Ten thiazoline compounds were synthesized starting from tetrahydrothiazoles. Their fungicidal activities against Phoma asparagi, Gibberella zeae, Cercospora beticola and Alteraria solani were examined. Some of them ga...Ten thiazoline compounds were synthesized starting from tetrahydrothiazoles. Their fungicidal activities against Phoma asparagi, Gibberella zeae, Cercospora beticola and Alteraria solani were examined. Some of them gave considerable good results.展开更多
A convenient and practicable method for the synthesis of the novel 2-（trifluoromethyl）-6-arylimidazo[2,1-b][1,3,4]-thiadiazole （bis-）Mannich base derivatives containing various substitutedpiperazine motif has been...A convenient and practicable method for the synthesis of the novel 2-（trifluoromethyl）-6-arylimidazo[2,1-b][1,3,4]-thiadiazole （bis-）Mannich base derivatives containing various substitutedpiperazine motif has been developed based on the fused-heterocycle intermediate. The new structures were identified through melting points, ^1H NMR, ^13C NMR, ^19F NMR, elemental analysis （or HRMS） and X-ray single-crystal diffraction. The pesticidal bioassays showed that some of compounds exhibited good fungicidal activities against Cercospora arachidicola, Physalospora piricola and Rhizoctonia cereali at 50 mg/L; some of them displayed favourable insecticidal activities against oriental armyworm （Mythimna separata Walker） at 200 rag/L, particularly, Vk and Vm with mortality rate of 75% and 80% respectively, could be considered as new insecticidal lead compounds for further structural optimization.展开更多
A series of novel pyrazole oxime derivatives containing oxazole ring were designed and synthesized. The title compounds were structurally confirmed by 1H NMR, 13C NMR spectra and elemental analyses. Preliminary bioass...A series of novel pyrazole oxime derivatives containing oxazole ring were designed and synthesized. The title compounds were structurally confirmed by 1H NMR, 13C NMR spectra and elemental analyses. Preliminary bioassay results showed that some of the title compounds displayed promising fungicidal activity besides insecticidal and acaricidal activity. Particularly, compound 8c exhibited potent fungicidal activity against cucumber Pseudoperonospora cubensis beyond good insecticidal activity against Aphis craccivora and Nilaparvata lugens.展开更多
文摘Ten thiazoline compounds were synthesized starting from tetrahydrothiazoles. Their fungicidal activities against Phoma asparagi, Gibberella zeae, Cercospora beticola and Alteraria solani were examined. Some of them gave considerable good results.
基金This work was supported by the National Key Research and Development Program of China （No. 2017YFD0200505）, the National Natural Science Foundation of China （Nos. 21372133 and 21772103）, and Tianjin Natural Science Foundation （No. 17JCYBJC19900）. We thank the teachers of the Biological Assay Center, Nankai University, for kind bioassay assistance of compounds.
文摘A convenient and practicable method for the synthesis of the novel 2-（trifluoromethyl）-6-arylimidazo[2,1-b][1,3,4]-thiadiazole （bis-）Mannich base derivatives containing various substitutedpiperazine motif has been developed based on the fused-heterocycle intermediate. The new structures were identified through melting points, ^1H NMR, ^13C NMR, ^19F NMR, elemental analysis （or HRMS） and X-ray single-crystal diffraction. The pesticidal bioassays showed that some of compounds exhibited good fungicidal activities against Cercospora arachidicola, Physalospora piricola and Rhizoctonia cereali at 50 mg/L; some of them displayed favourable insecticidal activities against oriental armyworm （Mythimna separata Walker） at 200 rag/L, particularly, Vk and Vm with mortality rate of 75% and 80% respectively, could be considered as new insecticidal lead compounds for further structural optimization.
基金funded by the National Natural Science Foundation of China (No.21202089)the Research Foundation of the Six People Peak of Jiangsu Province (Nos.2011-SWYY-009,2013-SWYY-013)the Technology Project Fund of Nantong City (Nos.AS2013004,CP12013002)
文摘A series of novel pyrazole oxime derivatives containing oxazole ring were designed and synthesized. The title compounds were structurally confirmed by 1H NMR, 13C NMR spectra and elemental analyses. Preliminary bioassay results showed that some of the title compounds displayed promising fungicidal activity besides insecticidal and acaricidal activity. Particularly, compound 8c exhibited potent fungicidal activity against cucumber Pseudoperonospora cubensis beyond good insecticidal activity against Aphis craccivora and Nilaparvata lugens.
