The significant point is the bidirectional interaction technique in FSI analysis while investigating subsea corrosion effect. By this way, pipe environment is accurately modelled and fluid effects are also considered....The significant point is the bidirectional interaction technique in FSI analysis while investigating subsea corrosion effect. By this way, pipe environment is accurately modelled and fluid effects are also considered. The effect of external corrosion defects on structural behaviour of a pipeline is studied by creating a nonlinear numerical model based on the finite element method according to ABAQUS analysis program. Corrosion losses of sections are obtained from experimental results and applied to the model. Numerical model is formed by a span of sub-sea pipeline that is subjected to environmental loads. Seismic and wind-generated irregular wave loads are considered as environmental loads. Irregular wave is represented with equivalent eight regular waves via FFT. The pipe is modelled according to two different types which are non-corroded(intact) and corroded(deteriorated) to demonstrate corrosion effects on it. The visible type of corrosion in marine environment is named ‘pitting' corrosion, in which the material loss is locally interpenetrated over the surface. By considering this situation, the corroded and non-corroded pipes are modelled as 3D solid elements. The main point is revealing how the subsea corrosion affects the structural behaviour of pipelines on the basis of implementation of experimental results to a model structure due to changes of stresses and displacement.展开更多
A practical approach is discussed for sub-sea pipeline monitoring and leak detection based on the real time transient model . The characteristic method of transient simulation is coupled with the Extended Kalman Filt...A practical approach is discussed for sub-sea pipeline monitoring and leak detection based on the real time transient model . The characteristic method of transient simulation is coupled with the Extended Kalman Filter to estimate the system state where the only observed data are inlet and outlet flow rate and pressure. Because EKF has a time variant track under the non-stationary stochastic process with additive Gaussian noise, the high sensitivity of RTTM to non-stationary operating condition is reduced. A leak location recursion estimation formula is presented based on the real time observed data. The results of 27 groups of test data indicate that the procedure presented is sensitive to a wide range of detectable leak sizes and has a low average relative error of leak location .展开更多
Using the software ANSYS-19.2/Explicit Dynamics,this study performedfinite-element modeling of the large-diameter steel pipeline cross-section for the Beineu-Bozoy-Shymkent gas pipeline with a non-through straight crac...Using the software ANSYS-19.2/Explicit Dynamics,this study performedfinite-element modeling of the large-diameter steel pipeline cross-section for the Beineu-Bozoy-Shymkent gas pipeline with a non-through straight crack,strengthened by steel wire wrapping.The effects of the thread tensile force of the steel winding in the form of single rings at the crack edges and the wires with different winding diameters and pitches were also studied.The results showed that the strengthening was preferably executed at a minimum value of the thread tensile force,which was 6.4%more effective than that at its maximum value.The analysis of the influence of the winding dia-meters showed that the equivalent stresses increased by 32%from the beginning of the crack growth until the wire broke.The increment in winding diameter decelerated the disclosure of the edge crack and reduced its length by 8.2%.The analysis of the influence of the winding pitch showed that decreasing the distance between the winding turns also led to a 33.6%reduction in the length of the straight crack and a 7.9%reduction in the maximum stres-ses on the strengthened pipeline cross-section.The analysis of the temperature effect on the pipeline material,within a range from-40℃ to+50℃,resulted in a crack length change of up to 5.8%.As the temperature dropped,the crack length decreased.Within such a temperature range,the maximum stresses were observed along the cen-tral area of the crack,which were equal to 413 MPa at+50℃ and 440 MPa at-40℃.The results also showed that the presence of the steel winding in the pipeline significantly reduced the length of crack propagation up to 8.4 times,depending on the temperature effect and design parameters of prestressing.This work integrated the existing methods for crack localization along steel gas pipelines.展开更多
During the production period of shale gas, proppant particles and rock debris are produced together,which will seriously erode the elbows of gathering pipelines. In response to this problem, this paper takes the elbow...During the production period of shale gas, proppant particles and rock debris are produced together,which will seriously erode the elbows of gathering pipelines. In response to this problem, this paper takes the elbow of the gathering pipeline in the Changning Shale Gas Field as an example to test the erosion rate and material removal mechanism of the test piece at different angles of the elbow through experiments and compares the four erosion models with the experimental results. Through analysis, it is found that the best prediction model for quartz sand-carbon steel erosion is the Oka model. Based on the Oka model, FLUENT software was used to simulate and analyze the law of erosion of the elbow of the gas gathering pipeline under different gas flow velocities, gas gathering pressure, particle size, length of L1,and bending directions of the elbow. And a spiral pipeline structure is proposed to reduce the erosion rate of the elbow under the same working conditions. The results show that this structure can reduce erosion by 34%.展开更多
