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Prioritizing Maintenance Spare Parts Based on Supportability Analysis and Neural Network
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作者 胡起伟 贾希胜 +1 位作者 白永生 田霞 《Journal of Donghua University(English Edition)》 EI CAS 2015年第6期965-969,共5页
In order to facilitate spare parts management,an integrated approach of BP neural network and supportability analysis(SA)was proposed to evaluate the criticality of spare parts as well as to prioritize spare parts.Inf... In order to facilitate spare parts management,an integrated approach of BP neural network and supportability analysis(SA)was proposed to evaluate the criticality of spare parts as well as to prioritize spare parts.Influential factors of prioritizing spare parts were detailedly analyzed.Framework of the integrated method was established.The modelling process based on BP neural network was presented.As the input of the neural network,the values of influential factors were determined by supportability analysis data.Based on the presented method,spare parts could be automatically prioritized after supportability analysis for a new system.A case study results showed that the new method was applicable and effective. 展开更多
关键词 spare parts PRIORITIZATION neural network supportability analysis(SA)
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Catalyst–Support Interaction in Polyaniline‑Supported Ni_(3)Fe Oxide to Boost Oxygen Evolution Activities for Rechargeable Zn‑Air Batteries
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作者 Xiaohong Zou Qian Lu +8 位作者 Mingcong Tang Jie Wu Kouer Zhang Wenzhi Li Yunxia Hu Xiaomin Xu Xiao Zhang Zongping Shao Liang An 《Nano-Micro Letters》 SCIE EI CAS 2025年第1期176-190,共15页
Catalyst–support interaction plays a crucial role in improving the catalytic activity of oxygen evolution reaction(OER).Here we modulate the catalyst–support interaction in polyaniline-supported Ni_(3)Fe oxide(Ni_(3... Catalyst–support interaction plays a crucial role in improving the catalytic activity of oxygen evolution reaction(OER).Here we modulate the catalyst–support interaction in polyaniline-supported Ni_(3)Fe oxide(Ni_(3)Fe oxide/PANI)with a robust hetero-interface,which significantly improves oxygen evolution activities with an overpotential of 270 mV at 10 mA cm^(-2)and specific activity of 2.08 mA cm_(ECSA)^(-2)at overpotential of 300 mV,3.84-fold that of Ni_(3)Fe oxide.It is revealed that the catalyst–support interaction between Ni_(3)Fe oxide and PANI support enhances the Ni–O covalency via the interfacial Ni–N bond,thus promoting the charge and mass transfer on Ni_(3)Fe oxide.Considering the excellent activity and stability,rechargeable Zn-air batteries with optimum Ni_(3)Fe oxide/PANI are assembled,delivering a low charge voltage of 1.95 V to cycle for 400 h at 10 mA cm^(-2).The regulation of the effect of catalyst–support interaction on catalytic activity provides new possibilities for the future design of highly efficient OER catalysts. 展开更多
关键词 Catalyst-support interaction Supported catalysts HETEROINTERFACE Oxygen evolution reaction Zn-air batteries
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Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function
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作者 William J.Flerlage Mark L.Dell’Acqua +1 位作者 Brian M.Cox Fereshteh S.Nugent 《Neural Regeneration Research》 SCIE CAS 2025年第10期2913-2914,共2页
There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(Simmons... There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(Simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs). 展开更多
关键词 FUNCTION SUPPORTING
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Machine Learning Techniques in Predicting Hot Deformation Behavior of Metallic Materials
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作者 Petr Opela Josef Walek Jaromír Kopecek 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期713-732,共20页
In engineering practice,it is often necessary to determine functional relationships between dependent and independent variables.These relationships can be highly nonlinear,and classical regression approaches cannot al... In engineering practice,it is often necessary to determine functional relationships between dependent and independent variables.These relationships can be highly nonlinear,and classical regression approaches cannot always provide sufficiently reliable solutions.Nevertheless,Machine Learning(ML)techniques,which offer advanced regression tools to address complicated engineering issues,have been developed and widely explored.This study investigates the selected ML techniques to evaluate their suitability for application in the hot deformation behavior of metallic materials.The ML-based regression methods of Artificial Neural Networks(ANNs),Support Vector Machine(SVM),Decision Tree Regression(DTR),and Gaussian Process Regression(GPR)are applied to mathematically describe hot flow stress curve datasets acquired experimentally for a medium-carbon steel.Although the GPR method has not been used for such a regression task before,the results showed that its performance is the most favorable and practically unrivaled;neither the ANN method nor the other studied ML techniques provide such precise results of the solved regression analysis. 展开更多
关键词 Machine learning Gaussian process regression artificial neural networks support vector machine hot deformation behavior
