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A frequency-adapted optimal-weighted method of array interference striations
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作者 DA Lianglong XU Guojun +1 位作者 ZHAO Jianxin HAN Mei 《Chinese Journal of Acoustics》 CSCD 2017年第3期313-327,共15页
Considering the filter properties of the long horizontal line array (HLA) to the sound field modes, we established an adaptive optimal method to design HLA weights, which can change the filter pass band with the fre... Considering the filter properties of the long horizontal line array (HLA) to the sound field modes, we established an adaptive optimal method to design HLA weights, which can change the filter pass band with the frequency. Using the normal modes theory and combining with the feature of the sound field HLA beamformer, and analyzing the differences of definition and slope in the LOFAR (Low Frequency Analysis Recording) spectrogram between the single-hydrophone and the beamformer, a frequency-adapted optimal-weighted (FAOW) estimate method was obtained by solving a quadratic optimization model with linear equality constraints. The numerical simulation and the experimental data analysis indicated that we can obtain the beamformer signal with the designed optimal array weight which was made up by the Surface-Reflected Bottom-Reflected modes or Non-Surface-Reflected Bottom-Reflected modes. The slope of striations in the signal spectrogram fitted well with the theoretical analysis. 展开更多
关键词 A frequency-adapted optimal-weighted method of array interference striations HLA mode
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Ion resonance causes striations in electronegative rf glow discharges
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《Science Foundation in China》 CAS 2016年第4期33-33,共1页
With the support by the National Natural Science Foundation of China,Dr Liu Yongxin(刘永新)and his coworkers at the Key Laboratory of Materials Modification by Laser,Ion,and Electron Beams(Ministry of Education),Schoo... With the support by the National Natural Science Foundation of China,Dr Liu Yongxin(刘永新)and his coworkers at the Key Laboratory of Materials Modification by Laser,Ion,and Electron Beams(Ministry of Education),School of Physics and Optoelectronic Technology,Dalian University of Technology,observed,for the first time,the self-organized striated structures of the plasma emission in 展开更多
关键词 TIME 刘永新 Ion resonance causes striations in electronegative rf glow discharges
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Femtosecond laser shockwave peening ablation in liquids for hierarchical micro/nanostructuring of brittle silicon and its biological application 被引量:9
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作者 Dongshi Zhang Liang-Chun Wu +2 位作者 Masashi Ueki Yoshihiro Ito Koji Sugioka 《International Journal of Extreme Manufacturing》 EI 2020年第4期29-47,共19页
This paper presents a new technique,termed femtosecond laser shock peening ablation in liquids(fs-LSPAL),which can realize simultaneous crack micro/nanomanufacturing and hierarchical micro/nanolaser ablation,giving ri... This paper presents a new technique,termed femtosecond laser shock peening ablation in liquids(fs-LSPAL),which can realize simultaneous crack micro/nanomanufacturing and hierarchical micro/nanolaser ablation,giving rise to the formation of diverse multiscale hierarchical structures,such as macroporous ratcheted structures and enéchelon microfringes decorated with parabolic nanoripples.Through analysis of surface morphologies,many phenomena have been confirmed to take place during fs-LSPAL,including enéchelon cracks,nanostriation,ripple densification,crack branching,and selective formation of high spatial frequency laser-induced periodic surface structures of 100–200 nm in period.At a high laser power of 700 mW,fs-LSPAL at scanning speeds of 0.2 mm s^-1 and 1 mm s^-1 enables the generation of height-fluctuated and height-homogeneous hierarchical structures,respectively.The height-fluctuated structures can be used to induce‘colony’aggregates of embryonic EB3 stem cells.At 200 mW,fs-LSPAL at 1 mm s^-1 is capable of producing homogeneous tilt macroporous structures with cracked structures interleaved among them,which are the synergistic effects of bubble-induced light refraction/reflection ablation and cracks.As shown in this paper,the conventional laser ablation technique integrated with its self-driven unconventional cracking under extreme conditions expands the horizons of extreme manufacturing and offers more opportunities for complex surface structuring,which can potentially be used for biological applications. 展开更多