Thickness measurement plays an important role in the monitoring of pipeline corrosion damage. However, the requirement for prior knowledge of the shear wave velocity in the pipeline material for popular ultrasonic thi...Thickness measurement plays an important role in the monitoring of pipeline corrosion damage. However, the requirement for prior knowledge of the shear wave velocity in the pipeline material for popular ultrasonic thickness measurement limits its widespread application. This paper proposes a method that utilizes cylindrical shear horizontal(SH) guided waves to estimate pipeline thickness without prior knowledge of shear wave velocity. The inversion formulas are derived from the dispersion of higher-order modes with the high-frequency approximation. The waveform of the example problems is simulated using the real-axis integral method. The data points on the dispersion curves are processed in the frequency domain using the wave-number method. These extracted data are then substituted into the derived formulas. The results verify that employing higher-order SH guided waves for the evaluation of thickness and shear wave velocity yields less than1% error. This method can be applied to both metallic and non-metallic pipelines, thus opening new possibilities for health monitoring of pipeline structures.展开更多
Due to their high reliability and cost-efficiency,submarine pipelines are widely used in offshore oil and gas resource engineering.Due to the interaction of waves,currents,seabed,and pipeline structures,the soil aroun...Due to their high reliability and cost-efficiency,submarine pipelines are widely used in offshore oil and gas resource engineering.Due to the interaction of waves,currents,seabed,and pipeline structures,the soil around submarine pipelines is prone to local scour,severely affecting their operational safety.With the Yellow River Delta as the research area and based on the renormalized group(RNG)k-εturbulence model and Stokes fifth-order wave theory,this study solves the Navier-Stokes(N-S)equation using the finite difference method.The volume of fluid(VOF)method is used to describe the fluid-free surface,and a threedimensional numerical model of currents and waves-submarine pipeline-silty sandy seabed is established.The rationality of the numerical model is verified using a self-built waveflow flume.On this basis,in this study,the local scour development and characteristics of submarine pipelines in the Yellow River Delta silty sandy seabed in the prototype environment are explored and the influence of the presence of pipelines on hydrodynamic features such as surrounding flow field,shear stress,and turbulence intensity is analyzed.The results indicate that(1)local scour around submarine pipelines can be divided into three stages:rapid scour,slow scour,and stable scour.The maximum scour depth occurs directly below the pipeline,and the shape of the scour pits is asymmetric.(2)As the water depth decreases and the pipeline suspension height increases,the scour becomes more intense.(3)When currents go through a pipeline,a clear stagnation point is formed in front of the pipeline,and the flow velocity is positively correlated with the depth of scour.This study can provide a valuable reference for the protection of submarine pipelines in this area.展开更多
Antibacterial resistance is a global health threat that requires further concrete action on the part of all countries.In this context,one of the biggest concerns is whether enough new antibacterial drugs are being dis...Antibacterial resistance is a global health threat that requires further concrete action on the part of all countries.In this context,one of the biggest concerns is whether enough new antibacterial drugs are being discovered and developed.Although several high-quality reviews on clinical antibacterial drug pipelines from a global perspective were published recently,none provides comprehensive information on original antibacterial drugs at clinical stages in China.In this review,we summarize the latest progress of novel antibacterial drugs approved for marketing and under clinical evaluation in China since 2019.Information was obtained by consulting official websites,searching commercial databases,retrieving literature,asking personnel from institutions or companies,and other means,and a considerable part of the data covered here has not been included in other reviews.As of June 30,2023,a total of 20 antibacterial projects from 17 Chinese pharmaceutical companies or developers were identified and updated.Among them,two new antibacterial drugs that belong to traditional antibiotic classes were approved by the National Medical Products Administration(NMPA)in China in 2019 and 2021,respectively,and 18 antibacterial agents are in clinical development,with one under regulatory evaluation,five in phase-3,six in phase-2,and six in phase-1.Most of the clinical candidates are new analogs or monocomponents of traditional antibacterial pharmacophore types,including two dual-acting hybrid antibiotics and a recombinant antibacterial protein.Overall,despite there being 17 antibacterial clinical candidates,our analysis indicates that there are still relatively few clinically differentiated antibacterial agents in stages of clinical development in China.Hopefully,Chinese pharmaceutical companies and institutions will develop more innovative and clinically differentiated candidates with good market potential in the future research and development(R&D)of original antibacterial drugs.展开更多
In 2023,two consecutive earthquakes exceeding a magnitude of 7 occurred in Türkiye,causing severe casualties and economic losses.The damage to critical urban infrastructure and building structures,including highw...In 2023,two consecutive earthquakes exceeding a magnitude of 7 occurred in Türkiye,causing severe casualties and economic losses.The damage to critical urban infrastructure and building structures,including highways,railroads,and water supply pipelines,was particularly severe in areas where these structures intersected the seismogenic fault.Critical infrastructure projects that traverse active faults are susceptible to the influence of fault movement,pulse velocity,and ground motions.In this study,we used a unique approach to analyze the acceleration records obtained from the seismic station array(9 strong ground motion stations)located along the East Anatolian Fault(the seismogenic fault of the MW7.8 mainshock of the 2023 Türkiye earthquake doublet).The acceleration records were filtered and integrated to obtain the velocity and displacement time histories.We used the results of an on-site investigation,jointly conducted by China Earthquake Administration and Türkiye’s AFAD,to analyze the distribution of PGA,PGV,and PGD recorded by the strong motion array of the East Anatolian Fault.We found that the maximum horizontal PGA in this earthquake was 3.0 g,and the maximum co-seismic surface displacement caused by the East Anatolian Fault rupture was 6.50 m.As the fault rupture propagated southwest,the velocity pulse caused by the directional effect of the rupture increased gradually,with the maximum PGA reaching 162.3 cm/s.We also discussed the seismic safety of critical infrastructure projects traversing active faults,using two case studies of water supply pipelines in Türkiye that were damaged by earthquakes.We used a three-dimensional finite element model of the PE(polyethylene)water pipeline at the Islahiye State Hospital and fault displacement observations obtained through on-site investigation to analyze pipeline failure mechanisms.We further investigated the effect of the fault-crossing angle on seismic safety of a pipeline,based on our analysis and the failure performance of the large-diameter Thames Water pipeline during the 1999 Kocaeli earthquake.The seismic method of buried pipelines crossing the fault was summarized.展开更多