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Correlation between anxiety, depression, and social stress in young patients with thoracolumbar spine fractures
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作者 Bo Wang Da Shi +1 位作者 Yin-Di Sun Bo Dong 《World Journal of Psychiatry》 SCIE 2025年第1期83-92,共10页
BACKGROUND Traumatic injuries,such as falling,car accidents,and crushing mostly cause spinal fractures in young and middle-aged people,and>50%of them are thoracolumbar fractures.This kind of fracture is easily comb... BACKGROUND Traumatic injuries,such as falling,car accidents,and crushing mostly cause spinal fractures in young and middle-aged people,and>50%of them are thoracolumbar fractures.This kind of fracture is easily combined with serious injuries to peripheral nerves and soft tissues,which causes paralysis of the lower limbs if there is no timely rehabilitation treatment.Young patients with thoracolumbar fractures find it difficult to recover after the operation,and they are prone to depression,low self-esteem,and other negative emotions.AIM To investigate the association between anxiety,depression,and social stress in young patients with thoracolumbar spine fractures and the effect on rehabilitation outcomes.METHODS This study retrospectively analyzed 100 patients admitted to the orthopedic department of Honghui Hospital,Xi’an Jiaotong University who underwent thoracolumbar spine fracture surgery from January 2022 to June 2023.The general data of the patients were assessed with the Hamilton anxiety scale(HAMA),Hamilton depression scale(HAMD),life events scale,and social support rating scale(SSRS)to identify the correlation between anxiety,depression scores,and social stress and social support.The Japanese Orthopedic Association(JOA)was utilized to evaluate the rehabilitation outcomes of the patients and to analyze the effects of anxiety and depression scores on rehabilitation.RESULTS According to the scores of HAMD and HAMA in all patients,the prevalence of depression in patients was 39%(39/100),and the prevalence of anxiety was 49%(49/100).Patients were categorized into non-depression(n=61)and depression(n=39),non-anxiety(n=51),and anxiety(n=49)groups.Statistically significant differences in gender,occupation,Pittsburgh Sleep Quality Index(PSQI)score,and monthly family income were observed between the non-depression and depression groups(P<0.05).A significant difference in occupation and PSQI score was found between the non-anxiety and anxiety groups.Both depression(r=0.207,P=0.038)and anxiety scores(r=0.473,P<0.001)were significantly and positively correlated with negative life events.The difference in negative life event scores as well as SSRS total and item scores was statist-ically significant between patients in the non-depression and depression groups(P<0.05).The difference between the non-anxiety and anxiety groups was statistically significant(P<0.05)in the negative life event scores as well as the total SSRS scores.Additionally,JOA scores were significantly lower in both anxious and depressed patients.CONCLUSION Young patients with thoracolumbar fractures are prone to anxiety and depression.Patients’anxiety and depression are closely associated with social pressure,which reduces the life pressure of young patients with thoracolumbar fractures,enhances social support,and improves the psychology of anxiety and depression.,which affects patients’recovery. 展开更多
关键词 Patients with thoracolumbar fractures ANXIETY DEPRESSION Social pressure Social support
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Enterprise application transformation strategy and roadmap design:A business value driven and IT supportability-based approach
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作者 Yale Yu Sharma Madiraju 《Journal of Management Analytics》 EI 2015年第2期111-120,共10页
This paper proposes a practical and framework-based approach to design an architecture transformation strategy and roadmap aiming to transform or modernize critical legacy enterprise systems.The approach is business v... This paper proposes a practical and framework-based approach to design an architecture transformation strategy and roadmap aiming to transform or modernize critical legacy enterprise systems.The approach is business value driven with IT supportability in terms of lower application operational and support costs,higher business value and shorter time to market of application delivery.The approach introduces a robust enterprise application architecture assessment framework with an emphasis on technical(internal)and strategic(external)perspectives to guide the application assessment and also a finance selfsupport transformation strategy to aid its transformation roadmap design.The approach was applied in multiple large enterprises successfully and received endorsements and positive feedback from the sponsors.The paper also presents a case study detailing the successful application of the approach to modernize an enterprise logistics transportation management system. 展开更多
关键词 application modernization application architecture assessment enterprise application architecture transformation IT supportability total cost of development and operation
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Coalbursts in China: Theory, practice and management 被引量:3
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作者 Yishan Pan Yimin Song +1 位作者 Hao Luo Yonghui Xiao 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第1期1-25,共25页
