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On Plane Stress State and Stress Free Deformation of Thick Plate with FGM Interface under Thermal Loading
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作者 Damian Szubartowski Artur Ganczarski 《Journal of Thermal Science》 SCIE EI CAS CSCD 2016年第5期440-448,共9页
This paper demonstrates the plane stress state and the stress free thermo-elastic deformation of FGM thick plate under thermal loading.First,the Sneddon-Lockett theorem on the plane stress state in an isotropic infini... This paper demonstrates the plane stress state and the stress free thermo-elastic deformation of FGM thick plate under thermal loading.First,the Sneddon-Lockett theorem on the plane stress state in an isotropic infinite thick plate is generalized for a case of FGM problem in which all thermo-mechanical properties are optional functions of depth co-ordinate.The proof is based on application of the Iljushin thermo-elastic potential to displacement type system of equations that reduces it to the plane stress state problem.Then an existence of the purely thermal deformation is proved in two ways:first,it is shown that the unique solution fulfils conditions of simultaneous constant temperature and linear gradation of thermal expansion coefficient,second,proof is based directly on stress type system of equations which straightforwardly reduces to compatibility equations for purely thermal deformation if only stress field is homogeneous in domain and at boundary.Finally,couple examples of application to an engineering problem are presented. 展开更多
关键词 thick plate with FGM interface plane stress state stress free deformation
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Oxidative Stress and Free Radical Damage in Patients With Acute Dipterex Poisoning 被引量:15
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作者 JUN-FuZHOU WENZHOU +2 位作者 SHU-MEIZHANG YAN-ERLUO HUAI-HONGCHEN 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2004年第2期223-233,共11页
Objective To investigate whether acute dipterex poisoning (ADP) may cause oxidative stress and free radical damage in the bodies of acute dipterex poisoning patients (ADPPs), and to explore the mechanisms by which ADP... Objective To investigate whether acute dipterex poisoning (ADP) may cause oxidative stress and free radical damage in the bodies of acute dipterex poisoning patients (ADPPs), and to explore the mechanisms by which ADP may cause oxidative stress and free radical damage. Methods Fifty ADPPs and fifty healthy adult volunteers (HAVs) whose ages, gender and others were matched with the ADPPs were enrolled in a randomized controlled study, in which concentrations of nitric oxide (NO), vitamin C (VC), vitamin E (VE) and P-carotene (P-CAR) in plasma as well as concentration of lipoperoxide (LPO), and activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and acetylcholinesterase (AChE) in erythrocytes were determined by spectrophotometric analytical methods. Results Compared with the average values of experimental parameters in the HAVs group, the average values of plasma NO and erythrocyte LPO in the ADPPs group were significantly increased (P<0.0001), while those of plasma VC, VE and P-CAR as well as erythrocyte SOD, CAT, GPX and AChE in the ADPPs group were significantly decreased (P<0.0001). Bivariate correlation analysis and partial correlation