In this paper,the combined addition of copper or iron and sulphate ions onto TiO_(2) prepared by a simple sol-gel method is studied for formic acid photocatalytic conversion.A wide structural and morphological charact...In this paper,the combined addition of copper or iron and sulphate ions onto TiO_(2) prepared by a simple sol-gel method is studied for formic acid photocatalytic conversion.A wide structural and morphological characterization of the different photocatalysts was performed by X-ray diffraction(XRD),N_(2)-physisorption for BET surface area measurements,scanning and transmission electronic microscopies(SEM and TEM),UV-Vis diffuse spectroscopy(DRS)and X-ray photoelectron spectroscopy(XPS),in order to correlate the physico-chemical properties of the materials to their photocatalytic efficiencies for formic acid oxidation.Results have shown important differences among the catalysts depending on the metal added.Sulphated TiO_(2)/Cu(1%Cu)was the best photocatalyst obtaining about 100% formic acid conversion in only 5 min.The appropriate physico-chemical features of this photocatalyst,given by the addition of combined copper and sulphate ions,explain its excellence in photocatalytic reaction.展开更多
Supported γ-Al2O3 membranes without defects were prepared by the sol-gel procedure. The sol-gel method involved peptization of a boehmite (AlOOH) sol prepared from ammonium aluminium sulphate. The morphology of the s...Supported γ-Al2O3 membranes without defects were prepared by the sol-gel procedure. The sol-gel method involved peptization of a boehmite (AlOOH) sol prepared from ammonium aluminium sulphate. The morphology of the supported membranes was characterized by scanning electron microscopy (SEM) and 3D rotational microscopy. Furthermore, the effects of different preparing conditions on morphological characteristics of the membrane were also investigated. The results show that PVA is a good crack-preventing agent and the morphology of supported membranes is affected by many factors, such as Al2O3 and PVA contents of the sol, drying and sintering procedures and intrinsic defects on the substrate surface.展开更多
As an excellent chemical fertilizer,Potassium Sulphate(K2SO4)could provide both potassium and sulfur elements for crops.However,it is well known that potassium resource is very poor in China.To understand the Crystall...As an excellent chemical fertilizer,Potassium Sulphate(K2SO4)could provide both potassium and sulfur elements for crops.However,it is well known that potassium resource is very poor in China.To understand the Crystallization Kinetics(CK)of K2SO4could be conducive to utilize the limited potassium resource,promote the yield and purity of K2SO4.In this study saturated solution of potassium sulphate was prepared according to the phase diagram of Mg2+、展开更多
Potassium(K),an important nutrient element,can improve the stress resistance/tolerance of crops.The application of K in resisting plant-parasitic nematodes shows that the K treatment can reduce the occurrence of nemat...Potassium(K),an important nutrient element,can improve the stress resistance/tolerance of crops.The application of K in resisting plant-parasitic nematodes shows that the K treatment can reduce the occurrence of nematode diseases and increase crop yield.However,data on K_(2)SO_(4)induced rice resistance against the root-knot nematode Meloidogyne graminicola are still lacking.In this work,K_(2)SO_(4)treatment reduced galls and nematodes in rice plants and delayed the development of nematodes.Rather than affecting the attractiveness of roots to nematodes and the morphological phenotype of giant cells at feeding sites,such an effect is achieved by rapidly priming hydrogen peroxide(H_(2)O_(2))accumulation and increasing callose deposition.Meanwhile,galls and nematodes in rice roots were more in the potassium channel OsAKT11 and transporter OsHAK5 gene-deficient plants than in wild-type,while the K_(2)SO_(4)-induced resistance showed weaker in the defective plants.In addition,during the process of nematode infection,the expression of jasmonic acid(JA)/ethylene(ET)/brassinolide(BR)signaling pathway-related genes and pathogenesis-related(PR)genes OsPR1 a/OsPR1 b was up-regulated in rice after K_(2)SO_(4)treatment.In conclusion,K_(2)SO_(4)induced rice resistance against M.graminicola.The mechanism of inducing resistance was to prime the basal defense and required the participation of the K^(+)channel and transporter in rice.These laid a foundation for further study on the mechanism of rice defense against nematodes and the rational use of potassium fertilizer on improving rice resistance against nematodes in the field.展开更多
