“Hepatic hilum area priority,liver posterior first”:An optimized strategy in laparoscopic resection for type Ⅲ-Ⅳ hilar cholangiocarcinoma

BACKGROUND In recent years,pure laparoscopic radical surgery for Bismuth-Corlette type Ⅲ and Ⅳ hilar cholangiocarcinoma(HCCA)has been preliminarily explored and applied,but the surgical strategy and safety are still worthy of further improvement and attention.AIM To summarize and share the application experience of the emerging strategy of“hepatic hilum area dissection priority,liver posterior separation first”in pure laparoscopic radical resection for patients with HCCA of Bismuth-Corlette types Ⅲ and IV.METHODS The clinical data and surgical videos of 6 patients with HCCA of Bismuth-Corlette types Ⅲ and Ⅳ who underwent pure laparoscopic radical resection in our department from December 2021 to December 2023 were retrospectively analyzed.RESULTS Among the 6 patients,4 were males and 2 were females.The average age was 62.2±11.0 years,and the median body mass index was 20.7(19.2-24.1)kg/m^(2).The preoperative median total bilirubin was 57.7(16.0-155.7)μmol/L.One patient had Bismuth-Corlette type Ⅲa,4 patients had Bismuth-Corlette type Ⅲb,and 1 patient had Bismuth-Corlette type Ⅳ.All patients successfully underwent pure laparoscopic radical resection following the strategy of“hepatic hilum area dissection priority,liver posterior separation first”.The operation time was 358.3±85.0 minutes,and the intraoperative blood loss volume was 195.0±108.4 mL.None of the patients received blood transfusions during the perioperative period.The median length of stay was 8.3(7.0-10.0)days.Mild bile leakage occurred in 2 patients,and all patients were discharged without serious surgery-related complications.CONCLUSION The emerging strategy of“hepatic hilum area dissection priority,liver posterior separation first”is safe and feasible in pure laparoscopic radical surgery for patients with HCCA of Bismuth-Corlette types Ⅲ and Ⅳ.This strategy is helpful for promoting the modularization and process of pure laparoscopic radical surgery for complicated HCCA,shortens the learning curve,and is worthy of further clinical application.

Exploration of Innovation Strategy in the Deep Integration of Information Technology and Education and Teaching

The rapid development of information technology provides a new opportunity and impetus for the reform of education and teaching.Deep integration of information technology and education and teaching is the only way to promote the modernization of education.Starting from the connotation of the deep integration of information technology and education and teaching,this paper analyzes the existing problems in the current integration process,and puts forward innovative strategies from the aspects of concept,resources,model,and evaluation.Through measures such as building a smart teaching environment,enriching high-quality teaching resources,innovating teaching organization models,and establishing multiple evaluation systems,we will realize the deep integration of information technology and teaching,promote the reform of teaching and learning methods,improve the quality of personnel training,and provide strong support for the modernization of education.

Research on Enterprise Human Resource Management Reform Strategy in the Era of Big Data

In the 21st century,with the development of the Internet,mobile devices,and information technology,society has entered a new era:the era of big data.With the help of big data technology,enterprises can obtain massive market and consumer data,realize in-depth analysis of business and market,and enable enterprises to have a deeper understanding of consumer needs,preferences,and behaviors.At the same time,big data technology can also help enterprises carry out human resource management innovation and improve the performance and competitiveness of enterprises.Of course,from another perspective,enterprises in this era are also facing severe challenges.In the face of massive data processing and analysis,it requires superb data processing and analysis capabilities.Secondly,enterprises need to reconstruct their management system to adapt to the changes in the era of big data.Enterprises must treat data as assets and establish a perfect data management system.In addition,enterprises also need to pay attention to protecting customer privacy and data security to avoid data leakage and abuse.In this context,this paper will explore the thinking of enterprise human resource management innovation in the era of big data,and put forward some suggestions on enterprise human resource management innovation.

Origin of Bismuth-Rich Strategy in Bismuth Oxyhalide Photocatalysts

Recently,the bismuth-rich strategy via increasing the bismuth content has been becoming one of the most appealing approaches to improve the photocatalytic performance of bismuth oxyhalides.However,insights into the mechanism behind the encouraging experiments are missing.Herein,we report the results of the theory-led comprehensive picture of bismuth-rich strategy in bismuth oxyhalide photocatalysts,selecting Bi_(5)O_(7)X(X=F,Cl,Br,I)as a prototype.First-principle calculations revealed that the strategy enables good n-type conductivity,large intrinsic internal electric field,high photoreduction ability and outstanding harvest of visible light,and particularly ranked the intrinsic activity of this family:Bi_(5)O_(7)F>Bi_(5)O_(7)I>Bi_(5)O_(7)Br>Bi_(5)O_(7)Cl.Designed experiments confirmed the theoretical predictions,and together,these results are expected to aid future development of advanced photocatalysts.