Coalburst is one of the most serious disasters that threaten the safe production of coal mines, and this disaster is particularly serious in China. This paper presents an overview of coalbursts in China since 1980s. F... Coalburst is one of the most serious disasters that threaten the safe production of coal mines, and this disaster is particularly serious in China. This paper presents an overview of coalbursts in China since 1980s. From the "stress and energy" and "regional and local" perspectives, the achievements in the theory, practice and management of coalbursts in China are systematically summarized. A theoretical system of coalbursts has been formed to reveal the deformational behavior of coalbursts and explain the mechanism of coalbursts. The occurrence conditions of coalbursts are put forward and the critical stress is obtained. The stress index method for risk evaluation of coalbursts before mining is proposed, and the deformation localization prediction method of coalbursts is put forward. The relationship between energy release and absorption in the process of coalbursts is found, and the prevention and control methods of coalbursts, including the regional method, the local method and support, are presented. The safety evaluation index of coalburst prevention and control is put forward. The integrated prevention and control method for coal and gas outbursts is proposed. The prevention and control technology and equipment of coalbursts have also been developed. Amongst them, the distribution law of the critical stress in China coalburst mines is discovered. The technology and equipment for monitoring, prevention and control of coalbursts, as well as for integrated prevention and control of combined coalbursts and other disasters, have been developed. The energy-absorbing and coalburst-preventing support technology for roadways is invented, and key engineering parameters of coalburst prevention and control are pointed out. In China, coalburst prevention and control laws and standards have been developed. Technical standards for coalbursts are formulated, statute and regulations for coal mines are established, and regulatory documents are promoted. 展开更多
关键词 Coalbursts Rockbursts Dynamic disaster Energy-absorbing support Monitoring and early warning
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Machine learning-assisted efficient design of Cu-based shape memory alloy with specific phase transition temperature 被引量:2
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作者 Mengwei Wu Wei Yong +2 位作者 Cunqin Fu Chunmei Ma Ruiping Liu 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第4期773-785,共13页
The martensitic transformation temperature is the basis for the application of shape memory alloys(SMAs),and the ability to quickly and accurately predict the transformation temperature of SMAs has very important prac... The martensitic transformation temperature is the basis for the application of shape memory alloys(SMAs),and the ability to quickly and accurately predict the transformation temperature of SMAs has very important practical significance.In this work,machine learning(ML)methods were utilized to accelerate the search for shape memory alloys with targeted properties(phase transition temperature).A group of component data was selected to design shape memory alloys using reverse design method from numerous unexplored data.Component modeling and feature modeling were used to predict the phase transition temperature of the shape memory alloys.The experimental results of the shape memory alloys were obtained to verify the effectiveness of the support vector regression(SVR)model.The results show that the machine learning model can obtain target materials more efficiently and pertinently,and realize the accurate and rapid design of shape memory alloys with specific target phase transition temperature.On this basis,the relationship between phase transition temperature and material descriptors is analyzed,and it is proved that the key factors affecting the phase transition temperature of shape memory alloys are based on the strength of the bond energy between atoms.This work provides new ideas for the controllable design and performance optimization of Cu-based shape memory alloys. 展开更多
关键词 machine learning support vector regression shape memory alloys martensitic transformation temperature
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Analysis of the interaction between bolt-reinforced rock and surface support in tunnels based on convergence-confinement method 被引量:2
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作者 Zhenyu Sun Dingli Zhang +2 位作者 Qian Fang Yanjuan Hou Nanqi Huangfu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期1936-1951,共16页
To investigate the interaction of the bolt-reinforced rock and the surface support,an analytical model of the convergence-confinement type is proposed,considering the sequential installation of the fully grouted rockb... To investigate the interaction of the bolt-reinforced rock and the surface support,an analytical model of the convergence-confinement type is proposed,considering the sequential installation of the fully grouted rockbolts and the surface support.The rock mass is assumed to be elastic-brittle-plastic material,obeying the linear Mohr-Coulomb criterion or the non-linear Hoek-Brown criterion.According to the strain states of the tunnel wall at bolt and surface support installation and the relative magnitude between the bolt length and the plastic depth during the whole process,six cases are categorized upon solving the problem.Each case is divided into three