关键词 femtosecond laser shock peening ablation SHOCKWAVES MACROPOROUS enéchelon crack striations brittle materials stem cell culture
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Optimization of Abrasive Water Jet Cutting of Ductile Materials 被引量:1
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作者 Asif IQBAL Naeem U DAR Ghulam HUSSAIN 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2011年第1期88-92,共5页
Full factorial design of experiments was developed in order to investigate the effects of jet pressure, abrasive mixing rate, cutting feed, and plate thickness upon three response variables, surface finish of cutting ... Full factorial design of experiments was developed in order to investigate the effects of jet pressure, abrasive mixing rate, cutting feed, and plate thickness upon three response variables, surface finish of cutting wear zone, percentage proportion of striation free area, and maximum width of cut. The set of sixteen experiments was performed on each of the following two ductile materials: AISI 4340 (high strength low alloy steel, hardened to 49HRc) and Aluminum 2219. Analysis of Variance (ANOVA) was performed on experimental data in order to determine the significance of effects of different parameters on the performance measures. It was found that cutting feed and thickness were highly influential parameters, while abrasive mixing rate is influential upon surface roughness only. Strong interaction was found between jet pressure and workpiece material. Multi-criteria numerical optimization was performed in order to simultaneously maximize/minimize different combinations of performance measures. 展开更多
关键词 abrasive jet cutting ductile metals material processing striations OPTIMIZATION
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Nonlinear phenomena in dielectric barrier discharges: pattern, striation and chaos 被引量:1
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作者 Jiting OUYANG Ben LI +1 位作者 Feng HE Dong DAI 《Plasma Science and Technology》 SCIE EI CAS CSCD 2018年第10期23-50,共28页
The nonlinear phenomenon is very popular in dielectric barrier discharge (DBD) plasmas. There are at least three kinds of spatial and temporal nonlinear phenomena appearing synchronously or asynchronously in DBDs, i... The nonlinear phenomenon is very popular in dielectric barrier discharge (DBD) plasmas. There are at least three kinds of spatial and temporal nonlinear phenomena appearing synchronously or asynchronously in DBDs, i.e. self-organized patterns, striations and chaos. This paper describes the recent research and progress in understanding the nature of these nonlinear phenomena. Patterns are macroscopic structures with certain spatial and/or temporal periodicities generated through self- organization of microscopic parameters. The physics of patterns in DBDs is mainly associated with lateral dynamic behaviors or the lateral non-local effect of charged particles resulting in the lateral development or non-uniformity of discharge. Striations are ionization waves with unique properties determined by transport phenomena, ionization processes and electron kinetics in current-carrying plasmas. The physics of striations in DBDs is mainly associated with the advances in non-local electron kinetics in spatially inhomogeneous plasmas. Chaos is a kind of random and non-periodic phenomenon occunfng in a determined dynamic system, following a series of certain rules while exhibiting random locomotion, and is regarded as an intrinsic and ubiquitous phenomenon in a nonlinear dynamic system. An evolution trajectory including period-doubling bifurcation to chaos was observed in DBDs or DBD-derived plasmas. In a common sense, it is believed that the formation of all the three nonlinear phenomena in a DBD system should be related to the non-local transversal and/or longitudinal dynamics of space charges (i.e. non-local effect) or the localized electric field interaction. Future work is still needed on the underlying physics and should be directed to pursuing the unification of these nonlinear phenomena in DBD. 展开更多
关键词 nonlinear phenomenon dielectric barrier discharge PATTERN STRIATION CHAOS
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Investigation of Anode Striation in 34”VGA Shadow Mask PDP 被引量:1
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作者 屠彦 姜有燕 +2 位作者 杨兰兰 张雄 王保平 《Plasma Science and Technology》 SCIE EI CAS CSCD 2007年第4期474-479,共6页
