The purpose of this paper is to present a general universal formula for <span style="font-family:Verdana;"><i></i></span><i><span><span><i><span style="...The purpose of this paper is to present a general universal formula for <span style="font-family:Verdana;"><i></i></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;">-variate survival functions for arbitrary </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> = 2, 3, </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">...</span><span style="font-family:Verdana;">, given all the univariate marginal survival functions. This universal form of </span></span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;">-variate probability distributions was obtained by means of “dependence functions” named “joiners” in the text. These joiners determine all the involved stochastic dependencies between the underlying random variables. However, in order that the presented formula (the form) represents a legitimate survival function, some necessary and sufficient conditions for the joiners had to be found. Basically, finding those conditions is the main task of this paper. This task was successfully performed for the case </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;"> = 2 and the main results for the case </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;"> = 3 were formulated as Theorem 1 and Theorem 2 in Section 4. Nevertheless, the hypothetical conditions valid for the general </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;"> ≥ 4 case were also formulated in Section 3 as the (very convincing) Hypothesis. As for the sufficient conditions for both the </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> = 3 and</span><i> </i></span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;"> ≥ 4 cases, the full generality was not achieved since two restrictions were imposed. Firstly, we limited ourselves to the, defined in the text, “continuous cases” (when the corresponding joint density exists and is continuous), and secondly we consider positive stochastic dependencies only. Nevertheless, the class of the </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;">-variate distributions which can be constructed is very wide. The presented method of construction by means of joiners can be considered competitive to the </span><span style="font-family:Verdana;"><strong></strong></span></span></span><strong><span><span><b><span style="font-family:Verdana;">copula</span></b><span style="font-family:Verdana;"></span></span></span></strong><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> methodology. As it is suggested in the paper the possibility of building a common theory of both copulae and joiners is quite possible, and the joiners may play the role of tools within the theory of copulae, and vice versa copulae may, for example, be used for finding proper joiners. Another independent feature of the joiners methodology is the possibility of constructing many new stochastic processes including stationary and Markovian.</span></span></span>展开更多
The reliability of power transformers is subject to service age and health condition.This paper proposes a practical model for the evaluation of two reliability indices:survival function(SF)and mean residual life(MRL)...The reliability of power transformers is subject to service age and health condition.This paper proposes a practical model for the evaluation of two reliability indices:survival function(SF)and mean residual life(MRL).In the proposed model,the periodical modeling of power transformers are considered for collecting the information on health conditions.The corresponding health condition is assumed to follow a continuous semi-Markov process for representing a state transition.The proportional hazard model(PHM)is introduced to incorporate service age and health condition into hazard rate.In addition,the proposed model derives the analytical formulas for and offers the analytical evaluation of SF and MRL.SF and MRL are calculated for new components and old components,respectively.In both cases,the proposed model offers rational results which are compared with those obtained from comparative models.The results obtained by the contrast of the proposed analytical method and the Monte Carlo method.The impact of differentmodel parameters and the coefficient of variation(CV)on reliability indices are discussed in the case studies.展开更多
Cox Proportional Hazard model is a popular statistical technique for exploring the relationship between the survival time of neonates and several explanatory variables. It provides an estimate of the study variables’...Cox Proportional Hazard model is a popular statistical technique for exploring the relationship between the survival time of neonates and several explanatory variables. It provides an estimate of the study variables’ effect on survival after adjustment for other explanatory variables, and allows us to estimate the hazard (or risk) of death of newborn in NICU of hospitals in River Nile State-Sudan for the period (2018-2020). Study Data represented (neonate gender, mode of delivery, birth type, neonate weight, resident type, gestational age, and survival time). Kaplan-Meier method is used to estimate survival and hazard function for survival times of newborns that have not completed their first month. Of 700 neonates in the study area, 25% of them died during 2018-2020. Variables of interest that had a significant effect on neonatal death by Cox Proportional Hazard Model analysis were neonate weight, resident type, and gestational age. In Cox Proportional Hazard Model analysis all the variables of interest had an effect on neonatal death, but the variables with a significant effect included, weight of neonate, resident type and gestational age.展开更多