stages due to the different effects of the active rockbolts and the passive surface support.The fictitious pressure is introduced to quantify the threedimensional(3D)effect of the tunnel face,and thus,the actual physical location along the tunnel axis of the analytical section can be considered.By using the bolt-rock strain compatibility and the rocksurface support displacement compatibility conditions,the solutions of longitudinal tunnel displacement and the reaction pressure of surface support along the tunnel axis are obtained.The proposed analytical solutions are validated by a series of 3D numerical simulations.Extensive parametric studies are conducted to examine the effect of the typical parameters of rockbolts and surface support on the tunnel displacement and the reaction pressure of the surface support under different rock conditions.The results show that the rockbolts are more effective in controlling the tunnel displacement than the surface support,which should be installed as soon as possible with a suitable length.For tunnels excavated in weak rocks or with restricted displacement control requirements,the surface support should also be installed or closed timely with a certain stiffness.The proposed method provides a convenient alternative approach for the optimization of rockbolts and surface support at the preliminary stage of tunnel design. 展开更多
关键词 Analytical model Longitudinal tunnel displacement Fictitious pressure Active rockbolts Surface support reaction pressure Tunnel design
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Dysfunctional attitudes,social support,negative life events,and depressive symptoms in Chinese adolescents:A moderated mediation model 被引量:2
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作者 Teng-Fei Yu Li Liu +3 位作者 Lu-Ning Shang Fang-Fang Xu Zhi-Min Chen Li-Ju Qian 《World Journal of Psychiatry》 SCIE 2024年第11期1671-1680,共10页
BACKGROUND Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events(NLEs)and dysfunctional attitudes.High levels of social support can significantly buffer NLE... BACKGROUND Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events(NLEs)and dysfunctional attitudes.High levels of social support can significantly buffer NLEs’effect on depression.Currently,there is limited research on how social support moderates the relationship between NLEs,dysfunctional attitudes,and depression in adolescents in China.It is imperative to investigate this moderating effect to mitigate dysfunctional attitudes in adolescent undergoing depressive mood,ultimately enhancing their overall mental health.AIM To investigate the relationship and underlying mechanisms between specific dysfunctional attitudes,social support,and depression among Chinese adolescents.METHODS This is a cross-sectional study which selected five middle schools in Shandong Province for investigation in March 2022.Participants included 795 adolescents(49.87%male,mage=15.15,SD=1.84,age range=11-18 years old).All participants completed the Dysfunctional Attitude Scale,Adolescent Life Event Scale,Beck Depression Inventory,and Social Support Rating Scale.A moderated mediation model was conducted to examine the relationship between specific dysfunctional attitudes,social support,and depression.RESULTS Results indicated that NLEs affected depression through the mediating role of specific dysfunctional attitudes(autonomy attitudesβ=0.21;perfectionismβ=0.25).Moreover,social support was found to moderate the mediating effect between NLEs,specific dysfunctional attitudes,and depressive symptoms(autonomy attitudes b2=-0.08;perfectionism b2=-0.09).CONCLUSION Dysfunctional attitudes mediated and social support moderated the relationship between NLEs and depression.Social support can buffer depression symptoms among adolescents with autonomy attitudes and perfectionism. 展开更多
关键词 DEPRESSION Dysfunctional attitudes Social support Adolescents Moderated mediation model
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Mechanism of high-preload support based on the NPR anchor cable in layered soft rock tunnels 被引量:1
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作者 SUI Qiru HE Manchao +3 位作者 SHI Mengfan TAO Zhigang ZHAO Feifei ZHANG Xiaoyu 《Journal of Mountain Science》 SCIE CSCD 2024年第4期1403-1418,共16页
The control of large deformation problems in layered soft rock tunnels needs to solve urgently.The roof problem is particularly severe among the deformation issues in tunnels.This study first analyzes the asymmetric d... The control of large deformation problems in layered soft rock tunnels needs to solve urgently.The roof problem is particularly severe among the deformation issues in tunnels.This study first analyzes the asymmetric deformation modes in layered soft rock tunnels with large deformations.Subsequently,we construct a mechanical model under ideal conditions for controlling the roof of layered soft rock tunnels through high preload with the support of NPR anchor cables.The prominent roles of long and short NPR anchor cables in the support system are also analyzed.The results indicate the significance of high preload in controlling the roof of layered soft rock tunnels.The short NPR anchor cables effectively improve the integrity of the stratified soft rock layers,while the long NPR anchor cables effectively mobilize the self-bearing capacity of deep-stable rock layers.Finally,the high-preload support method with NPR anchor cables is validated to have a good effect on controlling large deformations in layered soft rock tunnels through field monitoring data. 展开更多