analysis suggested that when NO and LPO values were increased, and VC, VE, β-CAR, SOD, CAT and GPX values were decreased in the ADPPs, AChE value was decreased gradually in the ADPPs (P<0.001-0.0001). Reliability analysis of experimental parameters reflecting oxidative stress and free radical damage in the ADPPs showed that the reliability coefficient (8 items) alpha=0.6909, and the standardized item alpha=0.8574. Conclusion The findings in the present study suggest that ADP can cause oxidative stress and free radical damage, and inhibit markedly erythrocyte acetylcholinesterase activity in ADPPs. 展开更多
关键词 Dipterex Dipterex poisoning Oxidative stress free radical damage free radicals Oxidation LIPOPEROXIDATION ACETYLCHOLINESTERASE
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May Chronic Childhood Constipation Cause Oxidative Stress and Potential Free Radical Damage to Children? 被引量:4
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作者 JI-YUEWANG YE-LINGWANG +1 位作者 SHENG-LIZHOU JUN-FUZHOU 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2004年第3期266-272,共7页
Objective To investigate whether chronic childhood constipation (CCC) may cause oxidative stress and potential free radical damage to children, and to explore the mechanisms by which CCC may cause oxidative stress an... Objective To investigate whether chronic childhood constipation (CCC) may cause oxidative stress and potential free radical damage to children, and to explore the mechanisms by which CCC may cause oxidative stress and potential free radical damage to chronic constipation patients (CCPs). Methods Sixty CCPs and sixty healthy child volunteers (HCVs) whose ages, gender and others were matched for the CCPs were enrolled in a randomized controlled study, in which levels of vitamin C (VC) and vitamin E (VE) in plasma as well as activities of superoxide dismutase (SOD) and catalase (CAT) in erythrocytes were determined by spectrophotometric analytical methods. Results Compared with average values of the above biochemical parameters in the HCVs group, the average values of VC and VE in plasma as well as those of SOD and CAT in erythrocytes in the CCPs group were significantly decreased (P<0.0001). Linear regression and bivariate correlation analysis showed that with prolonged course of the CCPs, the levels of VC and VE in plasma as well as the activities of SOD and CAT in erythrocytes in the CCPs were decreased gradually (P<0.0001). Conclusion The findings in the present study suggest that chronic childhood constipation causes oxidative stress and potential free radical damage to children with chronic constipation. 展开更多
关键词 Chronic childhood constipation Oxidative stress free radicals free radical damage Antioxidant Antioxidase
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A quadrilateral membrane hybrid stress element with drilling degrees of freedom 被引量:1
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作者 An-Ping Wang 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2012年第5期1367-1373,共7页