针对流水线型逐次逼近模数转换器(Pipelined SAR ADC)中残差放大器的核心运放功耗过高,从而严重限制ADC能效上限的问题,本文提出了一种新型的基于CMOS开关的自偏置全差分环形放大器(CMOS Self-biased Fully Differential Ring Amplifier...针对流水线型逐次逼近模数转换器(Pipelined SAR ADC)中残差放大器的核心运放功耗过高,从而严重限制ADC能效上限的问题,本文提出了一种新型的基于CMOS开关的自偏置全差分环形放大器(CMOS Self-biased Fully Differential Ring Amplifier,CSFRA),来替代传统运放。CSFRA通过引入CMOS开关自偏置和全差分结构,同时在非放大时序中关断电路,降低了残差放大器功耗。基于所提CSFRA,配合可降低开关功耗的检测和跳过切换方案,设计了一款12 Bit 10 MS/s的Pipelined SAR ADC。该电路基于MXIC L18B 180 nm CMOS工艺实现,实验结果表明,在10 MS/s的采样率下,该电路的SFDR和SNDR分别为75.3 dB和61.3 dB,功耗仅为944μW,其中CSFRA功耗仅为368μW。展开更多
Synchrotron microscopic data commonly suffer from poor image quality with degraded resolution incurred by instrumentation defects or experimental conditions.Image restoration methods are often applied to recover the r...Synchrotron microscopic data commonly suffer from poor image quality with degraded resolution incurred by instrumentation defects or experimental conditions.Image restoration methods are often applied to recover the reduced resolution,providing improved image details that can greatly facilitate scientific discovery.Among these methods,deconvolution techniques are straightforward,yet either require known prior information or struggle to tackle large experimental data.Deep learning(DL)-based super-resolution(SR)methods handle large data well,however data scarcity and model generalizability are problematic.In addition,current image restoration methods are mostly offline and inefficient for many beamlines where high data volumes and data complexity issues are encountered.To overcome these limitations,an online image-restoration pipeline that adaptably selects suitable algorithms and models from a method repertoire is promising.In this study,using both deconvolution and pretrained DL-based SR models,we show that different restoration efficacies can be achieved on different types of synchrotron experimental data.We describe the necessity,feasibility,and significance of constructing such an image-restoration pipeline for future synchrotron experiments.展开更多
Natural gas hydrate(NGH)can cause pipeline blockages during the transportation of oil and gas under high pressures and low temperatures.Reducing hydrate adhesion on pipelines is viewed as an efficient way to prevent N...Natural gas hydrate(NGH)can cause pipeline blockages during the transportation of oil and gas under high pressures and low temperatures.Reducing hydrate adhesion on pipelines is viewed as an efficient way to prevent NGH blockages.Previous studies suggested the water film can greatly increase hydrate adhesion in gas-dominant system.Herein,by performing the molecular dynamics simulations,we find in water-dominant system,the water film plays different roles in hydrate deposition on Fe and its corrosion surfaces.Specifically,due to the strong affinity of water on Fe surface,the deposited hydrate cannot convert the adsorbed water into hydrate,thus,a water film exists.As water affinities decrease(Fe>Fe_(2)O_(3)>FeO>Fe_(3)O_(4)),adsorbed water would convert to amorphous hydrate on Fe_(2)O_(3)and form the ordered hydrate on FeO and Fe_(3)O_(4)after hydrate deposition.While absorbed water film converts to amorphous or to hydrate,the adhesion strength of hydrate continuously increases(Fe<Fe_(2)O_(3)<FeO<Fe_(3)O_(4)).This is because the detachment of deposited hydrate prefers to occur at soft region of liquid layer,the process of which becomes harder as liquid layer vanishes.As a result,contrary to gas-dominant system,the water film plays the weakening roles on hydrate adhesion in water-dominant system.Overall,our results can help to better understand the hydrate deposition mechanisms on Fe and its corrosion surfaces and suggest hydrate deposition can be adjusted by changing water affinities on pipeline surfaces.展开更多
Transporting massive quantities of carbon dioxide through a pipeline in its supercritical state is extremely convenient.Because of the unique properties of supercritical carbon dioxide,however,leakage occurring in suc...Transporting massive quantities of carbon dioxide through a pipeline in its supercritical state is extremely convenient.Because of the unique properties of supercritical carbon dioxide,however,leakage occurring in such conditions can be extremely intricate,resulting in the dispersion area following leakage being influenced by numerous factors.In this study,this problem is addressed in the frame of the so-called Unified Dispersion Model(UDM),and various influential parameters are considered,namely,leakage pressure,leakage temperature,leakage aperture,leakage angle,atmospheric stability,wind speed,and surface roughness.The results show that the supercritical carbon dioxide dispersion is primarily influenced by high air temperatures,low wind speeds,reduced surface roughness,and release temperatures slightly below the critical temperature.Additionally,leak apertures also contribute to the dispersion.The dispersion is maximized under atmospheric stable D conditions,and when the leakage angle is 0°,the farthest downwind distance is 10 times greater than that at a leakage angle of 90°under the same conditions.展开更多
Pipeline transport of hydrogen is one of today’s economic and environmental challenges.In order to find safe and reliable application of both existing gas and build new pipelines,it is essential to carry out tests on...Pipeline transport of hydrogen is one of today’s economic and environmental challenges.In order to find safe and reliable application of both existing gas and build new pipelines,it is essential to carry out tests on full-scale pipeline section,including the potentially more dangerous places than the main pipe,the girth welds.For the investigations,pipeline sections of P355NH steel with girth welds were prepared and exposed to pure hydrogen at twice the maximum allowable operating pressure for 41 days.Subsequently,full-scale burst tests were carried out and specimens were cut and prepared from the typical locations of the failed pipeline sections for mechanical,and macro-and microstructural investigations.The results obtained were evaluated and compared with data from previous full-scale tests on pipeline sections without hydrogen exposure.The results showed differences in the behavior of pipeline sections loaded in different ways,with different characteristics of the materials and the welded joints,both in the cases without hydrogen exposure and in the cases exposed to hydrogen.展开更多