A macro-cell was used to study the phenomenon of anode striation on a 34 VGA Shadow Mask Plasma Display Panel (SMPDP). The breakdown process in the sustaining period of the macro-cell was taken by an Intensified Cha... A macro-cell was used to study the phenomenon of anode striation on a 34 VGA Shadow Mask Plasma Display Panel (SMPDP). The breakdown process in the sustaining period of the macro-cell was taken by an Intensified Charge Coupled Device(ICCD) with narrow band filters. The mechanism of formation and evolution of the anode striation on SMPDP were investigated. The influence of the width of the electrode, the sustaining voltage, sustaining frequency and the voltage of the shadow mask on the anode striation was also studied. The results showed that the width of the electrodes, the sustaining voltage and frequency had a strong influence on the anode striation. The voltage of the shadow mask, however, hardly affected the anode striation, the firing voltage or the sustaining voltage. 展开更多
关键词 shadow mask plasma display panel discharge characteristics anode striation
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Evolution of Striation in Pulsed Glow Discharges 被引量:1
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作者 刘远野 何锋 +1 位作者 赵晓菲 欧阳吉庭 《Plasma Science and Technology》 SCIE EI CAS CSCD 2016年第1期30-34,共5页
In this work,striations in pulsed glow discharges are studied by experiments and Particle-In-Cell/Monte Carlo Collision(PIC/MCC)simulation.The spatio-temporal evolution of the potential and the electron energy durin... In this work,striations in pulsed glow discharges are studied by experiments and Particle-In-Cell/Monte Carlo Collision(PIC/MCC)simulation.The spatio-temporal evolution of the potential and the electron energy during the discharge are analyzed.The processes of striation formation in pulsed glow discharges and dielectric barrier discharges(DBD)are compared.The results show that the mechanisms of striation in pulsed DC discharge and DBD are similar to each other.The evolution of electron energy distribution function before and after the striation formation indicates that the striation results from the potential well of the space charge.During a pulsed breakdown,the striations are formed one by one towards the anode in a weak field channel.This indicates that the formation of striations in a pulsed discharge depends on the flow of modulated electrons. 展开更多
关键词 striation pulsed discharge PIC/MCC
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Growth Defects in Langasite Crystals Observed with White Beam Synchrotron Radiation Topography
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作者 Wang Xuping Wang Jiyang Hu Xiaobo Zhang Jianxiu Zhao Hongyang Huang Wanxia Zhu Peiping 《Journal of Rare Earths》 SCIE EI CAS CSCD 2006年第z1期159-161,共3页
Langasite single crystal was grown by the Czochralski method and its perfection was assessed by white beam synchrotron radiation topography. It is found that the growth core and the growth striations are the primary g... Langasite single crystal was grown by the Czochralski method and its perfection was assessed by white beam synchrotron radiation topography. It is found that the growth core and the growth striations are the primary growth defects and they show strong X-ray kinematical contrast in the topographs. Another typical defect in LGS crystal is dislocation. The formation mechanisms of these growth defects in LGS crystals were discussed. 展开更多
关键词 LANGASITE (LGS crystal) GROWTH STRIATION GROWTH core DISLOCATION
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CYCLIC DEFORMATION OF COARSE GRAINED POLYCRYSTALLINE PURE Al——Ⅱ.FRACTURE SURFACE MORPHOLOGY
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作者 XIA Yuebo WANG Zhongguang State Key Laboratory for Fatigue and Failure of Materials,Institute of Metal Research,Academia Sinica,Shenyang,China 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 1992年第5期330-335,共6页
SEM photos for very coarse grained and high ductile polycrystalline pure Al show following characteristics:A few fracture sources are concentrated,the crack propagates in fan-shape near them,and the fatigue striations... SEM photos for very coarse grained and high ductile polycrystalline pure Al show following characteristics:A few fracture sources are concentrated,the crack propagates in fan-shape near them,and the fatigue striations are cyclic cleavage facets.Each striation consists of a wide cleavage facet and a narrow cleavage stage.Those stages often blunt due to plastic deformation.The fatigue striations are clear and continual,and distribute over whole zone of stage Ⅱ crack propagation.Two kinds of fatigue striations form in different levels,are conjoined by a“twisted baked piece of pastry”band.The secondary crack along the fatigue striations was observed frequently.Some of them have already developed into secondary macrocracks and secondary fatigue striations were found clearly on secondary fracture sur- face.The fracture surface can be divided into two parts,initiation and propagation zone of the crack,however,no statical-fracture zone was observed.The mechanism to form striations was preliminarily discussed. 展开更多
