Mg has received much attention as a next-generation implantable material owing to its biocompatibility,bone-like mechanical properties,and biodegradability in physiological environments.The application of various poly...Mg has received much attention as a next-generation implantable material owing to its biocompatibility,bone-like mechanical properties,and biodegradability in physiological environments.The application of various polymer coatings has been conducted in the past to reduce the rapid formation of hydrogen gas and the local change in pH during the initial phase of the chemical reaction with the body fluids.Here,we propose femtosecond(fs)laser-mediated Mg surface patterning for significant enhancement of the binding strength of the coating material,which eventually reduces the corrosion rate.Analyses of the structural,physical,crystallographic,and chemical properties of the Mg surface have been conducted in order to understand the mechanism by which the surface adhesion increases between Mg and the polymer coating layer.Depending on the fs laser conditions,the surface structure becomes rough owing to the presence of several microscaled pits and grooves of nanoporous MgO,resulting in a tightly bonded poly(lactic-co-glycolic acid)(PLGA)layer.The corrosion rate of the PLGA-coated,fs laser-treated Mg is considerably slow compared with the non-treated Mg;the treated Mg is also more biocompatible compared with the non-treated Mg.The fs laser-based surface modification technique offers a simple and quick method for introducing a rough coating on Mg;further,it does not require any chemical treatment,thereby overcoming a potential obstacle for its clinical use.展开更多
Premature failure of coated tool often results from a poor adhesion of coating-substrate and shortens the lifetime of the tool. The results of increasing the adhesion strength of thin film coatings on cutting tool ins...Premature failure of coated tool often results from a poor adhesion of coating-substrate and shortens the lifetime of the tool. The results of increasing the adhesion strength of thin film coatings on cutting tool inserts by pretreating the inserts with sandblasting technique to obtain a desirable surface morphology of the inserts are presented. A geometric model representing the ideal surface morphology is established to enhance the nucleation density and adhesion strength of coating-substrate. Thin film coating experiment is conducted on the substrates of four different sample groups. Indentation and wear tests are performed on coated inserts to evaluate the effect of sandblasting on the adhesion strength of the coatings. A theoretical analysis is provided on the formation and growth of atom clusters in terms of the contact angle and the thermodynamic barrier of a substrate to predict thin film nucleation.展开更多
The size mismatch in an end-to-end vascular anastomosis between the host vessel and the graft may cause flow disturbance and predispose to thrombosis [1].Although a number of techniques have been employed to reduce th...The size mismatch in an end-to-end vascular anastomosis between the host vessel and the graft may cause flow disturbance and predispose to thrombosis [1].Although a number of techniques have been employed to reduce the risk of anastomotic thrombosis due to the size mismatch。展开更多
Wedge-shaped microstructures have the ability to reproduce the excellent adhesive properties of geckos’feet because of their unique anisotropic structure.In particular,the controllability of the wedge-shaped microstr...Wedge-shaped microstructures have the ability to reproduce the excellent adhesive properties of geckos’feet because of their unique anisotropic structure.In particular,the controllability of the wedge-shaped microstructures on adhesion is beneficial to the undisturbed grasp or the capture of space targets.However,the problem currently remains of how to process it efficiently and with high quality.Here a strategy called ultraprecision multistep and layered scribing is proposed for the manufacture of the biomimetic controllable adhesive surface.The results show that the metal master mold prepared based on the manufacturing strategy has not only good surface topography but also high reliability and durability.Furthermore,the controllable adhesive surface of 1.96 cm2,fabricated by the proposed manufacturing strategy,has a normal adhesion of 1.012 N,and the corresponding shear friction and adhesion coefficient are 3.105 N and 4.82,respectively.Additionally,the controllable adhesive surface has been shown to be approximately superhydrophobic and also to possess the properties of controllable adhesion and dynamic adhesion.Also,after 250 adhesion-detachment cycles,the normal adhesion and shear friction only decrease by 5%and 3%,respectively.The research realizes an environmentally friendly and efficient method by which to manufacture a durable metal mold for fabricating a biomimetic controllable adhesive surface,laying a foundation for its effective application in the adherence of space-floating targets.展开更多