This paper concerns the Log-rank test for comparing survival curves of neonatal mortality characteristic groups in River Nile State, Sudan. In this paper, log-rank test is used to compare two or more survival curves f...This paper concerns the Log-rank test for comparing survival curves of neonatal mortality characteristic groups in River Nile State, Sudan. In this paper, log-rank test is used to compare two or more survival curves for the characteristics of newborn associated with newborn death after using Kaplan-Meier methods to estimate and graph survival curves for the variable of interest as (sex of newborn, weight of newborn, gestational age, mode of delivery and resident type), at the hospital of River Nile state—Sudan, with a sample size 700 of newborn in which the admission to the Neonatal Intensive Care Unit (NICU) of those hospitals during the period 2018-2020. In term of risk of death for newborn we found that 25% of sample study for newborns who were born in River Nile State-Sudan died. In addition, we conclude that after the log-rank statistics and Kaplan-Meier methods were applied, gender does not affect the newborn’s risk of survival, while the risk of survival increases when the birth weight is greater than 4.35 kg and the gestational age is greater than 42 weeks. There is no difference in the probability of survival for newborns whether the delivery is normal or cesarean. However, newborns are significantly more likely to survive in urban areas than in rural areas.展开更多
Objective To compare the effects of combined en bloc liver - pancreas transplantation ( LPT) with portal vein drainage and simultaneous combined kidney - pancreas transplantation ( KPT) with systemic venous drainage o...Objective To compare the effects of combined en bloc liver - pancreas transplantation ( LPT) with portal vein drainage and simultaneous combined kidney - pancreas transplantation ( KPT) with systemic venous drainage on the pancreatic endocrine function and related me-展开更多
This study has provided a starting point for defining and working with Cox models in respect of multivariate modeling. In medical researches, there may be situations, where several risk factors potentially affect pati...This study has provided a starting point for defining and working with Cox models in respect of multivariate modeling. In medical researches, there may be situations, where several risk factors potentially affect patient prognosis, howbeit, only one or two might predict patient’s predicament. In seeking to find out which of the risk factors contribute the most to the survival times of patients, there was the need for researchers to adjust the covariates to realize their impact on survival times of patients. Aside the multivariate nature of the covariates, some covariates might be categorical while others might be quantitative. Again, there might be cases where researchers need a model that has <span style="font-family:Verdana;">the capability of extending survival analysis methods to assessing simulta</span><span style="font-family:Verdana;">neously the effect of several risk factors on survival times. This study unveiled the Cox model as a robust technique which could accomplish the aforementioned cases.</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">An investigation meant to evaluate the ITN-factor vis-à-vis its </span><span style="font-family:Verdana;">contribution towards death due to Malaria was exemplified with the Cox model. Data were taken from hospitals in Ghana. In doing so, we assessed hospital in-patients who reported cases of malaria (origin state) to time until death or censoring (destination stage) as a result of predictive factors (exposure to the malaria parasites) and some socioeconomic variables. We purposefully used Cox models to quantify the effect of the ITN-factor in the presence of other risk factors to obtain some measures of effect that could describe the rela</span><span style="font-family:Verdana;">tionship between the exposure variable and time until death adjusting for</span><span style="font-family:Verdana;"> other variables. PH assumption holds for all three covariates. Sex of patient was insignificant to deaths due to malaria. Age of patient and user status </span></span><span style="font-family:Verdana;">were</span><span style="font-family:Verdana;"> both significant. The magnitude of the coefficient (0.384) of ITN user status depicts its high contribution to the variation in the dependent variable.</span>展开更多
The convolution of Nadarajah-Haghighi-G family of distributions will result <span style="font-family:Verdana;">into a more flexible distribution (Nadarajah-Haghighi Gompertz distribution) </span>...The convolution of Nadarajah-Haghighi-G family of distributions will result <span style="font-family:Verdana;">into a more flexible distribution (Nadarajah-Haghighi Gompertz distribution) </span><span style="font-family:Verdana;">than each of them individually in terms of the estimate of the characteristics in there parameters. The combination was done using Nadarajah-Haghighi </span><span style="font-family:Verdana;">(NH) generator. We investigated in the newly developed distribution some basic </span><span style="font-family:Verdana;">properties including moment, moment generating function, survival rate function, hazard rate function asymptotic behaviour and estimation of parameters. The proposed model is much more flexible and has a better representation of data than Gompertz distribution and some other model considered. A real data set was used to illustrate the applicability of the new model.</span>展开更多
The random weighting method is an emerging computing method in statistics.In this paper,we propose a novel estimation of the survival function for right censored data based on the random weighting method.Under some re...The random weighting method is an emerging computing method in statistics.In this paper,we propose a novel estimation of the survival function for right censored data based on the random weighting method.Under some regularity conditions,we prove the strong consistency of this estimation.展开更多