关键词 fatigue crack AL fatigue striation secondary crack cleavage tongue
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Formation and destruction of striation plasmas in helium glow discharge at medium pressures
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作者 Hailong ZHU Qixiang HUANG +2 位作者 Yifan WU Yurui LI Kechang REN 《Plasma Science and Technology》 SCIE EI CAS CSCD 2022年第5期176-182,共7页
The striation plasmas are usually generated within a positive column of glow discharge,where rich and complex physical interactions are involved,especially,in the medium or high pressures.Along these lines,our work ai... The striation plasmas are usually generated within a positive column of glow discharge,where rich and complex physical interactions are involved,especially,in the medium or high pressures.Along these lines,our work aims to thoroughly investigate the formation and destruction of helium striation plasmas at kPa level pressures.The characteristics of the helium striation plasmas,and especially the optical emission properties are explored.The emission lines of 706.52 nm and391.44 nm related to the energetic electrons and the high-energy metastable helium atoms respectively,were focused on in this work.The formation of striation plasmas in a helium glow discharge,is mainly associated with the instability originating from the stepwise ionization of high-energy metastable state atoms,Maxwellization of the electron distribution functions and gas heating.Additionally,the destruction effect of helium striation plasmas is of great significance when a small amount of nitrogen or oxygen is mixed into the discharge plasmas.The reduction of the mean electron energy and the consumption of the high-energy metastable helium atoms are considered as the underlying reasons for the destruction of striation plasmas. 展开更多
关键词 striation plasmas medium pressures atomic emission spectroscopy helium discharge metastable atoms ionization wave
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The Representation of a Broadband Vector Field
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作者 任群 Jean Pierre Hermand 朴胜春 《Journal of Marine Science and Application》 2011年第4期495-501,共7页
Compared to a scalar pressure sensor, a vector sensor can provide a higher signal-to-noise ratio (SNR) signal and more detailed intbrmation on the sound field. Study on vector sensors and their applications have bec... Compared to a scalar pressure sensor, a vector sensor can provide a higher signal-to-noise ratio (SNR) signal and more detailed intbrmation on the sound field. Study on vector sensors and their applications have become a hot topic. Research on the representation of a vector field is highly relevant for extending the scope of vector sensor technology. This paper discusses the range-frequency distribution of the vector field due to a broadband acoustic source moving in a shallow-water waveguide as the self noise of a surface ship, and the vector extension of the waveguide impulse response measured over a limited frequency range using an active source of known waveform. From theory analysis and numerical simulation, the range-frequency representation of a vector field exhibits an interference structure qualitatively similar to that of the corresponding pressure field but, being quantitatively different, provides additional information on the waveguide, especially through the vertical component. For the range-frequency representation, physical quantities that can better exhibit the interference characteristics of the wavegaide are the products of pressure and particle velocity and of the pressure and pressure gradient. An image processing method to effectively detect and isolate the individual striations from an interference structure was reviewed briefly. The representation of the vector impulse response was discussed according to two different measurement systems, also known as particle velocity and pressure gradient. The vector impulse response representation can not only provide additional information from pressure only but even more than that of the range-frequency representation. 展开更多
关键词 acoustic waveguide vector field range-frequency interference structure striation processing impulse response normal mode
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Effect of Wall Charge on Striation in Plasma Display Cells
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作者 何锋 欧阳吉庭 +3 位作者 曹菁 冯硕 缪劲松 王建琪 《Plasma Science and Technology》 SCIE EI CAS CSCD 2007年第2期198-201,共4页
