In order to have knowledge about the college students'awareness and acceptance of genetically modified foods and their attitudes toward the identification of genetically modified foods and the government's reg...In order to have knowledge about the college students'awareness and acceptance of genetically modified foods and their attitudes toward the identification of genetically modified foods and the government's regulation,we conduct a questionnaire survey of 150 college students'cognition of genetically modified foods in North College Town of Zhengzhou City.The results show that the college students have a certain understanding of genetically modified foods,but the cognition level is low;electronic media has become the main channel for the current college students to know the information about genetically modified foods;for security reasons,the majority of college students are wary of genetically modified foods,and pay more attention to whether there is genetically modified component in the foods labeling;college students generally believe that the government should strengthen the supervision of genetically modified foods,and make the GM labeling system strict,to protect consumers'right to know and choice.展开更多
BACKGROUND Propofol and sevoflurane are commonly used anesthetic agents for maintenance anesthesia during radical resection of gastric cancer.However,there is a debate concerning their differential effects on cognitiv...BACKGROUND Propofol and sevoflurane are commonly used anesthetic agents for maintenance anesthesia during radical resection of gastric cancer.However,there is a debate concerning their differential effects on cognitive function,anxiety,and depression in patients undergoing this procedure.AIM To compare the effects of propofol and sevoflurane anesthesia on postoperative cognitive function,anxiety,depression,and organ function in patients undergoing radical resection of gastric cancer.METHODS A total of 80 patients were involved in this research.The subjects were divided into two groups:Propofol group and sevoflurane group.The evaluation scale for cognitive function was the Loewenstein occupational therapy cognitive assessment(LOTCA),and anxiety and depression were assessed with the aid of the self-rating anxiety scale(SAS)and self-rating depression scale(SDS).Hemodynamic indicators,oxidative stress levels,and pulmonary function were also measured.RESULTS The LOTCA score at 1 d after surgery was significantly lower in the propofol group than in the sevoflurane group.Additionally,the SAS and SDS scores of the sevoflurane group were significantly lower than those of the propofol group.The sevoflurane group showed greater stability in heart rate as well as the mean arterial pressure compared to the propofol group.Moreover,the sevoflurane group displayed better pulmonary function and less lung injury than the propofol group.CONCLUSION Both propofol and sevoflurane could be utilized as maintenance anesthesia during radical resection of gastric cancer.Propofol anesthesia has a minimal effect on patients'pulmonary function,consequently enhancing their postoperative recovery.Sevoflurane anesthesia causes less impairment on patients'cognitive function and mitigates negative emotions,leading to an improved postoperative mental state.Therefore,the selection of anesthetic agents should be based on the individual patient's specific circumstances.展开更多
Objective:To study the influence of cognition and emotion on moral judgment of college students under the circumstance of whether the cognitive resources are occupied and whether the emotion is induced.Methods:This ex...Objective:To study the influence of cognition and emotion on moral judgment of college students under the circumstance of whether the cognitive resources are occupied and whether the emotion is induced.Methods:This experiment uses a multi-factor mixed experiment method to divide experiments and groups.Experiment 1 uses a two-factor mixed experimental design of 2(cognitive resource occupancy group,cognitive resource non-occupied group)×3(difficult situation type).Experiment 2 uses a two-factor mixed experimental design of 2(emotion induction group,emotion induction and cognitive resource occupation group)×3(three types of dilemma situation types)is adopted.The dependent variable of this experiment(including Experiment 1 and Experiment 2)is the judgment response time and the judgment result is“Yes”(F)or“No”(J).Results:(1)The reaction time of the cognitive resource occupancy group was significantly higher than that of the cognitive resource non-occupied group,and the cognitive resource occupancy group in the three types of dilemma situations of high personal involvement,low personal involvement,and non-personal participation.There is no significant difference between the results of moral judgments and the cognitive resource non-occupied group.(2)In the three dilemmas of high personal involvement,low personal involvement,and non-personal participation,the emotion-induced group and the emotion-induced and cognitive resource occupation group have no significant differences in reaction time and moral judgment results.(3)In the three dilemmas of high personal involvement,low personal involvement,and non-personal participation,the reaction time difference between the cognitive resource occupation group and the emotionally induced and cognitive resource occupation is not significant,while in the dilemma of low personal involvement,the number of people in the cognitive resource occupation group whose moral judgment is“Yes”was significantly higher than that in the emotionally induced and cognitive resource occupation group.(4)In the three dilemmas of high personal involvement,low personal involvement,and non-personal participation,the reaction time of the emotionally induced group was significantly higher than that of the cognitive resource non-occupied group,and the moral judgment results of the two groups were both found no significant difference.Conclusion:When the occupation of cognitive resources and the induction of emotions will significantly affect the response of individual moral judgments,different types of dilemmas will significantly affect the results of individual moral judgments.展开更多
Background: Stroke survivors who exhibit impaired cognition at admission to inpatient rehabilitation may experience participation challenges and poorer functional outcomes than those without impaired cognition. Differ...Background: Stroke survivors who exhibit impaired cognition at admission to inpatient rehabilitation may experience participation challenges and poorer functional outcomes than those without impaired cognition. Differences in functional outcomes between stroke survivors with and without impaired cognition may be attributed to age, level of cognitive impairment, and severity of stroke. Materials and Methods: A retrospective secondary data analysis was conducted using health-related administrative data acquired from a Southwestern Ontario hospital’s stroke rehabilitation database. The aim was to explore potential linkages between post-stroke impaired cognition and functional gains, rehabilitation stays, and living settings after discharge from rehabilitation. Results: An aggregate sample of 393 males and 314 females subclassified as experiencing mild, moderate, and severe stroke was analyzed. At inpatient rehabilitation admission, 21.5% (n = 152) of these patients had no impaired cognition, 33.7% (n = 238) had mild impaired cognition, 22.2% (n = 157) had moderate impaired cognition, and 22.6% (n = 160) had severe impaired cognition. Cognitively impaired stroke patients were significantly (p 0.001) older, had (mostly) moderate to severe stroke with significantly (p = 0.012) more moderate cognitive impairment, had significantly (p 0.001) longer rehabilitation stays, and a high propensity for being discharged to longer-term care facilities compared to non-cognitively impaired patients. Conclusion: Presence of significant dissimilarity in rehabilitation stays and post-discharge destinations among stroke survivors with and without cognitive impairment is attributed to the age of the patient, level of cognitive impairment, and rigorous rehabilitation interventions.展开更多
