This paper reports a new method of titration for very weak acids and bases using the appearance of incisions on oscillopolarogram to indicate the end-point.This method has the advantages of rapidity,simplicity,no indi...This paper reports a new method of titration for very weak acids and bases using the appearance of incisions on oscillopolarogram to indicate the end-point.This method has the advantages of rapidity,simplicity,no indicator needed as well as good precision.展开更多
Rapid analysis of metal ions and organic compounds in strong acidic solutions is of sustainable interest in multiple disciplines.However,complicated and time-consuming pretreatments are always required for MS analysis...Rapid analysis of metal ions and organic compounds in strong acidic solutions is of sustainable interest in multiple disciplines.However,complicated and time-consuming pretreatments are always required for MS analysis of the compounds in strong acidic solutions.Otherwise,it will result in a weak signal and cause serious damage to the mass spectrometer.Herein,a simple method inherited from nano-ESI MS was developed for rapid analysis of strong acidic solutions.Nanoliter(nL)strong acidic solution was first loaded in the nano-ESI emitter,followed by evaporation to remove the H+and leave the analytes on the wall of the nano-ESI emitter.The evaporation process can be completed within 1 min because of the extremely tiny volume(≤1 nL)of the loaded solution.Then,the dried analytes on the wall of the nano-ESI emitter were redissolved by loading a new solvent,followed by nano-ESI MS analysis.By using this method,metal ions and organic compounds in the strong acidic solution can be detected with low sample consumption(1 nL),high speed(<2 min/sample),high sensitivity(limit of detection=0.2µg/L),and high accuracy(>90%).Proof-of-concept applications of the present method have been successfully achieved for the analysis of gastric juice(pH of the sample=1),monitoring reaction catalyzed by strong acid(pH of the system=0),and micro-area analysis of ores(pH of the extraction solvent=0),showing great application potential in multiple fields.展开更多
目的:观察强酸性氧化电位水(EOW)对家兔实质层绿脓杆菌角膜溃疡动物模型的治疗作用。方法:实质层内注射接种法建立家兔绿脓杆菌角膜溃疡模型,随机分成实验组和对照组。采用EOW做为滴眼液,分别进行体外杀菌实验、动物实验、兔眼急性刺激...目的:观察强酸性氧化电位水(EOW)对家兔实质层绿脓杆菌角膜溃疡动物模型的治疗作用。方法:实质层内注射接种法建立家兔绿脓杆菌角膜溃疡模型,随机分成实验组和对照组。采用EOW做为滴眼液,分别进行体外杀菌实验、动物实验、兔眼急性刺激性实验,并进行感染角膜细菌培养计数及病理组织学观察。结果:EOW对无有机物保护的金黄色葡萄球菌、大肠杆菌、绿脓杆菌作用1分钟,均未见细菌生长;D ra ize评分结果表明,EOW无眼刺激性;动物实验表明,EOW治疗组与对照组相比治疗有效。结论:EOW原液治疗家兔绿脓杆菌角膜溃疡有效。因而,其有可能成为治疗绿脓杆菌角膜溃疡的一种方法。展开更多
文摘This paper reports a new method of titration for very weak acids and bases using the appearance of incisions on oscillopolarogram to indicate the end-point.This method has the advantages of rapidity,simplicity,no indicator needed as well as good precision.
基金supported by the National Natural Science Foundation of China(Nos.21864001,21727812 and 21765001)the Ph.D.Start-up Foundation of East China University of Technology(No.DHBK2020001).
文摘Rapid analysis of metal ions and organic compounds in strong acidic solutions is of sustainable interest in multiple disciplines.However,complicated and time-consuming pretreatments are always required for MS analysis of the compounds in strong acidic solutions.Otherwise,it will result in a weak signal and cause serious damage to the mass spectrometer.Herein,a simple method inherited from nano-ESI MS was developed for rapid analysis of strong acidic solutions.Nanoliter(nL)strong acidic solution was first loaded in the nano-ESI emitter,followed by evaporation to remove the H+and leave the analytes on the wall of the nano-ESI emitter.The evaporation process can be completed within 1 min because of the extremely tiny volume(≤1 nL)of the loaded solution.Then,the dried analytes on the wall of the nano-ESI emitter were redissolved by loading a new solvent,followed by nano-ESI MS analysis.By using this method,metal ions and organic compounds in the strong acidic solution can be detected with low sample consumption(1 nL),high speed(<2 min/sample),high sensitivity(limit of detection=0.2µg/L),and high accuracy(>90%).Proof-of-concept applications of the present method have been successfully achieved for the analysis of gastric juice(pH of the sample=1),monitoring reaction catalyzed by strong acid(pH of the system=0),and micro-area analysis of ores(pH of the extraction solvent=0),showing great application potential in multiple fields.
文摘目的:观察强酸性氧化电位水(EOW)对家兔实质层绿脓杆菌角膜溃疡动物模型的治疗作用。方法:实质层内注射接种法建立家兔绿脓杆菌角膜溃疡模型,随机分成实验组和对照组。采用EOW做为滴眼液,分别进行体外杀菌实验、动物实验、兔眼急性刺激性实验,并进行感染角膜细菌培养计数及病理组织学观察。结果:EOW对无有机物保护的金黄色葡萄球菌、大肠杆菌、绿脓杆菌作用1分钟,均未见细菌生长;D ra ize评分结果表明,EOW无眼刺激性;动物实验表明,EOW治疗组与对照组相比治疗有效。结论:EOW原液治疗家兔绿脓杆菌角膜溃疡有效。因而,其有可能成为治疗绿脓杆菌角膜溃疡的一种方法。