Different configurations and driving voltages have been employed to investigate the effect of the wall charge on the striations in macroscopic plasma display panel (PDP) cells. The experimental results show that a d... Different configurations and driving voltages have been employed to investigate the effect of the wall charge on the striations in macroscopic plasma display panel (PDP) cells. The experimental results show that a discharge channel near the dielectric layer is indispensable to striation occurring in the anode area during a discharge, while the pre-accumulated charge on the dielectric layer and the surface state are not important. The origin of the striation is related only to the physical process in the cell. The dielectric layer acts as a charge collector during a PDP discharge. 展开更多
关键词 STRIATION wall charge plasma display panel
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A Statistical Model of Quantitative Relationship between Striation Spacings and Fatigue Crack Growth Rates
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作者 杨京俊 柯伟 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 1989年第6期407-411,共5页
Fatigue crack growth experiments were per- formed on A1 alloy LD 10 and Ti-6A1-4V alloy. Fatigue striation spacings and the deviation angles between the direction of micro-crack growth and that of macro-crack growth w... Fatigue crack growth experiments were per- formed on A1 alloy LD 10 and Ti-6A1-4V alloy. Fatigue striation spacings and the deviation angles between the direction of micro-crack growth and that of macro-crack growth were quanti- tatively measured on fracture surface using scanning electron microscope. A statistical model of the relationship between striation spacings and fatigue crack propagation rates was developed on the basis of a statistical analysis of the deviation angles, Good agreement between experimental results and theoretical results calculated with the present model was obtained. 展开更多
关键词 striation spacing deviation angle fatigue crack growth
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Fault slip and modern tectonic stress field in and around Kunming basin
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作者 荆振杰 杜义 谢富仁 《Acta Seismologica Sinica(English Edition)》 CSCD 2008年第3期233-242,332,共11页
Kunming basin is a Cenozoic faulted basin under the control of mainly SN-trending active faults. In and around the basin, there are a total of eight major active faults. Seismo-geological survey and fault slip observa... Kunming basin is a Cenozoic faulted basin under the control of mainly SN-trending active faults. In and around the basin, there are a total of eight major active faults. Seismo-geological survey and fault slip observation show that the SN- and NE-trending active faults are mostly sinistral strike-slip faults, while the NW-trending faults are mostly dextral strike-slip faults. Using stress tensor inversion method with 706 active fault striation data at 22 measurement sites, we determined tectonic stress field of the study area. The result shows that modern tectonic stress field in and around Kunming basin is characterized by NNW-SSE compression, ENE-WSW extension, and strike-slip stress regimes. The maximum principal compressional stress (σ1) is oriented 335o;o, with an average dip angle of 21°; the minimum (σ3) is oriented 44o;3o, with an average dip angle of 14°, and the intermediate (σ2) has a high, or nearly vertical, dip angle. The inversion result from fault slip data is consistent with the result from focal mechanism solutions. 展开更多
关键词 Kunming basin fault striation tectonic stress field
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Analysis of Striation Formation and Suppression Strategy on Upper Edge of Cutting Surface in Laser Cutting
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作者 Chao Li Dengfei You 《World Journal of Engineering and Technology》 2018年第1期201-213,共13页
Metal laser cutting belongs to mature laser material processing technologies in industry applications. However, without understanding of the mechanism underlying the overall process, the improvement of the cutting qua... Metal laser cutting belongs to mature laser material processing technologies in industry applications. However, without understanding of the mechanism underlying the overall process, the improvement of the cutting quality is restricted. In this paper, an instantaneous melt removal model is presented to describe the process of material removal and striation formation. In the temperature field calculation, melted metal layer is removed when it grows to an assumed thickness. The effects of cutting parameters including cutting speed, gas pressure and laser power on the shape of striation are discussed. A novel method of getting striation free cutting surface is presented. Finally, laser cutting experiments of mild steel is conducted to validate the model. The striation variation trend can be well predicted by the model presented here and the disagreement may be caused by the coupling effect of cutting speed and critical thickness value. 展开更多