A new kind of quadrilateral assumed stress hy- brid membrane element with drilling degrees of freedom and a traction-free inclined side has been developed based on an extended Hellinger-Reissner principle which is est... A new kind of quadrilateral assumed stress hy- brid membrane element with drilling degrees of freedom and a traction-free inclined side has been developed based on an extended Hellinger-Reissner principle which is established by expanding the essential terms of the assumed stress field as polynomials in the natural coordinates of the element. The homogeneous equilibrium equations are imposed in a variational sense through the internal displacements which are also expanded in the natural coordinates, while the tractionfree conditions along the inclined side are satisfied exactly. The use of such special element in the finite element solution is shown to be highly accurate when only a very coarse element mesh is used for plates with V-shaped rounded notches or inclined sides. 展开更多
关键词 Hybrid stress element Drilling degrees of free-dom stress concentration Traction-free inclined side
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Influence of chemical reaction on heat and mass transfer of non-Newtonian fluid with yield stress by free convection from vertical surface in porous medium considering Soret effect 被引量:2
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作者 F. S. IBRAHIM F. M. HADY +1 位作者 S. M. ABDEL-GAIED M. R. EID 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2010年第6期675-684,共10页
The effect of chemical reaction on free convection heat and mass transfer for a non-Newtonian power law fluid over a vertical flat plate embedded in a fluid-saturated porous medium has been studied in the presence of ... The effect of chemical reaction on free convection heat and mass transfer for a non-Newtonian power law fluid over a vertical flat plate embedded in a fluid-saturated porous medium has been studied in the presence of the yield stress and the Soret effect. The governing boundary layer equations and boundary conditions are cast into a dimen- sionless form by similarity transformations, and the resulting system of equations is solved by a finite difference method. The results are preSented and discussed for concentration profiles, as well as the Nusselt number and the Sherwood number for various values of the parameters, which govern the problem. The results obtained show that the flow field is influenced appreciably by the presence of the chemical reaction parameter γ the order of.the chemical reaction parameter m, the Soret number St, the buoyancy ratio N, the Lewis number Le, and the dimensionless rheological parameter Ω. 展开更多
关键词 non-Newtonian fluid free convection chemical reaction yield stress Soret effect
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Effect of sodium salicylate on oxidative stress and insulin resistance induced by free fatty acids 被引量:10
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作者 He, Bing Zhao, Sheng +2 位作者 Zhang, Wei Li, Yan Han, Ping 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS 2010年第1期49-53,共5页
BACKGROUND: It has been reported that high-dose salicylates improve free fatty acids (FFAs)-induced insulin resistance and beta-cell dysfunction in vitro, but the mechanism remains uncertain. In insulin-resistant rats... BACKGROUND: It has been reported that high-dose salicylates improve free fatty acids (FFAs)-induced insulin resistance and beta-cell dysfunction in vitro, but the mechanism remains uncertain. In insulin-resistant rats, we found that the supplementation of sodium salicylate is associated with a reduction of plasma malondialdehyde (MDA), a marker of oxidative stress. Few studies have investigated