The rapid development of information technology provides a new opportunity and impetus for the reform of education and teaching.Deep integration of information technology and education and teaching is the only way to ...The rapid development of information technology provides a new opportunity and impetus for the reform of education and teaching.Deep integration of information technology and education and teaching is the only way to promote the modernization of education.Starting from the connotation of the deep integration of information technology and education and teaching,this paper analyzes the existing problems in the current integration process,and puts forward innovative strategies from the aspects of concept,resources,model,and evaluation.Through measures such as building a smart teaching environment,enriching high-quality teaching resources,innovating teaching organization models,and establishing multiple evaluation systems,we will realize the deep integration of information technology and teaching,promote the reform of teaching and learning methods,improve the quality of personnel training,and provide strong support for the modernization of education.展开更多
Through conducting a SWOT analysis of the Chengdu Sports Institute Museum,and utilizing the 4M management,5W display,and 4P marketing theoretical models,this study explores effective strategies suitable for Sichuan sp...Through conducting a SWOT analysis of the Chengdu Sports Institute Museum,and utilizing the 4M management,5W display,and 4P marketing theoretical models,this study explores effective strategies suitable for Sichuan sports museums in terms of functionality,display,and marketing.展开更多
The professional and moral education of high school mathematics teachers will make classroom management work better,but their work pressure will also lead to classroom management problems.To do a good job in high scho...The professional and moral education of high school mathematics teachers will make classroom management work better,but their work pressure will also lead to classroom management problems.To do a good job in high school class teacher management and organically integrate it with mathematics teaching,we need to start from two aspects:mathematics teaching class teachers and class teacher work teaching,and penetrate mathematical thinking into daily classroom management,moral education,and classroom culture construction.Based on the attributes of the subject,we guide high school students to reflect after class to stimulate their self-management initiative through the cultivation of qualified class representatives.In addition,it is necessary to skillfully resolve classroom generative problems,change the roles of teachers and students,and integrate classroom management with mathematics teaching.展开更多
The metropolitan area is one of the key focal points in the construction and development of China’s new urbanization.Urban integration is an emerging trend in metropolitan areas.This paper explores the traffic demand...The metropolitan area is one of the key focal points in the construction and development of China’s new urbanization.Urban integration is an emerging trend in metropolitan areas.This paper explores the traffic demand characteristics and economic aspects of rail transit within metropolitan regions and argues that the construction of an integrated urban rail transit network is an effective approach to support their development.Rail transit in metropolitan areas offers both technical and economic advantages,improving the efficiency of time and space resource utilization,fostering economic cooperation,and ultimately contributing to an integrated development model.However,the integration of rail transit networks faces several challenges,including road network planning,technical standards,and operational organization.Using the Wuhan metropolitan area as a case study,this paper analyzes the challenges of rail transit network integration and proposes strategic solutions for development.展开更多
To further enhance the effectiveness of talent cultivation for interior design in vocational colleges,it is necessary to vigorously promote the construction of an industry-education integration model.Through this mode...To further enhance the effectiveness of talent cultivation for interior design in vocational colleges,it is necessary to vigorously promote the construction of an industry-education integration model.Through this model,the roles of both enterprises and schools can be leveraged to jointly facilitate the continuous improvement of students’professional abilities and practical skills,providing a steady stream of high-quality talents for the development of the interior design field.Therefore,this paper analyzes the current issues in interior design talent cultivation in vocational colleges from the perspective of industry-education integration and proposes corresponding improvement measures.展开更多
Objective:We investigated the relation between man papillomavirus(HPV)integration status and the immediate risk of cervical intraepithelial neoplasia(CIN),as well as the triage strategy based on HPV integration test.M...Objective:We investigated the relation between man papillomavirus(HPV)integration status and the immediate risk of cervical intraepithelial neoplasia(CIN),as well as the triage strategy based on HPV integration test.Methods:4086 women aged 20 to 65 years in China were enrolled in 2015 for a prospective,population-based,clinical observational study to evaluate the triage performance of HPV integration.Cervical exfoliated cells were collected for HPV testing and cytologic test.If high-risk HPV was positive,HPV integration test was performed at baseline,2-year and 5-year follow-up.Results:At baseline,HPV integration was positively correlated with the severity of cervical pathology,ranging from 5.0%(15/301)in normal diagnosis,6.9%(4/58)in CIN1,31.0%(9/29)in CIN2,70%(14/20)in CIN3,and 100%(2/2)in cervical cancer(P<0.001).Compared with cytology,HPV integration exhibits comparable sensitivity and negative predictive value for the diagnosis of CIN3+,higher specificity(92.8%[90.2%-95.4%]vs.75.5%[71.2%-79.8%],P<0.001)and higher positive predictive value(36.4%[22.1%-50.6%]vs.15.2%[8.5%-21.8%],P<0.001).HPV integration testing strategy yielded a significantly lower colposcopy referral rate than cytology strategy(10.7%[44/410]vs.27.3%[112/410],P<0.001).The HPV integration-negative group exhibited the lowest immediate risk for CIN3+(1.6%)and accounted for the largest proportion of the total population(89.3%),when compared with the normal cytology group(risk,1.7%;proportion,72.7%).Conclusion:As a key molecular basis for the development of cervical cancer,HPV integration might be a promising triage strategy for HPV-positive patients.展开更多