关键词 Fusion CUTTING STRIATION Instantaneous Removal Laser Power Modulation
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Study on the Role of Supersonic Nozzle in Fiber Laser Cutting of Stainless Steel
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作者 Yijun Zhou Jilan Kong Jin Zhang 《Materials Sciences and Applications》 2017年第1期85-93,共9页
Striation-free laser cutting, especially for thick section steel, is hard to obtain due to several factors. The inside shape of the gas nozzle is considered to be one of the most vital factors in striation-free fiber ... Striation-free laser cutting, especially for thick section steel, is hard to obtain due to several factors. The inside shape of the gas nozzle is considered to be one of the most vital factors in striation-free fiber laser cutting. 0.8 mm normal nozzle and a supersonic nozzle are used to cut 0.8 mm AISI316L stainless steel (022Cr17Ni12Mo2) separately. The orthogonal experiment takes nozzle standoff distance, cutting speed, Laser power and gas pressure as its impacting factors. The same orthogonal table is adopted in different condition, using normal nozzle and using supersonic nozzle. In the mean time, Ar gas is used as assisted cutting gas in the experiment. The data from this experiment show that supersonic nozzle seems to be a strong helper for fiber laser cutting. Feed rate’s effect seems stable and inconspicuous under the condition of using supersonic nozzle. 展开更多
关键词 Fiber Laser CUTTING STAINLESS Steel STRIATION SUPERSONIC NOZZLE
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A Study on Application of Fractal Theory in Examination of Striation Marks
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作者 WANG Bing-cheng JING Chang 《International Journal of Plant Engineering and Management》 2005年第4期249-254,共6页
Use scissors and cutting pliers to produce some striation marks. The data collection apparatus is used to collect the surface data of such marks produced by scissors and cutting pliers, and then get the profile curve ... Use scissors and cutting pliers to produce some striation marks. The data collection apparatus is used to collect the surface data of such marks produced by scissors and cutting pliers, and then get the profile curve that is vertical to the surface of striation marks. In tha application of fractal theory, the fractal dimension of such a profile curve is then calculated, and further studies are made on its fractal characteristics. As an exploration on tool types and individual identification, this is aimed to provide a new theory and approach to examination and identification of striation tool marks. 展开更多
关键词 fractal geometry fractal dimension striation tool marks profile curve
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Glaciation-induced features or sediment gravity flows——An analytic review
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作者 Mats O.Molen 《Journal of Palaeogeography》 SCIE CSCD 2023年第4期487-545,共59页
For more than 150 years, geologic characteristics claimed to be evidence for pre-Pleistocene glaciations have been debated. Advancements in recent decades, in understanding features generated by mainly glacial and mas... For more than 150 years, geologic characteristics claimed to be evidence for pre-Pleistocene glaciations have been debated. Advancements in recent decades, in understanding features generated by mainly glacial and mass flow processes, are here reviewed. Detailed studies of data offered in support of prePleistocene glaciations have led to revisions that involve environments of mass movements. Similarities and differences between Quaternary glaciogenic and mass movement features are examined, to provide a more systematic methodology for analysing the origins of more ancient deposits. Analyses and evaluation of data are from a) Quaternary glaciogenic sediments, b) formations which have been assigned to pre-Pleistocene glaciations, and c) formations with comparable features associated with mass movements(and occasionally tectonics). Multiple proxies are assembled to develop correct interpretations of ancient strata. The aim is not per se to reinterpret specific formations and past climate changes, but to enable data to be evaluated using a broader and more inclusive conceptual framework.Regularly occurring pre-Pleistocene