Gecko has the ability to climb flexibly on various natural surfaces because of its fine layered adhesion system of foot,which has motivated researchers to carry out a lot of researches on it.Significant progresses hav...Gecko has the ability to climb flexibly on various natural surfaces because of its fine layered adhesion system of foot,which has motivated researchers to carry out a lot of researches on it.Significant progresses have been made in the gecko-like dry adhesive surfaces in the past 2 decades,such as the mechanical measurement of adhesive characteristics,the theoretical modeling of adhesive mechanism and the production of synthetic dry adhesive surfaces.Relevant application researches have been carried out as well.This paper focuses on the investigations made in recent years on the gecko-like dry adhesive surfaces,so as to lay the foundation for further research breakthroughs.First,the adhesion system of gecko’s foot and its excellent adhesive characteristics are reviewed,and the adhesive models describing the gecko adhesion are summarily reviewed according to the diff erent contact modes.Then,some gecko-like dry adhesive surfaces with outstanding adhesive characteristics are presented.Next,some application researches based on the gecko-like dry adhesive surfaces are introduced.Finally,the full text is summarized and the problems to be solved on the gecko-like dry adhesive surfaces are prospected.展开更多
It has shown that altering crosslink density of biopolymers will regulate the morphology of Mesenchymal Stem Cells (MSCs) and the subsequent MSCs differentia- tion. These observations have been found in a wide range...It has shown that altering crosslink density of biopolymers will regulate the morphology of Mesenchymal Stem Cells (MSCs) and the subsequent MSCs differentia- tion. These observations have been found in a wide range of biopolymers. However, a recent work published in Nature Materials has revealed that MSCs morphology and differen- tiation was unaffected by crosslink density of polydimethyl- siloxane (PDMS), which remains elusive. To understand such unusual behaviour, we use nanoindentation tests and modelling to characterize viscoelastic properties and sur- face adhesion of PDMS with different base:crosslink ratio varied from 50:1 (50D) to 10:1 (10D). It has shown that lower crosslink density leads to lower elastic moduli. De- spite lower nanoindentation elastic moduli, PDMS with lowest crosslink density has higher local surface adhesion which would affect cell-biomaterials interactions. This work suggests that surface adhesion is likely another important physical cue to regulate cell-biomaterials interactions.展开更多
基金This work was supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.2020R1A2C2010413)the KIST project(2E30341)。
文摘Mg has received much attention as a next-generation implantable material owing to its biocompatibility,bone-like mechanical properties,and biodegradability in physiological environments.The application of various polymer coatings has been conducted in the past to reduce the rapid formation of hydrogen gas and the local change in pH during the initial phase of the chemical reaction with the body fluids.Here,we propose femtosecond(fs)laser-mediated Mg surface patterning for significant enhancement of the binding strength of the coating material,which eventually reduces the corrosion rate.Analyses of the structural,physical,crystallographic,and chemical properties of the Mg surface have been conducted in order to understand the mechanism by which the surface adhesion increases between Mg and the polymer coating layer.Depending on the fs laser conditions,the surface structure becomes rough owing to the presence of several microscaled pits and grooves of nanoporous MgO,resulting in a tightly bonded poly(lactic-co-glycolic acid)(PLGA)layer.The corrosion rate of the PLGA-coated,fs laser-treated Mg is considerably slow compared with the non-treated Mg;the treated Mg is also more biocompatible compared with the non-treated Mg.The fs laser-based surface modification technique offers a simple and quick method for introducing a rough coating on Mg;further,it does not require any chemical treatment,thereby overcoming a potential obstacle for its clinical use.
基金This project is Supported by National Science Foundation of China (No.59475090)National Science Foundation of USA (No.DDM-93-9669)
文摘Premature failure of coated tool often results from a poor adhesion of coating-substrate and shortens the lifetime of the tool. The results of increasing the adhesion strength of thin film coatings on cutting tool inserts by pretreating the inserts with sandblasting technique to obtain a desirable surface morphology of the inserts are presented. A geometric model representing the ideal surface morphology is established to enhance the nucleation density and adhesion strength of coating-substrate. Thin film coating experiment is conducted on the substrates of four different sample groups. Indentation and wear tests are performed on coated inserts to evaluate the effect of sandblasting on the adhesion strength of the coatings. A theoretical analysis is provided on the formation and growth of atom clusters in terms of the contact angle and the thermodynamic barrier of a substrate to predict thin film nucleation.