Chongqing Z County E-sports Town was once included in the“first batch of sports and leisure characteristic town pilot project list”issued by the General Administration of Sports of China.After several years of devel...Chongqing Z County E-sports Town was once included in the“first batch of sports and leisure characteristic town pilot project list”issued by the General Administration of Sports of China.After several years of development,the e-sports industry in Z County e-sports town has struggled with issues such as a limited market,low popularity,poor business performance,and a lack of income generation capabilities.These challenges have severely hindered the town’s development,resulting in its exclusion from the recent“Chongqing characteristic town list.”Under the requirements of new policies,it can no longer promote itself,attract investment,or undertake project construction under the name of a“characteristic town”and must undergo redevelopment.This paper employs case analysis and comparative investigation methods to conduct an in-depth empirical study on the development of Z County E-sports Town.It is proposed that under the new policy environment,the town should foster the deep integration of its existing e-sports industry and culture with tourism and agriculture,transforming Z County E-sports Town into a new characteristic tourist destination.The findings of this paper offer a reference for the development of similar towns facing stagnation and provide case support for the construction of tourist destinations featuring e-sports.展开更多
In the perspective of natural geological climate and social economic situation of Chengdu City,the paper had analyzed the tendency of integration of urban-rural development in Chengdu,and proposed strategy to construc...In the perspective of natural geological climate and social economic situation of Chengdu City,the paper had analyzed the tendency of integration of urban-rural development in Chengdu,and proposed strategy to construct world modern garden city.It had illustrated basic conditions to construct world modern garden city in Chengdu at current period,and it was considered that good timing,geographical convenience and good human relations were involved in this strategy.In order to satisfy the six traits of word modern garden city,it had proposed short-term,mid-term and long-term targets;and focused on industrial development,enriching and benefiting the people,opening up to the outside world and institutional innovation.It also suggested weakening original economic geological pattern of Chengdu,so as to form complete urban system of sharing homogeneity of market construction,policy allocation,basic facilities,and social security system,seek for general welfare and diverse cooperation,and finally construct world modern garden city with good living environment,excellent investment environment,fine cultural atmosphere,high functional level,and strong comprehensive competitiveness.展开更多
El Niño-Southern Oscillation(ENSO)is the strongest interannual climate mode influencing the coupled ocean-atmosphere system in the tropical Pacific,and numerous dynamical and statistical models have been develope...El Niño-Southern Oscillation(ENSO)is the strongest interannual climate mode influencing the coupled ocean-atmosphere system in the tropical Pacific,and numerous dynamical and statistical models have been developed to simulate and predict it.In some simplified coupled ocean-atmosphere models,the relationship between sea surface temperature(SST)anomalies and wind stress(τ)anomalies can be constructed by statistical methods,such as singular value decomposition(SVD).In recent years,the applications of artificial intelligence(AI)to climate modeling have shown promising prospects,and the integrations of AI-based models with dynamical models are active areas of research.This study constructs U-Net models for representing the relationship between SSTAs andτanomalies in the tropical Pacific;the UNet-derivedτmodel,denoted asτUNet,is then used to replace the original SVD-basedτmodel of an intermediate coupled model(ICM),forming a newly AI-integrated ICM,referred to as ICM-UNet.The simulation results obtained from ICM-UNet demonstrate their ability to represent the spatiotemporal variability of oceanic and atmospheric anomaly fields in the equatorial Pacific.In the ocean-only case study,theτUNet-derived wind stress anomaly fields are used to force the ocean component of the ICM,the results of which also indicate reasonable simulations of typical ENSO events.These results demonstrate the feasibility of integrating an AI-derived model with a physics-based dynamical model for ENSO modeling studies.Furthermore,the successful integration of the dynamical ocean models with the AI-based atmospheric wind model provides a novel approach to ocean-atmosphere interaction modeling studies.展开更多
Prediction has become more and more difficult in mineral exploration, especially in the mature exploration environment such as Tongling copper district. For enhancing predictive discovery of hidden ore deposits in suc...Prediction has become more and more difficult in mineral exploration, especially in the mature exploration environment such as Tongling copper district. For enhancing predictive discovery of hidden ore deposits in such mature environment, the key strategies which should be adopted include the innovation of the exploration models, application of the advanced exploration techniques and integration of multiple sets of information. The innovation of the exploration models should incorporate the new metallogenic concepts that are based on the geodynamic anatomization. The advanced techniques applied in the mature exploration environment should aim at the speciality and complexity of the geological setting and working environments. The information synthesis is to integrate multiple sets of data for giving a more credible and visual prospectivity map by using the geographic imformation system(GIS) and several mathematical methods, such as weight of evidence and fuzzy logic, which can extract useful information from every set of data as much as possible. Guided by these strategies, a predictive exploration in Fenghuangshan ore field of Tongling copper district was implemented, and a hidden ore deposit was discovered.展开更多
In this study,we present a novel nodal integration-based particle finite element method(N-PFEM)designed for the dynamic analysis of saturated soils.Our approach incorporates the nodal integration technique into a gene...In this study,we present a novel nodal integration-based particle finite element method(N-PFEM)designed for the dynamic analysis of saturated soils.Our approach incorporates the nodal integration technique into a generalised Hellinger-Reissner(HR)variational principle,creating an implicit PFEM formulation.To mitigate the volumetric locking issue in low-order elements,we employ a node-based strain smoothing technique.By discretising field variables at the centre of smoothing cells,we achieve nodal integration over cells,eliminating the need for sophisticated mapping operations after re-meshing in the PFEM.We express the discretised governing equations as a min-max optimisation problem,which is further reformulated as a standard second-order cone programming(SOCP)problem.Stresses,pore water pressure,and displacements are simultaneously determined using the advanced primal-dual interior point method.Consequently,our numerical model offers improved accuracy for stresses and pore water pressure compared to the displacement-based PFEM formulation.Numerical experiments demonstrate that the N-PFEM efficiently captures both transient and long-term hydro-mechanical behaviour of saturated soils with high accuracy,obviating the need for stabilisation or regularisation techniques commonly employed in other nodal integration-based PFEM approaches.This work holds significant implications for the development of robust and accurate numerical tools for studying saturated soil dynamics.展开更多