features interpreted to be glaciogenic, have often been shown to have few or no Quaternary glaciogenic equivalents. These same features commonly form by sediment gravity flows or other non-glacial processes, which may have led to misinterpretations of ancient deposits. These features include, for example, environmental affinity of fossils, grading, bedding, fabrics, size and appearance of erratics, polished and striated clasts and surfaces(“pavements”), dropstones, and surface microtextures.Recent decades of progress in research relating to glacial and sediment gravity flow processes have resulted in proposals by geologists, based on more detailed field data, more often of an origin by mass movements and tectonism than glaciation.The most coherent data of this review, i.e., appearances of features produced by glaciation, sediment gravity flows and a few other geological processes, are summarized in a Diamict Origin Table. 展开更多
关键词 DIAMICTITE Tillite Sediment gravity flow(SGF) STRIATION Groove Dropstone Paleoclimate Fossil vegetation Glaciogenic proxies Surface microtexture Late Paleozoic ice age
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Methanol tolerance upgrading of Proteus mirabilis lipase by machine learning‑assisted directed evolution
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作者 Rui Ma Yingnan Li +1 位作者 Meng Zhang Fei Xu 《Systems Microbiology and Biomanufacturing》 EI 2023年第3期427-439,共13页
For many crucial industrial applications,enzyme-catalyzed processes take place in harsh organic solvent environments.However,it remains a challenging problem to improve enzyme stability in organic solvents.This study ... For many crucial industrial applications,enzyme-catalyzed processes take place in harsh organic solvent environments.However,it remains a challenging problem to improve enzyme stability in organic solvents.This study utilized the MLDE(machine learning-assisted directed evolution)protocol to improve the methanol tolerance of Proteus mirabilis lipase(PML).The machine learning(ML)models were trained based on 266 combinatorial mutants.Using top 3 in 22 regression models based on evaluation of tenfold cross-validation,the fitness landscape of the 8000 full-space combinatorial mutants was predicted.All mutants in the restricted library showed higher methanol tolerance,among which the methanol tolerance of G202N/K208G/G266S(NGS)was up to 13-fold compared with the wild-type.Molecular dynamics(MD)simulation showed that reconstructing of critical hydrogen bond network in the mutant region of NGS provides a more stable local structure.This compact structure may improve the methanol tolerance by preventing organic solvent molecules into the activity site and resisting structural destruction.This work provides a successful case of evolution guided by ML for higher organic solvent tolerance of enzyme,and may also be a reference for broad enzyme modifications. 展开更多
关键词 Organic solvent tolerance Enzyme engineering Fitness prediction Site striation mutagenesis Molecular dynamics
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Transverse striation needling for 30 cases of cervical spondylosis 被引量:2
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作者 张媛 马富强 +1 位作者 杨宗保 刘彩春 《World Journal of Acupuncture-Moxibustion》 CSCD 2017年第2期48-52,共5页
Objective To observe the clinical efficacy of transverse striation needling in treatment of cervical spondylosis.Method Thirty patients were diagnosed with cervical spondylosis in Guoyitang Clinic,Yanwu Branch of Zhon... Objective To observe the clinical efficacy of transverse striation needling in treatment of cervical spondylosis.Method Thirty patients were diagnosed with cervical spondylosis in Guoyitang Clinic,Yanwu Branch of Zhongshan Hospital,Xiamen University from July,2013 to March,2015,and were included into this study.Transverse striation needling,i.e.transverse insertion into the transverse striation of the cervical vertebra,was adopted for the 30 patients,and conventional acupuncture at Fēngchí(风池 GB 20,bilateral),Jiānj?ng(肩井 GB 21,bilateral) and Jiānzhōngshù(肩中俞 SI 15,bilateral) was combined.The treatment was conducted for once a day,twice a week,and 6 times were needed in total.Follow-up visit was performed two months after the treatment.Result Among the 30 patients,the markedly effective rate was 70.0%(21/30),effective rate was 30.0%(9/30),and the total effective rate was 100.0%.There was no relapse during two months after the treatment.Conclusion The therapeutic effect of transverse striation needling in treatment of cervical spondylosis was good. 展开更多
关键词 Cervical spondylosis transverse striation needling ACUPUNCTURE
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