the effects of salicylates on oxidative stress levels in insulin-resistant animal models. This study aimed to assess the effect of sodium salicylate on insulin sensitivity and to explore the potential mechanism by which it improves hepatic and peripheral insulin resistance. METHODS: Intralipid+heparin (IH), saline (SAL), or intralipid+heparin+sodium salicylate (IHS) were separately infused for 7 hours in normal Wistar rats. During the last 2 hours of the infusion, hyperinsulinemic-euglycemic clamping was 3 performed with [6-(3)H] glucose tracer. Plasma glucose was measured using the glucose oxygenase method. Plasma insulin and C-peptide were determined by radioimmunoassay. MDA levels and glutathione peroxidase (GSH-PX) activity in the liver and skeletal muscle were measured with colorimetric kits. RESULTS: Compared with infusion of SAL, IH infusion increased hepatic glucose production (HGP), and decreased glucose utilization (GU) (P<0.05). The elevation of plasma free fatty acids increased the MDA levels and decreased the GSH-PX activity in the liver and muscle (P<0.01). Sodium salicylate treatment decreased HGP, elevated GU (P<0.05), reduced MDA content by 60% (P<0.01), and increased the GSH-PX activity by 35% (P<0.05). CONCLUSIONS: Short-term elevation of fatty acids induces insulin resistance by enhancing oxidative stress levels in the liver and muscle. The administration of the anti-inflammatory drug sodium salicylate reduces the degree of oxidative stress, therefore improving hepatic and peripheral insulin resistance. IKK-beta and NF-kappa B provide potential pathogenic links to oxidative stress. 展开更多
关键词 free fatty acids sodium salicylate oxidative stress insulin resistance hepatic glucose production
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A Magentoelectric Coefficient Measurement System with a Free-Stress Sample Holder
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作者 Jingjing Lu Xiya Wang +5 位作者 Junhao Wang Yufei Zhou Duo Chen Shibo Wang Maofa Zhang Xiangbin Zeng 《Journal of Minerals and Materials Characterization and Engineering》 2020年第4期330-340,共11页
With less extra stress on the testing sample, a free-stress sample holder was designed to place the sample horizontally. With the free-stress sample holder, a magnetoelectric (ME) coefficient measurement system was de... With less extra stress on the testing sample, a free-stress sample holder was designed to place the sample horizontally. With the free-stress sample holder, a magnetoelectric (ME) coefficient measurement system was developed based on dynamic method. This measurement system has the hardware part and the software part, integrated by the DC magnetic field generation module, the AC magnetic field generation module, the induced ME voltage detecting module and PC software module. Then, a sample of Terfenol-D/PZT/Terfenol-D trilayer was designed and fabricated, and the relationships of its ME coefficient influenced by the DC magnetic field and the frequency of the AC magnetic field were tested using the measurement system. And the results showed that the free-stress sample holder was proven to improve the accuracy of the measurement system by less stress interference. 展开更多
关键词 Magnetoelectric Coefficient Measurement System free-stress Sample Holder
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基于Label-free技术的高州油茶铝胁迫蛋白质组学研究