Improving the reversibility of anionic redox and inhibiting irreversible oxygen evolution are the main challenges in the application of high reversible capacity Li-rich Mn-based cathode materials.A facile synchronous ...Improving the reversibility of anionic redox and inhibiting irreversible oxygen evolution are the main challenges in the application of high reversible capacity Li-rich Mn-based cathode materials.A facile synchronous lithiation strategy combining the advantages of yttrium doping and LiYO_(2) surface coating is proposed.Yttrium doping effectively suppresses the oxygen evolution during the delithiation process by increasing the energy barrier of oxygen evolution reaction through strong Y–O bond energy.LiYO_(2) nanocoating has the function of structural constraint and protection,that protecting the lattice oxygen exposed to the surface,thus avoiding irreversible oxidation.As an Li^(+) conductor,LiYO_(2) nano-coating can provide a fast Li^(+) transfer channel,which enables the sample to have excellent rate performance.The synergistic effect of Y doping and nano-LiYO_(2) coating integration suppresses the oxygen release from the surface,accelerates the diffusion of Li^(+)from electrolyte to electrode and decreases the interfacial side reactions,enabling the lithium ion batteries to obtain good electrochemical performance.The lithium-ion full cell employing the Y-1 sample(cathode)and commercial graphite(anode)exhibit an excellent specific energy density of 442.9 Wh kg^(-1) at a current density of 0.1C,with very stable safety performance,which can be used in a wide temperature range(60 to-15℃)stable operation.This result illustrates a new integration strategy for advanced cathode materials to achieve high specific energy density.展开更多
The rising frequency of extreme disaster events seriously threatens the safe and secure operation of the regional integrated electricity-natural gas system(RIENGS).With the growing level of coupling between electric a...The rising frequency of extreme disaster events seriously threatens the safe and secure operation of the regional integrated electricity-natural gas system(RIENGS).With the growing level of coupling between electric and natural gas systems,it is critical to enhance the load restoration capability of both systems.This paper proposes a coordinated optimization strategy for resilience-enhanced RIENGS load restoration and repair scheduling and transforms it into a mixed integer second-order cone programming(MISOCP)model.The proposed model considers the distribution network reconfiguration and the coordinated repair strategy between the two systems,minimizing the total system load loss cost and repair time.In addition,a bi-directional gas flow model is used to describe the natural gas system,which can provide the RIENGS with more flexibility for load restoration during natural gas system failure.Finally,the effectiveness of the proposed approach is verified by conducting case studies on the test systems RIENGS E13-G7 and RIENGS E123-G20.展开更多
Inferior crude oil and fuel oil upgrading lead to escalating increase of hydrogen consumption in refineries.It is imperative to reduce the hydrogen consumption for energy-saving operations of refineries.An integration...Inferior crude oil and fuel oil upgrading lead to escalating increase of hydrogen consumption in refineries.It is imperative to reduce the hydrogen consumption for energy-saving operations of refineries.An integration strategy of hydrogen network and an operational optimization model of hydrotreating(HDT)units are proposed based on the characteristics of reaction kinetics of HDT units.By solving the proposed model,the operating conditions of HDT units are optimized,and the parameters of hydrogen sinks are determined by coupling hydrodesulfurization(HDS),hydrodenitrification(HDN)and aromatic hydrogenation(HDA)kinetics.An example case of a refinery with annual processing capacity of eight million tons is adopted to demonstrate the feasibility of the proposed optimization strategies and the model.Results show that HDS,HDN and HDA reactions are the major source of hydrogen consumption in the refinery.The total hydrogen consumption can be reduced by 18.9%by applying conventional hydrogen network optimization model.When the hydrogen network is optimized after the operational optimization of HDT units is performed,the hydrogen consumption is reduced by28.2%.When the benefit of the fuel gas recovery is further considered,the total annual cost of hydrogen network can be reduced by 3.21×10~7CNY·a^(-1),decreased by 11.9%.Therefore,the operational optimization of the HDT units in refineries should be imposed to determine the parameters of hydrogen sinks base on the characteristics of reaction kinetics of the hydrogenation processes before the optimization of the hydrogen network is performed through the source-sink matching methods.展开更多
The performance of optical interconnection has improved dramatically in recent years.Silicon-based optoelectronic heterogeneous integration is the key enabler to achieve high performance optical interconnection,which ...The performance of optical interconnection has improved dramatically in recent years.Silicon-based optoelectronic heterogeneous integration is the key enabler to achieve high performance optical interconnection,which not only provides the optical gain which is absent from native Si substrates and enables complete photonic functionalities on chip,but also improves the system performance through advanced heterogeneous integrated packaging.This paper reviews recent progress of silicon-based optoelectronic heterogeneous integration in high performance optical interconnection.The research status,development trend and application of ultra-low loss optical waveguides,high-speed detectors,high-speed modulators,lasers and 2D,2.5D,3D and monolithic integration are focused on.展开更多