关键词 Tunnel engineering Soft rock High-preload support NPR anchor cables
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From concept to commercialization:A review of tubular solid oxide fuel cell technology 被引量:1
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作者 Ruyan Chen Yuan Gao +4 位作者 Jiutao Gao Huiyu Zhang Martin Motola Muhammad Bilal Hanif Cheng-Xin Li 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第10期79-109,I0003,共32页
The reduced sealing difficulty of tubular solid oxide fuel cells(SOFCs)makes the stacking of tubular cell groups relatively easy,and the thermal stress constraints during stack operation are smaller,which helps the st... The reduced sealing difficulty of tubular solid oxide fuel cells(SOFCs)makes the stacking of tubular cell groups relatively easy,and the thermal stress constraints during stack operation are smaller,which helps the stack to operate stably for a long time.The special design of tubular SOFC structures can completely solve the problem of high-temperature sealing,especially in the design of multiple single-cell series integrated into one tube,where each cell tube is equivalent to a small electric stack,with unique characteristics of high voltage and low current output,which can significantly reduce the ohmic polarization loss of tubular cells.This paper provides an overview of typical tubular SOFC structural designs both domestically and internationally.Based on the geometric structure of tubular SOFCs,they can be divided into bamboo tubes,bamboo flat tubes,single-section tubes,and single-section flat tube structures.Meanwhile,this article provides an overview of commonly used materials and preparation methods for tubular SOFCs,including commonly used materials and preparation methods for support and functional layers,as well as a comparison of commonly used preparation methods for microtubule SOFCs,It introduced the three most important parts of building a fuel cell stack:manifold,current collector,and ceramic adhesive,and also provided a detailed introduction to the power generation systems of different tubular SOFCs,Finally,the development prospects of tubular SOFCs were discussed. 展开更多
关键词 Tubular solid oxide fuel cell Support material Geometric structure Preparation methods STACK
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Comparison of debris flow susceptibility assessment methods:support vector machine,particle swarm optimization,and feature selection techniques 被引量:1
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作者 ZHAO Haijun WEI Aihua +3 位作者 MA Fengshan DAI Fenggang JIANG Yongbing LI Hui 《Journal of Mountain Science》 SCIE CSCD 2024年第2期397-412,共16页
The selection of important factors in machine learning-based susceptibility assessments is crucial to obtain reliable susceptibility results.In this study,metaheuristic optimization and feature selection techniques we... The selection of important factors in machine learning-based susceptibility assessments is crucial to obtain reliable susceptibility results.In this study,metaheuristic optimization and feature selection techniques were applied to identify the most important input parameters for mapping debris flow susceptibility in the southern mountain area of Chengde City in Hebei Province,China,by using machine learning algorithms.In total,133 historical debris flow records and 16 related factors were selected.The support vector machine(SVM)was first used as the base classifier,and then a hybrid model was introduced by a two-step process.First,the particle swarm optimization(PSO)algorithm was employed to select the SVM model hyperparameters.Second,two feature selection algorithms,namely principal component analysis(PCA)and PSO,were integrated into the PSO-based SVM model,which generated the PCA-PSO-SVM and FS-PSO-SVM models,respectively.Three statistical metrics(accuracy,recall,and specificity)and the area under the receiver operating characteristic curve(AUC)were employed to evaluate and validate the performance of the models.The results indicated that the feature selection-based models exhibited the best performance,followed by the PSO-based SVM and SVM models.Moreover,the performance of the FS-PSO-SVM model was better than that of the PCA-PSO-SVM model,showing the highest AUC,accuracy,recall,and specificity values in both the training and testing processes.It was found that the selection of optimal features is crucial to improving the reliability of debris flow susceptibility assessment results.Moreover,the PSO algorithm was found to be not only an effective tool for hyperparameter optimization,but also a useful feature selection algorithm to improve prediction accuracies of debris flow susceptibility by using machine learning algorithms.The high and very high debris flow susceptibility zone appropriately covers 38.01%of the study area,where debris flow may occur under intensive human activities and heavy rainfall events. 展开更多
关键词 Chengde Feature selection Support vector machine Particle swarm optimization Principal component analysis Debris flow susceptibility
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Dynamic Hand Gesture-Based Person Identification Using Leap Motion and Machine Learning Approaches 被引量:1
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作者 Jungpil Shin Md.AlMehedi Hasan +2 位作者 Md.Maniruzzaman Taiki Watanabe Issei Jozume 《Computers, Materials & Continua》 SCIE EI 2024年第4期1205-1222,共18页
