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Scenario Modeling-Aided AP Placement Optimization Method for Indoor Localization and Network Access
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作者 Pan Hao Chen Yu +1 位作者 Qi Xiaogang Liu Meili 《China Communications》 SCIE CSCD 2024年第3期37-50,共14页
Owing to the ubiquity of wireless networks and the popularity of WiFi infrastructures,received signal strength(RSS)-based indoor localization systems have received much attention.The placement of access points(APs)sig... Owing to the ubiquity of wireless networks and the popularity of WiFi infrastructures,received signal strength(RSS)-based indoor localization systems have received much attention.The placement of access points(APs)significantly influences localization accuracy and network access.However,the indoor scenario and network access are not fully considered in previous AP placement optimization methods.This study proposes a practical scenario modelingaided AP placement optimization method for improving localization accuracy and network access.In order to reduce the gap between simulation-based and field measurement-based AP placement optimization methods,we introduce an indoor scenario modeling and Gaussian process-based RSS prediction method.After that,the localization and network access metrics are implemented in the multiple objective particle swarm optimization(MOPSO)solution,Pareto front criterion and virtual repulsion force are applied to determine the optimal AP placement.Finally,field experiments demonstrate the effectiveness of the proposed indoor scenario modeling method and RSS prediction model.A thorough comparison confirms the localization and network access improvement attributed to the proposed anchor placement method. 展开更多
关键词 indoor localization MOPSO network access RSS prediction
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A HEVC Video Steganalysis Method Using the Optimality of Motion Vector Prediction
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作者 Jun Li Minqing Zhang +2 位作者 Ke Niu Yingnan Zhang Xiaoyuan Yang 《Computers, Materials & Continua》 SCIE EI 2024年第5期2085-2103,共19页
Among steganalysis techniques,detection against MV(motion vector)domain-based video steganography in the HEVC(High Efficiency Video Coding)standard remains a challenging issue.For the purpose of improving the detectio... Among steganalysis techniques,detection against MV(motion vector)domain-based video steganography in the HEVC(High Efficiency Video Coding)standard remains a challenging issue.For the purpose of improving the detection performance,this paper proposes a steganalysis method that can perfectly detectMV-based steganography in HEVC.Firstly,we define the local optimality of MVP(Motion Vector Prediction)based on the technology of AMVP(Advanced Motion Vector Prediction).Secondly,we analyze that in HEVC video,message embedding either usingMVP index orMVD(Motion Vector Difference)may destroy the above optimality of MVP.And then,we define the optimal rate of MVP as a steganalysis feature.Finally,we conduct steganalysis detection experiments on two general datasets for three popular steganographymethods and compare the performance with four state-ofthe-art steganalysis methods.The experimental results demonstrate the effectiveness of the proposed feature set.Furthermore,our method stands out for its practical applicability,requiring no model training and exhibiting low computational complexity,making it a viable solution for real-world scenarios. 展开更多
关键词 Video steganography video steganalysis motion vector prediction motion vector difference advanced motion vector prediction local optimality
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Application of the Conditional Nonlinear Local Lyapunov Exponent to Second-Kind Predictability
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作者 Ming ZHANG Ruiqiang DING +2 位作者 Quanjia ZHONG Jianping LI Deyu LU 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第9期1769-1786,共18页
In order to quantify the influence of external forcings on the predictability limit using observational data,the author introduced an algorithm of the conditional nonlinear local Lyapunov exponent(CNLLE)method.The eff... In order to quantify the influence of external forcings on the predictability limit using observational data,the author introduced an algorithm of the conditional nonlinear local Lyapunov exponent(CNLLE)method.The effectiveness of this algorithm is validated and compared with the nonlinear local Lyapunov exponent(NLLE)and signal-to-noise ratio methods using a coupled Lorenz model.The results show that the CNLLE method is able to capture the slow error growth constrained by external forcings,therefore,it can quantify the predictability limit induced by the external forcings.On this basis,a preliminary attempt was made to apply this method to measure the influence of ENSO on the predictability limit for both atmospheric and oceanic variable fields.The spatial distribution of the predictability limit induced by ENSO is similar to that arising from the initial conditions calculated by the NLLE method.This similarity supports ENSO as the major predictable signal for weather and climate prediction.In addition,a ratio of predictability limit(RPL)calculated by the CNLLE method to that calculated by the NLLE method was proposed.The RPL larger than 1 indicates that the external forcings can significantly benefit the long-term predictability limit.For instance,ENSO can effectively extend the predictability limit arising from the initial conditions of sea surface temperature over the tropical Indian Ocean by approximately four months,as well as the predictability limit of sea level pressure over the eastern and western Pacific Ocean.Moreover,the impact of ENSO on the geopotential height predictability limit is primarily confined to the troposphere. 展开更多