The development of a core collection could enhance the utilization of germplasm collections in crop improvement programs and simplify their management. Selection of an appropriate sampling strategy is an important pre...The development of a core collection could enhance the utilization of germplasm collections in crop improvement programs and simplify their management. Selection of an appropriate sampling strategy is an important prerequisite to construct a core collection with appropriate size in order to adequately represent the genetic spectrum and maximally capture the genetic diversity in available crop collections. The present study was initiated to construct nested core collections to determine the appropriate sample size to represent the genetic diversity of rice landrace collection based on 15 quantitative traits and 34 qualitative traits of 2 262 rice accessions. The results showed that 50-225 nested core collections, whose sampling rate was 2.2%-9.9%, were sufficient to maintain the maximum genetic diversity of the initial collections. Of these, 150 accessions (6.6%) could capture the maximal genetic diversity of the initial collection. Three data types, i.e. qualitative traits (QT1), quantitative traits (QT2) and integrated qualitative and quantitative traits (QTT), were compared for their efficiency in constructing core collections based on the weighted pair-group average method combined with stepwise clustering and preferred sampling on adjusted Euclidean distances. Every combining scheme constructed eight rice core collections (225, 200, 175, 150, 125, 100, 75 and 50). The results showed that the QTT data was the best in constructing a core collection as indicated by the genetic diversity of core collections. A core collection constructed only on the information of QT1 could not represent the initial collection effectively. QTT should be used together to construct a productive core collection.展开更多
Bloody Mahjong is a kind of mahjong.It is very popular in China in recent years.It not only has the characteristics of mahjong's conventional state space,huge hidden information,complicated rules,and large randomn...Bloody Mahjong is a kind of mahjong.It is very popular in China in recent years.It not only has the characteristics of mahjong's conventional state space,huge hidden information,complicated rules,and large randomness of hand cards but also has special rules such as Change three,Hu must lack at least one suit,and Continue playing after Hu.These rules increase the difficulty of research.These special rules are used as the input of the deep learning DenseNet model.DenseNet is used to extract the Mahjong situation features.The learned features are used as the input of the classification algorithm XGBoost,and then the XGBoost algorithm is used to derive the card strategy.Experiments show that the fusion model of deep learning and XGBoost proposed in this paper has higher accuracy than the single model using only one of them in the case of highdimensional sparse features.In the case of fewer training rounds,accuracy of the model can still reach 83%.In the games against real people,it plays like human.展开更多
We propose the OrientI approach for effectively building flexible applications on information integration. The system presents a fully visual development environment to build applications. With OrientI system, a user ...We propose the OrientI approach for effectively building flexible applications on information integration. The system presents a fully visual development environment to build applications. With OrientI system, a user only needs to concentrate on the composition of components for building the InterPlan, and the detailed underlying operations and data streams are invisible to the user. A prototype system has been implemented and has partially proved the convenience brought by the OrientI approach. Key words Web - information integration - wrapper - XML - service CLC number TP 311.13 Foundation item: Supported by the 863 High Technology Foundation of China (2002AA116030), the Natural Science Foundation of China (60073014, 60273018), the Key Project of Chinese Ministry of Education (03044) and the Excellent Young Teachers Program of MOE, P.R.C. (EYTP)Biography: YI Lei(1980-), female, Master candidatc, research direction: Web information integration.展开更多
Aiming at solving the problems of response lag and lack of precision and stability in constant grinding force control of industrial robot belts,a constant force control strategy combining fuzzy control and proportion ...Aiming at solving the problems of response lag and lack of precision and stability in constant grinding force control of industrial robot belts,a constant force control strategy combining fuzzy control and proportion integration differentiation(PID)was proposed by analyzing the signal transmission process and the dynamic characteristics of the grinding mechanism.The simulation results showed that compared with the classical PID control strategy,the system adjustment time was shortened by 98.7%,the overshoot was reduced by 5.1%,and the control error was 0.2%-0.5%when the system was stabilized.The optimized fuzzy control system had fast adjustment speeds,precise force control and stability.The experimental analysis of the surface morphology of the machined blade was carried out by the industrial robot abrasive grinding mechanism,and the correctness of the theoretical analysis and the effectiveness of the control strategy were verified.展开更多
As the manufacturing process of silicon-based integrated circuits(ICs)approaches its physical limit,the quantum effect of silicon-based field-effect transistors(FETs)has become increasingly evident.And the burgeoning ...As the manufacturing process of silicon-based integrated circuits(ICs)approaches its physical limit,the quantum effect of silicon-based field-effect transistors(FETs)has become increasingly evident.And the burgeoning carbon-based semiconductor technology has become one of the most disruptive technologies in the post-Moore era.As one-dimensional nanomaterials,carbon nanotubes(CNTs)are far superior to silicon at the same technology nodes of FETs because of their excellent electrical transport and scaling properties,rendering them the most competitive material in the next-generation ICs technology.However,certain challenges impede the industrialization of CNTs,particularly in terms of material preparation,which significantly hinders the development of CNT-based ICs.Focusing on CNT-based ICs technology,this review summarizes its main technical status,development trends,existing challenges,and future development directions.展开更多
文摘The rapid development of information technology provides a new opportunity and impetus for the reform of education and teaching.Deep integration of information technology and education and teaching is the only way to promote the modernization of education.Starting from the connotation of the deep integration of information technology and education and teaching,this paper analyzes the existing problems in the current integration process,and puts forward innovative strategies from the aspects of concept,resources,model,and evaluation.Through measures such as building a smart teaching environment,enriching high-quality teaching resources,innovating teaching organization models,and establishing multiple evaluation systems,we will realize the deep integration of information technology and teaching,promote the reform of teaching and learning methods,improve the quality of personnel training,and provide strong support for the modernization of education.