Person identification is one of the most vital tasks for network security. People are more concerned about theirsecurity due to traditional passwords becoming weaker or leaking in various attacks. In recent decades, f... Person identification is one of the most vital tasks for network security. People are more concerned about theirsecurity due to traditional passwords becoming weaker or leaking in various attacks. In recent decades, fingerprintsand faces have been widely used for person identification, which has the risk of information leakage as a resultof reproducing fingers or faces by taking a snapshot. Recently, people have focused on creating an identifiablepattern, which will not be reproducible falsely by capturing psychological and behavioral information of a personusing vision and sensor-based techniques. In existing studies, most of the researchers used very complex patternsin this direction, which need special training and attention to remember the patterns and failed to capturethe psychological and behavioral information of a person properly. To overcome these problems, this researchdevised a novel dynamic hand gesture-based person identification system using a Leap Motion sensor. Thisstudy developed two hand gesture-based pattern datasets for performing the experiments, which contained morethan 500 samples, collected from 25 subjects. Various static and dynamic features were extracted from the handgeometry. Randomforest was used to measure feature importance using the Gini Index. Finally, the support vectormachinewas implemented for person identification and evaluate its performance using identification accuracy. Theexperimental results showed that the proposed system produced an identification accuracy of 99.8% for arbitraryhand gesture-based patterns and 99.6% for the same dynamic hand gesture-based patterns. This result indicatedthat the proposed system can be used for person identification in the field of security. 展开更多
关键词 Person identification leap motion hand gesture random forest support vector machine
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Translocation of telomerase reverse transcriptase coincided with ATP release in postnatal cochlear supporting cells 被引量:1
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作者 Yukai Zhang Keyong Tian +9 位作者 Wei Wei Wenjuan Mi Fei Lu Zhenzhen Liu Qingwen Zhu Xinyu Zhang Panling Geng Jianhua Qiu Yongli Song Dingjun Zha 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第5期1119-1125,共7页
The spontaneous bursts of electrical activity in the developing auditory system are derived from the periodic release of adenosine triphosphate(ATP)by supporting cells in the Kölliker’s organ.However,the mechani... The spontaneous bursts of electrical activity in the developing auditory system are derived from the periodic release of adenosine triphosphate(ATP)by supporting cells in the Kölliker’s organ.However,the mechanisms responsible for initiating spontaneous ATP release have not been determined.Our previous study revealed that telomerase reverse transcriptase(TERT)is expressed in the basilar membrane during the first postnatal week.Its role in cochlear development remains unclear.In this study,we investigated the expression and role of TERT in postnatal cochlea supporting cells.Our results revealed that in postnatal cochlear Kölliker’s organ supporting cells,TERT shifts from the nucleus into the cytoplasm over time.We found that the TERT translocation tendency in postnatal cochlear supporting cells in vitro coincided with that observed in vivo.Further analysis showed that TERT in the cytoplasm was mainly located in mitochondria in the absence of oxidative stress or apoptosis,suggesting that TERT in mitochondria plays roles other than antioxidant or anti-apoptotic functions.We observed increased ATP synthesis,release and activation of purine signaling systems in supporting cells during the first 10 postnatal days.The phenomenon that TERT translocation coincided with changes in ATP synthesis,release and activation of the purine signaling system in postnatal cochlear supporting cells suggested that TERT may be involved in regulating ATP release and activation of the purine signaling system.Our study provides a new research direction for exploring the spontaneous electrical activity of the cochlea during the early postnatal period. 展开更多
关键词 apoptosis ATP release Ca2+transients COCHLEA mitochondrial function reactive oxygen species spontaneous electrical activity supporting cells
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开挖补偿法防控深部地下岩爆灾害——引汉济渭工程秦岭输水隧洞案例分析 被引量:1
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作者 Jie Hu Manchao He +4 位作者 Hongru Li Zhigang Tao Dongqiao Liu Tai Cheng Di Peng 《Engineering》 SCIE EI CAS CSCD 2024年第3期154-163,共10页
Rockburst disasters occur frequently during deep underground excavation,yet traditional concepts and methods can hardly meet the requirements for support under high geo-stress conditions.Consequently,rockburst control... Rockburst disasters occur frequently during deep underground excavation,yet traditional concepts and methods can hardly meet the requirements for support under high geo-stress conditions.Consequently,rockburst control remains challenging in the engineering field.In this study,the mechanism of excavation-induced rockburst was briefly described,and it was proposed to apply the excavation compensation method(ECM)to rockburst control.Moreover,a field test was carried out on the Qinling Water Conveyance Tunnel.The following beneficial findings were obtained:Excavation leads to changes in the engineering stress state of surrounding rock and results in the generation of excess energy DE,which is the fundamental cause of rockburst.The ECM,which aims to offset the deep excavation effect and lower the risk of rockburst,is an active support strategy based on high pre-stress compensation.The new negative Poisson’s ratio(NPR)bolt developed has the mechanical characteristics of high strength,high toughness,and impact resistance,serving as the material basis for the ECM.The field test results reveal that the ECM and the NPR bolt succeed in controlling rockburst disasters effectively.The research results are expected to provide guidance for rockburst support in deep underground projects such as Sichuan-Xizang Railway. 展开更多
