Background:Little is known about exercise cardiac power(ECP),defined as the ratio of directly measured maximal oxygen uptake with peak systolic blood pressure during exercise,on heart failure(HF)risk.We examined the a...Background:Little is known about exercise cardiac power(ECP),defined as the ratio of directly measured maximal oxygen uptake with peak systolic blood pressure during exercise,on heart failure(HF)risk.We examined the association of ECP and the risk of HF.Methods:This was a population-based cohort study of 2351 men from eastern Finland.The average time to follow-up was 25 years.Participants participated at baseline in an exercise stress test.A total of 313 cases of HF occurred.Results:Men with low ECP(<9.84 mL/mmHg,the lowest quartile)had a 2.37-fold(95%confidence interval(95%CI):1.68-3.35,p<0.0001)hazards ratio of HF as compared with men with high ECP(>13.92 mL/mmHg,the highest quartile),after adjusting for age.Low ECP was associated with a 1.96-fold risk(95%CI:1.38-2.78,p<0.001)of HF after additional adjustment for conventional risk factors.After further adjustment for left ventricular hypertrophy,the results hardly changed(hazards ratio=1.87,95%CI:1.31-2.66,p<0.001).One SD increase in ECP(3.16 mL/mmHg)was associated with a decreased risk of HF by 28%(95%CI:17%-37%).Conclusion:ECP provides a noninvasive and easily available measure from cardiopulmonary exercise tests in predicting HF.However,ECP did not provide additional value over maximal oxygen uptake.展开更多
Intensive in-depth development of resources, centralized purchasing and gradually expand under the category of environment, this paper studies how to use information technology tools to construction quality supervisio...Intensive in-depth development of resources, centralized purchasing and gradually expand under the category of environment, this paper studies how to use information technology tools to construction quality supervision and management system that focuses on the quality of supervision and project management, quality control process management, quality monitoring statistics report management, platform management-related content in four areas. Through the construction quality supervision and management system, to better enhance the quality of electric power enterprise management level, to ensure that the material quality, quantity of time and supplies. strengthening quality supervision and management can not only effectively reduce material procurement costs, but also enhance the competitiveness of enterprises.展开更多
In order to ensure that law can be effectively implemented, Lenin started from social reality and construction of regime in Soviet Russia, and systematically analyzed value significance and system construction of lega...In order to ensure that law can be effectively implemented, Lenin started from social reality and construction of regime in Soviet Russia, and systematically analyzed value significance and system construction of legal supervision, based on which he proposed to establish unified legal supervision system to fulfill the functions of legal supervision. The paper starts with theoretical basis and content of Lenin' s legal supervision, and expounds the importance of legal supervision in Soviet Russia.展开更多
In the year of 1768,the country was sent into a nation wide panic by a sorcery case named"soul stealing"in China,to which the emperor,officials and civilians at that time all responded differently.Based on t...In the year of 1768,the country was sent into a nation wide panic by a sorcery case named"soul stealing"in China,to which the emperor,officials and civilians at that time all responded differently.Based on the"soul stealing"case,this paper gives an analysis of the political environment and the bureaucratic system to explore the motives driven by power involved in the proceedings of the case,and in doing so the paper attempts to provide insights into the implications of the ancient power system that makes possible the abuse of authority.展开更多
Objective:The aim of this study were to explore the effects of 12-week modern online and traditional offline exercise programs on physical function,frailty status,emotional,and social support of pre-frail older adults...Objective:The aim of this study were to explore the effects of 12-week modern online and traditional offline exercise programs on physical function,frailty status,emotional,and social support of pre-frail older adults.Methods:The traditional offline exercise programs were offered at a local community center,and the modern online programs were done partly at home and partly modern online.Sixty older adults were randomly allocated into the traditional offline group(n=30;66.96±4.43 years)and the modern online+traditional offline groups(n=30;65.85±5.61 years).The exercise programs for both groups included strength,balance,and gait exercises and were done twice/week for 60 min/session.We recorded the study parameters(demographic features,frailty,and physical function)at the baseline as well as at the end of the exercise program.Results:Maximum subjects observed a reversal of the pre-frail status with an increase in physical function and a decrease in fat mass in both groups;however,the CB group showed a relatively significant improvement in physical function.Conclusion:The modern online+traditional offline exercise programs were not only effective in improving the physical condition,but also enhanced psychological status,social support,and adherence.Thus,based on these results,modern online+traditional offline exercise programs were preferable for improving the overall health of pre-frail older adults.展开更多