基金Key Research Base for Humanities and Social Sciences(Sports and Social Sciences)of the Education Department of the Sichuan Federation of Social Sciences Project:“Research on Development Strategies of Sichuan Local Sports Museums under the Background of Cultural and Tourism Integration”(Project No.TY2023210)。
文摘Through conducting a SWOT analysis of the Chengdu Sports Institute Museum,and utilizing the 4M management,5W display,and 4P marketing theoretical models,this study explores effective strategies suitable for Sichuan sports museums in terms of functionality,display,and marketing.
文摘The professional and moral education of high school mathematics teachers will make classroom management work better,but their work pressure will also lead to classroom management problems.To do a good job in high school class teacher management and organically integrate it with mathematics teaching,we need to start from two aspects:mathematics teaching class teachers and class teacher work teaching,and penetrate mathematical thinking into daily classroom management,moral education,and classroom culture construction.Based on the attributes of the subject,we guide high school students to reflect after class to stimulate their self-management initiative through the cultivation of qualified class representatives.In addition,it is necessary to skillfully resolve classroom generative problems,change the roles of teachers and students,and integrate classroom management with mathematics teaching.
基金The Research Fund of Jianghan University(Project No.2021yb096)Hubei Social Science Foundation Project“Research on the Relationship between Rail Transit and Intensive and Sustainable Development of Large Cities”(Project No.2020052)。
文摘The metropolitan area is one of the key focal points in the construction and development of China’s new urbanization.Urban integration is an emerging trend in metropolitan areas.This paper explores the traffic demand characteristics and economic aspects of rail transit within metropolitan regions and argues that the construction of an integrated urban rail transit network is an effective approach to support their development.Rail transit in metropolitan areas offers both technical and economic advantages,improving the efficiency of time and space resource utilization,fostering economic cooperation,and ultimately contributing to an integrated development model.However,the integration of rail transit networks faces several challenges,including road network planning,technical standards,and operational organization.Using the Wuhan metropolitan area as a case study,this paper analyzes the challenges of rail transit network integration and proposes strategic solutions for development.
基金University-Level Teaching Reform Project“Research on Effective Models and Pathways for University-Enterprise Co-Construction of an Industry College Based on the School of Architecture and Urban Industry”(Q2310003)。
文摘To further enhance the effectiveness of talent cultivation for interior design in vocational colleges,it is necessary to vigorously promote the construction of an industry-education integration model.Through this model,the roles of both enterprises and schools can be leveraged to jointly facilitate the continuous improvement of students’professional abilities and practical skills,providing a steady stream of high-quality talents for the development of the interior design field.Therefore,this paper analyzes the current issues in interior design talent cultivation in vocational colleges from the perspective of industry-education integration and proposes corresponding improvement measures.
基金supported by the National Nature Science Foun-dation of China(grant numbers:82141106,81630060)the National Key Research and Development Program of China(grant number:2021YFC2701204)+2 种基金Key Technology R&D Program of Hubei(grant num-ber:2024BCB057)Panyu District Science and Technology Plan Project(grant number:2020-Z04-014)Guangzhou Health Science and Tech-nology Project(grant number:20221A011118).
文摘Objective:We investigated the relation between man papillomavirus(HPV)integration status and the immediate risk of cervical intraepithelial neoplasia(CIN),as well as the triage strategy based on HPV integration test.Methods:4086 women aged 20 to 65 years in China were enrolled in 2015 for a prospective,population-based,clinical observational study to evaluate the triage performance of HPV integration.Cervical exfoliated cells were collected for HPV testing and cytologic test.If high-risk HPV was positive,HPV integration test was performed at baseline,2-year and 5-year follow-up.Results:At baseline,HPV integration was positively correlated with the severity of cervical pathology,ranging from 5.0%(15/301)in normal diagnosis,6.9%(4/58)in CIN1,31.0%(9/29)in CIN2,70%(14/20)in CIN3,and 100%(2/2)in cervical cancer(P<0.001).Compared with cytology,HPV integration exhibits comparable sensitivity and negative predictive value for the diagnosis of CIN3+,higher specificity(92.8%[90.2%-95.4%]vs.75.5%[71.2%-79.8%],P<0.001)and higher positive predictive value(36.4%[22.1%-50.6%]vs.15.2%[8.5%-21.8%],P<0.001).HPV integration testing strategy yielded a significantly lower colposcopy referral rate than cytology strategy(10.7%[44/410]vs.27.3%[112/410],P<0.001).The HPV integration-negative group exhibited the lowest immediate risk for CIN3+(1.6%)and accounted for the largest proportion of the total population(89.3%),when compared with the normal cytology group(risk,1.7%;proportion,72.7%).Conclusion:As a key molecular basis for the development of cervical cancer,HPV integration might be a promising triage strategy for HPV-positive patients.