Memory deficit,which is often associated with aging and many psychiatric,neurological,and neurodegenerative diseases,has been a challenging issue for treatment.Up till now,all potential drug candidates have failed to ...Memory deficit,which is often associated with aging and many psychiatric,neurological,and neurodegenerative diseases,has been a challenging issue for treatment.Up till now,all potential drug candidates have failed to produce satisfa ctory effects.Therefore,in the search for a solution,we found that a treatment with the gene corresponding to the RGS14414protein in visual area V2,a brain area connected with brain circuits of the ventral stream and the medial temporal lobe,which is crucial for object recognition memory(ORM),can induce enhancement of ORM.In this study,we demonstrated that the same treatment with RGS14414in visual area V2,which is relatively unaffected in neurodegenerative diseases such as Alzheimer s disease,produced longlasting enhancement of ORM in young animals and prevent ORM deficits in rodent models of aging and Alzheimer’s disease.Furthermore,we found that the prevention of memory deficits was mediated through the upregulation of neuronal arbo rization and spine density,as well as an increase in brain-derived neurotrophic factor(BDNF).A knockdown of BDNF gene in RGS14414-treated aging rats and Alzheimer s disease model mice caused complete loss in the upregulation of neuronal structural plasticity and in the prevention of ORM deficits.These findings suggest that BDNF-mediated neuronal structural plasticity in area V2 is crucial in the prevention of memory deficits in RGS14414-treated rodent models of aging and Alzheimer’s disease.Therefore,our findings of RGS14414gene-mediated activation of neuronal circuits in visual area V2 have therapeutic relevance in the treatment of memory deficits.展开更多
In recent years,the suicide rate of adolescents has been increasing year by year,and life and health problems have become the most important in education.It is urgent to promote the construction of the curriculum of l...In recent years,the suicide rate of adolescents has been increasing year by year,and life and health problems have become the most important in education.It is urgent to promote the construction of the curriculum of life education effectively.In view of the“vacuity”and“fragmented”state of traditional life education,this paper combs the teaching objectives,teaching contents,teaching methods,and teaching evaluation of life education from the perspective of embodied cognition theory,to explore the construction of positive experience of life education curriculum.展开更多
In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial cells.However,the functional role of GGT5 in the development of A...In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial cells.However,the functional role of GGT5 in the development of Alzheimer’s disease remains unclear.This study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying mechanism.We observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse model.Additionally,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive deficits.Interestingly,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 mice.This effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa B.Our findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 mice.These findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.展开更多
Edutainment,in the kindergarten education stage,emphasizes the game as the basic activity and combines the content of education with the form of the game,thus it also forms the educational method of gamification teach...Edutainment,in the kindergarten education stage,emphasizes the game as the basic activity and combines the content of education with the form of the game,thus it also forms the educational method of gamification teaching.Through investigation and analysis,it is found that the current kindergarten game activity design has the problem of improper combination of educational content and game form.The current kindergarten game activity design has problems such as stereotypes,children’s lack of active learning opportunities in activities,teachers’insufficient theoretical understanding,inappropriate teacher guidance methods,and so on.Embodied cognition theory attaches importance to the important role of the body in the development of cognition,provides new guidance for classroom teaching,and opens up a new path for classroom teaching reform.Based on the perspective of embodied cognition theory,the concept of body and mind integration should be adhered to in kindergarten teaching with games as the basic activity,experiential teaching situation should be created,children’s subjective experience should be respected,and games and interactions should be designed to promote children’s physical and mental participation,thus laying a foundation for the realization of children’s individual freedom,autonomy,and all-round development.Therefore,this paper aims at the existing problems in the current kindergarten gamification teaching and discusses the design strategy of children’s game activities based on embodied cognition theory.展开更多
Objective To study the relationship between contraceptive knowledge, cognition and behaviors among vocational high school students. Methods A cross-sectional survey was anonymously self-administrated by way of compute...Objective To study the relationship between contraceptive knowledge, cognition and behaviors among vocational high school students. Methods A cross-sectional survey was anonymously self-administrated by way of computer to all the 1st graders' among three vocational high schools in a district of Shanghai. Four cognition indicators, including perceived benefits, perceived barriers, perceived risks and self eJficacy were applied according to Health Belief Model. Results The percentage of respondents who reported ever sexual practices and contraceptives use at first sex was 7.01% and 56.64% respectively. Condom (58. 70%) and oral contraceptive pills (27.78%) were used by the majority. Main reasons for non-use were "shy to buy it" (26.53%) and "partner don't want to use any" (18.37%). Proportion of respondents who ever had sex regarded withdrawal and rhythm as effective were 68.35% and 68.42% respectively. Proportion of respondents having sex knew "If a person was infected with STDs, he/she might not have noticeable symptoms" were 22.86%. Proportion of respondents who reported non-use of contraceptives at first sex considered that "infrequent intercourse could not cause a girl pregnant even she had experienced her menstruation" were 40.63%. Proportion of respondents who had ever used condom got full score of knowledge on "how to correctly use condom" were 23,26%. Perceived risks were poorest among four cognition indicators. High level of contraceptive knowledge was connected with high rate of contraceptives use at first sex, whereas high level contraceptive cognition was connected with high rate of contraceptive use both at first and recent sex. Conclusions It is important to provide youth-friendly services as well as message on contraceptives among vocational school students.展开更多