关键词 conditional nonlinear local Lyapunov exponent second-kind predictability coupled Lorenz model ENSO
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Novel cyber-physical collaborative detection and localization method against dynamic load altering attacks in smart energy grids
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作者 Xinyu Wang Xiangjie Wang +2 位作者 Xiaoyuan Luo Xinping Guan Shuzheng Wang 《Global Energy Interconnection》 EI CSCD 2024年第3期362-376,共15页
Owing to the integration of energy digitization and artificial intelligence technology,smart energy grids can realize the stable,efficient and clean operation of power systems.However,the emergence of cyber-physical a... Owing to the integration of energy digitization and artificial intelligence technology,smart energy grids can realize the stable,efficient and clean operation of power systems.However,the emergence of cyber-physical attacks,such as dynamic load-altering attacks(DLAAs)has introduced great challenges to the security of smart energy grids.Thus,this study developed a novel cyber-physical collaborative security framework for DLAAs in smart energy grids.The proposed framework integrates attack prediction in the cyber layer with the detection and localization of attacks in the physical layer.First,a data-driven method was proposed to predict the DLAA sequence in the cyber layer.By designing a double radial basis function network,the influence of disturbances on attack prediction can be eliminated.Based on the prediction results,an unknown input observer-based detection and localization method was further developed for the physical layer.In addition,an adaptive threshold was designed to replace the traditional precomputed threshold and improve the detection performance of the DLAAs.Consequently,through the collaborative work of the cyber-physics layer,injected DLAAs were effectively detected and located.Compared with existing methodologies,the simulation results on IEEE 14-bus and 118-bus power systems verified the superiority of the proposed cyber-physical collaborative detection and localization against DLAAs. 展开更多
关键词 Smart energy grids Cyber-physical system Dynamic load altering attacks Attack prediction Detection and localization
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A Review and Analysis of Localization Techniques in Underwater Wireless Sensor Networks 被引量:1
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作者 Seema Rani Anju +6 位作者 Anupma Sangwan Krishna Kumar Kashif Nisar Tariq Rahim Soomro Ag.Asri Ag.Ibrahim Manoj Gupta Laxmi Chandand Sadiq Ali Khan 《Computers, Materials & Continua》 SCIE EI 2023年第6期5697-5715,共19页
In recent years,there has been a rapid growth in Underwater Wireless Sensor Networks(UWSNs).The focus of research in this area is now on solving the problems associated with large-scale UWSN.One of the major issues in... In recent years,there has been a rapid growth in Underwater Wireless Sensor Networks(UWSNs).The focus of research in this area is now on solving the problems associated with large-scale UWSN.One of the major issues in such a network is the localization of underwater nodes.Localization is required for tracking objects and detecting the target.It is also considered tagging of data where sensed contents are not found of any use without localization.This is useless for application until the position of sensed content is confirmed.This article’s major goal is to review and analyze underwater node localization to solve the localization issues in UWSN.The present paper describes various existing localization schemes and broadly categorizes these schemes as Centralized and Distributed localization schemes underwater.Also,a detailed subdivision of these localization schemes is given.Further,these localization schemes are compared from different perspectives.The detailed analysis of these schemes in terms of certain performance metrics has been discussed in this paper.At the end,the paper addresses several future directions for potential research in improving localization problems of UWSN. 展开更多
关键词 Underwater wireless sensor networks localization schemes node localization ranging algorithms estimation based prediction based
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Impact of Perturbation Schemes on the Ensemble Prediction in a Coupled Lorenz Model 被引量:1
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作者 Qian ZOU Quanjia ZHONG +4 位作者 Jiangyu MAO Ruiqiang DING Deyu LU Jianping LI Xuan LI 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2023年第3期501-513,共13页