“Parenchyma transection-first”strategy is superior to“tunnel-first”strategy in robotic spleen-preserving distal pancreatectomy with conservation of splenic vessels

Background: Creating a tunnel between the pancreas and splenic vessels followed by pancreatic parenchyma transection(“tunnel-first” strategy) has long been used in spleen-preserving distal pancreatectomy(SPDP) with splenic vessel preservation(Kimura’s procedure). However, the operation space is limited in the tunnel, leading to the risks of bleeding and difficulties in suturing. We adopted the pancreatic “parenchyma transection-first” strategy to optimize Kimura’s procedure. Methods: The clinical data of consecutive patients who underwent robotic SPDP with Kimura’s procedure between January 2017 and September 2022 at our center were retrieved. The cohort was classified into a “parenchyma transection-first” strategy(P-F) group and a “tunnel-first” strategy(T-F) group and analyzed. Results: A total of 91 patients were enrolled in this cohort, with 49 in the T-F group and 42 in the P-F group. Compared with the T-F group, the P-F group had significantly shorter operative time(146.1 ± 39.2 min vs. 174.9 ± 46.6 min, P < 0.01) and lower estimated blood loss [40.0(20.0–55.0) m L vs. 50.0(20.0–100.0) m L, P = 0.03]. Failure of splenic vessel preservation occurred in 10.2% patients in the TF group and 2.4% in the P-F group( P = 0.14). The grade 3/4 complications were similar between the two groups( P = 0.57). No differences in postoperative pancreatic fistula, abdominal infection or hemorrhage were observed between the two groups. Conclusions: The pancreatic “parenchyma transection-first” strategy is safe and feasible compared with traditional “tunnel-first strategy” in SPDP with Kimura’s procedure.

Bottom-up holistic carrier management strategy induced synergistically by multiple chemical bonds to minimize energy losses for efficient and stable perovskite solar cells

The defects from electron transport layer,perovskite layer and their interface would result in carrier nonradiative recombination losses.Poor buried interfacial contact is detrimental to charge extraction and device stability.Here,we report a bottom-up holistic carrier management strategy induced synergistically by multiple chemical bonds to minimize bulk and interfacial energy losses for high-performance perovskite photovoltaics.4-trifluoromethyl-benzamidine hydrochloride(TBHCl)containing–CF_(3),amidine cation and Cl^(-)is in advance incorporated into SnO_(2)colloid solution to realize bottom-up modification.The synergistic effect of multiple functional groups and multiple-bond-induced chemical interaction are revealed theoretically and experimentally.F and Cl^(-)can passivate oxygen vacancy and/or undercoordinated Sn^(4+)defects by coordinating with Sn^(4+).The F can suppress cation migration and modulate crystallization via hydrogen bond with FA^(+),and can passivate lead defects by coordinating with Pb^(2+).The–NH_(2)–C=NH^(+)_(2)and Cl^(-)can passivate cation and anion vacancy defects through ionic bonds with perovskites,respectively.Through TBHCl modification,the suppression of agglomeration of SnO_(2)nanoparticles,bulk and interfacial defect passivation,and release of tensile strains of perovskite films are demonstrated,which resulted in a PCE enhancement from 21.28%to 23.40%and improved stability.With post-treatment,the efficiency is further improved to 23.63%.

The Full Load Voltage Compensation Strategy in Capacity Configuration of UPQC Integrated PV-BESS

Unified power quality conditioner(UPQC)with energy storage is commonly based on conventional capacity configuration strategy with power angle control.It has problems such as phase jumping before and after compensation.DC-link cannot continuously emit active power externally.Therefore,this paper presents the compensation strategy of full load voltage magnitude and phase in capacity configuration of UPQC.The topology of UPQC is integrated a series active power filter(SAPF),a shunt active power filter(PAPF)and a photovoltaic-battery energy storage system(PV-BESS).The principle of full load voltage compensation is analyzed based on the PV-BESS-UPQC topology.Themagnitude constant of load voltage ismaintained by controlling the appropriate shunt compensation current.Then the UPQC capacity configuration is carried out using the full load voltage compensation strategy.The compensation capacity of UPQC series and shunt units are reduced.Finally,the simulation results show that the proposed compensation strategy reduces the capacity configuration by 5.11 kVA(36.4%)compared to the conventional compensation strategy.The proposed strategy can achieve full compensation of the load voltage,which can effectively reduce the capacity allocation and improve the economy of UPQC.It also has the PV-BESS units’ability of providing active power and can stabilize the DC-link voltage.