基于剑桥大学出版社出版的认知语言学权威期刊Language and Cognition所刊发的10篇象似性论文,本文深度描写、分析并展望象似性研究的国际前沿现状,并对该辑专刊进行述评。结果发现,近年来国外象似性研究主要集中于象似性理论的跨学科...基于剑桥大学出版社出版的认知语言学权威期刊Language and Cognition所刊发的10篇象似性论文,本文深度描写、分析并展望象似性研究的国际前沿现状,并对该辑专刊进行述评。结果发现,近年来国外象似性研究主要集中于象似性理论的跨学科研究、手语语言学及其应用与实践等领域。上述发现不但有助于揭示语言与认知的关系,而且对于国内学者把握国际象似性研究的最新进展具有一定的参考意义。展开更多
Objective: To understand the status of cognition of palliative nursing among nursing students at different levels, and provide a basis for palliative nursing education. Methods: 268 nursing students from different lev...Objective: To understand the status of cognition of palliative nursing among nursing students at different levels, and provide a basis for palliative nursing education. Methods: 268 nursing students from different levels were investigated by the palliative nursing cognition questionnaire and Chinese version of palliative nursing knowledge questionnaire (PCQN). Results: Students with clinical probation and from non single parent family normally have higher knowledge scores than those without clinical probation and from single parent families (p Conclusion: It’s important for schools and hospitals to strengthen the theory teaching of palliative nursing, combine clinical practice with the theory education closely and improve the teaching level of teachers, which are aimed to promote the rapid development of palliative care.展开更多
Given the ongoing character of COVID-19, higher-education students encountered multifaceted pressures brought about by thepandemic and had to overcome many difficulties during this period. Accordingly, it is imperativ...Given the ongoing character of COVID-19, higher-education students encountered multifaceted pressures brought about by thepandemic and had to overcome many difficulties during this period. Accordingly, it is imperative to identify the factors that mayhave protective effects on the social functioning and mental status of college students in the aftermath of COVID-19. This crosssectional study sought to ascertain the internal mechanism of positive coping (PC) styles affecting post-traumatic growth (PTG)and considered the mediating roles of cognitive reappraisal (CR), psychological resilience (PR), and deliberate rumination (DR),which are essential for understanding how and to what extent these factors shaped PTG in the context of the present pandemic. 463Chinese college students recruited via a convenience sampling method completed a set of online self-report measures of PC, PTG,CR, PR and DR. The findings revealed that the abovementioned five variables were positively correlated with each other, and theindependent variable directly predicted the dependent variable. More importantly, two out of three mediators in parallel mediatedthe relationship between PC and PTG, illustrating that more PC adoption was associated with increased PTG through high levels ofPR and DR, respectively. The two significant serial mediating effects also indicated that PC could contribute to CR, which furtherfacilitates either PR or DR and subsequently promotes the development of PTG. Colleges should adopt routine protectivebehaviors in accordance with such evidence to strengthen students’ mental health education and establish scientific methods toboost their psychological well-being. Overall, our results may shed new light on the process of positive adaption and providetheoretical support for targeted crisis intervention during the late phase of the pandemic.展开更多
Questionnaire survey and investigation were carried out to get students’feelings and cognition about campus of Peking University Shenzhen Graduate School,and active paths of their daily routine were analyzed to fi gu...Questionnaire survey and investigation were carried out to get students’feelings and cognition about campus of Peking University Shenzhen Graduate School,and active paths of their daily routine were analyzed to fi gure out the relationship between cognition and path.Characteristics of the students’space cognition and time-space active path were analyzed,and the causes of these characteristics explored to summarize the laws of students’daily life,and provide references to know psychologic status of students.展开更多
Under the influence of European rationalism,which holds that human rationality is higher than,or at least independent of human sensory cognition,the first generation of cognitive science advocates for disembodied cogn...Under the influence of European rationalism,which holds that human rationality is higher than,or at least independent of human sensory cognition,the first generation of cognitive science advocates for disembodied cognition,manifesting the concept of dualism of mind and body.With the development of cognitive science in the 1980s,the second generation of cognitive science redefines the relationship between mind and body,thought and behavior,and reason and feeling and puts forward the concept of embodied cognition,representing monism of mind and body.It is claimed that the formation of concepts,categorical cognition and the evolution of rational thinking are characterized by embodiment,which is the necessary condition and basis for the formation of human rationality.The current study traces the shift of cognitive science from dualism to monism of mind and body and explores the relationship between rationality and sensibility from the perspective of philosophical basis and interpretations,with an aim to achieve a better understanding and thorough interpretation of human rationality.In this heated discussion about embodied cognition,there are still some fundamental questions that need to be further clarified,such as the essence and mechanism of human cognition,the ways that human body participates in cognitive activities,especially imagination and reasoning.The research paradigm of embodied cognition and its relevant theory have not been established and developed yet,and empirical research from interdisciplinary perspectives is far from enough to provide hard evidence for embodied cognition.展开更多