The story goes back to October 24, 2003 when Xiong Dem-ing, a woman living in a poverty-stricken village in southwest China, was on herway back home with a sack of pig feed on her shoulder. She happened to meet Premie...The story goes back to October 24, 2003 when Xiong Dem-ing, a woman living in a poverty-stricken village in southwest China, was on herway back home with a sack of pig feed on her shoulder. She happened to meet Premier Wen Jiabao, who was visiting her village in Yunyang County, Chongqing展开更多
Power is the nucleus of social and political life. Effective restraint on and supervision over the operation of power is the fundamental way of preventing corruption of power, which at the same time constitutes an imp...Power is the nucleus of social and political life. Effective restraint on and supervision over the operation of power is the fundamental way of preventing corruption of power, which at the same time constitutes an important indication to democracy and its development in a given country. Looking forward to attaining the strategic goal of building a society of relative prosperity in all aspects, the Sixteenth National Congress of the Communist Party of China called for "strengthening the restraint of and supervision over power to ensure that power given by the people is truly used to promote the interests of the people." The call specifies, in explicit language, the target of institutionalizing socialist democracy characterized by standardized operations in accordance with legal procedures.展开更多
Background: Smokeless tobacco is widely used by athletes to enhance performance. Nicotine is a central nervous system stimulant and acts on cardiocirculatory and metabolic systems, involving tissue blood flow and cir...Background: Smokeless tobacco is widely used by athletes to enhance performance. Nicotine is a central nervous system stimulant and acts on cardiocirculatory and metabolic systems, involving tissue blood flow and circulatory vasoreactivity. The aim of this study was to investigate the effects of the oral smokeless tobacco (Swedish snus (SS)) on the perception of fatigue and time to exhaustion (TTE) during moderate-intensity aerobic exercise. Methods: Fourteen healthy non-tobacco male users were recruited for a double-blind, controlled crossover design (SS vs. snus placebo (SP)). Subjects were tested for 3 sessions: experimental session 1 (Exp 1) consisted of an incremental test to determine the maximal aerobic power out-put (Wmax), whereas Exp2 and Exp3 consisted of exercising at 65%Wmax until exhaustion in SS or SP conditions. During Exp2 and Exp3, muscle and cerebral oxygenation was assessed by means of near-infrared spectroscopy, and the rating of perceived exertion (RPE) was recorded. Results: Comparing SS with SP tests, significant differences (p 〈 0.05) were found in the values of cerebral (-3%) and muscular tissues oxygenation (-4%) in the first 30 min of exercise. The RPE values were not significantly different between the 2 conditions (SS vs. SP). No significant difference was found in TTE (SS: 54.25 ± 21.84 min; SP: 50.01 ± 17.03 min). Conclusion: This study showed that muscular and cerebral oxygenation increased significantly with snus administration during an endurance exercise until exhaustion, but this did not affect fatigue perception and TTE. The results showed that snus could not be considered an ergogenic substance in non-tobacco users.2018 Published by Elsevier B.V. on behalf of Shanghai University of Sport. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/).展开更多
AIM To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations.METHODS Ninety-nine kidney transplant recipients(KTRs) w...AIM To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations.METHODS Ninety-nine kidney transplant recipients(KTRs) were assigned to interventional exercise(Group A; n = 52) and a usual care cohort(Group B; n = 47). Blood and urine chemistry, exercise capacity, muscular strength, anthropometric measures and health-related quality of life(HRQo L) were assessed at baseline, and after 6 and 12 mo. Group A underwent a supervised training three times per week for 12 mo. Group B received only general recommendations about home-based physical activities.RESULTS Eighty-five KTRs completed the study(Group A, n = 44; Group B, n = 41). After 12 mo, renal function remained stable in both groups. Group A significantly increased maximum workload(+13 W, P = 0.0003), V'O2 peak(+3.1 mL/kg per minute, P = 0.0099), muscular strength in plantar flexor(+12 kg, P = 0.0368), height in the countermovement jump(+1.9 cm, P = 0.0293) and decreased in Body Mass Index(-0.5 kg/m^2, P = 0.0013). HRQo L significantly improved in physical function(P = 0.0019), physical-role limitations(P = 0.0321) and social functioning scales(P = 0.0346). Noimprovements were found in Group B.CONCLUSION Twelve-month of supervised aerobic and resistance training improves the physiological variables related to physical fitness and cardiovascular risks without consequences on renal function. Recommendations alone are not sufficient to induce changes in exercise capacity of KTRs. Our study is an example of collaborative working between transplant centres, sports medicine and exercise facilities.展开更多
