Hypoxia is a condition found commonly in several disorders,such as ischemia,asthma,anemia and neonatal hypoxia.Individuals subjected suddenly to high altitude or extreme exercise are also challenged to low oxygen(O2...Hypoxia is a condition found commonly in several disorders,such as ischemia,asthma,anemia and neonatal hypoxia.Individuals subjected suddenly to high altitude or extreme exercise are also challenged to low oxygen(O2)levels.Since the brain presents elevated basal O_2 consumption,this organ is readily affected by hypoxia.For this reason,展开更多
Along with the increasing life span, aging and related diseases have become a serious medical and social problem that has roused global attention. In this paper, under the guidance of traditional Chinese medicine (TC...Along with the increasing life span, aging and related diseases have become a serious medical and social problem that has roused global attention. In this paper, under the guidance of traditional Chinese medicine (TCM), the author raises a theory of "dysfunction of Sanjiao qi activity" based on the studies and discussions of classical literatures on Sanjiao theory by combining knowledge in modern integrative traditional Chinese and Western medicine for aging from his more than 30 years of experiences of clinical and experimental practices. The author also tries to explain the mechanisms for aging from the whole aspect of Sanjiao qi activity.展开更多
Objective To investigate the clinical outcomes of children with congenital heart disease (CHD) requiring extracorporeal membrane oxygenation (ECMO) and left ventricular assist device (LVAD) support after cardiac...Objective To investigate the clinical outcomes of children with congenital heart disease (CHD) requiring extracorporeal membrane oxygenation (ECMO) and left ventricular assist device (LVAD) support after cardiac surgery. Methods A total of 22 patients with CHD who required postcardiotomy mechanical circulatory support between March 2004 and March 2011 (85 months ) were analyzed retrospectively. Median age of the patients was 420 d ( 15 d - 4 years) and median weight was 3.4 kg ( 2 - 14. 5 kg ). Eight patients were put on ECMO, while 14 patients were placed on LVAD. Results Thirteen (59%) patients died and 9 (41% ) survived to discharge. In survivals, the duration of LVAD and the duration of ECMO were both shorter than those of nonsurvivals (P 〈 O. 05). The main complication was bleeding. Conclusion The earlier treatment and application of more advanced cardiac support devices for CHD patients are key factors for reducing complications.展开更多
基金Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)INCT-Excitoxicidade e Neuroprotecao and by FINEP research grant “Rede Instituto Brasileiro de Neurociencia (IBN-Net)” #01.06.0842-00
文摘Hypoxia is a condition found commonly in several disorders,such as ischemia,asthma,anemia and neonatal hypoxia.Individuals subjected suddenly to high altitude or extreme exercise are also challenged to low oxygen(O2)levels.Since the brain presents elevated basal O_2 consumption,this organ is readily affected by hypoxia.For this reason,
基金Supported by the National Natural Science Foundation of China (No.30630074)Specialized Research Fund for the Doctoral Program of Higher Education (No.20060063006)+1 种基金Special Item of Science and Technology Research,Department of Education (No.207006)Special Item of Tianjin City (No.05YFGDSF02300)
文摘Along with the increasing life span, aging and related diseases have become a serious medical and social problem that has roused global attention. In this paper, under the guidance of traditional Chinese medicine (TCM), the author raises a theory of "dysfunction of Sanjiao qi activity" based on the studies and discussions of classical literatures on Sanjiao theory by combining knowledge in modern integrative traditional Chinese and Western medicine for aging from his more than 30 years of experiences of clinical and experimental practices. The author also tries to explain the mechanisms for aging from the whole aspect of Sanjiao qi activity.
文摘Objective To investigate the clinical outcomes of children with congenital heart disease (CHD) requiring extracorporeal membrane oxygenation (ECMO) and left ventricular assist device (LVAD) support after cardiac surgery. Methods A total of 22 patients with CHD who required postcardiotomy mechanical circulatory support between March 2004 and March 2011 (85 months ) were analyzed retrospectively. Median age of the patients was 420 d ( 15 d - 4 years) and median weight was 3.4 kg ( 2 - 14. 5 kg ). Eight patients were put on ECMO, while 14 patients were placed on LVAD. Results Thirteen (59%) patients died and 9 (41% ) survived to discharge. In survivals, the duration of LVAD and the duration of ECMO were both shorter than those of nonsurvivals (P 〈 O. 05). The main complication was bleeding. Conclusion The earlier treatment and application of more advanced cardiac support devices for CHD patients are key factors for reducing complications.