关键词 ROCKBURST Excavation compensation method Pre-stressed support Negative Poisson’s ratio bolt Tunnel boring machine
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Stability analysis of longwall top-coal caving face in extra-thick coal seams based on an innovative numerical hydraulic support model 被引量:1
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作者 Jun Guo Wenbo Huang +7 位作者 Guorui Feng Jinwen Bai Lirong Li Zi Wang Luyang Yu Xiaoze Wen Jie Zhang Wenming Feng 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第4期491-505,共15页
The relationship between support and surrounding rock is of great significance to the control of surrounding rock in mining process.In view of the fact that most of the existing numerical simulation methods construct ... The relationship between support and surrounding rock is of great significance to the control of surrounding rock in mining process.In view of the fact that most of the existing numerical simulation methods construct virtual elements and stress servo control to approximately replace the hydraulic support problem,this paper establishes a new numerical model of hydraulic support with the same working characteristics as the actual hydraulic support by integrating numerical simulation software Rhino,Griddle and FLAC3D,which can realize the simulation of different working conditions.Based on this model,the influence mechanism of the supporting strength of hydraulic support on surrounding rock stress regulation and coal stability in front of the top coal caving face in extra thick coal seam were researched.Firstly,under different support intensity,the abutment pressure of the bearing coal and the coal in front of it presents the “three-stage”evolution characteristics.The influence range of support intensity is 15%–30%.Secondly,1.5 MPa is the upper limit of impact that the support strength can have on the front coal failure area.Thirdly,within a displacement range of 2.76 m from the coal wall,a support strength of1.5 MPa provides optimal control of the horizontal displacement of the coal. 展开更多
关键词 Extremely thick coal seam Fully mechanized top coal caving Support strength Support-surrounding rock interaction
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Coupling Analysis of Multiple Machine Learning Models for Human Activity Recognition 被引量:1
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作者 Yi-Chun Lai Shu-Yin Chiang +1 位作者 Yao-Chiang Kan Hsueh-Chun Lin 《Computers, Materials & Continua》 SCIE EI 2024年第6期3783-3803,共21页
Artificial intelligence(AI)technology has become integral in the realm of medicine and healthcare,particularly in human activity recognition(HAR)applications such as fitness and rehabilitation tracking.This study intr... Artificial intelligence(AI)technology has become integral in the realm of medicine and healthcare,particularly in human activity recognition(HAR)applications such as fitness and rehabilitation tracking.This study introduces a robust coupling analysis framework that integrates four AI-enabled models,combining both machine learning(ML)and deep learning(DL)approaches to evaluate their effectiveness in HAR.The analytical dataset comprises 561 features sourced from the UCI-HAR database,forming the foundation for training the models.Additionally,the MHEALTH database is employed to replicate the modeling process for comparative purposes,while inclusion of the WISDM database,renowned for its challenging features,supports the framework’s resilience and adaptability.The ML-based models employ the methodologies including adaptive neuro-fuzzy inference system(ANFIS),support vector machine(SVM),and random forest(RF),for data training.In contrast,a DL-based model utilizes one-dimensional convolution neural network(1dCNN)to automate feature extraction.Furthermore,the recursive feature elimination(RFE)algorithm,which drives an ML-based estimator to eliminate low-participation features,helps identify the optimal features for enhancing model performance.The best accuracies of the ANFIS,SVM,RF,and 1dCNN models with meticulous featuring process achieve around 90%,96%,91%,and 93%,respectively.Comparative analysis using the MHEALTH dataset showcases the 1dCNN model’s remarkable perfect accuracy(100%),while the RF,SVM,and ANFIS models equipped with selected features achieve accuracies of 99.8%,99.7%,and 96.5%,respectively.Finally,when applied to the WISDM dataset,the DL-based and ML-based models attain accuracies of 91.4%and 87.3%,respectively,aligning with prior research findings.In conclusion,the proposed framework yields HAR models with commendable performance metrics,exhibiting its suitability for integration into the healthcare services system through AI-driven applications. 展开更多