基金Humanities and Social Sciences Research Planning Fund of the Ministry of Education of the People’s Republic of China“Research on the Application and Improvement of the PPP Model for the Construction of Sports and Leisure Characteristic Towns Based on Value Chain Theory”(Project No.18XJA890002)。
文摘Chongqing Z County E-sports Town was once included in the“first batch of sports and leisure characteristic town pilot project list”issued by the General Administration of Sports of China.After several years of development,the e-sports industry in Z County e-sports town has struggled with issues such as a limited market,low popularity,poor business performance,and a lack of income generation capabilities.These challenges have severely hindered the town’s development,resulting in its exclusion from the recent“Chongqing characteristic town list.”Under the requirements of new policies,it can no longer promote itself,attract investment,or undertake project construction under the name of a“characteristic town”and must undergo redevelopment.This paper employs case analysis and comparative investigation methods to conduct an in-depth empirical study on the development of Z County E-sports Town.It is proposed that under the new policy environment,the town should foster the deep integration of its existing e-sports industry and culture with tourism and agriculture,transforming Z County E-sports Town into a new characteristic tourist destination.The findings of this paper offer a reference for the development of similar towns facing stagnation and provide case support for the construction of tourist destinations featuring e-sports.
文摘In the perspective of natural geological climate and social economic situation of Chengdu City,the paper had analyzed the tendency of integration of urban-rural development in Chengdu,and proposed strategy to construct world modern garden city.It had illustrated basic conditions to construct world modern garden city in Chengdu at current period,and it was considered that good timing,geographical convenience and good human relations were involved in this strategy.In order to satisfy the six traits of word modern garden city,it had proposed short-term,mid-term and long-term targets;and focused on industrial development,enriching and benefiting the people,opening up to the outside world and institutional innovation.It also suggested weakening original economic geological pattern of Chengdu,so as to form complete urban system of sharing homogeneity of market construction,policy allocation,basic facilities,and social security system,seek for general welfare and diverse cooperation,and finally construct world modern garden city with good living environment,excellent investment environment,fine cultural atmosphere,high functional level,and strong comprehensive competitiveness.
基金supported by the National Natural Science Foundation of China(NFSCGrant No.42030410)+2 种基金Laoshan Laboratory(No.LSKJ202202402)the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB40000000)the Startup Foundation for Introducing Talent of NUIST.
文摘El Niño-Southern Oscillation(ENSO)is the strongest interannual climate mode influencing the coupled ocean-atmosphere system in the tropical Pacific,and numerous dynamical and statistical models have been developed to simulate and predict it.In some simplified coupled ocean-atmosphere models,the relationship between sea surface temperature(SST)anomalies and wind stress(τ)anomalies can be constructed by statistical methods,such as singular value decomposition(SVD).In recent years,the applications of artificial intelligence(AI)to climate modeling have shown promising prospects,and the integrations of AI-based models with dynamical models are active areas of research.This study constructs U-Net models for representing the relationship between SSTAs andτanomalies in the tropical Pacific;the UNet-derivedτmodel,denoted asτUNet,is then used to replace the original SVD-basedτmodel of an intermediate coupled model(ICM),forming a newly AI-integrated ICM,referred to as ICM-UNet.The simulation results obtained from ICM-UNet demonstrate their ability to represent the spatiotemporal variability of oceanic and atmospheric anomaly fields in the equatorial Pacific.In the ocean-only case study,theτUNet-derived wind stress anomaly fields are used to force the ocean component of the ICM,the results of which also indicate reasonable simulations of typical ENSO events.These results demonstrate the feasibility of integrating an AI-derived model with a physics-based dynamical model for ENSO modeling studies.Furthermore,the successful integration of the dynamical ocean models with the AI-based atmospheric wind model provides a novel approach to ocean-atmosphere interaction modeling studies.
基金Project(2001CB409809) supported by the National Key Foundmental Research and Development Program of Chinaproject(1042610) supported by the Key Program of the Education Ministry of China
文摘Prediction has become more and more difficult in mineral exploration, especially in the mature exploration environment such as Tongling copper district. For enhancing predictive discovery of hidden ore deposits in such mature environment, the key strategies which should be adopted include the innovation of the exploration models, application of the advanced exploration techniques and integration of multiple sets of information. The innovation of the exploration models should incorporate the new metallogenic concepts that are based on the geodynamic anatomization. The advanced techniques applied in the mature exploration environment should aim at the speciality and complexity of the geological setting and working environments. The information synthesis is to integrate multiple sets of data for giving a more credible and visual prospectivity map by using the geographic imformation system(GIS) and several mathematical methods, such as weight of evidence and fuzzy logic, which can extract useful information from every set of data as much as possible. Guided by these strategies, a predictive exploration in Fenghuangshan ore field of Tongling copper district was implemented, and a hidden ore deposit was discovered.
基金supported by the Swiss National Science Foundation(Grant No.189882)the National Natural Science Foundation of China(Grant No.41961134032)support provided by the New Investigator Award grant from the UK Engineering and Physical Sciences Research Council(Grant No.EP/V012169/1).