The aim of the study was to investigate ACTN3 (ct-actinin-3) and AMPD1 (adenosine monophosphate deaminase) polymorphism and genotype combinations in Bulgarian athletes competing in various sports and the relation ...The aim of the study was to investigate ACTN3 (ct-actinin-3) and AMPD1 (adenosine monophosphate deaminase) polymorphism and genotype combinations in Bulgarian athletes competing in various sports and the relation to peak power output. A mixed group of athletes (n = 52) competing at national and international level and a matching genetic control group (n = 109) of volunteers were recruited. Participants were genotyped for ACTN3 and AMPD1 by polymerase chain reaction. There were no significant differences in ACTN3 genotype distribution between athletes performing Wingate test (38% RR, 46% RX, 16% XX) and controls (41.2% RR, 46% RX, 12.8% XX). AMPD1 distribution was (73% CC, 27% CT, 0% TT) and in controls (73.2% CC, 25% CT, 1.8% TT). Athletes performing Wingate test showed equal 33% frequency of RR/CC and RX/CC combination, and 12% RX/CT. Significantly higher (P 〈 0.05) peak power output (11.10 W kg1) was found in athletes with RX/CT combination compared to other combinations (range: 8.83-9.71 W kg-1) and in R-power (RR + RX) and C-power (CC + CT) dominant models (9.91 W kgl). Mean power was higher (P 〈 0.05) in RX/CT combination (8.93 W kg-1) compared to RR/CC (7.75 W kg-1) and RR/CT (7.95 W kgl). In conclusion, the low frequency of T AMPD1 allele in Bulgarian athletes might indicate that this mutant allele is related to the physical performance. The prevalence of R ACTN3 and C AMPD1 alleles suggests that they could contribute to anaerobic performance. Higher peak power in Wingate test is associated with RX/CT genotype combination and R- and C-power dominant models.展开更多
The tide of anti-corruption swept across China, anti-corruption within the Party is a top priority. It needs sound legal regulation, but now our country doesn' t have a specific law to regulate the Party, leading to ...The tide of anti-corruption swept across China, anti-corruption within the Party is a top priority. It needs sound legal regulation, but now our country doesn' t have a specific law to regulate the Party, leading to Party members has not been well constrained about the execution of the power. The author analyzes the necessity of making a Party law from the perspective of curbing corruption, and puts forward some suggestions on strengthening the supervision function of Party law.展开更多
Side-channel attacks based on supervised learning require that the attacker have complete control over the cryptographic device and obtain a large number of labeled power traces.However,in real life,this requirement i...Side-channel attacks based on supervised learning require that the attacker have complete control over the cryptographic device and obtain a large number of labeled power traces.However,in real life,this requirement is usually not met.In this paper,an attack algorithm based on collaborative learning is proposed.The algorithm only needs to use a small number of labeled power traces to cooperate with the unlabeled power trace to realize the attack to cryptographic device.By experimenting with the DPA contest V4 dataset,the results show that the algorithm can improve the accuracy by about 20%compared with the pure supervised learning in the case of using only 10 labeled power traces.展开更多
文摘Background:Little is known about exercise cardiac power(ECP),defined as the ratio of directly measured maximal oxygen uptake with peak systolic blood pressure during exercise,on heart failure(HF)risk.We examined the association of ECP and the risk of HF.Methods:This was a population-based cohort study of 2351 men from eastern Finland.The average time to follow-up was 25 years.Participants participated at baseline in an exercise stress test.A total of 313 cases of HF occurred.Results:Men with low ECP(<9.84 mL/mmHg,the lowest quartile)had a 2.37-fold(95%confidence interval(95%CI):1.68-3.35,p<0.0001)hazards ratio of HF as compared with men with high ECP(>13.92 mL/mmHg,the highest quartile),after adjusting for age.Low ECP was associated with a 1.96-fold risk(95%CI:1.38-2.78,p<0.001)of HF after additional adjustment for conventional risk factors.After further adjustment for left ventricular hypertrophy,the results hardly changed(hazards ratio=1.87,95%CI:1.31-2.66,p<0.001).One SD increase in ECP(3.16 mL/mmHg)was associated with a decreased risk of HF by 28%(95%CI:17%-37%).Conclusion:ECP provides a noninvasive and easily available measure from cardiopulmonary exercise tests in predicting HF.However,ECP did not provide additional value over maximal oxygen uptake.