Large quantities of CO2 and blast furnace slag are discharged in the iron and steel industry. Mineral carbonation of blast furnace slag can offer substantial CO2 emission reduction and comprehensive utilization of the...Large quantities of CO2 and blast furnace slag are discharged in the iron and steel industry. Mineral carbonation of blast furnace slag can offer substantial CO2 emission reduction and comprehensive utilization of the solid waste. This paper describes a novel route for indirect mineral carbonation of titanium-bearing blast furnace （TBBF） slag, in which the TBBF slag is roasted with recyclable （NH4）2SO4 （AS） at low temperatures and converted into the sulphates of various valuable metals, including calcium, magnesium, aluminium and titanium. High value added Ti-and Al-rich products can be obtained through stepwise precipitation of the leaching solution from the roasted slag. The NH3 produced during the roasting is used to capture CO2 from flue gases. The NH4HCO3 and （NH4）2CO3 thus obtained are used to carbonate the CaSO4-containing leaching residue and MgSO4-rich leaching solution, respectively. In this study, the process parameters and efficiency for the roasting, carbonation and Ti and Al recovery were investigated in detail. The results showed that the sulfation ratios of calcium, magnesium, titanium and aluminium reached 92.6%, 87% and 84.4%, respectively, after roasting at an AS-to-TBBF slag mass ratio of 2：1 and 350℃ for 2 h. The leaching solution was subjected to hydrolysis at 102℃ for 4 h with a Ti hydrolysis ratio of 95.7%and the purity of TiO2 in the calcined hydrolysate reached 98 wt%. 99.7% of aluminium in the Ti-depleted leaching solution was precipitated by using NH3. The carbonation products of Ca and Mg were CaCO3 and （NH4）2Mg（CO3）2·4H2O, respectively. The latter can be decomposed into MgCO3 at 100-200℃ with simultaneous recovery of the NH3 for reuse. In this process, approximately 82.1% of Ca and 84.2% of Mg in the TBBF slag were transformed into stable carbonates and the total CO2 sequestration capacity per ton of TBBF slag reached up to 239.7 kg. The TiO2 obtained can be used directly as an end product, while the Al-rich precipitate and the two carbonation products can act, respectively, as raw materials for electrolytic aluminium, cement and light magnesium carbonate production for the replacement of natural resources.展开更多
目的:探讨聚乙二醇联合低剂量硫酸镁在2型糖尿病患者结肠镜肠道准备中的应用价值。方法:前瞻性纳入120例2型糖尿病结肠镜肠道准备患者,随机分为常规组和联合组两组,每组60例。常规组采用聚乙二醇3 L分割剂量方案,联合组在常规组方案基...目的:探讨聚乙二醇联合低剂量硫酸镁在2型糖尿病患者结肠镜肠道准备中的应用价值。方法:前瞻性纳入120例2型糖尿病结肠镜肠道准备患者,随机分为常规组和联合组两组,每组60例。常规组采用聚乙二醇3 L分割剂量方案,联合组在常规组方案基础上再口服50 ml 50%硫酸镁溶液。两组患者健康宣教和饮食调整方法相同。由一名单盲状态的内镜医师采用波士顿肠道准备评分量表(BBPS)评估两组患者肠道清洁质量,包括全结肠BBPS得分、肠道准备充分(BBPS≥6分,且各段结肠评分均≥2分)率、各段结肠(升结肠-盲肠段、横结肠-降结肠段、直肠-乙状结肠段)BBPS得分和BBPS<2分的比例,使用自制调查问卷评估两组患者肠道准备的耐受性和不良反应(恶心/呕吐、腹胀、腹痛、直肠烧灼感)。结果:联合组全结肠BBPS得分(7.7±1.3比7.1±1.5)、肠道准备充分率(90%比75%)显著高于常规组(P<0.05)。联合组升结肠-盲肠段(2.4±0.4比2.1±0.5)、横结肠-降结肠段(2.7±0.5比2.5±0.5)BBPS得分显著高于常规组(P<0.05),且上述2段结肠BBPS<2分患者比例(1.7%比11.7%;0比8.3%)显著低于常规组(P<0.05),两组直肠-乙状结肠段BBPS得分和BBPS<2分患者比例差异未见统计学意义(P>0.05)。两组肠道准备不良反应和耐受性差异未见统计学意义(P>0.05)。结论:聚乙二醇联合低剂量硫酸镁可以提高2型糖尿病患者结肠镜肠道准备质量,且并不增加不良反应发生风险。展开更多
The endothelin family has been related with several pathological diseases including cardiovascular disorders, hypertension and cancer. However, little is known about endothelin system in early stages of colorectal can...The endothelin family has been related with several pathological diseases including cardiovascular disorders, hypertension and cancer. However, little is known about endothelin system in early stages of colorectal cancer and there are no studies evaluating differences in proximal and distal colon segments. To deepen in this issue, we have studied the endothelin’s family gene and protein expression in normal mice and early stage of a mice model of Azoxymethane (AOM) and Dextran Sodium Sulphate (DSS) induced colorectal cancer in proximal and distal segments. Additionally, using nonlinear microscopy (NLM) techniques, we have characterized collagen changes in early stages of cancer disease development. In the present study, we have found significant differential gene expression and protein localization between these colon regions, which allow us to hypothesize a new role for the ET-2 as an early marker of colon cancer development.展开更多