Based on a simple coupled Lorenz model,we investigate how to assess a suitable initial perturbation scheme for ensemble forecasting in a multiscale system involving slow dynamics and fast dynamics.Four initial perturb... Based on a simple coupled Lorenz model,we investigate how to assess a suitable initial perturbation scheme for ensemble forecasting in a multiscale system involving slow dynamics and fast dynamics.Four initial perturbation approaches are used in the ensemble forecasting experiments:the random perturbation(RP),the bred vector(BV),the ensemble transform Kalman filter(ETKF),and the nonlinear local Lyapunov vector(NLLV)methods.Results show that,regardless of the method used,the ensemble averages behave indistinguishably from the control forecasts during the first few time steps.Due to different error growth in different time-scale systems,the ensemble averages perform better than the control forecast after very short lead times in a fast subsystem but after a relatively long period of time in a slow subsystem.Due to the coupled dynamic processes,the addition of perturbations to fast variables or to slow variables can contribute to an improvement in the forecasting skill for fast variables and slow variables.Regarding the initial perturbation approaches,the NLLVs show higher forecasting skill than the BVs or RPs overall.The NLLVs and ETKFs had nearly equivalent prediction skill,but NLLVs performed best by a narrow margin.In particular,when adding perturbations to slow variables,the independent perturbations(NLLVs and ETKFs)perform much better in ensemble prediction.These results are simply implied in a real coupled air–sea model.For the prediction of oceanic variables,using independent perturbations(NLLVs)and adding perturbations to oceanic variables are expected to result in better performance in the ensemble prediction. 展开更多
关键词 ensemble prediction nonlinear local Lyapunov vector(NLLV) ensemble transform Kalman filter(ETKF) coupled air-sea models
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Local polynomial prediction method of multivariate chaotic time series and its application 被引量:1
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作者 方芬 王海燕 《Journal of Southeast University(English Edition)》 EI CAS 2005年第2期229-232,共4页
To improve the prediction accuracy of chaotic time series, a new methodformed on the basis of local polynomial prediction is proposed. The multivariate phase spacereconstruction theory is utilized to reconstruct the p... To improve the prediction accuracy of chaotic time series, a new methodformed on the basis of local polynomial prediction is proposed. The multivariate phase spacereconstruction theory is utilized to reconstruct the phase space firstly, and on its basis, apolynomial function is applied to construct the prediction model, then the parameters of the modelaccording to the data matrix built with the embedding dimensions are estimated and a one-stepprediction value is calculated. An estimate and one-step prediction value is calculated. Finally,the mean squared root statistics are used to estimate the prediction effect. The simulation resultsobtained by the Lorenz system and the prediction results of the Shanghai composite index show thatthe local polynomial prediction errors of the multivariate chaotic time series are small and itsprediction accuracy is much higher than that of the univariate chaotic time series. 展开更多
关键词 chaotic time series phase space reconstruction local polynomial prediction stock market
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Link prediction based on a semi-local similarity index 被引量:13
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作者 白萌 胡柯 唐翌 《Chinese Physics B》 SCIE EI CAS CSCD 2011年第12期498-504,共7页
Missing link prediction provides significant instruction for both analysis of network structure and mining of unknown links in incomplete networks. Recently, many algorithms have been proposed based on various node-si... Missing link prediction provides significant instruction for both analysis of network structure and mining of unknown links in incomplete networks. Recently, many algorithms have been proposed based on various node-similarity measures. Among these measures, the common neighbour index, the resource allocation index, and the local path index, stemming from different source, have been proved to have relatively high accuracy and low computational effort. In this paper, we propose a similarity index by combining the resource allocation index and the local path index. Simulation results on six unweighted networks show that the accuracy of the proposed index is higher than that of the local path one. Based on the same idea of the present index, we develop its corresponding weighted version and test it on several weighted networks. It is found that, except for the USAir network, the weighted variant also performs better than both the weighted resource allocation index and the weighted local path index. Due to the improved accuracy and the still low computational complexity, the indices may be useful for link prediction. 展开更多
关键词 link prediction resource allocation local path
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New prediction of chaotic time series based on local Lyapunov exponent 被引量:9
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作者 张勇 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第5期191-197,共7页