文摘In this study,we present a novel nodal integration-based particle finite element method(N-PFEM)designed for the dynamic analysis of saturated soils.Our approach incorporates the nodal integration technique into a generalised Hellinger-Reissner(HR)variational principle,creating an implicit PFEM formulation.To mitigate the volumetric locking issue in low-order elements,we employ a node-based strain smoothing technique.By discretising field variables at the centre of smoothing cells,we achieve nodal integration over cells,eliminating the need for sophisticated mapping operations after re-meshing in the PFEM.We express the discretised governing equations as a min-max optimisation problem,which is further reformulated as a standard second-order cone programming(SOCP)problem.Stresses,pore water pressure,and displacements are simultaneously determined using the advanced primal-dual interior point method.Consequently,our numerical model offers improved accuracy for stresses and pore water pressure compared to the displacement-based PFEM formulation.Numerical experiments demonstrate that the N-PFEM efficiently captures both transient and long-term hydro-mechanical behaviour of saturated soils with high accuracy,obviating the need for stabilisation or regularisation techniques commonly employed in other nodal integration-based PFEM approaches.This work holds significant implications for the development of robust and accurate numerical tools for studying saturated soil dynamics.
基金This work was supported by the Fundamental Research Funds for the Central Universities(DUT20LAB123 and DUT20LAB307)the Natural Science Foundation of Jiangsu Province(BK20191167).
文摘Improving the reversibility of anionic redox and inhibiting irreversible oxygen evolution are the main challenges in the application of high reversible capacity Li-rich Mn-based cathode materials.A facile synchronous lithiation strategy combining the advantages of yttrium doping and LiYO_(2) surface coating is proposed.Yttrium doping effectively suppresses the oxygen evolution during the delithiation process by increasing the energy barrier of oxygen evolution reaction through strong Y–O bond energy.LiYO_(2) nanocoating has the function of structural constraint and protection,that protecting the lattice oxygen exposed to the surface,thus avoiding irreversible oxidation.As an Li^(+) conductor,LiYO_(2) nano-coating can provide a fast Li^(+) transfer channel,which enables the sample to have excellent rate performance.The synergistic effect of Y doping and nano-LiYO_(2) coating integration suppresses the oxygen release from the surface,accelerates the diffusion of Li^(+)from electrolyte to electrode and decreases the interfacial side reactions,enabling the lithium ion batteries to obtain good electrochemical performance.The lithium-ion full cell employing the Y-1 sample(cathode)and commercial graphite(anode)exhibit an excellent specific energy density of 442.9 Wh kg^(-1) at a current density of 0.1C,with very stable safety performance,which can be used in a wide temperature range(60 to-15℃)stable operation.This result illustrates a new integration strategy for advanced cathode materials to achieve high specific energy density.
基金funded by the Science and Technology Project of State Grid Jilin Electric Power Co.,Ltd.(Project Name:Research onDistributionNetworkResilience Assessment and Improvement Technology for Natural Disaster Areas).
文摘The rising frequency of extreme disaster events seriously threatens the safe and secure operation of the regional integrated electricity-natural gas system(RIENGS).With the growing level of coupling between electric and natural gas systems,it is critical to enhance the load restoration capability of both systems.This paper proposes a coordinated optimization strategy for resilience-enhanced RIENGS load restoration and repair scheduling and transforms it into a mixed integer second-order cone programming(MISOCP)model.The proposed model considers the distribution network reconfiguration and the coordinated repair strategy between the two systems,minimizing the total system load loss cost and repair time.In addition,a bi-directional gas flow model is used to describe the natural gas system,which can provide the RIENGS with more flexibility for load restoration during natural gas system failure.Finally,the effectiveness of the proposed approach is verified by conducting case studies on the test systems RIENGS E13-G7 and RIENGS E123-G20.
基金Supported by the National Natural Science Foundation of China(21376188,21676211)the Key Project of Industrial Science and Technology of Shaanxi Province(2015GY095)
文摘Inferior crude oil and fuel oil upgrading lead to escalating increase of hydrogen consumption in refineries.It is imperative to reduce the hydrogen consumption for energy-saving operations of refineries.An integration strategy of hydrogen network and an operational optimization model of hydrotreating(HDT)units are proposed based on the characteristics of reaction kinetics of HDT units.By solving the proposed model,the operating conditions of HDT units are optimized,and the parameters of hydrogen sinks are determined by coupling hydrodesulfurization(HDS),hydrodenitrification(HDN)and aromatic hydrogenation(HDA)kinetics.An example case of a refinery with annual processing capacity of eight million tons is adopted to demonstrate the feasibility of the proposed optimization strategies and the model.Results show that HDS,HDN and HDA reactions are the major source of hydrogen consumption in the refinery.The total hydrogen consumption can be reduced by 18.9%by applying conventional hydrogen network optimization model.When the hydrogen network is optimized after the operational optimization of HDT units is performed,the hydrogen consumption is reduced by28.2%.When the benefit of the fuel gas recovery is further considered,the total annual cost of hydrogen network can be reduced by 3.21×10~7CNY·a^(-1),decreased by 11.9%.Therefore,the operational optimization of the HDT units in refineries should be imposed to determine the parameters of hydrogen sinks base on the characteristics of reaction kinetics of the hydrogenation processes before the optimization of the hydrogen network is performed through the source-sink matching methods.
基金Project supported in part by the National Key Research and Development Program of China(Grant No.2021YFB2206504)the National Natural Science Foundation of China(Grant No.62235017)the China Postdoctoral Science Foundation(Grant No.2021M703125).