Alumina membranes without pinholes and cracks were prepared by the sol-gel process using anunordum aluminium sulphate as the starting material. The effects of different preparing conditions on morphology characteristi...Alumina membranes without pinholes and cracks were prepared by the sol-gel process using anunordum aluminium sulphate as the starting material. The effects of different preparing conditions on morphology characteristics of the membrane were investigated by scanning electron microscopy and 3D rotational microscopy. The preparing conditions include the amounts of drying control chemical additives （DCCA）, sintering procedure and sol-gel concentration. The results showed that PVA is a good crack-preventing reagent and the morphology of supported membranes was affected by ninny factors, including Al2O3 concentration, PVA/Al2O3 ratio, heating rate, membrane thickness and intrinsic defects of the substrate surface.展开更多
Simulated compounds were prepared by loading K2SO4 onto V2O5/AC catalysts. Study the effect of K2SO4 on V1/AC catalysts in the presence of low concentration SO2. Transient response techniques, TPD was carried out. The...Simulated compounds were prepared by loading K2SO4 onto V2O5/AC catalysts. Study the effect of K2SO4 on V1/AC catalysts in the presence of low concentration SO2. Transient response techniques, TPD was carried out. The results indicated that the DeNO activity of V1/AC catalysts was decreased seriously in the early period of operation, but the deactivation was gradually diminished with SO2 adsorption and then, it was completely eliminated. For the sulphated catalysts (saturated catalysts by sulphate), their SCR activity were free from existence of gaseous SO2. the loss of activity about 10% caused by K2SO4 was found on them. The deactivation of K2SO4 deposited catalysts was due to the decrease of adsorbed and activated NH3, or some acid sites.展开更多
Objective:To study the relationship of serum human epididymis protein (HE4), cancer protein-2 (CP2) and human cartilage glycoprotein-39 (HCgp-39) levels with tumor malignancy in patients with endometrial carcinoma.Met...Objective:To study the relationship of serum human epididymis protein (HE4), cancer protein-2 (CP2) and human cartilage glycoprotein-39 (HCgp-39) levels with tumor malignancy in patients with endometrial carcinoma.Methods:A total of 90 patients with endometrial carcinoma treated in our hospital between May 2012 and August 2015 were collected and divided into early-to-mid (Ⅰ-Ⅲ stage) endometrial carcinoma group (n=59) and advanced (Ⅳ stage) endometrial carcinoma group (n=31) according to the pathological staging, and 34 patients with endometrial thickening who received uterine curettage in our hospital during the same period were selected as control group. The levels of HE4, CP2, HCgp-39 and tumor markers in serum as well as the mRNA expression of proliferation genes and invasion genes in tumor tissue were determined.Results:HE4, CP2, HCgp-39, CA125, CA19-9 and CEA levels in serum as well as Bcl2, Chk1, PIK1, HER2 and GDF-15 mRNA expression in tumor tissues of early-to-mid endometrial carcinoma group and advanced endometrial carcinoma group were significantly higher than those of control group while the miRNA-199a-3p, Bax, caspase3, BRCA1, Kiss-1 and KAI1 mRNA expression were lower than those of control group;HE4, CP2, HCgp-39, CA125, CA19-9 and CEA levels in serum as well as Bcl2, Chk1, PIK1, HER2 and GDF-15 mRNA expression in tumor tissues of advanced endometrial carcinoma group were significantly higher than those of early-to-mid endometrial carcinoma group while the miRNA-199a-3p, Bax, caspase3, BRCA1, Kiss-1 and KAI1 mRNA expression were lower than those of early-to-mid endometrial carcinoma group;serum HE4, CP2 and HCgp-39 levels were positively correlated with CA125, CA19-9, CEA, Bcl2, Chk1, PIK1, HER2 and GDF-15, and negatively correlated with miRNA-199a-3p, Bax, caspase3, BRCA1, Kiss-1 and KAI1. Conclusion:Serum HE4, CP2 and HCgp-39 levels can directly reflect the tumor malignancy in patients with endometrial carcinoma, and are expected to become the reliable means for tumor screening and treatment guidelines.展开更多