A new method of predicting chaotic time series is presented based on a local Lyapunov exponent, by quantitatively measuring the exponential rate of separation or attraction of two infinitely close trajectories in stat... A new method of predicting chaotic time series is presented based on a local Lyapunov exponent, by quantitatively measuring the exponential rate of separation or attraction of two infinitely close trajectories in state space. After recon- structing state space from one-dimensional chaotic time series, neighboring multiple-state vectors of the predicting point are selected to deduce the prediction formula by using the definition of the locaI Lyapunov exponent. Numerical simulations are carded out to test its effectiveness and verify its higher precision over two older methods. The effects of the number of referential state vectors and added noise on forecasting accuracy are also studied numerically. 展开更多
关键词 chaotic time series prediction of chaotic time series local Lyapunov exponent least squaresmethod
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The improved local linear prediction of chaotic time series 被引量:2
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作者 孟庆芳 彭玉华 孙佳 《Chinese Physics B》 SCIE EI CAS CSCD 2007年第11期3220-3225,共6页
Based on the Bayesian information criterion, this paper proposes the improved local linear prediction method to predict chaotic time series. This method uses spatial correlation and temporal correlation simultaneously... Based on the Bayesian information criterion, this paper proposes the improved local linear prediction method to predict chaotic time series. This method uses spatial correlation and temporal correlation simultaneously. Simulation results show that the improved local linear prediction method can effectively make multi-step and one-step prediction of chaotic time series and the multi-step prediction performance and one-step prediction accuracy of the improved local linear prediction method are superior to those of the traditional local linear prediction method. 展开更多
关键词 local linear prediction Bayesian information criterion state space reconstruction chaotic time series
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Using position specific scoring matrix and auto covariance to predict protein subnuclear localization 被引量:2
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作者 Rong-Quan Xiao Yan-Zhi Guo +4 位作者 Yu-Hong Zeng Hai-Feng Tan Hai-Feng Tan Xue-Mei Pu Meng-Long Li 《Journal of Biomedical Science and Engineering》 2009年第1期51-56,共6页
The knowledge of subnuclear localization in eukaryotic cells is indispensable for under-standing the biological function of nucleus, genome regulation and drug discovery. In this study, a new feature representation wa... The knowledge of subnuclear localization in eukaryotic cells is indispensable for under-standing the biological function of nucleus, genome regulation and drug discovery. In this study, a new feature representation was pro-posed by combining position specific scoring matrix (PSSM) and auto covariance (AC). The AC variables describe the neighboring effect between two amino acids, so that they incorpo-rate the sequence-order information;PSSM de-scribes the information of biological evolution of proteins. Based on this new descriptor, a support vector machine (SVM) classifier was built to predict subnuclear localization. To evaluate the power of our predictor, the benchmark dataset that contains 714 proteins localized in nine subnuclear compartments was utilized. The total jackknife cross validation ac-curacy of our method is 76.5%, that is higher than those of the Nuc-PLoc (67.4%), the OET- KNN (55.6%), AAC based SVM (48.9%) and ProtLoc (36.6%). The prediction software used in this article and the details of the SVM parameters are freely available at http://chemlab.scu.edu.cn/ predict_SubNL/index.htm and the dataset used in our study is from Shen and Chou’s work by downloading at http://chou.med.harvard.edu/ bioinf/Nuc-PLoc/Data.htm. 展开更多
关键词 POSITION Specific SCORING Matrix AUTO COVARIANCE Support Vector Machine Protein SUBNUCLEAR localization prediction
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The Dynamics of Changes in Starch and Lipid Droplets and Sub-Cellular Localization of β-Amylase During the Growth of Lily Bulbs 被引量:1
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作者 WU Sha-sha WU Jin-di +2 位作者 JIAO Xue-hui ZHANG Qi-xiang LV Ying-min 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2012年第4期585-592,共8页
The ultra-structure of mother and outer daughter scales of Lilium Oriental hybrid Sorbonne were studied using transmission electron microscope to examine the sub-cellular localization of starch and lipid droplets duri... The ultra-structure of mother and outer daughter scales of Lilium Oriental hybrid Sorbonne were studied using transmission electron microscope to examine the sub-cellular localization of starch and lipid droplets during growth and development from shoot emergence to senescence.The contents of starch granules and lipid droplets in the cell of the mother scales decreased significantly from shoot emergence to anthesis,indicating that these scales served as a source for growth and development.After flowering,the number of starch granules and lipid droplets increased dramatically,and finally the cells were filled with the above molecules indicating that the bulb becomes a major sink during bulb enlargement.Ultrastructure observation also showed that symplastic pathway is the main pathway in cells in the exchange and transportation of material during bulb development.The activity of β-amylase,one of the key enzymes catalyzing starch breakdown,showed a similar trend.The enzyme sub-cellular localization via immune-gold electron-microscopy showed that βamylase was predominantly located together with starch granules,while the gold particles were scarcely found in other sub-cellular compartments.The result suggested that this enzyme is compartmented together with its functional substrate supporting its function in catalyzing starch breakdown in living plant cells. 展开更多
