-FHs are able to sense ammonia and formaldehyde gas,resulting in both a color change and fluorescence for dual anti-counterfeiting functionality.This sensing information is stored individually by the pH-FHs and could be externally removed using formaldehyde gas to achieve a rewritable system.Our study provides valuable insights that are expected to facilitate the development of smart FHs for information encryption and anti-counterfeiting applications.

Large area patterning of ultra-high thermal-stable structural colors in transparent solids

Printing stable color with a lithography-free and environment-friendly technique is in high demand for applications.We report a facile strategy of ultrafast laser direct writing(ULDW)to produce large-scale embedded structural colors inside transparent solids.The diffraction effect of gratings enables effective generation of structural colors across the entire visible spectrum.The structural colors inside the fused silica glass have been demonstrated to exhibit excellent thermal stability under high temperature up to 1200℃, which promises that the written information can be stable for long time even with unlimited lifetime at room temperature.The structural colors in the applications of coloring,anti-counterfeiting,and information storage are also demonstrated.Our studies indicate that the presented ULDW allows for fabricating large-scale and high thermal-stability structural colors with prospects of three-dimensional patterning,which will find various applications,especially under harsh conditions such as high temperature.

Literature-based analysis on relationship of symptoms,drugs and therapies in treatment of intestinal diseases

OBJECTIVE:To evaluate clinical articles published in the past 30 years using the Traditional Chinese Medicine(TCM)theory of the lung being connected with large intestine to treat intestinal diseases.We also analyzed the relationship between symptoms,drugs and therapies with data-excavating technology to aid management.METHODS:After retrieving relevant clinical articles,we set up a database,used Microsoft Structured Query Language Server 2005 Analysis Services as a data-excavating tool,and applied the association rule to study the relationship between the symptoms,drugs and therapies of intestinal diseases.RESULTS:The key symptoms of dyschesia,constipation,abdominal fullness,fatigue and pale tongue could be treated with Kuxingren(Semen Armeniacae Amarum),Huangqi(Radix Astragali Mongolici)and Gualou(Fructus et Semen Trichosanthis)to invigorate Qi and moisten the intestine.Among these agents,Kuxingren(Semen Armeniacae Amarum)was used most frequently.Clearing Fu-organs was the most prevalent therapy for abdominal fullness,dyschesia,constipation and red tongue.Clearing Fu-organs could be achieved with Kuxingren(Semen Armeniacae Amarum)and Gualou(Fructus et Semen Trichosanthis),whereas Qi could be invigorated using Huangqi(Radix Astragali Mongolici),Gancao(Radix Glycyrrhizae),Baizhu(Rhizoma Atractylodis Macrocephalae)and Kuxingren(Semen Armeniacae Amarum).Moistening the intestine was possible with Kuxingren(SemenArmeniacae Amarum),Huomaren(Fructus Cannabis)and Jiegeng(Radix Platycodi).Also,moistening the lungs was done with Kuxingren(Semen Armeniacae Amarum),ventilating the lungs with Kuxingren(Semen Armeniacae Amarum)and Gualou(Fructus et Semen Trichosanthis),and nourishing the lungs with Huangqi(Radix Astragali Mongolici),Gancao(Radix Glycyrrhizae)and Kuxingren(Semen Armeniacae Amarum).These data demonstrated that Kuxingren(SemenArmeniacaeAmarum)was a key agent.CONCLUSION:Our analyses of the literature showed clear relationships between symptoms(constipation,dyschesia,abdominal fullness),drugs[Gualou(Fructus et Semen Trichosanthis),Kuxingren(Semen Armeniacae Amarum),Huangqi(Radix Astragali Mongolici)]and therapies(moistening the intestine,clearing Fu-organs,invigorating Qi,ventilating the lungs).

Learning to detect subway arrivals for passengers on a train

The use of traditional positioning technologies, such as GPS and wireless local positioning, rely on un- derlying infrastructure. However, in a subway environment, such positioning systems are not available for the position- ing tasks, such as the detection of the train arrivals for the passengers in the train. An alternative approach is to exploit the contextual information available in the mobile devices of subway riders to detect train arrivals. To this end, we pro- pose to exploit multiple contextual features extracted from the mobile devices of subway riders to precisely detecting train arrivals. Following this line, we first investigate poten- tial contextual features which may be effective to detect train arrivals according to the observations from 3D accelerome- ters and GSM radio. Furthermore, we propose to explore the maximum entropy （MaxEnt） model for training a train ar- rival detector by learning the correlation between contextual features and train arrivals. Finally, we perform extensive ex- periments on several real-world data sets collected from two major subway lines in the Beijing subway system. Experi- mental results validate both the effectiveness and efficiency of the proposed approach.