Repairs of corroded high-pressure pipelines are essential for fluids transportation under high pressure.One of the methods used in their repairs is the use of layered composites.The composite used must have the necess...Repairs of corroded high-pressure pipelines are essential for fluids transportation under high pressure.One of the methods used in their repairs is the use of layered composites.The composite used must have the necessary strength.Therefore,the experiments and analytical solutions presented in this paper are performed according to the relevant standards and codes,including ASME PCC-2,ASME B31.8S,ASME B31.4,ISO 24817 and ASME B31.G.In addition,the experimental tests are replicated numerically using the finite element method.Setting the strain gauges at different distances from the defect location,can reduce the nonlinear effects,deformation,and fluctuations due to the high pressure.The direct relationship between the depth of an axial defect and the stress concentration is observed at the inner side edges of the defect.Composite reparation reduces the non-linearities related to the sharp variation of the geometry and a more reliable numerical simulation could be performed.展开更多
Filling methods in the mining industry can maximize the recovery of mineral resources and protect the underground and surface environments.In recent years,such methods have been widely used in metal mines where pipeli...Filling methods in the mining industry can maximize the recovery of mineral resources and protect the underground and surface environments.In recent years,such methods have been widely used in metal mines where pipeline transportation typically plays a decisive role in the safety and stability of the entirefilling system.Because thefilling slurry contains a large percentage of solid coarse particles,the involved pipeline is typically eroded and often damaged during such a process.A possible solution is the so-called nesting repair technology.In the present study,nesting a 127 mm outer diameter pipeline in 151 mm inner diameter borehole is considered to meet the repair objective.First,by using the rheological theory,the pipeline transmission resistance and self-flow conveying range are calculated under different working conditions.It is shown that the pipeline transmission resistance is larger when the inner diameter of casing is 80 mm,and the limitflow rate of vertical pipeline self-flow is 120 m^(3)/h;moreover,when the pipeline diameter is 100 mm and theflow rate is 140 m^(3)/h,the self-flow conveying can be satisfied in most of the underground−455 m stage.Accordingly,a plan is presented for the nesting repair strategy,based on the installation of a drill bit under the casing and lowering the casing into the borehole as if it were a drill pipe.Finally,the outcomes of such a strategy are verified.Thefillingflow rate range using the new pipelines is found to be in the range from 188.60 to 224.39 m^(3)/h,and its averagefillingflow rate reaches 209.83 m^(3)/h when conveying 2319.6 m long-distance quarry.展开更多
A dent is a common type of defects for submarine pipeline.For submarine pipelines,high hydrostatic pressure and internal pressure are the main loads.Once pipelines bend due to complex subsea conditions,the compression...A dent is a common type of defects for submarine pipeline.For submarine pipelines,high hydrostatic pressure and internal pressure are the main loads.Once pipelines bend due to complex subsea conditions,the compression strain capacity may be exceeded.Research into the local buckling failure and accurate prediction of the compressive strain capacity are important.A finite element model of a pipeline with a dent is established.Local buckling failure under a bending moment is investigated,and the compressive strain capacity is calculated.The effects of different parameters on pipeline local buckling are analyzed.The results show that the dent depth,external pressure and internal pressure lead to different local buckling failure modes of the pipeline.A higher internal pressure indicates a larger compressive strain capacity,and the opposite is true for external pressure.When the ratio of external pressure to collapse pressure of intact pipeline is greater than 0.1,the deeper the dent,the greater the compressive strain capacity of the pipeline.And as the ratio is less than 0.1,the opposite is true.On the basis of these results,a regression equation for predicting the compressive strain capacity of a dented submarine pipeline is proposed,which can be referred to during the integrity assessment of a submarine pipeline.展开更多
文摘The significant point is the bidirectional interaction technique in FSI analysis while investigating subsea corrosion effect. By this way, pipe environment is accurately modelled and fluid effects are also considered. The effect of external corrosion defects on structural behaviour of a pipeline is studied by creating a nonlinear numerical model based on the finite element method according to ABAQUS analysis program. Corrosion losses of sections are obtained from experimental results and applied to the model. Numerical model is formed by a span of sub-sea pipeline that is subjected to environmental loads. Seismic and wind-generated irregular wave loads are considered as environmental loads. Irregular wave is represented with equivalent eight regular waves via FFT. The pipe is modelled according to two different types which are non-corroded(intact) and corroded(deteriorated) to demonstrate corrosion effects on it. The visible type of corrosion in marine environment is named ‘pitting' corrosion, in which the material loss is locally interpenetrated over the surface. By considering this situation, the corroded and non-corroded pipes are modelled as 3D solid elements. The main point is revealing how the subsea corrosion affects the structural behaviour of pipelines on the basis of implementation of experimental results to a model structure due to changes of stresses and displacement.