This article delves into the intricate relationship between cognitive science and embodied cognition, offering transformative philosophical insights with profound implications for our understanding of the mind-body co...This article delves into the intricate relationship between cognitive science and embodied cognition, offering transformative philosophical insights with profound implications for our understanding of the mind-body connection. In response to the journal’s feedback, we have enhanced the abstract to provide a more comprehensive overview of our study. Background: We trace the historical evolution of ideas, from the inception of cognitive science rooted in analytic philosophy to the groundbreaking contributions of Rodney Brooks and others in the field of artificial intelligence. We also explore the work of scholars such as Agre, Chapman, and Dreyfus, shedding light on the role of cognitive metaphor and the concept of the cognitive unconscious in shaping our understanding of embodied cognition. Purpose: Our study aims to shed light on the central theme that unites these various strands of thought—the rejection of the traditional, transcendental view of the subject in favor of the concept of an embodied subject. This embodied subject actively engages with its environment, shaping consciousness and cognition. This shift in perspective challenges classical epistemological theories and opens new avenues for inquiry. Method: We have conducted a comprehensive literature review to explore the historical development and key concepts in the field of embodied cognition, with a particular focus on the philosophical underpinnings and their integration into cognitive science. Results: Our examination of embodied cognition reveals that the mind is intimately connected to the body, with cognition emerging through interactions with the environment and perceptual experiences. This perspective challenges reductionist notions and demonstrates that mental states cannot be reduced to brain states alone. We also explore the relationship between functionalism and computational states of the brain, illustrating that mental states can be understood in the context of mathematical functions. Conclusion: In conclusion, this paper highlights the profound implications of embodied cognition and suggests that the mind is not isolated from the body but intimately tied to it. This perspective provides a fresh approach to the mind-body problem, emphasizing the role of the environment and perceptual experiences in shaping cognition. We invite further research into the practical applications of embodied cognition in fields like artificial intelligence, robotics, and psychology, and encourage investigations into the intersections between cognitive science and various branches of philosophy, offering valuable insights into the nature of consciousness and cognition. In essence, this study provides a comprehensive overview of the evolution and implications of embodied cognition, laying the groundwork for further research and fostering a deeper appreciation of the profound shifts in perspective that this theory brings to our understanding of the human mind.展开更多
Intellectualization has been an inevitable trend in the information network,allowing the network to achieve the capabilities of self-learning,self-optimization,and self-evolution in the dynamic environment.Due to the ...Intellectualization has been an inevitable trend in the information network,allowing the network to achieve the capabilities of self-learning,self-optimization,and self-evolution in the dynamic environment.Due to the strong adaptability to the environment,the cognitive theory methods from psychology gradually become an excellent approach to construct the intelligent information network(IIN),making the traditional definition of the intelligent information network no longer appropriate.Moreover,the thinking capability of existing IINs is always limited.This paper redefines the intelligent information network and illustrates the required properties of the architecture,core theory,and critical technologies by analyzing the existing intelligent information network.Besides,we innovatively propose a novel network cognition model with the network knowledge to implement the intelligent information network.The proposed model can perceive the overall environment data of the network and extract the knowledge from the data.As the model’s core,the knowledge guides the model to generate the optimal decisions adapting to the environmental changes.At last,we present the critical technologies needed to accomplish the proposed network cognition model.展开更多
Dementia prevalence has soared due to population aging. In Mild Cognitive Impairment (MCI) as a pre-dementia stage, sleepdisturbances have raised much interest as a factor in a bidirectional relationship with cognitiv...Dementia prevalence has soared due to population aging. In Mild Cognitive Impairment (MCI) as a pre-dementia stage, sleepdisturbances have raised much interest as a factor in a bidirectional relationship with cognitive decline. Thus, this studydeveloped the Sleep and Cognition Enhancement Multimodal Intervention (SCEMI) based on Lazarus’ multimodal approachand conducted a randomized controlled experiment to investigate the effects of the novel program on sleep and cognition inMCI elderly. The participants were 55 MCI elderly with sleep disturbances at two dementia care centers located in S-city,Gyeonggi-do, South Korea (n = 25 in the experimental group and n = 30 in the control group). The study period was fromNovember 01 to December 27, 2022. The experimental group received 8 sessions of SCEMI, 60 min per session once a week.The control group received general education and guidance using a simplified booklet on the sleep and cognitive improvement.For data collection, a self-reported questionnaire was used to investigate sleep quality, presleep arousal, cognitive function,stress, and depression. The results showed that, compared to the control group, the experimental group had significantlyimproved across all variables: sleep quality (U = 109.50, p < 0.001), presleep arousal (U = 11.50, p < 0.001), cognitive function(U = 72.00, p < 0.001), stress (U = 139.00, p < 0.001), and depression (U = 231.50, p = 0.015). Thus, the SCEMI appears topositively affect symptomatic improvement and delays the progression to dementia as an integrated intervention to enhancesleep and cognition in community-dwelling MCI elderly with sleep disturbances.展开更多
Introduction: Sleep is critical to human physiological function, cognitive performance, and emotional regulation. Healthcare personnel, especially physicians, are chronically exposed to long working hours, which are o...Introduction: Sleep is critical to human physiological function, cognitive performance, and emotional regulation. Healthcare personnel, especially physicians, are chronically exposed to long working hours, which are often accompanied by decreased sleep time. Clinical evidence indicates that these conditions affect their cognitive function and professional practice, but researchers in the field have not sufficiently explored the possible effects of reductions in sleep time on social cognition. Objective: The aim of this is to further explore the effects of sleep restriction among medical residents, the specific impairments in social cognition that it produces, and the effects of a sleep hygiene orientation on those impairments. Method: There were 124 medical residents (50 males, 74 females) who completed a daily sleep/work log, a battery of sleep tests/questionnaires, and neuropsychological evaluations. The participants then received a short course (8 hours) on basic concepts of sleep hygiene and sleep psychoeducation. Once the course was completed, participants filled out the questionnaires again. Results: The results indicate that sleep disturbances in medical residents were associated with severe neurocognitive and social cognition impairments. After the sleep hygiene intervention, neuropsychological function and sleep parameters improved, awareness increased, and social cognition performance significantly improved. Conclusion: Using sleep psychoeducation and sleep hygiene intervention in medical residents is a simple strategy to mitigate the effects of sleep restriction.展开更多