Pooled Sputum for Xpert MTB/RIF Testing: A Cost-Saving Strategy in Mwanza, Tanzania

Background: Tuberculosis (TB) diagnostics, such as Xpert MTB/RIF, is still limited by cost. Testing of pooled samples from presumptive TB patients has been thought as a cost-saving strategy to diagnose TB. We assessed the utility and cost-saving of pooled Xpert MTB/RIF testing strategy for the diagnosis of TB in Mwanza, Tanzania. Methods: Sputum samples from Presumptive TB patients were submitted to TB laboratory for routine diagnosis of TB using Xpert MTB/RIF. The TB results from the individual sputum samples were used as the reference standard and were concealed to the investigating laboratory technicians. The remainder of samples were collected serially and were pooled (5 samples per pool) for testing. The agreement of the results between individual sample testing against pooled sample testing and cost-savings was assessed. Results: A total of 250 sputum samples from presumptive TB patients were analyzed and 50 pools were made with each pool containing 5 samples. Of the 50 sputum pools made, Mycobacterium tuberculosis (MTB) was detected in 17 (34.0%) pools. Results from the individual sputum samples MTB/RIF testing were retrieved for all 250 samples and there were 28 (11.2%) samples in which MTB was detected whereas 222 (88.8%) samples had no MTB detected. Following re-analysis of positive pools, all 28 (100%) individual positive MTB samples were detected within the 17 positive pools, with 1 to 3 individual MTB positive samples per pool. The individual sputum samples were correctly identified by pooled sputum on Xpert MTB/RIF testing, with the sensitivity of 100% and specificity of 100%. Using pooling of sputum samples strategy, we saved 46.0% (115/250) of the cartridges. Conclusion: The pooled sputum testing strategy reduced cartridge costs by 46.0% and has the potential to increase the affordability of Xpert MTB/RIF testing in countries with limited resources, such as Tanzania.

The New “Waterways and Sea Canals” Strategy in the “Continent of Asia” and Its Implications on the Global Map

This paper reviews a strategic scientific proposal to dig and construct three navigable sea lanes linking isolated inland seas and blocked side bays and linking it with the open seas, to facilitate the movement of free trade and international navigation, and to break the captivity of geographically isolated environments, and to give a strategic advantage to some areas and sectors that are neglected politically, socially, economically and environmentally, and to adopt the strategy of establishing a marine channel between the “Caspian Sea” and the “Black Sea” through the “lands belonging to Russia”. On digging a navigational canal at the lowest cost in a plain area within the territory of Russia, with a length of approximately 600 kilometers (616 km), starting from the nearest bay in the Caspian Sea, passing near the city of “Pyatigorsk” to the city of “Sochi” on the Black Sea, while it comes: -The strategy of the waterway and the sea channel between the “Caspian Sea” and the “Arabian Gulf” through the “lands belonging to Iran” by digging and cutting a path in the rocks with a width of 100 meters and a length of about 700 kilometers, and at a time rate of less than 10 years, and this project will liberate all countries in the Caspian Sea, and the study concludes with the strategy of the navigational channel between the “Arabian Gulf” and the “Mediterranean Sea” through the two countries of “Iraq-Syria”, with a length of about 1350 km, and the world will benefit in the security, commercial and political fields.

The Institut Pasteur of Côte D’Ivoire (Ivory Coast) in the Emergency Management of Air Travellers during the COVID-19 Pandemic: A Unique Experience in Supporting the Response Strategy in Côte D’Ivoire from 2021 to 2022

Since its outbreak in December 2019 in Wuhan Province (China), the Coronavirus (COVID-19) disease quickly spread around the world in such a way that most response plans were outdated. There was an urgent need to change and adapt response strategies as the virus globally spread. Entire firms and economies were brought to a standstill in order to reduce the virus’ capacity to spread and to limit some of the short-term impacts in order to save time and find out solutions to come back to a more or less normal way of life. Thus, most of the countries that closed their air, sea and land borders had to reopen them progressively, with travel restrictions submitted to rigid controls. In Côte d’Ivoire, as in all other countries, air travellers leaving the territory were required to provide a certificate for a negative COVID-19 test, valid for 24 to 72 hours depending on the country of destination. However, the national system implemented could not provide a result before 48 hours. The objective of this work was to develop an alternative strategy to the system for air travellers who were in a hurry and those who had a computer bug in obtaining their result. A total of 38,444 air travellers benefited from this strategy implemented by the Institut Pasteur de Côte d’Ivoire during these two years.

Self-assembling peptide nanofibrous hydrogel as a promising strategy in nerve repair after traumatic injury in the nervous system

Following injury in central nervous system（CNS）,there are pathological changes in the injured region,which include neuronal death,axonal damage and demyelination,inflammatory response and activation of glial cells.The proliferation of a large number of astrocytes results in the formation of glial scar.