文摘A practical approach is discussed for sub-sea pipeline monitoring and leak detection based on the real time transient model . The characteristic method of transient simulation is coupled with the Extended Kalman Filter to estimate the system state where the only observed data are inlet and outlet flow rate and pressure. Because EKF has a time variant track under the non-stationary stochastic process with additive Gaussian noise, the high sensitivity of RTTM to non-stationary operating condition is reduced. A leak location recursion estimation formula is presented based on the real time observed data. The results of 27 groups of test data indicate that the procedure presented is sensitive to a wide range of detectable leak sizes and has a low average relative error of leak location .
基金funded by the Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan(Grant No.AP19680589).
文摘Using the software ANSYS-19.2/Explicit Dynamics,this study performedfinite-element modeling of the large-diameter steel pipeline cross-section for the Beineu-Bozoy-Shymkent gas pipeline with a non-through straight crack,strengthened by steel wire wrapping.The effects of the thread tensile force of the steel winding in the form of single rings at the crack edges and the wires with different winding diameters and pitches were also studied.The results showed that the strengthening was preferably executed at a minimum value of the thread tensile force,which was 6.4%more effective than that at its maximum value.The analysis of the influence of the winding dia-meters showed that the equivalent stresses increased by 32%from the beginning of the crack growth until the wire broke.The increment in winding diameter decelerated the disclosure of the edge crack and reduced its length by 8.2%.The analysis of the influence of the winding pitch showed that decreasing the distance between the winding turns also led to a 33.6%reduction in the length of the straight crack and a 7.9%reduction in the maximum stres-ses on the strengthened pipeline cross-section.The analysis of the temperature effect on the pipeline material,within a range from-40℃ to+50℃,resulted in a crack length change of up to 5.8%.As the temperature dropped,the crack length decreased.Within such a temperature range,the maximum stresses were observed along the cen-tral area of the crack,which were equal to 413 MPa at+50℃ and 440 MPa at-40℃.The results also showed that the presence of the steel winding in the pipeline significantly reduced the length of crack propagation up to 8.4 times,depending on the temperature effect and design parameters of prestressing.This work integrated the existing methods for crack localization along steel gas pipelines.
基金supported by the Petrochina's “14th Five-Year plan” Project(2021DJ2804)Sichuan Natural Science Foundation(2023NSFSC0422)。
文摘During the production period of shale gas, proppant particles and rock debris are produced together,which will seriously erode the elbows of gathering pipelines. In response to this problem, this paper takes the elbow of the gathering pipeline in the Changning Shale Gas Field as an example to test the erosion rate and material removal mechanism of the test piece at different angles of the elbow through experiments and compares the four erosion models with the experimental results. Through analysis, it is found that the best prediction model for quartz sand-carbon steel erosion is the Oka model. Based on the Oka model, FLUENT software was used to simulate and analyze the law of erosion of the elbow of the gas gathering pipeline under different gas flow velocities, gas gathering pressure, particle size, length of L1,and bending directions of the elbow. And a spiral pipeline structure is proposed to reduce the erosion rate of the elbow under the same working conditions. The results show that this structure can reduce erosion by 34%.
基金Project supported by the Natural Science Foundation of Jilin Province of China(Grant Nos.20240402081GH and 20220101012JC)the National Natural Science Foundation of China(Grant No.42074139)the State Key Laboratory of Acoustics,Chinese Academy of Sciences(Grant No.SKLA202308)。
文摘Thickness measurement plays an important role in the monitoring of pipeline corrosion damage. However, the requirement for prior knowledge of the shear wave velocity in the pipeline material for popular ultrasonic thickness measurement limits its widespread application. This paper proposes a method that utilizes cylindrical shear horizontal(SH) guided waves to estimate pipeline thickness without prior knowledge of shear wave velocity. The inversion formulas are derived from the dispersion of higher-order modes with the high-frequency approximation. The waveform of the example problems is simulated using the real-axis integral method. The data points on the dispersion curves are processed in the frequency domain using the wave-number method. These extracted data are then substituted into the derived formulas. The results verify that employing higher-order SH guided waves for the evaluation of thickness and shear wave velocity yields less than1% error. This method can be applied to both metallic and non-metallic pipelines, thus opening new possibilities for health monitoring of pipeline structures.