Objective:To investigate medical students’cognition on the doctor-patient relationship and its influence on their career choice as well as to provide reference for medical education and communication education.Method...Objective:To investigate medical students’cognition on the doctor-patient relationship and its influence on their career choice as well as to provide reference for medical education and communication education.Methods:A self-compiled questionnaire survey was carried out at a medical university in W city,and descriptive statistics as well as chi-square tests were conducted.Results:There were significant differences in medical students’cognition of doctor-patient relationship among different genders,registered residence,only-child status,whose parents are working in the medical field,and their own evaluation of the major(p<0.05);the different cognitions of doctor-patient relationship have a significant influence on medical students’career choice.Conclusion:Medical students’vocational cognition and educational guidance should be strengthened,hospital information should be open and transparent,media reporting of medical events should be standardized,and a doctor-patient conflict regulation mechanism should be established.展开更多
基金Supported by Henan Provincial Government's Decision-making Research and Bid Invitation Project(2012B763)
文摘In order to have knowledge about the college students'awareness and acceptance of genetically modified foods and their attitudes toward the identification of genetically modified foods and the government's regulation,we conduct a questionnaire survey of 150 college students'cognition of genetically modified foods in North College Town of Zhengzhou City.The results show that the college students have a certain understanding of genetically modified foods,but the cognition level is low;electronic media has become the main channel for the current college students to know the information about genetically modified foods;for security reasons,the majority of college students are wary of genetically modified foods,and pay more attention to whether there is genetically modified component in the foods labeling;college students generally believe that the government should strengthen the supervision of genetically modified foods,and make the GM labeling system strict,to protect consumers'right to know and choice.
文摘BACKGROUND Propofol and sevoflurane are commonly used anesthetic agents for maintenance anesthesia during radical resection of gastric cancer.However,there is a debate concerning their differential effects on cognitive function,anxiety,and depression in patients undergoing this procedure.AIM To compare the effects of propofol and sevoflurane anesthesia on postoperative cognitive function,anxiety,depression,and organ function in patients undergoing radical resection of gastric cancer.METHODS A total of 80 patients were involved in this research.The subjects were divided into two groups:Propofol group and sevoflurane group.The evaluation scale for cognitive function was the Loewenstein occupational therapy cognitive assessment(LOTCA),and anxiety and depression were assessed with the aid of the self-rating anxiety scale(SAS)and self-rating depression scale(SDS).Hemodynamic indicators,oxidative stress levels,and pulmonary function were also measured.RESULTS The LOTCA score at 1 d after surgery was significantly lower in the propofol group than in the sevoflurane group.Additionally,the SAS and SDS scores of the sevoflurane group were significantly lower than those of the propofol group.The sevoflurane group showed greater stability in heart rate as well as the mean arterial pressure compared to the propofol group.Moreover,the sevoflurane group displayed better pulmonary function and less lung injury than the propofol group.CONCLUSION Both propofol and sevoflurane could be utilized as maintenance anesthesia during radical resection of gastric cancer.Propofol anesthesia has a minimal effect on patients'pulmonary function,consequently enhancing their postoperative recovery.Sevoflurane anesthesia causes less impairment on patients'cognitive function and mitigates negative emotions,leading to an improved postoperative mental state.Therefore,the selection of anesthetic agents should be based on the individual patient's specific circumstances.
基金This work was supported by Natural Science Foundation of Hainan Province:Research on the Cognitive and Emotional Processing Mechanism of Moral Judgment(Project No.719MS056).
文摘Objective:To study the influence of cognition and emotion on moral judgment of college students under the circumstance of whether the cognitive resources are occupied and whether the emotion is induced.Methods:This experiment uses a multi-factor mixed experiment method to divide experiments and groups.Experiment 1 uses a two-factor mixed experimental design of 2(cognitive resource occupancy group,cognitive resource non-occupied group)×3(difficult situation type).Experiment 2 uses a two-factor mixed experimental design of 2(emotion induction group,emotion induction and cognitive resource occupation group)×3(three types of dilemma situation types)is adopted.The dependent variable of this experiment(including Experiment 1 and Experiment 2)is the judgment response time and the judgment result is“Yes”(F)or“No”(J).Results:(1)The reaction time of the cognitive resource occupancy group was significantly higher than that of the cognitive resource non-occupied group,and the cognitive resource occupancy group in the three types of dilemma situations of high personal involvement,low personal involvement,and non-personal participation.There is no significant difference between the results of moral judgments and the cognitive resource non-occupied group.(2)In the three dilemmas of high personal involvement,low personal involvement,and non-personal participation,the emotion-induced group and the emotion-induced and cognitive resource occupation group have no significant differences in reaction time and moral judgment results.(3)In the three dilemmas of high personal involvement,low personal involvement,and non-personal participation,the reaction time difference between the cognitive resource occupation group and the emotionally induced and cognitive resource occupation is not significant,while in the dilemma of low personal involvement,the number of people in the cognitive resource occupation group whose moral judgment is“Yes”was significantly higher than that in the emotionally induced and cognitive resource occupation group.(4)In the three dilemmas of high personal involvement,low personal involvement,and non-personal participation,the reaction time of the emotionally induced group was significantly higher than that of the cognitive resource non-occupied group,and the moral judgment results of the two groups were both found no significant difference.Conclusion:When the occupation of cognitive resources and the induction of emotions will significantly affect the response of individual moral judgments,different types of dilemmas will significantly affect the results of individual moral judgments.