文摘Intensive in-depth development of resources, centralized purchasing and gradually expand under the category of environment, this paper studies how to use information technology tools to construction quality supervision and management system that focuses on the quality of supervision and project management, quality control process management, quality monitoring statistics report management, platform management-related content in four areas. Through the construction quality supervision and management system, to better enhance the quality of electric power enterprise management level, to ensure that the material quality, quantity of time and supplies. strengthening quality supervision and management can not only effectively reduce material procurement costs, but also enhance the competitiveness of enterprises.
文摘In order to ensure that law can be effectively implemented, Lenin started from social reality and construction of regime in Soviet Russia, and systematically analyzed value significance and system construction of legal supervision, based on which he proposed to establish unified legal supervision system to fulfill the functions of legal supervision. The paper starts with theoretical basis and content of Lenin' s legal supervision, and expounds the importance of legal supervision in Soviet Russia.
基金supported by the Key Discipline of Administrative Law Project of Shanghai University of Political Science and Law at Colleges and Universities sponsored by the Central Finance
文摘In the year of 1768,the country was sent into a nation wide panic by a sorcery case named"soul stealing"in China,to which the emperor,officials and civilians at that time all responded differently.Based on the"soul stealing"case,this paper gives an analysis of the political environment and the bureaucratic system to explore the motives driven by power involved in the proceedings of the case,and in doing so the paper attempts to provide insights into the implications of the ancient power system that makes possible the abuse of authority.
基金This research was funded by Key Technology Research and Demonstration Application of Non-medical Sexual Health Promotion Services Major Project of Provincial Science and Technology Department(No.18030801133)the Program for graduates research of Bengbu Medical College(No.Byycx1940).
文摘Objective:The aim of this study were to explore the effects of 12-week modern online and traditional offline exercise programs on physical function,frailty status,emotional,and social support of pre-frail older adults.Methods:The traditional offline exercise programs were offered at a local community center,and the modern online programs were done partly at home and partly modern online.Sixty older adults were randomly allocated into the traditional offline group(n=30;66.96±4.43 years)and the modern online+traditional offline groups(n=30;65.85±5.61 years).The exercise programs for both groups included strength,balance,and gait exercises and were done twice/week for 60 min/session.We recorded the study parameters(demographic features,frailty,and physical function)at the baseline as well as at the end of the exercise program.Results:Maximum subjects observed a reversal of the pre-frail status with an increase in physical function and a decrease in fat mass in both groups;however,the CB group showed a relatively significant improvement in physical function.Conclusion:The modern online+traditional offline exercise programs were not only effective in improving the physical condition,but also enhanced psychological status,social support,and adherence.Thus,based on these results,modern online+traditional offline exercise programs were preferable for improving the overall health of pre-frail older adults.
文摘The story goes back to October 24, 2003 when Xiong Dem-ing, a woman living in a poverty-stricken village in southwest China, was on herway back home with a sack of pig feed on her shoulder. She happened to meet Premier Wen Jiabao, who was visiting her village in Yunyang County, Chongqing
文摘Power is the nucleus of social and political life. Effective restraint on and supervision over the operation of power is the fundamental way of preventing corruption of power, which at the same time constitutes an important indication to democracy and its development in a given country. Looking forward to attaining the strategic goal of building a society of relative prosperity in all aspects, the Sixteenth National Congress of the Communist Party of China called for "strengthening the restraint of and supervision over power to ensure that power given by the people is truly used to promote the interests of the people." The call specifies, in explicit language, the target of institutionalizing socialist democracy characterized by standardized operations in accordance with legal procedures.
基金supported by research funds allocated to the following departments at the University of Verona:Neurosciences,Biomedicine and Movement Sciences,and Diagnostic and Public Health
文摘Background: Smokeless tobacco is widely used by athletes to enhance performance. Nicotine is a central nervous system stimulant and acts on cardiocirculatory and metabolic systems, involving tissue blood flow and circulatory vasoreactivity. The aim of this study was to investigate the effects of the oral smokeless tobacco (Swedish snus (SS)) on the perception of fatigue and time to exhaustion (TTE) during moderate-intensity aerobic exercise. Methods: Fourteen healthy non-tobacco male users were recruited for a double-blind, controlled crossover design (SS vs. snus placebo (SP)). Subjects were tested for 3 sessions: experimental session 1 (Exp 1) consisted of an incremental test to determine the maximal aerobic power out-put (Wmax), whereas Exp2 and Exp3 consisted of exercising at 65%Wmax until exhaustion in SS or SP conditions. During Exp2 and Exp3, muscle and cerebral oxygenation was assessed by means of near-infrared spectroscopy, and the rating of perceived exertion (RPE) was recorded. Results: Comparing SS with SP tests, significant differences (p 〈 0.05) were found in the values of cerebral (-3%) and muscular tissues oxygenation (-4%) in the first 30 min of exercise. The RPE values were not significantly different between the 2 conditions (SS vs. SP). No significant difference was found in TTE (SS: 54.25 ± 21.84 min; SP: 50.01 ± 17.03 min). Conclusion: This study showed that muscular and cerebral oxygenation increased significantly with snus administration during an endurance exercise until exhaustion, but this did not affect fatigue perception and TTE. The results showed that snus could not be considered an ergogenic substance in non-tobacco users.2018 Published by Elsevier B.V. on behalf of Shanghai University of Sport. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/).