基金China Postdoctoral Science Foundation,Grant/Award Number:2023M731999National Natural Science Foundation of China,Grant/Award Number:52301326。
文摘Due to their high reliability and cost-efficiency,submarine pipelines are widely used in offshore oil and gas resource engineering.Due to the interaction of waves,currents,seabed,and pipeline structures,the soil around submarine pipelines is prone to local scour,severely affecting their operational safety.With the Yellow River Delta as the research area and based on the renormalized group(RNG)k-εturbulence model and Stokes fifth-order wave theory,this study solves the Navier-Stokes(N-S)equation using the finite difference method.The volume of fluid(VOF)method is used to describe the fluid-free surface,and a threedimensional numerical model of currents and waves-submarine pipeline-silty sandy seabed is established.The rationality of the numerical model is verified using a self-built waveflow flume.On this basis,in this study,the local scour development and characteristics of submarine pipelines in the Yellow River Delta silty sandy seabed in the prototype environment are explored and the influence of the presence of pipelines on hydrodynamic features such as surrounding flow field,shear stress,and turbulence intensity is analyzed.The results indicate that(1)local scour around submarine pipelines can be divided into three stages:rapid scour,slow scour,and stable scour.The maximum scour depth occurs directly below the pipeline,and the shape of the scour pits is asymmetric.(2)As the water depth decreases and the pipeline suspension height increases,the scour becomes more intense.(3)When currents go through a pipeline,a clear stagnation point is formed in front of the pipeline,and the flow velocity is positively correlated with the depth of scour.This study can provide a valuable reference for the protection of submarine pipelines in this area.
基金supported by the National Natural Science Foundation of China(32141003 and 82330110)the CAMS Innovation Fund for Medical Sciences(CIFMS+2 种基金2021-I2M-1-039)the National Science and Technology Infrastructure of China(National Pathogen Resource Center-NPRC-32)the Fundamental Research Funds for the Central Universities(2021-PT350-001).
文摘Antibacterial resistance is a global health threat that requires further concrete action on the part of all countries.In this context,one of the biggest concerns is whether enough new antibacterial drugs are being discovered and developed.Although several high-quality reviews on clinical antibacterial drug pipelines from a global perspective were published recently,none provides comprehensive information on original antibacterial drugs at clinical stages in China.In this review,we summarize the latest progress of novel antibacterial drugs approved for marketing and under clinical evaluation in China since 2019.Information was obtained by consulting official websites,searching commercial databases,retrieving literature,asking personnel from institutions or companies,and other means,and a considerable part of the data covered here has not been included in other reviews.As of June 30,2023,a total of 20 antibacterial projects from 17 Chinese pharmaceutical companies or developers were identified and updated.Among them,two new antibacterial drugs that belong to traditional antibiotic classes were approved by the National Medical Products Administration(NMPA)in China in 2019 and 2021,respectively,and 18 antibacterial agents are in clinical development,with one under regulatory evaluation,five in phase-3,six in phase-2,and six in phase-1.Most of the clinical candidates are new analogs or monocomponents of traditional antibacterial pharmacophore types,including two dual-acting hybrid antibiotics and a recombinant antibacterial protein.Overall,despite there being 17 antibacterial clinical candidates,our analysis indicates that there are still relatively few clinically differentiated antibacterial agents in stages of clinical development in China.Hopefully,Chinese pharmaceutical companies and institutions will develop more innovative and clinically differentiated candidates with good market potential in the future research and development(R&D)of original antibacterial drugs.
基金funded by the China National Key Research and Development Program(No.2022YFC3003505)the Fundamental Research Fund for the Central Public-interest Scientific Institutes(No.DQJB23Y01)+1 种基金the National Natural Science Foundation of China(No.52278540)the Fundamental Research Fund for the Central Public-interest Scientific Institutes(No.DQJB22B28).