文摘In this paper,the combined addition of copper or iron and sulphate ions onto TiO_(2) prepared by a simple sol-gel method is studied for formic acid photocatalytic conversion.A wide structural and morphological characterization of the different photocatalysts was performed by X-ray diffraction(XRD),N_(2)-physisorption for BET surface area measurements,scanning and transmission electronic microscopies(SEM and TEM),UV-Vis diffuse spectroscopy(DRS)and X-ray photoelectron spectroscopy(XPS),in order to correlate the physico-chemical properties of the materials to their photocatalytic efficiencies for formic acid oxidation.Results have shown important differences among the catalysts depending on the metal added.Sulphated TiO_(2)/Cu(1%Cu)was the best photocatalyst obtaining about 100% formic acid conversion in only 5 min.The appropriate physico-chemical features of this photocatalyst,given by the addition of combined copper and sulphate ions,explain its excellence in photocatalytic reaction.
基金the National Natural Science Foundation of China (NSFC 20503015)
文摘Supported γ-Al2O3 membranes without defects were prepared by the sol-gel procedure. The sol-gel method involved peptization of a boehmite (AlOOH) sol prepared from ammonium aluminium sulphate. The morphology of the supported membranes was characterized by scanning electron microscopy (SEM) and 3D rotational microscopy. Furthermore, the effects of different preparing conditions on morphological characteristics of the membrane were also investigated. The results show that PVA is a good crack-preventing agent and the morphology of supported membranes is affected by many factors, such as Al2O3 and PVA contents of the sol, drying and sintering procedures and intrinsic defects on the substrate surface.
基金financial support of National Nature Science Foundation (21376178)TIDA giant growth plan (2011-XJR13020)+3 种基金Tianjin Science and technology support program (12ZCDZSF06900)Tianjin University of Science and Technology fund for scientific research (20120119)Tianjin education commission program (20130509)Research fund for the doctoral program of higher education of China(20131208120001)
文摘As an excellent chemical fertilizer,Potassium Sulphate(K2SO4)could provide both potassium and sulfur elements for crops.However,it is well known that potassium resource is very poor in China.To understand the Crystallization Kinetics(CK)of K2SO4could be conducive to utilize the limited potassium resource,promote the yield and purity of K2SO4.In this study saturated solution of potassium sulphate was prepared according to the phase diagram of Mg2+、
基金supported by the Natural Science Foundation of China(32172382,31801716,and 31571986)the National Key Research and Development Program of China(2021YFC2600404)the Scientific Research Project of Hunan Provincial Department of Education of China(19B259)。
文摘Potassium(K),an important nutrient element,can improve the stress resistance/tolerance of crops.The application of K in resisting plant-parasitic nematodes shows that the K treatment can reduce the occurrence of nematode diseases and increase crop yield.However,data on K_(2)SO_(4)induced rice resistance against the root-knot nematode Meloidogyne graminicola are still lacking.In this work,K_(2)SO_(4)treatment reduced galls and nematodes in rice plants and delayed the development of nematodes.Rather than affecting the attractiveness of roots to nematodes and the morphological phenotype of giant cells at feeding sites,such an effect is achieved by rapidly priming hydrogen peroxide(H_(2)O_(2))accumulation and increasing callose deposition.Meanwhile,galls and nematodes in rice roots were more in the potassium channel OsAKT11 and transporter OsHAK5 gene-deficient plants than in wild-type,while the K_(2)SO_(4)-induced resistance showed weaker in the defective plants.In addition,during the process of nematode infection,the expression of jasmonic acid(JA)/ethylene(ET)/brassinolide(BR)signaling pathway-related genes and pathogenesis-related(PR)genes OsPR1 a/OsPR1 b was up-regulated in rice after K_(2)SO_(4)treatment.In conclusion,K_(2)SO_(4)induced rice resistance against M.graminicola.The mechanism of inducing resistance was to prime the basal defense and required the participation of the K^(+)channel and transporter in rice.These laid a foundation for further study on the mechanism of rice defense against nematodes and the rational use of potassium fertilizer on improving rice resistance against nematodes in the field.