关键词 Lilium Oriental hybrids BULB scale source and sink ULTRA-STRUCTURE Β-AMYLASE sub-cellular localization
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The Predictability Limit of Oceanic Mesoscale Eddy Tracks in the South China Sea
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作者 Hailong LIU Pingxiang CHU +5 位作者 Yao MENG Mengrong DING Pengfei LIN Ruiqiang DING Pengfei WANG Weipeng ZHENG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第9期1661-1679,共19页
Employing the nonlinear local Lyapunov exponent (NLLE) technique, this study assesses the quantitative predictability limit of oceanic mesoscale eddy (OME) tracks utilizing three eddy datasets for both annual and seas... Employing the nonlinear local Lyapunov exponent (NLLE) technique, this study assesses the quantitative predictability limit of oceanic mesoscale eddy (OME) tracks utilizing three eddy datasets for both annual and seasonal means. Our findings reveal a discernible predictability limit of approximately 39 days for cyclonic eddies (CEs) and 44 days for anticyclonic eddies (AEs) within the South China Sea (SCS). The predictability limit is related to the OME properties and seasons. The long-lived, large-amplitude, and large-radius OMEs tend to have a higher predictability limit. The predictability limit of AE (CE) tracks is highest in autumn (winter) with 52 (53) days and lowest in spring (summer) with 40 (30) days. The spatial distribution of the predictability limit of OME tracks also has seasonal variations, further finding that the area of higher predictability limits often overlaps with periodic OMEs. Additionally, the predictability limit of periodic OME tracks is about 49 days for both CEs and AEs, which is 5-10 days higher than the mean values. Usually, in the SCS, OMEs characterized by high predictability limit values exhibit more extended and smoother trajectories and often move along the northern slope of the SCS. 展开更多
关键词 predictABILITY mesoscale eddy nonlinear local Lyapunov exponent South China Sea seasonal variability
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Explainable prediction of loan default based on machine learning models
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作者 Xu Zhu Qingyong Chu +2 位作者 Xinchang Song Ping Hu Lu Peng 《Data Science and Management》 2023年第3期123-133,共11页
Owing to the convenience of online loans,an increasing number of people are borrowing money on online platforms.With the emergence of machine learning technology,predicting loan defaults has become a popular topic.How... Owing to the convenience of online loans,an increasing number of people are borrowing money on online platforms.With the emergence of machine learning technology,predicting loan defaults has become a popular topic.However,machine learning models have a black-box problem that cannot be disregarded.To make the prediction model rules more understandable and thereby increase the user’s faith in the model,an explanatory model must be used.Logistic regression,decision tree,XGBoost,and LightGBM models are employed to predict a loan default.The prediction results show that LightGBM and XGBoost outperform logistic regression and decision tree models in terms of the predictive ability.The area under curve for LightGBM is 0.7213.The accuracies of LightGBM and XGBoost exceed 0.8.The precisions of LightGBM and XGBoost exceed 0.55.Simultaneously,we employed the local interpretable model-agnostic explanations approach to undertake an explainable analysis of the prediction findings.The results show that factors such as the loan term,loan grade,credit rating,and loan amount affect the predicted outcomes. 展开更多
关键词 Explainable prediction Machine learning Loan default local interpretable model-agnostic explanations
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KLT-based local linear prediction of chaotic time series
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作者 Meng Qingfang Peng Yuhua Chen Yuehui 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2009年第4期694-699,共6页
In the reconstructed phase space, based on the Karhunen-Loeve transformation (KLT), the new local linear prediction method is proposed to predict chaotic time series. & noise-free chaotic time series and a noise ad... In the reconstructed phase space, based on the Karhunen-Loeve transformation (KLT), the new local linear prediction method is proposed to predict chaotic time series. & noise-free chaotic time series and a noise added chaotic time series are analyzed. The simulation results show that the KLT-based local linear prediction method can effectively make one-step and multi-step prediction for chaotic time series, and the one-step and multi-step prediction accuracies of the KLT-based local linear prediction method are superior to that of the traditional local linear prediction. 展开更多
关键词 Karhunen-Loeve transformation local linear prediction phase space reconstruction chaotic time series.