文摘Background: Stroke survivors who exhibit impaired cognition at admission to inpatient rehabilitation may experience participation challenges and poorer functional outcomes than those without impaired cognition. Differences in functional outcomes between stroke survivors with and without impaired cognition may be attributed to age, level of cognitive impairment, and severity of stroke. Materials and Methods: A retrospective secondary data analysis was conducted using health-related administrative data acquired from a Southwestern Ontario hospital’s stroke rehabilitation database. The aim was to explore potential linkages between post-stroke impaired cognition and functional gains, rehabilitation stays, and living settings after discharge from rehabilitation. Results: An aggregate sample of 393 males and 314 females subclassified as experiencing mild, moderate, and severe stroke was analyzed. At inpatient rehabilitation admission, 21.5% (n = 152) of these patients had no impaired cognition, 33.7% (n = 238) had mild impaired cognition, 22.2% (n = 157) had moderate impaired cognition, and 22.6% (n = 160) had severe impaired cognition. Cognitively impaired stroke patients were significantly (p 0.001) older, had (mostly) moderate to severe stroke with significantly (p = 0.012) more moderate cognitive impairment, had significantly (p 0.001) longer rehabilitation stays, and a high propensity for being discharged to longer-term care facilities compared to non-cognitively impaired patients. Conclusion: Presence of significant dissimilarity in rehabilitation stays and post-discharge destinations among stroke survivors with and without cognitive impairment is attributed to the age of the patient, level of cognitive impairment, and rigorous rehabilitation interventions.
基金supported by grants from the Ministerio de Economia y Competitividad(BFU2013-43458-R)Junta de Andalucia(P12-CTS-1694 and Proyexcel-00422)to ZUK。
文摘Memory deficit,which is often associated with aging and many psychiatric,neurological,and neurodegenerative diseases,has been a challenging issue for treatment.Up till now,all potential drug candidates have failed to produce satisfa ctory effects.Therefore,in the search for a solution,we found that a treatment with the gene corresponding to the RGS14414protein in visual area V2,a brain area connected with brain circuits of the ventral stream and the medial temporal lobe,which is crucial for object recognition memory(ORM),can induce enhancement of ORM.In this study,we demonstrated that the same treatment with RGS14414in visual area V2,which is relatively unaffected in neurodegenerative diseases such as Alzheimer s disease,produced longlasting enhancement of ORM in young animals and prevent ORM deficits in rodent models of aging and Alzheimer’s disease.Furthermore,we found that the prevention of memory deficits was mediated through the upregulation of neuronal arbo rization and spine density,as well as an increase in brain-derived neurotrophic factor(BDNF).A knockdown of BDNF gene in RGS14414-treated aging rats and Alzheimer s disease model mice caused complete loss in the upregulation of neuronal structural plasticity and in the prevention of ORM deficits.These findings suggest that BDNF-mediated neuronal structural plasticity in area V2 is crucial in the prevention of memory deficits in RGS14414-treated rodent models of aging and Alzheimer’s disease.Therefore,our findings of RGS14414gene-mediated activation of neuronal circuits in visual area V2 have therapeutic relevance in the treatment of memory deficits.
基金Project of Wenzhou Philosophy and Social Sciences Planning“Research on the Necessity and Breakthrough Path of the Integration of Life Education”(Project number:23WSK024YB)。
文摘In recent years,the suicide rate of adolescents has been increasing year by year,and life and health problems have become the most important in education.It is urgent to promote the construction of the curriculum of life education effectively.In view of the“vacuity”and“fragmented”state of traditional life education,this paper combs the teaching objectives,teaching contents,teaching methods,and teaching evaluation of life education from the perspective of embodied cognition theory,to explore the construction of positive experience of life education curriculum.
基金supported by STI2030-Major Projects,No.2021ZD 0201801(to JG)Shanxi Province Basic Research Program,No.20210302123429(to QS).
文摘In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial cells.However,the functional role of GGT5 in the development of Alzheimer’s disease remains unclear.This study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying mechanism.We observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse model.Additionally,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive deficits.Interestingly,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 mice.This effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa B.Our findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 mice.These findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.
文摘Edutainment,in the kindergarten education stage,emphasizes the game as the basic activity and combines the content of education with the form of the game,thus it also forms the educational method of gamification teaching.Through investigation and analysis,it is found that the current kindergarten game activity design has the problem of improper combination of educational content and game form.The current kindergarten game activity design has problems such as stereotypes,children’s lack of active learning opportunities in activities,teachers’insufficient theoretical understanding,inappropriate teacher guidance methods,and so on.Embodied cognition theory attaches importance to the important role of the body in the development of cognition,provides new guidance for classroom teaching,and opens up a new path for classroom teaching reform.Based on the perspective of embodied cognition theory,the concept of body and mind integration should be adhered to in kindergarten teaching with games as the basic activity,experiential teaching situation should be created,children’s subjective experience should be respected,and games and interactions should be designed to promote children’s physical and mental participation,thus laying a foundation for the realization of children’s individual freedom,autonomy,and all-round development.Therefore,this paper aims at the existing problems in the current kindergarten gamification teaching and discusses the design strategy of children’s game activities based on embodied cognition theory.