We present a new nonparametric predictive inference(NPI)method using a power-normal model for accelerated life testing(ALT).Combined with the accelerating link function and imprecise probability theory,the proposed me...We present a new nonparametric predictive inference(NPI)method using a power-normal model for accelerated life testing(ALT).Combined with the accelerating link function and imprecise probability theory,the proposed method is a feasible way to predict the life of the product using ALT failure data.To validate the method,we run a series of simulations and conduct accelerated life tests with real products.The NPI lower and upper survival functions show the robustness of our method for life prediction.This is a continuous research,and some progresses have been made by updating the link function between different stress levels.We also explain how to renew and apply our model.Moreover,discussions have been made about the performance.展开更多
文摘The purpose of this paper is to present a general universal formula for <span style="font-family:Verdana;"><i></i></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;">-variate survival functions for arbitrary </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> = 2, 3, </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">...</span><span style="font-family:Verdana;">, given all the univariate marginal survival functions. This universal form of </span></span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;">-variate probability distributions was obtained by means of “dependence functions” named “joiners” in the text. These joiners determine all the involved stochastic dependencies between the underlying random variables. However, in order that the presented formula (the form) represents a legitimate survival function, some necessary and sufficient conditions for the joiners had to be found. Basically, finding those conditions is the main task of this paper. This task was successfully performed for the case </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;"> = 2 and the main results for the case </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;"> = 3 were formulated as Theorem 1 and Theorem 2 in Section 4. Nevertheless, the hypothetical conditions valid for the general </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;"> ≥ 4 case were also formulated in Section 3 as the (very convincing) Hypothesis. As for the sufficient conditions for both the </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> = 3 and</span><i> </i></span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;"> ≥ 4 cases, the full generality was not achieved since two restrictions were imposed. Firstly, we limited ourselves to the, defined in the text, “continuous cases” (when the corresponding joint density exists and is continuous), and secondly we consider positive stochastic dependencies only. Nevertheless, the class of the </span><span style="font-family:Verdana;"><i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">k</span></i><span style="font-family:Verdana;"></span></span></span></i><span><span><span style="font-family:Verdana;">-variate distributions which can be constructed is very wide. The presented method of construction by means of joiners can be considered competitive to the </span><span style="font-family:Verdana;"><strong></strong></span></span></span><strong><span><span><b><span style="font-family:Verdana;">copula</span></b><span style="font-family:Verdana;"></span></span></span></strong><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> methodology. As it is suggested in the paper the possibility of building a common theory of both copulae and joiners is quite possible, and the joiners may play the role of tools within the theory of copulae, and vice versa copulae may, for example, be used for finding proper joiners. Another independent feature of the joiners methodology is the possibility of constructing many new stochastic processes including stationary and Markovian.</span></span></span>
文摘The reliability of power transformers is subject to service age and health condition.This paper proposes a practical model for the evaluation of two reliability indices:survival function(SF)and mean residual life(MRL).In the proposed model,the periodical modeling of power transformers are considered for collecting the information on health conditions.The corresponding health condition is assumed to follow a continuous semi-Markov process for representing a state transition.The proportional hazard model(PHM)is introduced to incorporate service age and health condition into hazard rate.In addition,the proposed model derives the analytical formulas for and offers the analytical evaluation of SF and MRL.SF and MRL are calculated for new components and old components,respectively.In both cases,the proposed model offers rational results which are compared with those obtained from comparative models.The results obtained by the contrast of the proposed analytical method and the Monte Carlo method.The impact of differentmodel parameters and the coefficient of variation(CV)on reliability indices are discussed in the case studies.
文摘Cox Proportional Hazard model is a popular statistical technique for exploring the relationship between the survival time of neonates and several explanatory variables. It provides an estimate of the study variables’ effect on survival after adjustment for other explanatory variables, and allows us to estimate the hazard (or risk) of death of newborn in NICU of hospitals in River Nile State-Sudan for the period (2018-2020). Study Data represented (neonate gender, mode of delivery, birth type, neonate weight, resident type, gestational age, and survival time). Kaplan-Meier method is used to estimate survival and hazard function for survival times of newborns that have not completed their first month. Of 700 neonates in the study area, 25% of them died during 2018-2020. Variables of interest that had a significant effect on neonatal death by Cox Proportional Hazard Model analysis were neonate weight, resident type, and gestational age. In Cox Proportional Hazard Model analysis all the variables of interest had an effect on neonatal death, but the variables with a significant effect included, weight of neonate, resident type and gestational age.