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Expression and sub-cellular localization of leucine-rich repeats and immunoglobulin-like domains are related to antioxidant enzymes in human ependymoma and oligodendroglioma
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作者 Wei Yi Lin Liu +2 位作者 Okechi Humphrey Qianxue Chen Shulan Huang 《Neural Regeneration Research》 SCIE CAS CSCD 2011年第11期860-864,共5页
The current study investigated correlations between the expression of leucine-rich repeats and immunoglobulin-like domain 1 (LRIG1) and antioxidant enzymes and related proteins, including manganese superoxide dismut... The current study investigated correlations between the expression of leucine-rich repeats and immunoglobulin-like domain 1 (LRIG1) and antioxidant enzymes and related proteins, including manganese superoxide dismutase, glutamate cysteine ligase catalytic or regulatory subunit, thioredoxin and thioredoxin reductase, in both human ependymoma and oligodendroglioma. Results revealed that the cytoplasmic expression of LRIG1 was associated with expression of glutamate cysteine ligase catalytic subunit in the human ependymoma, while the nuclear expression of LRIG1 was associated with expression of thioredoxin reductase. In human oligodendroglioma, the cytoplasmic expression of LRIG1 was associated with expression of the glutamate cysteine ligase catalytic subunit. Both the nuclear and perinuclear expressions of LRIG1 were associated with expression of glutamate cysteine ligase regulatory subunit. These results indicated that several antioxidant enzymes and related proteins contributed to LRIG1 expression, and that these may participate in the antioxidation of the cells. 展开更多
关键词 leucine-rich repeats and immunoglobulin-like domain 1 sub-cellular localization EPENDYMOMA OLIGODENDROGLIOMA antioxidant enzymes
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Multi-model predictive control with local constraints based on model switching 被引量:3
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作者 Zhenkuang XUE Shaoyuan LI 《控制理论与应用(英文版)》 EI 2005年第2期150-156,共7页
Because model switching system is a typical form of Takagi-Sugeno(T-S) model which is an universal approximator of continuous nonlinear systems, we describe the model switching system as mixed logical dynamical (ML... Because model switching system is a typical form of Takagi-Sugeno(T-S) model which is an universal approximator of continuous nonlinear systems, we describe the model switching system as mixed logical dynamical (MLD) system and use it in model predictive control (MPC) in this paper. Considering that each local model is only valid in each local region,we add local constraints to local models. The stability of proposed multi-model predictive control (MMPC) algorithm is analyzed, and the performance of MMPC is also demonstrated on an inulti-multi-output(MIMO) simulated pH neutralization process. 展开更多
关键词 Multi-model predictive control local constraints Mixed logical dynamical system STABILITY
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Golgi localization and dynamics of hyaluronan binding protein 1 (HABP1/p32/C1QBP) during the cell cycle 被引量:3
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作者 Aniruddha SENGUPTA Bhaswati BANERJEE +1 位作者 Rakesh K. TYAGI Kasturi DATTA 《Cell Research》 SCIE CAS CSCD 2005年第3期183-186,共4页
Hyaluronan binding protein 1 (HABP1) is a negatively charged multifunctional mammalian protein with a unique structural fold. Despite the fact that HABP1 possesses mitochondrial localization signal, it has also been l... Hyaluronan binding protein 1 (HABP1) is a negatively charged multifunctional mammalian protein with a unique structural fold. Despite the fact that HABP1 possesses mitochondrial localization signal, it has also been localized to other cellular compartments. Using indirect immunofluorescence, we examined the sub-cellular localization of HABP1 and its dynamics during mitosis. We wanted to determine whether it distributes in any distinctive manner after mitotic nuclear envelope disassembly or is dispersed randomly throughout the cell. Our results reveal the golgi localization of HABP1 and demonstrate its complete dispersion throughout the cell during mitosis. This distinctive distribution pattern of HABP1 during mitosis resembles its ligand hyaluronan, suggesting that in concert with each other the two molecules play critical roles in this dynamic process. 展开更多
关键词 Hyaluronan Binding Protein 1 (HABP1) HYALURONAN sub-cellular localization GOLGI mitosis.