文摘Objective To study the relationship between contraceptive knowledge, cognition and behaviors among vocational high school students. Methods A cross-sectional survey was anonymously self-administrated by way of computer to all the 1st graders' among three vocational high schools in a district of Shanghai. Four cognition indicators, including perceived benefits, perceived barriers, perceived risks and self eJficacy were applied according to Health Belief Model. Results The percentage of respondents who reported ever sexual practices and contraceptives use at first sex was 7.01% and 56.64% respectively. Condom (58. 70%) and oral contraceptive pills (27.78%) were used by the majority. Main reasons for non-use were "shy to buy it" (26.53%) and "partner don't want to use any" (18.37%). Proportion of respondents who ever had sex regarded withdrawal and rhythm as effective were 68.35% and 68.42% respectively. Proportion of respondents having sex knew "If a person was infected with STDs, he/she might not have noticeable symptoms" were 22.86%. Proportion of respondents who reported non-use of contraceptives at first sex considered that "infrequent intercourse could not cause a girl pregnant even she had experienced her menstruation" were 40.63%. Proportion of respondents who had ever used condom got full score of knowledge on "how to correctly use condom" were 23,26%. Perceived risks were poorest among four cognition indicators. High level of contraceptive knowledge was connected with high rate of contraceptives use at first sex, whereas high level contraceptive cognition was connected with high rate of contraceptive use both at first and recent sex. Conclusions It is important to provide youth-friendly services as well as message on contraceptives among vocational school students.
文摘基于剑桥大学出版社出版的认知语言学权威期刊Language and Cognition所刊发的10篇象似性论文,本文深度描写、分析并展望象似性研究的国际前沿现状,并对该辑专刊进行述评。结果发现,近年来国外象似性研究主要集中于象似性理论的跨学科研究、手语语言学及其应用与实践等领域。上述发现不但有助于揭示语言与认知的关系,而且对于国内学者把握国际象似性研究的最新进展具有一定的参考意义。
文摘Objective: To understand the status of cognition of palliative nursing among nursing students at different levels, and provide a basis for palliative nursing education. Methods: 268 nursing students from different levels were investigated by the palliative nursing cognition questionnaire and Chinese version of palliative nursing knowledge questionnaire (PCQN). Results: Students with clinical probation and from non single parent family normally have higher knowledge scores than those without clinical probation and from single parent families (p Conclusion: It’s important for schools and hospitals to strengthen the theory teaching of palliative nursing, combine clinical practice with the theory education closely and improve the teaching level of teachers, which are aimed to promote the rapid development of palliative care.
基金funded by The National Social Science Fund of China,Grant Number:BIA200182(Jinsheng Hu).
文摘Given the ongoing character of COVID-19, higher-education students encountered multifaceted pressures brought about by thepandemic and had to overcome many difficulties during this period. Accordingly, it is imperative to identify the factors that mayhave protective effects on the social functioning and mental status of college students in the aftermath of COVID-19. This crosssectional study sought to ascertain the internal mechanism of positive coping (PC) styles affecting post-traumatic growth (PTG)and considered the mediating roles of cognitive reappraisal (CR), psychological resilience (PR), and deliberate rumination (DR),which are essential for understanding how and to what extent these factors shaped PTG in the context of the present pandemic. 463Chinese college students recruited via a convenience sampling method completed a set of online self-report measures of PC, PTG,CR, PR and DR. The findings revealed that the abovementioned five variables were positively correlated with each other, and theindependent variable directly predicted the dependent variable. More importantly, two out of three mediators in parallel mediatedthe relationship between PC and PTG, illustrating that more PC adoption was associated with increased PTG through high levels ofPR and DR, respectively. The two significant serial mediating effects also indicated that PC could contribute to CR, which furtherfacilitates either PR or DR and subsequently promotes the development of PTG. Colleges should adopt routine protectivebehaviors in accordance with such evidence to strengthen students’ mental health education and establish scientific methods toboost their psychological well-being. Overall, our results may shed new light on the process of positive adaption and providetheoretical support for targeted crisis intervention during the late phase of the pandemic.
文摘Questionnaire survey and investigation were carried out to get students’feelings and cognition about campus of Peking University Shenzhen Graduate School,and active paths of their daily routine were analyzed to fi gure out the relationship between cognition and path.Characteristics of the students’space cognition and time-space active path were analyzed,and the causes of these characteristics explored to summarize the laws of students’daily life,and provide references to know psychologic status of students.
文摘Under the influence of European rationalism,which holds that human rationality is higher than,or at least independent of human sensory cognition,the first generation of cognitive science advocates for disembodied cognition,manifesting the concept of dualism of mind and body.With the development of cognitive science in the 1980s,the second generation of cognitive science redefines the relationship between mind and body,thought and behavior,and reason and feeling and puts forward the concept of embodied cognition,representing monism of mind and body.It is claimed that the formation of concepts,categorical cognition and the evolution of rational thinking are characterized by embodiment,which is the necessary condition and basis for the formation of human rationality.The current study traces the shift of cognitive science from dualism to monism of mind and body and explores the relationship between rationality and sensibility from the perspective of philosophical basis and interpretations,with an aim to achieve a better understanding and thorough interpretation of human rationality.In this heated discussion about embodied cognition,there are still some fundamental questions that need to be further clarified,such as the essence and mechanism of human cognition,the ways that human body participates in cognitive activities,especially imagination and reasoning.The research paradigm of embodied cognition and its relevant theory have not been established and developed yet,and empirical research from interdisciplinary perspectives is far from enough to provide hard evidence for embodied cognition.