基金Supported by the National Key Projects for Fundamental Research and Development of China(2016YFB0600904)
文摘Large quantities of CO2 and blast furnace slag are discharged in the iron and steel industry. Mineral carbonation of blast furnace slag can offer substantial CO2 emission reduction and comprehensive utilization of the solid waste. This paper describes a novel route for indirect mineral carbonation of titanium-bearing blast furnace （TBBF） slag, in which the TBBF slag is roasted with recyclable （NH4）2SO4 （AS） at low temperatures and converted into the sulphates of various valuable metals, including calcium, magnesium, aluminium and titanium. High value added Ti-and Al-rich products can be obtained through stepwise precipitation of the leaching solution from the roasted slag. The NH3 produced during the roasting is used to capture CO2 from flue gases. The NH4HCO3 and （NH4）2CO3 thus obtained are used to carbonate the CaSO4-containing leaching residue and MgSO4-rich leaching solution, respectively. In this study, the process parameters and efficiency for the roasting, carbonation and Ti and Al recovery were investigated in detail. The results showed that the sulfation ratios of calcium, magnesium, titanium and aluminium reached 92.6%, 87% and 84.4%, respectively, after roasting at an AS-to-TBBF slag mass ratio of 2：1 and 350℃ for 2 h. The leaching solution was subjected to hydrolysis at 102℃ for 4 h with a Ti hydrolysis ratio of 95.7%and the purity of TiO2 in the calcined hydrolysate reached 98 wt%. 99.7% of aluminium in the Ti-depleted leaching solution was precipitated by using NH3. The carbonation products of Ca and Mg were CaCO3 and （NH4）2Mg（CO3）2·4H2O, respectively. The latter can be decomposed into MgCO3 at 100-200℃ with simultaneous recovery of the NH3 for reuse. In this process, approximately 82.1% of Ca and 84.2% of Mg in the TBBF slag were transformed into stable carbonates and the total CO2 sequestration capacity per ton of TBBF slag reached up to 239.7 kg. The TiO2 obtained can be used directly as an end product, while the Al-rich precipitate and the two carbonation products can act, respectively, as raw materials for electrolytic aluminium, cement and light magnesium carbonate production for the replacement of natural resources.
文摘目的:探讨聚乙二醇联合低剂量硫酸镁在2型糖尿病患者结肠镜肠道准备中的应用价值。方法:前瞻性纳入120例2型糖尿病结肠镜肠道准备患者,随机分为常规组和联合组两组,每组60例。常规组采用聚乙二醇3 L分割剂量方案,联合组在常规组方案基础上再口服50 ml 50%硫酸镁溶液。两组患者健康宣教和饮食调整方法相同。由一名单盲状态的内镜医师采用波士顿肠道准备评分量表(BBPS)评估两组患者肠道清洁质量,包括全结肠BBPS得分、肠道准备充分(BBPS≥6分,且各段结肠评分均≥2分)率、各段结肠(升结肠-盲肠段、横结肠-降结肠段、直肠-乙状结肠段)BBPS得分和BBPS<2分的比例,使用自制调查问卷评估两组患者肠道准备的耐受性和不良反应(恶心/呕吐、腹胀、腹痛、直肠烧灼感)。结果:联合组全结肠BBPS得分(7.7±1.3比7.1±1.5)、肠道准备充分率(90%比75%)显著高于常规组(P<0.05)。联合组升结肠-盲肠段(2.4±0.4比2.1±0.5)、横结肠-降结肠段(2.7±0.5比2.5±0.5)BBPS得分显著高于常规组(P<0.05),且上述2段结肠BBPS<2分患者比例(1.7%比11.7%;0比8.3%)显著低于常规组(P<0.05),两组直肠-乙状结肠段BBPS得分和BBPS<2分患者比例差异未见统计学意义(P>0.05)。两组肠道准备不良反应和耐受性差异未见统计学意义(P>0.05)。结论:聚乙二醇联合低剂量硫酸镁可以提高2型糖尿病患者结肠镜肠道准备质量,且并不增加不良反应发生风险。
文摘The endothelin family has been related with several pathological diseases including cardiovascular disorders, hypertension and cancer. However, little is known about endothelin system in early stages of colorectal cancer and there are no studies evaluating differences in proximal and distal colon segments. To deepen in this issue, we have studied the endothelin’s family gene and protein expression in normal mice and early stage of a mice model of Azoxymethane (AOM) and Dextran Sodium Sulphate (DSS) induced colorectal cancer in proximal and distal segments. Additionally, using nonlinear microscopy (NLM) techniques, we have characterized collagen changes in early stages of cancer disease development. In the present study, we have found significant differential gene expression and protein localization between these colon regions, which allow us to hypothesize a new role for the ET-2 as an early marker of colon cancer development.