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Chaotic time series multi-step direct prediction with partial least squares regression 被引量:2
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作者 Liu Zunxiong Liu Jianhui 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2007年第3期611-615,共5页
Considering chaotic time series multi-step prediction, multi-step direct prediction model based on partial least squares (PLS) is proposed in this article, where PLS, the method for predicting a set of dependent var... Considering chaotic time series multi-step prediction, multi-step direct prediction model based on partial least squares (PLS) is proposed in this article, where PLS, the method for predicting a set of dependent variables forming a large set of predictors, is used to model the dynamic evolution between the space points and the corresponding future points. The model can eliminate error accumulation with the common single-step local model algorithm~ and refrain from the high multi-collinearity problem in the reconstructed state space with the increase of embedding dimension. Simulation predictions are done on the Mackey-Glass chaotic time series with the model. The satisfying prediction accuracy is obtained and the model efficiency verified. In the experiments, the number of extracted components in PLS is set with cross-validation procedure. 展开更多
关键词 chaotic series prediction multi-step local model partial least squares.
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Prediction of recurrence and prognosis in patients with hepatocellular carcinoma after resection by use of CLIP score 被引量:26
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作者 Wen He Zhao Zhi-Min Ma Xing-Ren Zhou Yi-Zheng Feng Bao-Shan Fang,Department of Oncosurgery,the First Affiliated Hospital,Zhejiang University,Medical College,Hangzhou 310003,Zhejiang Province,China 《World Journal of Gastroenterology》 SCIE CAS CSCD 2002年第2期237-242,共6页
AIM: The survival time of patients with hepatocellular carcinoma (HCC) after resection is hard to predict. Both residual liver function and tumor extension factors should be considered. A new scoring system has recent... AIM: The survival time of patients with hepatocellular carcinoma (HCC) after resection is hard to predict. Both residual liver function and tumor extension factors should be considered. A new scoring system has recently been proposed by the Cancer of the Liver Italian Program (CLIP). CLIP score was confirmed to be one of the best ways to stage patients with HCC. To our knowledge, however, the literature concerning the correlation between CLIP score and prognosis for patients with HCC after resection was not published. The aim of this study is to evaluate the recurrence and prognostic value of CLIP score for the patients with HCC after resection. METHODS: A retrospective survey was carried out in 174 patients undergoing resection of HCC from January 1986 to June 1998. Six patients who died in the hospital after operation and 11 patients with the recurrence of the disease were excluded at 1 month after hepatectomy. By the end of June 2001, 4 patients were lost and 153 patients with curative resection have been followed up for at least three years. Among 153 patients, 115 developed intrahepatic recurrence and 10 developed extrahepatic recurrence, whereas the other 28 remained free of recurrence. Recurrences were classified into early (【 or =3 year) and late (】3 year) recurrence. The CLIP score included the parameters involved in the Child-Pugh stage (0-2), plus macroscopic tumor morphology (0-2), AFP levels (0-1), and the presence or absence of portal thrombosis (0-1). By contrast, portal vein thrombosis was defined as the presence of tumor emboli within vascular channel analyzed by microscopic examination in this study. Risk factors for recurrence and prognostic factors for survival in each group were analyzed by the chi-square test, the Kaplan-Meier estimation and the COX proportional hazards model respectively. RESULTS: The 1-, 3-, 5-, 7-,and 10-year disease-free survival rates after curative resection of HCC were 57.2%, 28.3%, 23.5%, 18.8%, and 17.8%, respectively. Median survival time was 28, 10, 4, and 5 mo for CLIP score 0, 1, 2, 3, and 4 to 5, respectively. Early and late recurrence developed in 109 patients and 16 patients respectively. By the chi-square test, tumor size, microsatellite, venous invasion, tumor type (uninodular, multinodular, massive), tumor extension (【 or = or 】50% of liver parenchyma replaced by tumor), TNM stage, CLIP score, and resection margin were the risk factors for early recurrence, whereas CLIP score and Child-Pugh stage were significant risk factors for late recurrence. In univariate survival analysis, Child-Pugh stages, resection margin, tumor size, microsatellite, venous invasion, tumor type, tumor extension, TNM stages, and CLIP score were associated with prognosis. The multivariate analysis by COX proportional hazards model showed that the independent predictive factors of survival were resection margins and TNM stages. CONCLUSION: CLIP score has displayed a unique superiority in predicting the tumor early and late recurrence and prognosis in the patients with HCC after resection. 展开更多
关键词 Neoplasm Recurrence local ADOLESCENT Adult Aged Carcinoma Hepatocellular Child Disease-Free Survival Female Humans Liver Neoplasms Male Middle Aged Neoplasm Staging predictive Value of Tests PROGNOSIS Retrospective Studies Risk Factors
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