基金supported by Grants-in-Aid from the National Natural Science Foundation of China No.10632010,30670517
文摘The size mismatch in an end-to-end vascular anastomosis between the host vessel and the graft may cause flow disturbance and predispose to thrombosis [1].Although a number of techniques have been employed to reduce the risk of anastomotic thrombosis due to the size mismatch。
基金supported by the Major Research Plan of the National Natural Science Foundation of China(Grant No.91848202)。
文摘Wedge-shaped microstructures have the ability to reproduce the excellent adhesive properties of geckos’feet because of their unique anisotropic structure.In particular,the controllability of the wedge-shaped microstructures on adhesion is beneficial to the undisturbed grasp or the capture of space targets.However,the problem currently remains of how to process it efficiently and with high quality.Here a strategy called ultraprecision multistep and layered scribing is proposed for the manufacture of the biomimetic controllable adhesive surface.The results show that the metal master mold prepared based on the manufacturing strategy has not only good surface topography but also high reliability and durability.Furthermore,the controllable adhesive surface of 1.96 cm2,fabricated by the proposed manufacturing strategy,has a normal adhesion of 1.012 N,and the corresponding shear friction and adhesion coefficient are 3.105 N and 4.82,respectively.Additionally,the controllable adhesive surface has been shown to be approximately superhydrophobic and also to possess the properties of controllable adhesion and dynamic adhesion.Also,after 250 adhesion-detachment cycles,the normal adhesion and shear friction only decrease by 5%and 3%,respectively.The research realizes an environmentally friendly and efficient method by which to manufacture a durable metal mold for fabricating a biomimetic controllable adhesive surface,laying a foundation for its effective application in the adherence of space-floating targets.
基金supported by the Major Research Plan of the National Natural Science Foundation of China[Grant number 91848202]supported by the Self-Planned Task of State Key Laboratory of Robotics and System(HIT)[Grant number SKLRS202106B].
文摘Gecko has the ability to climb flexibly on various natural surfaces because of its fine layered adhesion system of foot,which has motivated researchers to carry out a lot of researches on it.Significant progresses have been made in the gecko-like dry adhesive surfaces in the past 2 decades,such as the mechanical measurement of adhesive characteristics,the theoretical modeling of adhesive mechanism and the production of synthetic dry adhesive surfaces.Relevant application researches have been carried out as well.This paper focuses on the investigations made in recent years on the gecko-like dry adhesive surfaces,so as to lay the foundation for further research breakthroughs.First,the adhesion system of gecko’s foot and its excellent adhesive characteristics are reviewed,and the adhesive models describing the gecko adhesion are summarily reviewed according to the diff erent contact modes.Then,some gecko-like dry adhesive surfaces with outstanding adhesive characteristics are presented.Next,some application researches based on the gecko-like dry adhesive surfaces are introduced.Finally,the full text is summarized and the problems to be solved on the gecko-like dry adhesive surfaces are prospected.
基金funded by EPSRC–Newcastle University Sandpit Workshop Award
文摘It has shown that altering crosslink density of biopolymers will regulate the morphology of Mesenchymal Stem Cells (MSCs) and the subsequent MSCs differentia- tion. These observations have been found in a wide range of biopolymers. However, a recent work published in Nature Materials has revealed that MSCs morphology and differen- tiation was unaffected by crosslink density of polydimethyl- siloxane (PDMS), which remains elusive. To understand such unusual behaviour, we use nanoindentation tests and modelling to characterize viscoelastic properties and sur- face adhesion of PDMS with different base:crosslink ratio varied from 50:1 (50D) to 10:1 (10D). It has shown that lower crosslink density leads to lower elastic moduli. De- spite lower nanoindentation elastic moduli, PDMS with lowest crosslink density has higher local surface adhesion which would affect cell-biomaterials interactions. This work suggests that surface adhesion is likely another important physical cue to regulate cell-biomaterials interactions.
基金This work was supported by the National and Jiangsu Province Natural Science Foundation(Grant Nos.T2293691,T2293692,and BK20212008)of ChinaNational Key Research and Development Program of China(Grant No.2019YFA0705400)+3 种基金China Postdoctoral Science Foundation(Grant No.2021M701703)Jiangsu Funding Program for Excellent postdoctoral talent(Grant No.2022ZB211),the Research Fund of State Key Laboratory of Mechanics and Control of Mechanical Structures(Grant No.MCMS-I-0422K01)the Fundamental Research Funds for the Central Universities(Grant No.NJ2022002)the Fund of Prospective Layout of Scientific Research for NUAA(Nanjing University of Aeronautics and Astronautics).