文摘In 2023,two consecutive earthquakes exceeding a magnitude of 7 occurred in Türkiye,causing severe casualties and economic losses.The damage to critical urban infrastructure and building structures,including highways,railroads,and water supply pipelines,was particularly severe in areas where these structures intersected the seismogenic fault.Critical infrastructure projects that traverse active faults are susceptible to the influence of fault movement,pulse velocity,and ground motions.In this study,we used a unique approach to analyze the acceleration records obtained from the seismic station array(9 strong ground motion stations)located along the East Anatolian Fault(the seismogenic fault of the MW7.8 mainshock of the 2023 Türkiye earthquake doublet).The acceleration records were filtered and integrated to obtain the velocity and displacement time histories.We used the results of an on-site investigation,jointly conducted by China Earthquake Administration and Türkiye’s AFAD,to analyze the distribution of PGA,PGV,and PGD recorded by the strong motion array of the East Anatolian Fault.We found that the maximum horizontal PGA in this earthquake was 3.0 g,and the maximum co-seismic surface displacement caused by the East Anatolian Fault rupture was 6.50 m.As the fault rupture propagated southwest,the velocity pulse caused by the directional effect of the rupture increased gradually,with the maximum PGA reaching 162.3 cm/s.We also discussed the seismic safety of critical infrastructure projects traversing active faults,using two case studies of water supply pipelines in Türkiye that were damaged by earthquakes.We used a three-dimensional finite element model of the PE(polyethylene)water pipeline at the Islahiye State Hospital and fault displacement observations obtained through on-site investigation to analyze pipeline failure mechanisms.We further investigated the effect of the fault-crossing angle on seismic safety of a pipeline,based on our analysis and the failure performance of the large-diameter Thames Water pipeline during the 1999 Kocaeli earthquake.The seismic method of buried pipelines crossing the fault was summarized.
文摘针对流水线型逐次逼近模数转换器(Pipelined SAR ADC)中残差放大器的核心运放功耗过高,从而严重限制ADC能效上限的问题,本文提出了一种新型的基于CMOS开关的自偏置全差分环形放大器(CMOS Self-biased Fully Differential Ring Amplifier,CSFRA),来替代传统运放。CSFRA通过引入CMOS开关自偏置和全差分结构,同时在非放大时序中关断电路,降低了残差放大器功耗。基于所提CSFRA,配合可降低开关功耗的检测和跳过切换方案,设计了一款12 Bit 10 MS/s的Pipelined SAR ADC。该电路基于MXIC L18B 180 nm CMOS工艺实现,实验结果表明,在10 MS/s的采样率下,该电路的SFDR和SNDR分别为75.3 dB和61.3 dB,功耗仅为944μW,其中CSFRA功耗仅为368μW。
基金supported by the Beijing Natural Science Foundation(No.1234042)the National Key Research and Development Program for Young Scientists(No.2023YFA1609900)+1 种基金the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB37000000)the National Natural Science Foundation of China(No.12305371)。
文摘Synchrotron microscopic data commonly suffer from poor image quality with degraded resolution incurred by instrumentation defects or experimental conditions.Image restoration methods are often applied to recover the reduced resolution,providing improved image details that can greatly facilitate scientific discovery.Among these methods,deconvolution techniques are straightforward,yet either require known prior information or struggle to tackle large experimental data.Deep learning(DL)-based super-resolution(SR)methods handle large data well,however data scarcity and model generalizability are problematic.In addition,current image restoration methods are mostly offline and inefficient for many beamlines where high data volumes and data complexity issues are encountered.To overcome these limitations,an online image-restoration pipeline that adaptably selects suitable algorithms and models from a method repertoire is promising.In this study,using both deconvolution and pretrained DL-based SR models,we show that different restoration efficacies can be achieved on different types of synchrotron experimental data.We describe the necessity,feasibility,and significance of constructing such an image-restoration pipeline for future synchrotron experiments.
基金This work was supported by the National Natural Science Foundation of China(51874332,51991363)the CNPC's Major Science and Technology Projects(ZD2019-184-003)+1 种基金the Fundamental Research Funds for Central Universities(20CX05008A)“14th Five-Year plan”forward-looking basic major science and technology project of CNPC(2021DJ4901).
文摘Natural gas hydrate(NGH)can cause pipeline blockages during the transportation of oil and gas under high pressures and low temperatures.Reducing hydrate adhesion on pipelines is viewed as an efficient way to prevent NGH blockages.Previous studies suggested the water film can greatly increase hydrate adhesion in gas-dominant system.Herein,by performing the molecular dynamics simulations,we find in water-dominant system,the water film plays different roles in hydrate deposition on Fe and its corrosion surfaces.Specifically,due to the strong affinity of water on Fe surface,the deposited hydrate cannot convert the adsorbed water into hydrate,thus,a water film exists.As water affinities decrease(Fe>Fe_(2)O_(3)>FeO>Fe_(3)O_(4)),adsorbed water would convert to amorphous hydrate on Fe_(2)O_(3)and form the ordered hydrate on FeO and Fe_(3)O_(4)after hydrate deposition.While absorbed water film converts to amorphous or to hydrate,the adhesion strength of hydrate continuously increases(Fe<Fe_(2)O_(3)<FeO<Fe_(3)O_(4)).This is because the detachment of deposited hydrate prefers to occur at soft region of liquid layer,the process of which becomes harder as liquid layer vanishes.As a result,contrary to gas-dominant system,the water film plays the weakening roles on hydrate adhesion in water-dominant system.Overall,our results can help to better understand the hydrate deposition mechanisms on Fe and its corrosion surfaces and suggest hydrate deposition can be adjusted by changing water affinities on pipeline surfaces.
基金supported by the Postdoctoral Applied Research Project of Qingdao(Grant No.qdyy20210020).