文摘The performance of optical interconnection has improved dramatically in recent years.Silicon-based optoelectronic heterogeneous integration is the key enabler to achieve high performance optical interconnection,which not only provides the optical gain which is absent from native Si substrates and enables complete photonic functionalities on chip,but also improves the system performance through advanced heterogeneous integrated packaging.This paper reviews recent progress of silicon-based optoelectronic heterogeneous integration in high performance optical interconnection.The research status,development trend and application of ultra-low loss optical waveguides,high-speed detectors,high-speed modulators,lasers and 2D,2.5D,3D and monolithic integration are focused on.
基金supported by the National Natural Science Foundation of China (Grant No. 30700494)the Principal Fund of South China Agricultural University, China (Grant No. 2003K053)
文摘The development of a core collection could enhance the utilization of germplasm collections in crop improvement programs and simplify their management. Selection of an appropriate sampling strategy is an important prerequisite to construct a core collection with appropriate size in order to adequately represent the genetic spectrum and maximally capture the genetic diversity in available crop collections. The present study was initiated to construct nested core collections to determine the appropriate sample size to represent the genetic diversity of rice landrace collection based on 15 quantitative traits and 34 qualitative traits of 2 262 rice accessions. The results showed that 50-225 nested core collections, whose sampling rate was 2.2%-9.9%, were sufficient to maintain the maximum genetic diversity of the initial collections. Of these, 150 accessions (6.6%) could capture the maximal genetic diversity of the initial collection. Three data types, i.e. qualitative traits (QT1), quantitative traits (QT2) and integrated qualitative and quantitative traits (QTT), were compared for their efficiency in constructing core collections based on the weighted pair-group average method combined with stepwise clustering and preferred sampling on adjusted Euclidean distances. Every combining scheme constructed eight rice core collections (225, 200, 175, 150, 125, 100, 75 and 50). The results showed that the QTT data was the best in constructing a core collection as indicated by the genetic diversity of core collections. A core collection constructed only on the information of QT1 could not represent the initial collection effectively. QTT should be used together to construct a productive core collection.
基金Promoting Research Level Program,Beijing Information Science and Technology University,Grant/Award Number:5211910927General Science and Technology Research program,Grant/Award Number:KM201911232002Graduated Education Program at Beijing Information Science and Technology University。
文摘Bloody Mahjong is a kind of mahjong.It is very popular in China in recent years.It not only has the characteristics of mahjong's conventional state space,huge hidden information,complicated rules,and large randomness of hand cards but also has special rules such as Change three,Hu must lack at least one suit,and Continue playing after Hu.These rules increase the difficulty of research.These special rules are used as the input of the deep learning DenseNet model.DenseNet is used to extract the Mahjong situation features.The learned features are used as the input of the classification algorithm XGBoost,and then the XGBoost algorithm is used to derive the card strategy.Experiments show that the fusion model of deep learning and XGBoost proposed in this paper has higher accuracy than the single model using only one of them in the case of highdimensional sparse features.In the case of fewer training rounds,accuracy of the model can still reach 83%.In the games against real people,it plays like human.
文摘We propose the OrientI approach for effectively building flexible applications on information integration. The system presents a fully visual development environment to build applications. With OrientI system, a user only needs to concentrate on the composition of components for building the InterPlan, and the detailed underlying operations and data streams are invisible to the user. A prototype system has been implemented and has partially proved the convenience brought by the OrientI approach. Key words Web - information integration - wrapper - XML - service CLC number TP 311.13 Foundation item: Supported by the 863 High Technology Foundation of China (2002AA116030), the Natural Science Foundation of China (60073014, 60273018), the Key Project of Chinese Ministry of Education (03044) and the Excellent Young Teachers Program of MOE, P.R.C. (EYTP)Biography: YI Lei(1980-), female, Master candidatc, research direction: Web information integration.
基金Civil Project of China Aerospace Science and Technology CorporationUniversity-Industry Collaborative Education Program of Ministry of Education of China(No.220906517214433)。
文摘Aiming at solving the problems of response lag and lack of precision and stability in constant grinding force control of industrial robot belts,a constant force control strategy combining fuzzy control and proportion integration differentiation(PID)was proposed by analyzing the signal transmission process and the dynamic characteristics of the grinding mechanism.The simulation results showed that compared with the classical PID control strategy,the system adjustment time was shortened by 98.7%,the overshoot was reduced by 5.1%,and the control error was 0.2%-0.5%when the system was stabilized.The optimized fuzzy control system had fast adjustment speeds,precise force control and stability.The experimental analysis of the surface morphology of the machined blade was carried out by the industrial robot abrasive grinding mechanism,and the correctness of the theoretical analysis and the effectiveness of the control strategy were verified.
基金supported by National Natural Science Foundation of China(Grant No.52022078)Shaanxi Provincial Key Research and Development Program(Grant No.2021ZDLGY10-02,2019ZDLGY01-09)。
文摘As the manufacturing process of silicon-based integrated circuits(ICs)approaches its physical limit,the quantum effect of silicon-based field-effect transistors(FETs)has become increasingly evident.And the burgeoning carbon-based semiconductor technology has become one of the most disruptive technologies in the post-Moore era.As one-dimensional nanomaterials,carbon nanotubes(CNTs)are far superior to silicon at the same technology nodes of FETs because of their excellent electrical transport and scaling properties,rendering them the most competitive material in the next-generation ICs technology.However,certain challenges impede the industrialization of CNTs,particularly in terms of material preparation,which significantly hinders the development of CNT-based ICs.Focusing on CNT-based ICs technology,this review summarizes its main technical status,development trends,existing challenges,and future development directions.