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作者 程俊森 王溢 +4 位作者 李永泉 魏尚霖 李超楠 姜维 黄润生 《中南林业科技大学学报》 CAS CSCD 北大核心 2023年第8期169-181,共13页
【目的】南方地区拥有大面积的酸性红壤,导致土壤中铝元素多以离子的形式溶出,严重抑制油茶的生长及高产。研究采用Label-free技术探究高州油茶在铝胁迫下的蛋白质组学响应,为揭示高州油茶应答铝胁迫的分子响应机制奠定了理论基础。【... 【目的】南方地区拥有大面积的酸性红壤,导致土壤中铝元素多以离子的形式溶出,严重抑制油茶的生长及高产。研究采用Label-free技术探究高州油茶在铝胁迫下的蛋白质组学响应,为揭示高州油茶应答铝胁迫的分子响应机制奠定了理论基础。【方法】以高州油茶两年生实生苗为试验材料,测定不同浓度铝处理条件下高州油茶叶片部分代谢指标及抗氧化生理相关指标,同时比较对照组(CK)和4 mmol/L铝处理组(GZ4)差异蛋白质的表达。【结果】生理试验结果表明,不同浓度铝胁迫下油茶幼苗都会发生氧化胁迫导致细胞活性氧(ROS)积累,2 mmol/L铝浓度下油茶叶片通过增加渗透调节物质含量和增强多种抗氧化酶活性以清除细胞活性氧,使细胞免受氧化胁迫的损害;而4 mmol/L铝浓度下叶片丙二醛(MDA)含量和脯氨酸(PRO)含量明显升高,积累的活性氧超出了自身所能清除的范围,叶片可溶性糖含量和可溶性蛋白含量显著减少,抗氧化酶活性均有不同程度减弱,油茶正常的生理功能受到抑制。蛋白质组学数据表明,CK组和GZ4组共鉴定到4282个蛋白质,与CK组相比,GZ4处理组有207个蛋白质的表达丰度显著增加,129个蛋白质的表达丰度显著降低。差异表达蛋白质的通路富集和蛋白质互作网络分析结果表明,4 mmol/L铝胁迫下高州油茶主要通过提高谷胱甘肽代谢,增强细胞清除活性氧和自由基负离子的能力缓解铝胁迫造成的氧化损伤;4 mmol/L铝浓度下高州油茶蛋白质合成和光合作用受到明显抑制,抗氧化酶活性减弱可能与细胞供能能力不足有关。【结论】铝胁迫下高州油茶主要通过能量及碳水化合物代谢、氨基酸合成及代谢、生物碱合成、蛋白质加工、卟啉和叶绿素代谢等代谢途径抵抗铝毒。 展开更多
关键词 高州油茶 铝胁迫 蛋白质组学 LABEL-free
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Consumption of Mercury-contaminated Rice Induces Oxidative Stress and Free Radical Aggravation in Rats
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作者 XIU-LING JI GUI-WEN JIN +3 位作者 JIN-PING CHENG WEN-HUA WANG JING LU LI-YA QU 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2007年第1期84-89,共6页
Objective To study the oxidative stress induced by consumption of mercury-contaminated rice in rats, and to assess the possible public health risk of mercury contamination in Wanshan mining area. Methods Sprague Dawle... Objective To study the oxidative stress induced by consumption of mercury-contaminated rice in rats, and to assess the possible public health risk of mercury contamination in Wanshan mining area. Methods Sprague Dawley rats were fed the mercury-contaminated rice produced from Wanshan area for 90 days. The antioxidant status and the free radicals in rat serum were evaluated. Results High mercury accumulation in organs of rats fed the mercury-contaminated rice confirmed the server pollution of mercury in Wanshan mining area. The intensity of electron spin resonance (ESR) signal increased by 87.38% in rats fed the rice from Wanshan compared with that in the control rats fed the rice from Shanghai, suggesting that chronic dietary consumption of rice from mercury mining area could induce an aggravation of free radicals. Feeding the mercury-contaminated rice was associated with significant decreases in the antioxidant enzymatic activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) and concentration of serum nitric oxide (NO), but it had no effect on serum nitric oxide synthase (NOS) activity. Feeding the mercury-contaminated rice raised the level of serum malonyldialdehyde (MDA), indicating the occurrence of oxidative stress. Conclusion The long-term dietary consumption of mercury-contaminated rice induces the aggravation of free radicals and exerts oxidative stress. 展开更多
关键词 Electron spin resonance free radicals MERCURY Oxidative stress RICE
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Oxidative stress and free radicals related diseases of the newborn
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作者 Serafina Perrone Maria Luisa Tataranno +1 位作者 Gemma Stazzoni Giuseppe Buonocore 《Advances in Bioscience and Biotechnology》 2012年第7期1043-1050,共8页