文摘This article delves into the intricate relationship between cognitive science and embodied cognition, offering transformative philosophical insights with profound implications for our understanding of the mind-body connection. In response to the journal’s feedback, we have enhanced the abstract to provide a more comprehensive overview of our study. Background: We trace the historical evolution of ideas, from the inception of cognitive science rooted in analytic philosophy to the groundbreaking contributions of Rodney Brooks and others in the field of artificial intelligence. We also explore the work of scholars such as Agre, Chapman, and Dreyfus, shedding light on the role of cognitive metaphor and the concept of the cognitive unconscious in shaping our understanding of embodied cognition. Purpose: Our study aims to shed light on the central theme that unites these various strands of thought—the rejection of the traditional, transcendental view of the subject in favor of the concept of an embodied subject. This embodied subject actively engages with its environment, shaping consciousness and cognition. This shift in perspective challenges classical epistemological theories and opens new avenues for inquiry. Method: We have conducted a comprehensive literature review to explore the historical development and key concepts in the field of embodied cognition, with a particular focus on the philosophical underpinnings and their integration into cognitive science. Results: Our examination of embodied cognition reveals that the mind is intimately connected to the body, with cognition emerging through interactions with the environment and perceptual experiences. This perspective challenges reductionist notions and demonstrates that mental states cannot be reduced to brain states alone. We also explore the relationship between functionalism and computational states of the brain, illustrating that mental states can be understood in the context of mathematical functions. Conclusion: In conclusion, this paper highlights the profound implications of embodied cognition and suggests that the mind is not isolated from the body but intimately tied to it. This perspective provides a fresh approach to the mind-body problem, emphasizing the role of the environment and perceptual experiences in shaping cognition. We invite further research into the practical applications of embodied cognition in fields like artificial intelligence, robotics, and psychology, and encourage investigations into the intersections between cognitive science and various branches of philosophy, offering valuable insights into the nature of consciousness and cognition. In essence, this study provides a comprehensive overview of the evolution and implications of embodied cognition, laying the groundwork for further research and fostering a deeper appreciation of the profound shifts in perspective that this theory brings to our understanding of the human mind.
基金supported by the China Postdoctoral Science Foundation (Grant No.2020M673687)。
文摘Intellectualization has been an inevitable trend in the information network,allowing the network to achieve the capabilities of self-learning,self-optimization,and self-evolution in the dynamic environment.Due to the strong adaptability to the environment,the cognitive theory methods from psychology gradually become an excellent approach to construct the intelligent information network(IIN),making the traditional definition of the intelligent information network no longer appropriate.Moreover,the thinking capability of existing IINs is always limited.This paper redefines the intelligent information network and illustrates the required properties of the architecture,core theory,and critical technologies by analyzing the existing intelligent information network.Besides,we innovatively propose a novel network cognition model with the network knowledge to implement the intelligent information network.The proposed model can perceive the overall environment data of the network and extract the knowledge from the data.As the model’s core,the knowledge guides the model to generate the optimal decisions adapting to the environmental changes.At last,we present the critical technologies needed to accomplish the proposed network cognition model.
文摘Dementia prevalence has soared due to population aging. In Mild Cognitive Impairment (MCI) as a pre-dementia stage, sleepdisturbances have raised much interest as a factor in a bidirectional relationship with cognitive decline. Thus, this studydeveloped the Sleep and Cognition Enhancement Multimodal Intervention (SCEMI) based on Lazarus’ multimodal approachand conducted a randomized controlled experiment to investigate the effects of the novel program on sleep and cognition inMCI elderly. The participants were 55 MCI elderly with sleep disturbances at two dementia care centers located in S-city,Gyeonggi-do, South Korea (n = 25 in the experimental group and n = 30 in the control group). The study period was fromNovember 01 to December 27, 2022. The experimental group received 8 sessions of SCEMI, 60 min per session once a week.The control group received general education and guidance using a simplified booklet on the sleep and cognitive improvement.For data collection, a self-reported questionnaire was used to investigate sleep quality, presleep arousal, cognitive function,stress, and depression. The results showed that, compared to the control group, the experimental group had significantlyimproved across all variables: sleep quality (U = 109.50, p < 0.001), presleep arousal (U = 11.50, p < 0.001), cognitive function(U = 72.00, p < 0.001), stress (U = 139.00, p < 0.001), and depression (U = 231.50, p = 0.015). Thus, the SCEMI appears topositively affect symptomatic improvement and delays the progression to dementia as an integrated intervention to enhancesleep and cognition in community-dwelling MCI elderly with sleep disturbances.
文摘Introduction: Sleep is critical to human physiological function, cognitive performance, and emotional regulation. Healthcare personnel, especially physicians, are chronically exposed to long working hours, which are often accompanied by decreased sleep time. Clinical evidence indicates that these conditions affect their cognitive function and professional practice, but researchers in the field have not sufficiently explored the possible effects of reductions in sleep time on social cognition. Objective: The aim of this is to further explore the effects of sleep restriction among medical residents, the specific impairments in social cognition that it produces, and the effects of a sleep hygiene orientation on those impairments. Method: There were 124 medical residents (50 males, 74 females) who completed a daily sleep/work log, a battery of sleep tests/questionnaires, and neuropsychological evaluations. The participants then received a short course (8 hours) on basic concepts of sleep hygiene and sleep psychoeducation. Once the course was completed, participants filled out the questionnaires again. Results: The results indicate that sleep disturbances in medical residents were associated with severe neurocognitive and social cognition impairments. After the sleep hygiene intervention, neuropsychological function and sleep parameters improved, awareness increased, and social cognition performance significantly improved. Conclusion: Using sleep psychoeducation and sleep hygiene intervention in medical residents is a simple strategy to mitigate the effects of sleep restriction.
文摘Objective:To investigate medical students’cognition on the doctor-patient relationship and its influence on their career choice as well as to provide reference for medical education and communication education.Methods:A self-compiled questionnaire survey was carried out at a medical university in W city,and descriptive statistics as well as chi-square tests were conducted.Results:There were significant differences in medical students’cognition of doctor-patient relationship among different genders,registered residence,only-child status,whose parents are working in the medical field,and their own evaluation of the major(p<0.05);the different cognitions of doctor-patient relationship have a significant influence on medical students’career choice.Conclusion:Medical students’vocational cognition and educational guidance should be strengthened,hospital information should be open and transparent,media reporting of medical events should be standardized,and a doctor-patient conflict regulation mechanism should be established.