文摘Transporting massive quantities of carbon dioxide through a pipeline in its supercritical state is extremely convenient.Because of the unique properties of supercritical carbon dioxide,however,leakage occurring in such conditions can be extremely intricate,resulting in the dispersion area following leakage being influenced by numerous factors.In this study,this problem is addressed in the frame of the so-called Unified Dispersion Model(UDM),and various influential parameters are considered,namely,leakage pressure,leakage temperature,leakage aperture,leakage angle,atmospheric stability,wind speed,and surface roughness.The results show that the supercritical carbon dioxide dispersion is primarily influenced by high air temperatures,low wind speeds,reduced surface roughness,and release temperatures slightly below the critical temperature.Additionally,leak apertures also contribute to the dispersion.The dispersion is maximized under atmospheric stable D conditions,and when the leakage angle is 0°,the farthest downwind distance is 10 times greater than that at a leakage angle of 90°under the same conditions.
基金supported by the European Union and the Hungarian State,co-financed by the European Structural and Investment Funds in the framework of the GINOP-2.3.4-15-2016-00004 project。
文摘Pipeline transport of hydrogen is one of today’s economic and environmental challenges.In order to find safe and reliable application of both existing gas and build new pipelines,it is essential to carry out tests on full-scale pipeline section,including the potentially more dangerous places than the main pipe,the girth welds.For the investigations,pipeline sections of P355NH steel with girth welds were prepared and exposed to pure hydrogen at twice the maximum allowable operating pressure for 41 days.Subsequently,full-scale burst tests were carried out and specimens were cut and prepared from the typical locations of the failed pipeline sections for mechanical,and macro-and microstructural investigations.The results obtained were evaluated and compared with data from previous full-scale tests on pipeline sections without hydrogen exposure.The results showed differences in the behavior of pipeline sections loaded in different ways,with different characteristics of the materials and the welded joints,both in the cases without hydrogen exposure and in the cases exposed to hydrogen.
文摘Repairs of corroded high-pressure pipelines are essential for fluids transportation under high pressure.One of the methods used in their repairs is the use of layered composites.The composite used must have the necessary strength.Therefore,the experiments and analytical solutions presented in this paper are performed according to the relevant standards and codes,including ASME PCC-2,ASME B31.8S,ASME B31.4,ISO 24817 and ASME B31.G.In addition,the experimental tests are replicated numerically using the finite element method.Setting the strain gauges at different distances from the defect location,can reduce the nonlinear effects,deformation,and fluctuations due to the high pressure.The direct relationship between the depth of an axial defect and the stress concentration is observed at the inner side edges of the defect.Composite reparation reduces the non-linearities related to the sharp variation of the geometry and a more reliable numerical simulation could be performed.
基金supported by the State Key Research Development Program of China(2018YFC0603705)the Fundamental Research Funds for the Central Universities(FRF-IDRYGD22-004).
文摘Filling methods in the mining industry can maximize the recovery of mineral resources and protect the underground and surface environments.In recent years,such methods have been widely used in metal mines where pipeline transportation typically plays a decisive role in the safety and stability of the entirefilling system.Because thefilling slurry contains a large percentage of solid coarse particles,the involved pipeline is typically eroded and often damaged during such a process.A possible solution is the so-called nesting repair technology.In the present study,nesting a 127 mm outer diameter pipeline in 151 mm inner diameter borehole is considered to meet the repair objective.First,by using the rheological theory,the pipeline transmission resistance and self-flow conveying range are calculated under different working conditions.It is shown that the pipeline transmission resistance is larger when the inner diameter of casing is 80 mm,and the limitflow rate of vertical pipeline self-flow is 120 m^(3)/h;moreover,when the pipeline diameter is 100 mm and theflow rate is 140 m^(3)/h,the self-flow conveying can be satisfied in most of the underground−455 m stage.Accordingly,a plan is presented for the nesting repair strategy,based on the installation of a drill bit under the casing and lowering the casing into the borehole as if it were a drill pipe.Finally,the outcomes of such a strategy are verified.Thefillingflow rate range using the new pipelines is found to be in the range from 188.60 to 224.39 m^(3)/h,and its averagefillingflow rate reaches 209.83 m^(3)/h when conveying 2319.6 m long-distance quarry.
基金financially supported by the National Natural Science Foundation of China(Grant No.52171285)。
文摘A dent is a common type of defects for submarine pipeline.For submarine pipelines,high hydrostatic pressure and internal pressure are the main loads.Once pipelines bend due to complex subsea conditions,the compression strain capacity may be exceeded.Research into the local buckling failure and accurate prediction of the compressive strain capacity are important.A finite element model of a pipeline with a dent is established.Local buckling failure under a bending moment is investigated,and the compressive strain capacity is calculated.The effects of different parameters on pipeline local buckling are analyzed.The results show that the dent depth,external pressure and internal pressure lead to different local buckling failure modes of the pipeline.A higher internal pressure indicates a larger compressive strain capacity,and the opposite is true for external pressure.When the ratio of external pressure to collapse pressure of intact pipeline is greater than 0.1,the deeper the dent,the greater the compressive strain capacity of the pipeline.And as the ratio is less than 0.1,the opposite is true.On the basis of these results,a regression equation for predicting the compressive strain capacity of a dented submarine pipeline is proposed,which can be referred to during the integrity assessment of a submarine pipeline.