Free radicals (FRs) generation is an unavoidable consequence of the life in an oxygen-rich atmosphere. FRs can be considered a double-edged sword. Beneficial effects of FRs occur at moderate concentrations and involve... Free radicals (FRs) generation is an unavoidable consequence of the life in an oxygen-rich atmosphere. FRs can be considered a double-edged sword. Beneficial effects of FRs occur at moderate concentrations and involve physiological roles in cellular responses to noxia, as in defense against infectious agents, in the function of a number of cellular signaling pathways and the induction of a mitogenic response. The over-production of FRs and the insufficiency of an antioxidant mechanism result in oxidative stress (OS), a deleterious process and important mediator of damage to cell structures and tissues. It occurs at birth in all newborns as a consequence of the hyperoxic challenge after the transition from the hypoxic intrauterine environment to extrauterine life. During the perinatal period, OS can be magnified by others predisposing conditions such as hyperoxia, hypoxia, ischemia, hypoxia-reperfusion, inflammation and high levels of non-protein bound iron. Epidemiological studies linked OS occurring during fetal stages and early infancy with adverse health outcomes later in life, indicating that OS is an early event in the etiology of these chronic diseases. Newborns, especially if preterm, are particularly susceptible to OS and damage due to the increased generation of FRs, the lack of adequate antioxidant protection, and the inability to induce antioxidant defenses during the hyperoxic challenge at birth. This impairment of the oxidative balance has been thought to be the common factor of pathologies grouped together as “free radical disease in the neonate” that include retinopathy of prematurity (which may lead to blindness in severe cases), bronchopulmonary dysplasia (a particularly debilitating pulmonary lesion of the preterm infant), periventricular leukomalacia (an important cause of severe neurodisability) and necrotizing enterocolitis. In this review we discuss in detail these perinatal diseases. Particularly, we analyze the current knowledge about the role of OS in their pathogenesis. 展开更多
关键词 NEWBORN INFANT free RADICALS PERINATAL Diseases OXIDATIVE stress
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常泰长江大桥斜拉索施工期扭转影响分析及防控装置设计研究
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作者 夏鹏飞 康学云 厉勇辉 《现代交通与冶金材料》 CAS 2024年第5期89-94,共6页
常泰长江大桥是世界上最大跨径斜拉桥,主跨跨径为1208 m。斜拉索规格和索力大,施工过程中斜拉索扭转问题突出。本文开展斜拉索扭转对主梁安装控制影响的研究,计算分析表明,斜拉索扭转对斜拉索钢丝应力、斜拉索索力均有一定影响,对主梁... 常泰长江大桥是世界上最大跨径斜拉桥,主跨跨径为1208 m。斜拉索规格和索力大,施工过程中斜拉索扭转问题突出。本文开展斜拉索扭转对主梁安装控制影响的研究,计算分析表明,斜拉索扭转对斜拉索钢丝应力、斜拉索索力均有一定影响,对主梁线形影响显著,斜拉索扭转0.5°,主跨位移变化0.46 m;提出了一种斜拉索张拉防扭转装置及其设计方法,现场应用中斜拉索张拉过程中无扭转现象,施工过程中最大线形误差小于5 cm。 展开更多
关键词 斜拉桥 平行钢丝斜拉索 扭转 无应力长度 防扭转装置
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南、北五味子蛋白抗氧化活性和对HepG2细胞氧化应激损伤的修复作用 被引量:2
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作者 周泓妍 郑怡 +5 位作者 王海东 曹珺 张涵 张红印 李光哲 严铭铭 《食品与发酵工业》 CAS CSCD 北大核心 2024年第7期51-60,共10页
采用碱提酸沉法提取南五味子蛋白(Schisandra sphenanthera protein,SSP)和北五味子蛋白(Schisandra chinensis protein,SCP),并测定其体外清除自由基能力、还原能力和对H_(2)O_(2)诱导的HepG2细胞氧化损伤的修复作用。采用CCK-8法检测... 采用碱提酸沉法提取南五味子蛋白(Schisandra sphenanthera protein,SSP)和北五味子蛋白(Schisandra chinensis protein,SCP),并测定其体外清除自由基能力、还原能力和对H_(2)O_(2)诱导的HepG2细胞氧化损伤的修复作用。采用CCK-8法检测细胞增殖率,荧光检测胞内活性氧水平,酶联免疫吸附法检测细胞氧化应激产物和抗氧化物酶系活性。结果表明,SSP清除自由基和还原能力均优于SCP,SSP与SCP都能对H_(2)O_(2)诱导HepG2造成的细胞生长抑制起到修复作用(P<0.05),显著降低胞内活性氧、丙二醛水平(P<0.05),显著提高超氧化物歧化酶、过氧化氢酶、谷胱甘肽过氧化物酶和谷胱甘肽的水平(P<0.05),且SSP对H_(2)O_(2)诱导的HepG2氧化应激损伤修复能力优于SCP。综上,2种五味子蛋白中SSP更适合应用于抗氧化功能性食品或保健食品工业中。 展开更多