Dynamic capabilities-based strategy innovation： a theoretical framework and empirical studies in Chinese firms

Based on investigations of 112 Chinese firms and studies on foreign leading corporations, a theoretical framework of dynamic capabilities based strategy innovation (SI) is put forward. Several large firms in China winning through SI were studied empirically. This paper complements previous publications on the theories of innovation and strategy. This work's findings will be useful for managers interested in our approach, which highlights the importance of SI and focuses on and points out the major pitfalls in the innovation processes. Implementing the dynamic capabilities based strategy innovation can effectively cultivate and develop core competences of corporations. It is concluded that implementing SI is the only path for Chinese enterprise growth in the intensified competition in the knowledge economy.

Impact of Operational Process Factors on Strategy Implementation in Microfinance Organisations in a Developing Country

This paper sets to explore management perceptions regarding the impact of operational process factors on strategy implementation in microfinance organisations in Kenya.Small and medium enterprises(SMEs)play a critical role in developing countries as a source of employment creation and a basis for industrialization.However,the sector receives inadequate financial support from commercial banks as it is considered to bear high risks and operational costs associate with lending small loan amounts.Microfinance organisations(MFOs)that serve this sector will need to expand their operations to increase their outreach to SMEs.Formulation and implementation of competitive strategies will enable MFOs to achieve growth and sustainability.Content,context and operational process factors appear to have a significance positive relationship to the level of strategy implementation.This paper is focusing on operational process factors impacting on strategy implementation and is part of a full study on the topic of strategy implementation in MFOs.Comprehensive literature review provided the theoretical framework for the study.Primary data were collected by means of a survey obtaining 300 self-administered questionnaires from managers in 135 MFOs in Kenya.The study revealed that the level of strategy implementation in MFOs in Kenya is moderate to high.This study has revealed that the operational process category of factors is more significant to the level of strategy implementation than content and context factors.Five operational process factors critical to strategy implementation include:operational planning and monitoring,management control systems,people-strategy fit,teamwork,and effective communication.Further,the level of strategy implementation has significance positive influence to MFOs’financial sustainability and outreach.Practical guidelines are provided to assist MFOs in developing countries to improve the level of strategy implementation by focusing on operational process factors.

On the Application of Cognitive Strategy in College English Listening Comprehension——With International Talents Training as the Goal

This paper, with the training of the international talents possessing remarkable English listening and speaking ability,mainly discusses the specific application of the cognitive strategy in different stages of college English listening comprehension.It is expected that the paper can bring some useful enlightenments on the international talents training.

The Effects of Integrating Language Learning Strategy into EFL Instruction for Non-English Major Students in Vocational Technical Colleges

Language learning strategies play an important role in language learning. Students in vocational technical colleges have been regarded as low English proficiency learners due to their weak foundation in learning English. To explore the solution, the present study employed a specific survey of language learning strategy use and tried to conduct a one-semester language learning strategy training, aiming to investigate the effects of integrating language learning strategy into EFL instruction for non-English major students in vocational technical colleges. We found after the instruction, the difference in the frequency of overall strategy use between the experimental group and the control group was significant indicating that the students could be trained with language learning strategies to enhance the frequency of their strategy use. After language learning strategy instruction, the experimental group didn＇t perform significantly better than the control group in terms of their English language proficiency. However, the results of this present study still supported this viewpoint that the strategy instruction had positive impacts to some extent if properly conducted, for it had positive effects on enhancing students＇ language learning strategy use.

IMPLEMENTATION OF THE TRADE MARK STRATEGY IN FOREIGN TRADE AND ECONOMY

Trade marks are the marks of thecommodities and services. They arealso passes for the enterprises to enterthe market, and can reflect the economicbenefits and credit of the enterprises in acomprehensive manner. With thedevelopment of the market economy and theexpansion of foreign trade and business,trade marks are playing a more and moreimportant role in the economy. To establishits own famous brands as well as to protectthe trade marks more effectively, China willspeed up its steps to implement the

Language learning strategy in helping Chinese EFL university students with CET4 Written Test as a goal

This article discusses the application of theories in the field of learning strategies to ELT classroom in Chinese universities.By reviewing the literature of learning strategies,this article examines the possible connection between theories and the Chinese ELT classroom in specific,in which it focuses on the requirements of CET 4 examination.By doing so,this article tries to offer some suggestions that could be used in the classroom.

Research on Application of Metacognitive Strategy in English Listening in the Web-based Self-access Learning Environment

Metacognitive strategies are regarded as advanced strategies in all the learning strategies.This study focuses on the application of metacognitive strategies in English listening in the web-based self-access learning environment(WSLE) and tries to provide some references for those students and teachers in the vocational colleges.

Exploration on Learning Strategy in Second Language Acquisition

Learning strategies can be seen as particular techniques used by learners to have a good mastery of a second language.This articles aims to summarize the different opinions about learning strategies from different scholars in the hope of inspiring peo⁃ple to seek for more efficient strategies to be successful learners.