基金Project supported by National Natural Science Foundation ofChina (Grant No .20373040) Science Foundation of Science andTechnology Commission of Zhejiang Province ( Grant No .0252nm101) Science Foundation of Shanghai MunicipalCommission of Science and Technology (Grant No .0452nm019)
文摘Alumina membranes without pinholes and cracks were prepared by the sol-gel process using anunordum aluminium sulphate as the starting material. The effects of different preparing conditions on morphology characteristics of the membrane were investigated by scanning electron microscopy and 3D rotational microscopy. The preparing conditions include the amounts of drying control chemical additives （DCCA）, sintering procedure and sol-gel concentration. The results showed that PVA is a good crack-preventing reagent and the morphology of supported membranes was affected by ninny factors, including Al2O3 concentration, PVA/Al2O3 ratio, heating rate, membrane thickness and intrinsic defects of the substrate surface.
文摘Simulated compounds were prepared by loading K2SO4 onto V2O5/AC catalysts. Study the effect of K2SO4 on V1/AC catalysts in the presence of low concentration SO2. Transient response techniques, TPD was carried out. The results indicated that the DeNO activity of V1/AC catalysts was decreased seriously in the early period of operation, but the deactivation was gradually diminished with SO2 adsorption and then, it was completely eliminated. For the sulphated catalysts (saturated catalysts by sulphate), their SCR activity were free from existence of gaseous SO2. the loss of activity about 10% caused by K2SO4 was found on them. The deactivation of K2SO4 deposited catalysts was due to the decrease of adsorbed and activated NH3, or some acid sites.
文摘Objective:To study the relationship of serum human epididymis protein (HE4), cancer protein-2 (CP2) and human cartilage glycoprotein-39 (HCgp-39) levels with tumor malignancy in patients with endometrial carcinoma.Methods:A total of 90 patients with endometrial carcinoma treated in our hospital between May 2012 and August 2015 were collected and divided into early-to-mid (Ⅰ-Ⅲ stage) endometrial carcinoma group (n=59) and advanced (Ⅳ stage) endometrial carcinoma group (n=31) according to the pathological staging, and 34 patients with endometrial thickening who received uterine curettage in our hospital during the same period were selected as control group. The levels of HE4, CP2, HCgp-39 and tumor markers in serum as well as the mRNA expression of proliferation genes and invasion genes in tumor tissue were determined.Results:HE4, CP2, HCgp-39, CA125, CA19-9 and CEA levels in serum as well as Bcl2, Chk1, PIK1, HER2 and GDF-15 mRNA expression in tumor tissues of early-to-mid endometrial carcinoma group and advanced endometrial carcinoma group were significantly higher than those of control group while the miRNA-199a-3p, Bax, caspase3, BRCA1, Kiss-1 and KAI1 mRNA expression were lower than those of control group;HE4, CP2, HCgp-39, CA125, CA19-9 and CEA levels in serum as well as Bcl2, Chk1, PIK1, HER2 and GDF-15 mRNA expression in tumor tissues of advanced endometrial carcinoma group were significantly higher than those of early-to-mid endometrial carcinoma group while the miRNA-199a-3p, Bax, caspase3, BRCA1, Kiss-1 and KAI1 mRNA expression were lower than those of early-to-mid endometrial carcinoma group;serum HE4, CP2 and HCgp-39 levels were positively correlated with CA125, CA19-9, CEA, Bcl2, Chk1, PIK1, HER2 and GDF-15, and negatively correlated with miRNA-199a-3p, Bax, caspase3, BRCA1, Kiss-1 and KAI1. Conclusion:Serum HE4, CP2 and HCgp-39 levels can directly reflect the tumor malignancy in patients with endometrial carcinoma, and are expected to become the reliable means for tumor screening and treatment guidelines.