关键词 蛋白 自由基清除 氧化应激 HEPG2细胞 抗氧化
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插入道岔施工对运营高速道岔锁定轨温变化影响试验
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作者 谢铠泽 代玮武 +2 位作者 李义强 杨观星 朱学伟 《北京交通大学学报》 CAS CSCD 北大核心 2024年第1期66-73,共8页
为研究插入道岔施工(Turnout Inserting Construction,TIC)对既有高速道岔锁定轨温(StressFree Rail Temperature of Existing high-speed Turnout,SFRTET)的影响,提出基于双向应变法的锁定轨温变化测试方案,推导不同因素影响下的锁定... 为研究插入道岔施工(Turnout Inserting Construction,TIC)对既有高速道岔锁定轨温(StressFree Rail Temperature of Existing high-speed Turnout,SFRTET)的影响,提出基于双向应变法的锁定轨温变化测试方案,推导不同因素影响下的锁定轨温变化测量原理,确定监测数据的处理方法,并开展道岔锁定轨温变化现场试验研究.研究结果表明:基于锁定轨温变化监测方法确定的传感器安装时轨温与实测数据差异仅1.4%,验证了测试方案的合理性和数据处理方法的正确性;高速道岔的锁定轨温会受插入道岔各工序施工的影响,其在轨道结构拆除、轨道结构施工、道岔形位精调和工电联调3个工序中表现出显著的动态变化特征,即锁定轨温经历多次循环变化才达到稳定状态;既有高速道岔锁定轨温受侧股钢轨重新焊接施工影响最为显著,尤其是靠近焊接位置的侧股钢轨,其锁定轨温变化达12.87℃,建议侧股钢轨重新焊接工序尽可能选择在轨温接近既有道岔原锁定轨温时开展. 展开更多
关键词 铁道工程 高速道岔 锁定轨温 运营铁路 测试原理
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基于无应力状态法的异形钢箱拱塔施工过程线形控制
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作者 杨小波 韩旭 《公路交通科技》 CAS CSCD 北大核心 2024年第7期118-125,共8页
为进一步优化异形钢箱拱塔施工及安装方法,以某异形斜拉桥中采用的双肢非一致倾斜拱形桥塔为工程案例,考虑支架对结构线形的影响,分析了桥塔施工过程线形变化。针对钢箱桥塔内部板件变化复杂且规律性低、传统建模方法效率低下的问题,使... 为进一步优化异形钢箱拱塔施工及安装方法,以某异形斜拉桥中采用的双肢非一致倾斜拱形桥塔为工程案例,考虑支架对结构线形的影响,分析了桥塔施工过程线形变化。针对钢箱桥塔内部板件变化复杂且规律性低、传统建模方法效率低下的问题,使用插值原理生成坐标并对号入座到节点逻辑编号,节点逻辑编号中自带单元信息,单元可以通过循环快速生成,形成了复杂钢箱结构快速建模方法;针对传统正装法在计算闭环结构时常发生的单元畸变导致算法不收敛现象,将无应力状态法与正装法相结合,解释了传统正装方法失效的原理,提出一种改进的闭环结构施工过程模拟的分析方法——无应力正装法,运用该方法分析了支架上的闭环结构施工过程中的3种线形方案,以合龙为目标精确计算了主塔结构在施工过程中的三向控制线形,顺桥向、横桥向和竖向最大变形分别为16,2 cm和9 cm,两肢间三向线形偏差分别为5,3.5,5 cm,同时计算了桥塔节段的安装线形,作为实际桥塔施工安装的重要定位依据,安装线形最大矢量位移值为2.8 cm,最终节段安装线形恰好落在零位置处,实现了合龙段的零偏差安装。无应力状态法在异形钢箱拱塔施工过程线形控制中的应用展示了其在保证施工精度和效率方面的优势,给桥塔安装提供了重要的定位基准。 展开更多
关键词 桥梁工程 施工过程模拟 线形分析 无应力状态 闭环结构 快速建模
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平行钢丝斜拉索更换施工新索无应力长度确定方法研究
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作者 余忠儒 邓力文 +1 位作者 蒋建军 单德山 《桥梁建设》 EI CSCD 北大核心 2024年第5期148-155,共8页
为准确确定平行钢丝斜拉索更换施工新索无应力长度,基于悬链线法和无应力状态法,并结合斜拉索索力、锚点间距、斜拉索原始加工长度和实际锚固位置等数据,综合提出5种针对不同数据场景下的平行钢丝斜拉索新索无应力长度快速计算方法。以... 为准确确定平行钢丝斜拉索更换施工新索无应力长度,基于悬链线法和无应力状态法,并结合斜拉索索力、锚点间距、斜拉索原始加工长度和实际锚固位置等数据,综合提出5种针对不同数据场景下的平行钢丝斜拉索新索无应力长度快速计算方法。以攀枝花炳草岗大桥为背景,采用5种方法计算该桥新索无应力长度,分析其合理性,并进一步提出6项新索无应力长度复核计算准则。结果表明:在充分研判炳草岗大桥基础资料并对照6项复核计算准则的合理性后,基于无应力状态法,并结合旧索加工总长和实测锚具伸出量,准确给出了新索无应力长度。该桥新索张拉锚固完成后,塔、梁端实际锚固位置合理、可控,成功解决了其基础资料混乱、斜拉索锚固位置不当的问题。 展开更多
关键词 斜拉桥 平行钢丝斜拉索 斜拉索更换 无应力长度 悬链线法 计算方法
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无应力状态法在半穿式连续钢桁架桥设计和施工中的应用 被引量:1
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作者 胡健 《工程技术研究》 2024年第3期71-73,共3页
盐城市盐渎路大桥主桥是超大宽度的半穿式连续钢桁架结构,受力复杂,构件繁多,该桥在设计和施工中运用无应力状态法,成桥后获得了与设计目标相一致的内力和线形。文章首先介绍了桥梁概况,然后概述了无应力状态法,在此基础上进行了桥梁无... 盐城市盐渎路大桥主桥是超大宽度的半穿式连续钢桁架结构,受力复杂,构件繁多,该桥在设计和施工中运用无应力状态法,成桥后获得了与设计目标相一致的内力和线形。文章首先介绍了桥梁概况,然后概述了无应力状态法,在此基础上进行了桥梁无应力构形的确定,最后提出了桥梁施工方法,以供参考。 展开更多
关键词 无应力状态法 半穿式钢桁架 桥梁设计 桥梁施工
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压力性尿失禁患者经阴道无张力尿道中段悬吊术后排尿功能恢复情况及其相关影响因素
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作者 孔丽丽 于丽君 +2 位作者 刘硕 陈一依 范颖 《新乡医学院学报》 CAS 2024年第8期750-754,共5页