文摘AIM To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations.METHODS Ninety-nine kidney transplant recipients(KTRs) were assigned to interventional exercise(Group A; n = 52) and a usual care cohort(Group B; n = 47). Blood and urine chemistry, exercise capacity, muscular strength, anthropometric measures and health-related quality of life(HRQo L) were assessed at baseline, and after 6 and 12 mo. Group A underwent a supervised training three times per week for 12 mo. Group B received only general recommendations about home-based physical activities.RESULTS Eighty-five KTRs completed the study(Group A, n = 44; Group B, n = 41). After 12 mo, renal function remained stable in both groups. Group A significantly increased maximum workload(+13 W, P = 0.0003), V'O2 peak(+3.1 mL/kg per minute, P = 0.0099), muscular strength in plantar flexor(+12 kg, P = 0.0368), height in the countermovement jump(+1.9 cm, P = 0.0293) and decreased in Body Mass Index(-0.5 kg/m^2, P = 0.0013). HRQo L significantly improved in physical function(P = 0.0019), physical-role limitations(P = 0.0321) and social functioning scales(P = 0.0346). Noimprovements were found in Group B.CONCLUSION Twelve-month of supervised aerobic and resistance training improves the physiological variables related to physical fitness and cardiovascular risks without consequences on renal function. Recommendations alone are not sufficient to induce changes in exercise capacity of KTRs. Our study is an example of collaborative working between transplant centres, sports medicine and exercise facilities.
文摘The aim of the study was to investigate ACTN3 (ct-actinin-3) and AMPD1 (adenosine monophosphate deaminase) polymorphism and genotype combinations in Bulgarian athletes competing in various sports and the relation to peak power output. A mixed group of athletes (n = 52) competing at national and international level and a matching genetic control group (n = 109) of volunteers were recruited. Participants were genotyped for ACTN3 and AMPD1 by polymerase chain reaction. There were no significant differences in ACTN3 genotype distribution between athletes performing Wingate test (38% RR, 46% RX, 16% XX) and controls (41.2% RR, 46% RX, 12.8% XX). AMPD1 distribution was (73% CC, 27% CT, 0% TT) and in controls (73.2% CC, 25% CT, 1.8% TT). Athletes performing Wingate test showed equal 33% frequency of RR/CC and RX/CC combination, and 12% RX/CT. Significantly higher (P 〈 0.05) peak power output (11.10 W kg1) was found in athletes with RX/CT combination compared to other combinations (range: 8.83-9.71 W kg-1) and in R-power (RR + RX) and C-power (CC + CT) dominant models (9.91 W kgl). Mean power was higher (P 〈 0.05) in RX/CT combination (8.93 W kg-1) compared to RR/CC (7.75 W kg-1) and RR/CT (7.95 W kgl). In conclusion, the low frequency of T AMPD1 allele in Bulgarian athletes might indicate that this mutant allele is related to the physical performance. The prevalence of R ACTN3 and C AMPD1 alleles suggests that they could contribute to anaerobic performance. Higher peak power in Wingate test is associated with RX/CT genotype combination and R- and C-power dominant models.
文摘The tide of anti-corruption swept across China, anti-corruption within the Party is a top priority. It needs sound legal regulation, but now our country doesn' t have a specific law to regulate the Party, leading to Party members has not been well constrained about the execution of the power. The author analyzes the necessity of making a Party law from the perspective of curbing corruption, and puts forward some suggestions on strengthening the supervision function of Party law.
文摘Side-channel attacks based on supervised learning require that the attacker have complete control over the cryptographic device and obtain a large number of labeled power traces.However,in real life,this requirement is usually not met.In this paper,an attack algorithm based on collaborative learning is proposed.The algorithm only needs to use a small number of labeled power traces to cooperate with the unlabeled power trace to realize the attack to cryptographic device.By experimenting with the DPA contest V4 dataset,the results show that the algorithm can improve the accuracy by about 20%compared with the pure supervised learning in the case of using only 10 labeled power traces.