A simple technique for sensitive detection of heroine based on surface- plasmonresonance has been theoretically and experimentally investigated. The experiment was realized by using an anti-MO monoclonal antibody and ...A simple technique for sensitive detection of heroine based on surface- plasmonresonance has been theoretically and experimentally investigated. The experiment was realized by using an anti-MO monoclonal antibody and a morphine (MO)-bovine serum albumin (MOBSA) conjugate (antigen). The reason for using MO-BSA in the detection of heroine was also discussed. MO-BSA was immobilized on a gold thin film of SPR sensor chip by physical adsorption. The configuration of the device is allowed to be further miniaturized, which is required for the construction of a portable SPR device in the application of in-situ analysis.展开更多
A high sensitivity D-shaped hole double-cladding fiber temperature sensor based on surface plasmon resonance(SPR)is designed and investigated by a full-vector finite element method.Within the D-shaped hole doublecladd...A high sensitivity D-shaped hole double-cladding fiber temperature sensor based on surface plasmon resonance(SPR)is designed and investigated by a full-vector finite element method.Within the D-shaped hole doublecladding fiber,the hollow D-section is coated with gold film and then injected in a high thermo-optic coefficient liquid to realize the high temperature sensitivity for the fiber SPR temperature sensor.The numerical simulation results show that the peaking loss of the D-shaped hole double-cladding fiber SPR is hugely influenced by the distance between the D-shaped hole and fiber core and by the thickness of the gold film,but the temperature sensitivity is almost insensitive to the above parameters.When the thermo-optic coefficient is -2.8×10^(-4)∕℃,the thickness of the gold film is 47 nm,and the distance between the D-shaped hole and fiber core is 5μm,the temperature sensitivity of the D-shaped hole fiber SPR sensor can reach to -3.635 nm∕℃.展开更多
文摘A simple technique for sensitive detection of heroine based on surface- plasmonresonance has been theoretically and experimentally investigated. The experiment was realized by using an anti-MO monoclonal antibody and a morphine (MO)-bovine serum albumin (MOBSA) conjugate (antigen). The reason for using MO-BSA in the detection of heroine was also discussed. MO-BSA was immobilized on a gold thin film of SPR sensor chip by physical adsorption. The configuration of the device is allowed to be further miniaturized, which is required for the construction of a portable SPR device in the application of in-situ analysis.
基金National Natural Science Foundation of China(NSFC)(61525501)
文摘A high sensitivity D-shaped hole double-cladding fiber temperature sensor based on surface plasmon resonance(SPR)is designed and investigated by a full-vector finite element method.Within the D-shaped hole doublecladding fiber,the hollow D-section is coated with gold film and then injected in a high thermo-optic coefficient liquid to realize the high temperature sensitivity for the fiber SPR temperature sensor.The numerical simulation results show that the peaking loss of the D-shaped hole double-cladding fiber SPR is hugely influenced by the distance between the D-shaped hole and fiber core and by the thickness of the gold film,but the temperature sensitivity is almost insensitive to the above parameters.When the thermo-optic coefficient is -2.8×10^(-4)∕℃,the thickness of the gold film is 47 nm,and the distance between the D-shaped hole and fiber core is 5μm,the temperature sensitivity of the D-shaped hole fiber SPR sensor can reach to -3.635 nm∕℃.