目的探讨压力性尿失禁(SUI)患者经阴道无张力尿道中段悬吊术后排尿功能恢复情况及其相关影响因素。方法选择2018年10月至2023年10月于首都医科大学附属北京康复医院接受经阴道无张力尿道中段悬吊术的112例SUI患者为研究对象。记录患者... 目的探讨压力性尿失禁(SUI)患者经阴道无张力尿道中段悬吊术后排尿功能恢复情况及其相关影响因素。方法选择2018年10月至2023年10月于首都医科大学附属北京康复医院接受经阴道无张力尿道中段悬吊术的112例SUI患者为研究对象。记录患者术后排尿功能恢复情况,依据术后排尿功能恢复时间将术后恢复至正常排尿时间≤3 d的患者纳入快速恢复组,术后恢复至正常排尿时间>3 d的患者纳入非快速恢复组。比较2组患者的年龄、体质量指数、是否绝经、经阴道分娩史、分娩次数、疾病严重程度、合并高血压、合并糖尿病、盆腔器官脱垂史、最大尿流率、术后尿潴留、术前膀胱残余尿量、膀胱最大容量、血红蛋白(Hb)水平、白细胞(WBC)计数、红细胞(RBC)计数及血小板(PLT)计数等临床资料,应用多因素logistic回归分析SUI患者术后排尿功能恢复的影响因素。结果112例SUI患者术后排尿功能恢复时间为1~15(4.10±0.78)d,其中64例(57.14%)术后排尿功能恢复时间≤3 d,48例(42.86%)术后排尿功能恢复时间>3 d。非快速恢复组绝经、有经阴道分娩史、有盆腔器官脱垂史、术后尿潴留患者占比均显著高于快速恢复组,最大尿流率显著低于快速恢复组(P<0.01);2组患者的年龄、体质量指数、分娩次数、术前膀胱残余尿量、膀胱最大容量、Hb水平、WBC计数、RBC计数、PLT计数、疾病严重程度、合并高血压占比、合并糖尿病占比比较差异无统计学意义(P>0.05)。多因素logistic回归分析显示,绝经、有经阴道分娩史、盆腔器官脱垂史、术后尿潴留及最大尿流率是SUI患者术后排尿功能恢复的影响因素(P<0.05)。结论SUI患者经阴道无张力尿道中段悬吊术后排尿功能恢复情况并不理想,绝经、有经阴道分娩史、盆腔器官脱垂史、术后尿潴留及最大尿流率是SUI患者术后排尿功能恢复的影响因素。 展开更多
关键词 压力性尿失禁 阴道无张力尿道中段悬吊术 排尿功能 影响因素
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薄壁工件多点磁力辅助夹具设计研究
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作者 郝清龙 沈帅祺 许云 《组合机床与自动化加工技术》 北大核心 2024年第7期142-145,149,共5页
航空发动机叶片等薄壁工件是典型的弱刚性工件,具有壁厚薄、刚性差、型面复杂以及材料难加工等特点,在加工过程中极易产生弯曲、扭转变形导致工件超差。针对叶片类薄壁零件加工过程中弱刚性导致的变形及复杂曲面难以支撑问题,首先,对现... 航空发动机叶片等薄壁工件是典型的弱刚性工件,具有壁厚薄、刚性差、型面复杂以及材料难加工等特点,在加工过程中极易产生弯曲、扭转变形导致工件超差。针对叶片类薄壁零件加工过程中弱刚性导致的变形及复杂曲面难以支撑问题,首先,对现有相变材料辅助夹具进行了分析,并提出了薄壁零件的无应力辅助支撑原理;然后,基于无应力辅助支撑原理及复杂曲面离散化原则设计了一种用于叶片类薄壁工件辅助支撑的多点磁力辅助夹具,并对其装夹变形以及辅助支撑能力进行了理论分析和试验研究;最后,基于该辅助支撑夹具对叶片进行了磨削加工试验,验证了所设计的辅助夹具在弱刚性工件刚性增强以及加工变形控制方面的优越性。 展开更多
关键词 叶片加工 变形控制 曲面装夹 无应力辅助装夹 多点磁力辅助夹具
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考虑磁畴偏转的无取向硅钢应力各向异性磁致伸缩特性模拟
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作者 贲彤 孔玉琪 +2 位作者 陈龙 方敏 张献 《电工技术学报》 EI CSCD 北大核心 2024年第4期935-946,共12页
无取向硅钢铁心的电磁振动是电机噪声的根本来源,采用夹件固定铁心可有效抑制其振动,但夹紧力施加不当会加剧铁心振动,原因为应力使无取向硅钢的磁畴取向发生偏转而引起磁致伸缩形变增大,形成应力各向异性。因此,为了获得准确的应力加... 无取向硅钢铁心的电磁振动是电机噪声的根本来源,采用夹件固定铁心可有效抑制其振动,但夹紧力施加不当会加剧铁心振动,原因为应力使无取向硅钢的磁畴取向发生偏转而引起磁致伸缩形变增大,形成应力各向异性。因此,为了获得准确的应力加载方法,需建立考虑磁畴偏转的无取向硅钢应力各向异性磁致伸缩模型。首先,求解自由能模型并计算能量极值点的分布,模拟无取向硅钢在磁场和应力作用下的磁畴偏转路径;其次,用磁晶各向异性能、应力各向异性能以及磁场能贡献的总和表示无磁滞磁化强度,将自由能模型与考虑磁滞的磁致伸缩模型相结合,通过无取向硅钢磁致伸缩特性测试获取模型参数并进行参数依赖性分析;最后,模拟应力与磁场作用下不同磁化方向的无取向硅钢的磁滞特性和磁致伸缩特性,通过仿真结果与实验结果的对比验证了该模型的准确性。结果表明,应力的增大会使无取向硅钢磁致伸缩应变值减小,同一应力下,磁致伸缩应变的大小会随磁化角度的增大而增大,该文所提出的应力各向异性磁致伸缩模型可以有效模拟此种变化规律。 展开更多
关键词 应力各向异性 磁畴偏转 自由能模型 磁致伸缩模拟
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不同术式治疗腹股沟疝患者的效果
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作者 褚晓东 《中国民康医学》 2024年第8期47-50,共4页
目的:比较腹腔镜经腹腹膜前腹股沟疝修补术(TAPP)、腹腔镜全腹腹膜外腹股沟疝修补术(TEP)与传统无张力疝修补术治疗腹股沟疝患者的效果。方法:选取2021年3月至2023年1月该院收治的141例腹股沟疝患者进行前瞻性研究,依据随机数字表法将... 目的:比较腹腔镜经腹腹膜前腹股沟疝修补术(TAPP)、腹腔镜全腹腹膜外腹股沟疝修补术(TEP)与传统无张力疝修补术治疗腹股沟疝患者的效果。方法:选取2021年3月至2023年1月该院收治的141例腹股沟疝患者进行前瞻性研究,依据随机数字表法将其分为传统组、腹腔镜A组、腹腔镜B组各47例。传统组行无张力疝修补术治疗,腹腔镜A组行TAPP治疗,腹腔镜B组行TEP治疗,比较三组围术期指标水平、术后疼痛程度[视觉模拟评分法(VAS)]评分、手术前后应激指标水平[皮质醇(Cor)、去甲肾上腺素(NE)、促肾上腺皮质激素(ACTH)]水平、术后1周内并发症发生率和随访3个月的复发率。结果:腹腔镜A、B组手术时间、肠道功能恢复时间均长于传统组,下床活动时间均短于传统组,术中失血量均少于传统组,差异有统计学意义(P<0.05);腹腔镜B组手术时间、下床活动时间均短于腹腔镜A组,差异有统计学意义(P<0.05);腹腔镜A、B组术中失血量、肠道功能恢复时间比较,差异均无统计学意义(P>0.05);腹腔镜A、B组术后1 d、3 d和1周VAS评分比较,差异均无统计学意义(P>0.05);术后3d,三组血清ACTH、NE、Cor水平均高于术前1 d,但腹腔镜B组<腹腔镜A组<传统组,差异有统计学意义(P<0.05);三组并发症发生率、复发率比较,差异均无统计学意义(P>0.05)。结论:TEP、TAPP治疗腹股沟疝患者下床活动时间均短于传统无张力疝修补术治疗,术中失血量均少于传统无张力疝修补术治疗;TEP治疗腹股沟疝患者的手术时间、下床活动时间均短于TAPP治疗,应激指标水平均低于TAPP治疗和传统无张力疝修补术治疗,三种术式各有利弊。 展开更多
关键词 腹腔镜经腹腹膜前腹股沟疝修补术 腹腔镜全腹腹膜外腹股沟疝修补术 无张力疝修补术 腹股沟疝 应激 并发症
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