文摘This paper concerns the Log-rank test for comparing survival curves of neonatal mortality characteristic groups in River Nile State, Sudan. In this paper, log-rank test is used to compare two or more survival curves for the characteristics of newborn associated with newborn death after using Kaplan-Meier methods to estimate and graph survival curves for the variable of interest as (sex of newborn, weight of newborn, gestational age, mode of delivery and resident type), at the hospital of River Nile state—Sudan, with a sample size 700 of newborn in which the admission to the Neonatal Intensive Care Unit (NICU) of those hospitals during the period 2018-2020. In term of risk of death for newborn we found that 25% of sample study for newborns who were born in River Nile State-Sudan died. In addition, we conclude that after the log-rank statistics and Kaplan-Meier methods were applied, gender does not affect the newborn’s risk of survival, while the risk of survival increases when the birth weight is greater than 4.35 kg and the gestational age is greater than 42 weeks. There is no difference in the probability of survival for newborns whether the delivery is normal or cesarean. However, newborns are significantly more likely to survive in urban areas than in rural areas.
文摘Objective To compare the effects of combined en bloc liver - pancreas transplantation ( LPT) with portal vein drainage and simultaneous combined kidney - pancreas transplantation ( KPT) with systemic venous drainage on the pancreatic endocrine function and related me-
文摘This study has provided a starting point for defining and working with Cox models in respect of multivariate modeling. In medical researches, there may be situations, where several risk factors potentially affect patient prognosis, howbeit, only one or two might predict patient’s predicament. In seeking to find out which of the risk factors contribute the most to the survival times of patients, there was the need for researchers to adjust the covariates to realize their impact on survival times of patients. Aside the multivariate nature of the covariates, some covariates might be categorical while others might be quantitative. Again, there might be cases where researchers need a model that has <span style="font-family:Verdana;">the capability of extending survival analysis methods to assessing simulta</span><span style="font-family:Verdana;">neously the effect of several risk factors on survival times. This study unveiled the Cox model as a robust technique which could accomplish the aforementioned cases.</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">An investigation meant to evaluate the ITN-factor vis-à-vis its </span><span style="font-family:Verdana;">contribution towards death due to Malaria was exemplified with the Cox model. Data were taken from hospitals in Ghana. In doing so, we assessed hospital in-patients who reported cases of malaria (origin state) to time until death or censoring (destination stage) as a result of predictive factors (exposure to the malaria parasites) and some socioeconomic variables. We purposefully used Cox models to quantify the effect of the ITN-factor in the presence of other risk factors to obtain some measures of effect that could describe the rela</span><span style="font-family:Verdana;">tionship between the exposure variable and time until death adjusting for</span><span style="font-family:Verdana;"> other variables. PH assumption holds for all three covariates. Sex of patient was insignificant to deaths due to malaria. Age of patient and user status </span></span><span style="font-family:Verdana;">were</span><span style="font-family:Verdana;"> both significant. The magnitude of the coefficient (0.384) of ITN user status depicts its high contribution to the variation in the dependent variable.</span>
文摘The convolution of Nadarajah-Haghighi-G family of distributions will result <span style="font-family:Verdana;">into a more flexible distribution (Nadarajah-Haghighi Gompertz distribution) </span><span style="font-family:Verdana;">than each of them individually in terms of the estimate of the characteristics in there parameters. The combination was done using Nadarajah-Haghighi </span><span style="font-family:Verdana;">(NH) generator. We investigated in the newly developed distribution some basic </span><span style="font-family:Verdana;">properties including moment, moment generating function, survival rate function, hazard rate function asymptotic behaviour and estimation of parameters. The proposed model is much more flexible and has a better representation of data than Gompertz distribution and some other model considered. A real data set was used to illustrate the applicability of the new model.</span>
文摘The random weighting method is an emerging computing method in statistics.In this paper,we propose a novel estimation of the survival function for right censored data based on the random weighting method.Under some regularity conditions,we prove the strong consistency of this estimation.
基金the National Natural Science Foundation of China(No.11272082)the China Scholarship Council State Scholarship Fund(No.201506070017)
文摘We present a new nonparametric predictive inference(NPI)method using a power-normal model for accelerated life testing(ALT).Combined with the accelerating link function and imprecise probability theory,the proposed method is a feasible way to predict the life of the product using ALT failure data.To validate the method,we run a series of simulations and conduct accelerated life tests with real products.The NPI lower and upper survival functions show the robustness of our method for life prediction.This is a continuous research,and some progresses have been made by updating the link function between different stress levels.We also explain how to renew and apply our model.Moreover,discussions have been made about the performance.