关键词 Human activity recognition artificial intelligence support vector machine random forest adaptive neuro-fuzzy inference system convolution neural network recursive feature elimination
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Enhancing Cancer Classification through a Hybrid Bio-Inspired Evolutionary Algorithm for Biomarker Gene Selection 被引量:1
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作者 Hala AlShamlan Halah AlMazrua 《Computers, Materials & Continua》 SCIE EI 2024年第4期675-694,共20页
In this study,our aim is to address the problem of gene selection by proposing a hybrid bio-inspired evolutionary algorithm that combines Grey Wolf Optimization(GWO)with Harris Hawks Optimization(HHO)for feature selec... In this study,our aim is to address the problem of gene selection by proposing a hybrid bio-inspired evolutionary algorithm that combines Grey Wolf Optimization(GWO)with Harris Hawks Optimization(HHO)for feature selection.Themotivation for utilizingGWOandHHOstems fromtheir bio-inspired nature and their demonstrated success in optimization problems.We aimto leverage the strengths of these algorithms to enhance the effectiveness of feature selection in microarray-based cancer classification.We selected leave-one-out cross-validation(LOOCV)to evaluate the performance of both two widely used classifiers,k-nearest neighbors(KNN)and support vector machine(SVM),on high-dimensional cancer microarray data.The proposed method is extensively tested on six publicly available cancer microarray datasets,and a comprehensive comparison with recently published methods is conducted.Our hybrid algorithm demonstrates its effectiveness in improving classification performance,Surpassing alternative approaches in terms of precision.The outcomes confirm the capability of our method to substantially improve both the precision and efficiency of cancer classification,thereby advancing the development ofmore efficient treatment strategies.The proposed hybridmethod offers a promising solution to the gene selection problem in microarray-based cancer classification.It improves the accuracy and efficiency of cancer diagnosis and treatment,and its superior performance compared to other methods highlights its potential applicability in realworld cancer classification tasks.By harnessing the complementary search mechanisms of GWO and HHO,we leverage their bio-inspired behavior to identify informative genes relevant to cancer diagnosis and treatment. 展开更多
关键词 Bio-inspired algorithms BIOINFORMATICS cancer classification evolutionary algorithm feature selection gene expression grey wolf optimizer harris hawks optimization k-nearest neighbor support vector machine
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Assessment of soil erosion in the Irga watershed on the eastern edge of the Chota Nagpur Plateau,India 被引量:1
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作者 Ratan PAL Buddhadev HEMBRAM Narayan Chandra JANA 《Regional Sustainability》 2024年第1期54-68,共15页
Human activities to improve the quality of life have accelerated the natural rate of soil erosion.In turn,these natural disasters have taken a great impact on humans.Human activities,particularly the conversion of veg... Human activities to improve the quality of life have accelerated the natural rate of soil erosion.In turn,these natural disasters have taken a great impact on humans.Human activities,particularly the conversion of vegetated land into agricultural land and built-up area,stand out as primary contributors to soil erosion.The present study investigated the risk of soil erosion in the Irga watershed located on the eastern fringe of the Chota Nagpur Plateau in Jharkhand,India,which is dominated by sandy loam and sandy clay loam soil with low soil organic carbon(SOC)content.The study used the Revised Universal Soil Loss Equation(RUSLE)and Geographical Information System(GIS)technique to determine the rate of soil erosion.The five parameters(rainfall-runoff erosivity(R)factor,soil erodibility(K)factor,slope length and steepness(LS)factor,cover-management(C)factor,and support practice(P)factor)of the RUSLE were applied to present a more accurate distribution characteristic of soil erosion in the Irga watershed.The result shows that the R factor is positively correlated with rainfall and follows the same distribution pattern as the rainfall.The K factor values in the northern part of the study area are relatively low,while they are relatively high in the southern part.The mean value of the LS factor is 2.74,which is low due to the flat terrain of the Irga watershed.There is a negative linear correlation between Normalized Difference Vegetation Index(NDVI)and the C factor,and the high values of the C factor are observed in places with low NDVI.The mean value of the P factor is 0.210,with a range from 0.000 to 1.000.After calculating all parameters,we obtained the average soil erosion rate of 1.43 t/(hm^(2)•a),with the highest rate reaching as high as 32.71 t/(hm^(2)•a).Therefore,the study area faces a low risk of soil erosion.However,preventative measures are essential to avoid future damage to productive and constructive activities caused by soil erosion.This study also identifies the spatial distribution of soil erosion rate,which will help policy-makers to implement targeted soil erosion control measures. 展开更多
关键词 Soil erosion Soil organic carbon Rainfall-runoff erosivity factor Soil erodibility factor Slope length and steepness factor Cover-management factor Support practice factor Irga watershed
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